PubMed

Adenovirus E3 MHC inhibitory genes but not TNF/Fas apoptotic inhibitory genes expressed in beta cells prevent autoimmune diabetes.

Horwitz MS, Efrat S, Christen U, von Herrath MG, Oldstone MB.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19450-4. Epub 2009 Nov 3.PMID: 19887639 [PubMed - in process]Related articles

Epithelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells.

Russ HA, Ravassard P, Kerr-Conte J, Pattou F, Efrat S.

PLoS One. 2009 Jul 29;4(7):e6417.PMID: 19641613 [PubMed - indexed for MEDLINE]Related articlesFree article

Infant toilet training.

Tali S, Efrat SU, Boucke L, Rugolotto S.

J Pediatr (Rio J). 2009 Jan-Feb;85(1):87-8; author reply 88-9. English, Portuguese. No abstract available. PMID: 19198745 [PubMed - indexed for MEDLINE]Related articlesFree article

Ex-vivo Expansion of Adult Human Pancreatic Beta-Cells.

Efrat S.

Rev Diabet Stud. 2008 Summer;5(2):116-22. Epub 2008 Aug 10.PMID: 18795214 [PubMed - in process]Related articlesFree article

HES-1 is involved in adaptation of adult human beta-cells to proliferation in vitro.

Bar Y, Russ HA, Knoller S, Ouziel-Yahalom L, Efrat S.

Diabetes. 2008 Sep;57(9):2413-20. Epub 2008 Jul 3.PMID: 18599525 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro expansion of human beta cells.

Efrat S.

Diabetologia. 2008 Jul;51(7):1338-9. Epub 2008 Apr 29. No abstract available. PMID: 18443759 [PubMed - indexed for MEDLINE]Related articles

In vitro proliferation of cells derived from adult human beta-cells revealed by cell-lineage tracing.

Russ HA, Bar Y, Ravassard P, Efrat S.

Diabetes. 2008 Jun;57(6):1575-83. Epub 2008 Mar 3.PMID: 18316362 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell replacement for insulin-dependent diabetes mellitus.

Efrat S.

Adv Drug Deliv Rev. 2008 Jan 14;60(2):114-23. Epub 2007 Oct 11. Review.PMID: 18022276 [PubMed - indexed for MEDLINE]Related articles

Generation of insulin-producing cells from human bone marrow mesenchymal stem cells by genetic manipulation.

Karnieli O, Izhar-Prato Y, Bulvik S, Efrat S.

Stem Cells. 2007 Nov;25(11):2837-44. Epub 2007 Jul 5.PMID: 17615265 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-producing cells from tissue stem/progenitor cells: are autologous cells preferable to allogeneic?

Efrat S.

Rev Diabet Stud. 2005 Spring;2(1):6-8. Epub 2005 May 10. No abstract available. PMID: 17491653 [PubMed]Related articlesFree article

Lineage tracing evidence for in vitro dedifferentiation but rare proliferation of mouse pancreatic beta-cells.

Weinberg N, Ouziel-Yahalom L, Knoller S, Efrat S, Dor Y.

Diabetes. 2007 May;56(5):1299-304. Epub 2007 Feb 15.PMID: 17303800 [PubMed - indexed for MEDLINE]Related articlesFree article

Knowledge, beliefs, and economic barriers to healthcare: a survey of diabetic patients in an Arab-Israeli town.

Khatib M, Efrat S, Deeb D.

J Ambul Care Manage. 2007 Jan-Mar;30(1):79-85.PMID: 17170641 [PubMed - indexed for MEDLINE]Related articles

Expansion and redifferentiation of adult human pancreatic islet cells.

Ouziel-Yahalom L, Zalzman M, Anker-Kitai L, Knoller S, Bar Y, Glandt M, Herold K, Efrat S.

Biochem Biophys Res Commun. 2006 Mar 10;341(2):291-8. Epub 2006 Jan 19.PMID: 16446152 [PubMed - indexed for MEDLINE]Related articles

Differentiation of human liver-derived, insulin-producing cells toward the beta-cell phenotype.

Zalzman M, Anker-Kitai L, Efrat S.

Diabetes. 2005 Sep;54(9):2568-75.PMID: 16123344 [PubMed - indexed for MEDLINE]Related articlesFree article

Baculovirus p35 increases pancreatic beta-cell resistance to apoptosis.

Hollander K, Bar-Chen M, Efrat S.

