PubMed

STAT3 in CD4+ T helper cell differentiation and inflammatory diseases.

Egwuagu CE.

Cytokine. 2009 Sep;47(3):149-56. Epub 2009 Aug 3. Review.PMID: 19648026 [PubMed - indexed for MEDLINE]Related articles

SOCS1 regulates CCR7 expression and migration of CD4+ T cells into peripheral tissues.

Yu CR, Mahdi RM, Liu X, Zhang A, Naka T, Kishimoto T, Egwuagu CE.

J Immunol. 2008 Jul 15;181(2):1190-8.PMID: 18606672 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of STAT3 in CD4+ T cells prevents development of experimental autoimmune diseases.

Liu X, Lee YS, Yu CR, Egwuagu CE.

J Immunol. 2008 May 1;180(9):6070-6.PMID: 18424728 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppressors of cytokine-signaling proteins induce insulin resistance in the retina and promote survival of retinal cells.

Liu X, Mameza MG, Lee YS, Eseonu CI, Yu CR, Kang Derwent JJ, Egwuagu CE.

Diabetes. 2008 Jun;57(6):1651-8. Epub 2008 Mar 20.PMID: 18356406 [PubMed - indexed for MEDLINE]Related articlesFree article

TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1.

Amadi-Obi A, Yu CR, Liu X, Mahdi RM, Clarke GL, Nussenblatt RB, Gery I, Lee YS, Egwuagu CE.

Nat Med. 2007 Jun;13(6):711-8. Epub 2007 May 13.PMID: 17496900 [PubMed - indexed for MEDLINE]Related articles

Cytokine-induced retinal degeneration: role of suppressors of cytokine signaling (SOCS) proteins in protection of the neuroretina.

Egwuagu CE, Yu CH, Mahdi RM, Mameza M, Eseonu C, Takase H, Ebong S.

Adv Exp Med Biol. 2006;572:275-81. No abstract available. PMID: 17249584 [PubMed - indexed for MEDLINE]Related articles

Pertussis toxin is superior to TLR ligands in enhancing pathogenic autoimmunity, targeted at a neo-self antigen, by triggering robust expansion of Th1 cells and their cytokine production.

Fujimoto C, Yu CR, Shi G, Vistica BP, Wawrousek EF, Klinman DM, Chan CC, Egwuagu CE, Gery I.

J Immunol. 2006 Nov 15;177(10):6896-903.PMID: 17082604 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of SOCS1 and SOCS3 genes is differentially regulated in breast cancer cells in response to proinflammatory cytokine and growth factor signals.

Evans MK, Yu CR, Lohani A, Mahdi RM, Liu X, Trzeciak AR, Egwuagu CE.

Oncogene. 2007 Mar 22;26(13):1941-8. Epub 2006 Sep 25.PMID: 17001312 [PubMed - indexed for MEDLINE]Related articles

Inflammatory processes triggered by TCR engagement or by local cytokine expression: differences in profiles of gene expression and infiltrating cell populations.

Takase H, Yu CR, Ham DI, Chan CC, Chen J, Vistica BP, Wawrousek EF, Durum SK, Egwuagu CE, Gery I.

J Leukoc Biol. 2006 Sep;80(3):538-45. Epub 2006 Jun 22.PMID: 16793919 [PubMed - indexed for MEDLINE]Related articlesFree article

The level of thymic expression of RPE65 inversely correlates with its capacity to induce experimental autoimmune uveitis (EAU) in different rodent strains.

Ham DI, Fujimoto C, Gentleman S, Chan CC, Yu CR, Yu S, Egwuagu CE, Michael Redmond T, Gery I.

Exp Eye Res. 2006 Oct;83(4):897-902. Epub 2006 Jun 13.PMID: 16777093 [PubMed - indexed for MEDLINE]Related articles

Interferon-gamma induces regression of epithelial cell carcinoma: critical roles of IRF-1 and ICSBP transcription factors.

Egwuagu CE, Li W, Yu CR, Che Mei Lin M, Chan CC, Nakamura T, Chepelinsky AB.

Oncogene. 2006 Jun 22;25(26):3670-9. Epub 2006 Feb 6.PMID: 16462767 [PubMed - indexed for MEDLINE]Related articles

Induction of suppressors of cytokine signaling (SOCS) in the retina during experimental autoimmune uveitis (EAU): potential neuroprotective role of SOCS proteins.

Takase H, Yu CR, Liu X, Fujimoto C, Gery I, Egwuagu CE.

J Neuroimmunol. 2005 Nov;168(1-2):118-27.PMID: 16154209 [PubMed - indexed for MEDLINE]Related articles

Thymic expression of peripheral tissue antigens in humans: a remarkable variability among individuals.

Takase H, Yu CR, Mahdi RM, Douek DC, Dirusso GB, Midgley FM, Dogra R, Allende G, Rosenkranz E, Pugliese A, Egwuagu CE, Gery I.

Int Immunol. 2005 Aug;17(8):1131-40. Epub 2005 Jul 19.PMID: 16030131 [PubMed - indexed for MEDLINE]Related articlesFree article

SOCS5 mRNA levels in peripheral blood mononuclear cells (PBMC): a potential bio-marker for monitoring response of uveitis patients to Daclizumab therapy.

Egwuagu CE, Yu CR, Li Z, Nussenblatt RB.

J Autoimmun. 2005 Feb;24(1):39-46. Epub 2005 Jan 27.PMID: 15725575 [PubMed - indexed for MEDLINE]Related articles

Cell proliferation and STAT6 pathways are negatively regulated in T cells by STAT1 and suppressors of cytokine signaling.

Yu CR, Mahdi RM, Ebong S, Vistica BP, Chen J, Guo Y, Gery I, Egwuagu CE.

J Immunol. 2004 Jul 15;173(2):737-46.PMID: 15240659 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of STAT signaling pathways and induction of suppressors of cytokine signaling (SOCS) proteins in mammalian lens by growth factors.

Ebong S, Yu CR, Carper DA, Chepelinsky AB, Egwuagu CE.

Invest Ophthalmol Vis Sci. 2004 Mar;45(3):872-8.PMID: 14985304 [PubMed - indexed for MEDLINE]Related articlesFree article

Central immunotolerance in transgenic mice expressing a foreign antigen under control of the rhodopsin promoter.

Ham DI, Kim SJ, Chen J, Vistica BP, Fariss RN, Lee RS, Wawrousek EF, Takase H, Yu CR, Egwuagu CE, Chan CC, Gery I.

Invest Ophthalmol Vis Sci. 2004 Mar;45(3):857-62.PMID: 14985302 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the roles of STAT1 and STAT3 signal transduction pathways in mammalian lens development.

Ebong S, Chepelinsky AB, Robinson ML, Zhao H, Yu CR, Egwuagu CE.

Mol Vis. 2004 Feb 19;10:122-31.PMID: 14978477 [PubMed - indexed for MEDLINE]Related articlesFree article

Dendritic cell maturation requires STAT1 and is under feedback regulation by suppressors of cytokine signaling.

Jackson SH, Yu CR, Mahdi RM, Ebong S, Egwuagu CE.

J Immunol. 2004 Feb 15;172(4):2307-15.PMID: 14764699 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunotolerance toward native alphaA-crystallin in knockout mice deficient in the functional protein.

Charukamnoetkanok P, Brady JP, Wawrousek EF, Egwuagu CE, Zigler JS Jr, Vistica BP, Whitcup SM, Gery I.

Immunol Lett. 2003 Oct 31;89(2-3):259-65. Erratum in: Immunol Lett. 2003 Dec 15;90(2-3):229. PMID: 14556987 [PubMed - indexed for MEDLINE]Related articles

Suppressor of cytokine signaling 3 regulates proliferation and activation of T-helper cells.

Yu CR, Mahdi RM, Ebong S, Vistica BP, Gery I, Egwuagu CE.

J Biol Chem. 2003 Aug 8;278(32):29752-9. Epub 2003 Jun 2.PMID: 12783879 [PubMed - indexed for MEDLINE]Related articlesFree article

T cell tolerance to a neo-self antigen expressed by thymic epithelial cells: the soluble form is more effective than the membrane-bound form.

Zhang M, Vacchio MS, Vistica BP, Lesage S, Egwuagu CE, Yu CR, Gelderman MP, Kennedy MC, Wawrousek EF, Gery I.

J Immunol. 2003 Apr 15;170(8):3954-62.PMID: 12682222 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-4 synergistically enhances both IL-2- and IL-12-induced IFN-gamma expression in murine NK cells.

Bream JH, Curiel RE, Yu CR, Egwuagu CE, Grusby MJ, Aune TM, Young HA.

Blood. 2003 Jul 1;102(1):207-14. Epub 2003 Mar 13.PMID: 12637316 [PubMed - indexed for MEDLINE]Related articlesFree article

Central tolerance mechanisms in control of susceptibility to autoimmune uveitic disease.

Gery I, Egwuagu CE.