Biochem Biophys Res Commun. 2005 Jul 1;332(2):550-6.PMID: 15896716 [PubMed - indexed for MEDLINE]Related articles

Inhibition of islet amyloid polypeptide fibril formation: a potential role for heteroaromatic interactions.

Porat Y, Mazor Y, Efrat S, Gazit E.

Biochemistry. 2004 Nov 16;43(45):14454-62.PMID: 15533050 [PubMed - indexed for MEDLINE]Related articles

Generation of surrogate beta cells from tissue stem cells.

Efrat S.

Curr Diab Rep. 2004 Aug;4(4):298-303. Review.PMID: 15265473 [PubMed - indexed for MEDLINE]Related articles

Regulation of insulin secretion: insights from engineered beta-cell lines.

Efrat S.

Ann N Y Acad Sci. 2004 Apr;1014:88-96. Review.PMID: 15153423 [PubMed - indexed for MEDLINE]Related articles

Generation of insulin-producing cells from stem cells for cell replacement therapy of type 1 diabetes.

Efrat S.

Isr Med Assoc J. 2004 May;6(5):265-7. Review.PMID: 15151363 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells.

Zalzman M, Gupta S, Giri RK, Berkovich I, Sappal BS, Karnieli O, Zern MA, Fleischer N, Efrat S.

Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7253-8. Epub 2003 May 19.PMID: 12756298 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell expansion for therapeutic compensation of insulin resistance in type 2 diabetes.

Efrat S.

Int J Exp Diabesity Res. 2003 Jan-Mar;4(1):1-5. Review.PMID: 12745664 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenovirus early region 3 antiapoptotic 10.4K, 14.5K, and 14.7K genes decrease the incidence of autoimmune diabetes in NOD mice.

Pierce MA, Chapman HD, Post CM, Svetlanov A, Efrat S, Horwitz M, Serreze DV.

Diabetes. 2003 May;52(5):1119-27.PMID: 12716741 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell replacement therapy for type 1 diabetes.

Efrat S.

Trends Mol Med. 2002 Jul;8(7):334-39. Review.PMID: 12114113 [PubMed - indexed for MEDLINE]Related articles

Preventing type 1 diabetes mellitus: the promise of gene therapy.

Efrat S.

Am J Pharmacogenomics. 2002;2(2):129-34. Review.PMID: 12083947 [PubMed - indexed for MEDLINE]Related articles

Growth factor-dependent proliferation of the pancreatic beta-cell line betaTC-tet: an assay for beta-cell mitogenic factors.

Milo-Landesman D, Efrat S.

Int J Exp Diabetes Res. 2002;3(1):69-74.PMID: 11900281 [PubMed - indexed for MEDLINE]Related articlesFree article

Correction of hyperglycemia in diabetic mice transplanted with reversibly immortalized pancreatic beta cells controlled by the tet-on regulatory system.

Milo-Landesman D, Surana M, Berkovich I, Compagni A, Christofori G, Fleischer N, Efrat S.

Cell Transplant. 2001;10(7):645-50.PMID: 11714200 [PubMed - indexed for MEDLINE]Related articles

Inducible and reversible beta-cell autoimmunity and hyperplasia in transgenic mice expressing a conditional oncogene.

Berkovich I, Efrat S.

Diabetes. 2001 Oct;50(10):2260-7.PMID: 11574407 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell therapy approaches for the treatment of diabetes.

Efrat S.

Curr Opin Investig Drugs. 2001 May;2(5):639-42. Review.PMID: 11569939 [PubMed - indexed for MEDLINE]Related articles

Adenovirus early region 3(E3) immunomodulatory genes decrease the incidence of autoimmune diabetes in NOD mice.

Efrat S, Serreze D, Svetlanov A, Post CM, Johnson EA, Herold K, Horwitz M.

Diabetes. 2001 May;50(5):980-4.PMID: 11334441 [PubMed - indexed for MEDLINE]Related articlesFree article

Prospects for treatment of type 2 diabetes by expansion of the beta-cell mass.

Efrat S.

Diabetes. 2001 Feb;50 Suppl 1:S189-90. No abstract available. PMID: 11272191 [PubMed - indexed for MEDLINE]Related articles

Development of engineered pancreatic beta-cell lines for cell therapy of diabetes.

Efrat S.

Adv Drug Deliv Rev. 1998 Aug 3;33(1-2):45-52.PMID: 10837652 [PubMed - as supplied by publisher]Related articles

Genes induced by growth arrest in a pancreatic beta cell line: identification by analysis of cDNA arrays.