Int Rev Immunol. 2002 Mar-Jun;21(2-3):89-100. Review. No abstract available. PMID: 12424838 [PubMed - indexed for MEDLINE]Related articles

Immunoproteasome expression in a nonimmune tissue, the ocular lens.

Singh S, Awasthi N, Egwuagu CE, Wagner BJ.

Arch Biochem Biophys. 2002 Sep 15;405(2):147-53.PMID: 12220526 [PubMed - indexed for MEDLINE]Related articles

Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: implications for Th cell lineage commitment and maintenance.

Egwuagu CE, Yu CR, Zhang M, Mahdi RM, Kim SJ, Gery I.

J Immunol. 2002 Apr 1;168(7):3181-7.PMID: 11907070 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection of Toxoplasma gondii DNA in primary intraocular B-cell lymphoma.

Shen DF, Herbort CP, Tuaillon N, Buggage RR, Egwuagu CE, Chan CC.

Mod Pathol. 2001 Oct;14(10):995-9.PMID: 11598169 [PubMed - indexed for MEDLINE]Related articlesFree article

Skewed abrogation of tolerance to a neo self-antigen in double-transgenic mice coexpressing the antigen with interleukin-1beta or interferon-gamma.

Zhang M, Fukushima A, Vistica BP, Kim SJ, Hung L, Wawrousek EF, Egwuagu CE, Lee RS, Whitcup SM, Gery I.

Cell Immunol. 2001 Jan 10;207(1):6-12.PMID: 11161447 [PubMed - indexed for MEDLINE]Related articles

Susceptibility to ocular autoimmune disease.

Egwuagu CE, Charukamnoetkanok P, Gery I.

Br J Ophthalmol. 2000 Sep;84(9):1084. No abstract available. PMID: 10966976 [PubMed - indexed for MEDLINE]Related articlesFree article

Interferon regulatory transcription factors are constitutively expressed and spatially regulated in the mouse lens.

Li W, Nagineni CN, Efiok B, Chepelinsky AB, Egwuagu CE.

Dev Biol. 1999 Jun 1;210(1):44-55.PMID: 10364426 [PubMed - indexed for MEDLINE]Related articles

Expression of interferon-gamma in the lens exacerbates anterior uveitis and induces retinal degenerative changes in transgenic Lewis rats.

Egwuagu CE, Mahdi RM, Chan CC, Sztein J, Li W, Smith JA, Chepelinsky AB.

Clin Immunol. 1999 May;91(2):196-205.PMID: 10227812 [PubMed - indexed for MEDLINE]Related articles

Interferon-gamma signaling in human retinal pigment epithelial cells mediated by STAT1, ICSBP, and IRF-1 transcription factors.

Li W, Nagineni CN, Hooks JJ, Chepelinsky AB, Egwuagu CE.

Invest Ophthalmol Vis Sci. 1999 Apr;40(5):976-82.PMID: 10102295 [PubMed - indexed for MEDLINE]Related articlesFree article

Interferon consensus sequence-binding protein is constitutively expressed and differentially regulated in the ocular lens.

Li W, Nagineni CN, Ge H, Efiok B, Chepelinsky AB, Egwuagu CE.

J Biol Chem. 1999 Apr 2;274(14):9686-91.PMID: 10092656 [PubMed - indexed for MEDLINE]Related articlesFree article

IFN-gamma increases the severity and accelerates the onset of experimental autoimmune uveitis in transgenic rats.

Egwuagu CE, Sztein J, Mahdi RM, Li W, Chao-Chan C, Smith JA, Charukamnoetkanok P, Chepelinsky AB.

J Immunol. 1999 Jan 1;162(1):510-7.PMID: 9886427 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunotolerance against a foreign antigen transgenically expressed in the lens.

Lai JC, Fukushima A, Wawrousek EF, Lobanoff MC, Charukamnoetkanok P, Smith-Gill SJ, Vistica BP, Lee RS, Egwuagu CE, Whitcup SM, Gery I.

Invest Ophthalmol Vis Sci. 1998 Oct;39(11):2049-57.PMID: 9761283 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of ocular autoantigens in the mouse thymus.

Charukamnoetkanok P, Fukushima A, Whitcup SM, Gery I, Egwuagu CE.

Curr Eye Res. 1998 Aug;17(8):788-92.PMID: 9723993 [PubMed - indexed for MEDLINE]Related articles

Immunohistochemical examination of lacrimal gland tissue from patients with ocular sarcoidosis.

Smith JA, Chan CC, Egwuagu CE, Whitcup SM.

Adv Exp Med Biol. 1998;438:599-602. No abstract available. PMID: 9634942 [PubMed - indexed for MEDLINE]Related articles

Thymic expression of autoantigens correlates with resistance to autoimmune disease.

Egwuagu CE, Charukamnoetkanok P, Gery I.

J Immunol. 1997 Oct 1;159(7):3109-12.PMID: 9317106 [PubMed - indexed for MEDLINE]Related articles

Extralenticular expression of the alpha A-crystallin promoter/gamma interferon transgene.

Egwuagu CE, Chepelinsky AB.

Exp Eye Res. 1997 Mar;64(3):491-5. No abstract available. PMID: 9196402 [PubMed - indexed for MEDLINE]Related articles

Synthesis and analysis of the enantiomers of calmidazolium, and a 1H NMR demonstration of a chiral interaction with calmodulin.

Edwards AJ, Sweeney PJ, Reid DG, Walker JM, Elshourbagy N, Egwuagu CE, Young JF, Patton CL.

Chirality. 1996;8(8):545-50.PMID: 9025254 [PubMed - indexed for MEDLINE]Related articles

gamma Interferon expression disrupts lens and retinal differentiation in transgenic mice.

Egwuagu CE, Sztein J, Chan CC, Mahdi R, Nussenblatt RB, Chepelinsky AB.

Dev Biol. 1994 Dec;166(2):557-68.PMID: 7813776 [PubMed - indexed for MEDLINE]Related articles

A pathogenic autoimmune process targeted at a surrogate epitope.

Kozhich AT, Kawano Y, Egwuagu CE, Caspi RR, Maturi RK, Berzofsky JA, Gery I.

J Exp Med. 1994 Jul 1;180(1):133-40.PMID: 7516403 [PubMed - indexed for MEDLINE]Related articlesFree article

Ectopic expression of gamma interferon in the eyes of transgenic mice induces ocular pathology and MHC class II gene expression.

Egwuagu CE, Sztein J, Chan CC, Reid W, Mahdi R, Nussenblatt RB, Chepelinsky AB.

Invest Ophthalmol Vis Sci. 1994 Feb;35(2):332-41.PMID: 8112978 [PubMed - indexed for MEDLINE]Related articlesFree article

Bacterial optic disk mass and toxoplasmic-like encephalitis in an HIV-seropositive subject.

Mansour AM, Ansari NH, Egwuagu CE, Kaspar HG, Harmon MK.

Graefes Arch Clin Exp Ophthalmol. 1993 Nov;231(11):668-71. No abstract available. PMID: 8258404 [PubMed - indexed for MEDLINE]Related articles

Evidence for selective accumulation of V beta 8+ T lymphocytes in experimental autoimmune uveoretinitis induced with two different retinal antigens.

Egwuagu CE, Mahdi RM, Nussenblatt RB, Gery I, Caspi RR.

J Immunol. 1993 Aug 1;151(3):1627-36.PMID: 8393049 [PubMed - indexed for MEDLINE]Related articles

Miliary toxoplasmic retinitis in acquired immunodeficiency syndrome.

Berger BB, Egwuagu CE, Freeman WR, Wiley CA.

Arch Ophthalmol. 1993 Mar;111(3):373-6.PMID: 8447750 [PubMed - indexed for MEDLINE]Related articles

Predominant usage of V beta 8.3 T cell receptor in a T cell line that induces experimental autoimmune uveoretinitis (EAU).

Egwuagu CE, Bahmanyar S, Mahdi RM, Nussenblatt RB, Gery I, Caspi RR.

Clin Immunol Immunopathol. 1992 Nov;65(2):152-60.PMID: 1382911 [PubMed - indexed for MEDLINE]Related articles

T cell receptor beta-chain usage in experimental autoimmune uveoretinitis.

Egwuagu CE, Chow C, Beraud E, Caspi RR, Mahdi RM, Brézin AP, Nussenblatt RB, Gery I.

J Autoimmun. 1991 Apr;4(2):315-24.PMID: 1652969 [PubMed - indexed for MEDLINE]Related articles

Identification of Toxoplasma gondii in paraffin-embedded sections by the polymerase chain reaction.

Brézin AP, Egwuagu CE, Burnier M Jr, Silveira C, Mahdi RM, Gazzinelli RT, Belfort R Jr, Nussenblatt RB.

Am J Ophthalmol. 1990 Dec 15;110(6):599-604.PMID: 2248322 [PubMed - indexed for MEDLINE]Related articles