Zimmer Y, Milo-Landesman D, Svetlanov A, Efrat S.

FEBS Lett. 1999 Aug 20;457(1):65-70.PMID: 10486565 [PubMed - indexed for MEDLINE]Related articles

Genetically engineered pancreatic beta-cell lines for cell therapy of diabetes.

Efrat S.

Ann N Y Acad Sci. 1999 Jun 18;875:286-93. Review.PMID: 10415575 [PubMed - indexed for MEDLINE]Related articles

Prospects for gene therapy of insulin-dependent diabetes mellitus.

Efrat S.

Diabetologia. 1998 Dec;41(12):1401-9. Review.PMID: 9867206 [PubMed - indexed for MEDLINE]Related articles

Exendin-(9-39) is an inverse agonist of the murine glucagon-like peptide-1 receptor: implications for basal intracellular cyclic adenosine 3',5'-monophosphate levels and beta-cell glucose competence.

Serre V, Dolci W, Schaerer E, Scrocchi L, Drucker D, Efrat S, Thorens B.

Endocrinology. 1998 Nov;139(11):4448-54.PMID: 9794451 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional analysis of a conditionally transformed pancreatic beta-cell line.

Fleischer N, Chen C, Surana M, Leiser M, Rossetti L, Pralong W, Efrat S.

Diabetes. 1998 Sep;47(9):1419-25.PMID: 9726230 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell-based therapy for insulin-dependent diabetes mellitus.

Efrat S.

Eur J Endocrinol. 1998 Feb;138(2):129-33. Review.PMID: 9506853 [PubMed - indexed for MEDLINE]Related articlesFree article

Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele.

Rossetti L, Chen W, Hu M, Hawkins M, Barzilai N, Efrat S.

Am J Physiol. 1997 Oct;273(4 Pt 1):E743-50.PMID: 9357804 [PubMed - indexed for MEDLINE]Related articlesFree article

Making sense of glucose sensing.

Efrat S.

Nat Genet. 1997 Nov;17(3):249-50. No abstract available. PMID: 9354775 [PubMed - indexed for MEDLINE]Related articles

Cell-specific expression and regulation of a glucokinase gene locus transgene.

Niswender KD, Postic C, Jetton TL, Bennett BD, Piston DW, Efrat S, Magnuson MA.

J Biol Chem. 1997 Sep 5;272(36):22564-9.PMID: 9278410 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of adenoviral E3 transgenes in beta cells prevents autoimmune diabetes.

von Herrath MG, Efrat S, Oldstone MB, Horwitz MS.

Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9808-13.PMID: 9275207 [PubMed - indexed for MEDLINE]Related articlesFree article

Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen.

Ewald D, Li M, Efrat S, Auer G, Wall RJ, Furth PA, Hennighausen L.

Science. 1996 Sep 6;273(5280):1384-6.PMID: 8703072 [PubMed - indexed for MEDLINE]Related articles

The role of the insulin control element and RIPE3b1 activators in glucose-stimulated transcription of the insulin gene.

Sharma A, Fusco-DeMane D, Henderson E, Efrat S, Stein R.

Mol Endocrinol. 1995 Nov;9(11):1468-76.PMID: 8584024 [PubMed - indexed for MEDLINE]Related articles

Post-transcriptional regulation of human interleukin-2 gene expression at processing of precursor transcripts.

Gerez L, Arad G, Efrat S, Ketzinel M, Kaempfer R.

J Biol Chem. 1995 Aug 18;270(33):19569-75.PMID: 7642643 [PubMed - indexed for MEDLINE]Related articlesFree article

Prolonged survival of pancreatic islet allografts mediated by adenovirus immunoregulatory transgenes.

Efrat S, Fejer G, Brownlee M, Horwitz MS.

Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):6947-51.PMID: 7624350 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence that Rap1 carboxylmethylation is involved in regulated insulin secretion.

Leiser M, Efrat S, Fleischer N.

Endocrinology. 1995 Jun;136(6):2521-30.PMID: 7750474 [PubMed - indexed for MEDLINE]Related articles

Conditional transformation of a pancreatic beta-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene.

Efrat S, Fusco-DeMane D, Lemberg H, al Emran O, Wang X.

Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3576-80.PMID: 7724601 [PubMed - indexed for MEDLINE]Related articlesFree article

Clonal insulinoma cell line that stably maintains correct glucose responsiveness.

Knaack D, Fiore DM, Surana M, Leiser M, Laurance M, Fusco-DeMane D, Hegre OD, Fleischer N, Efrat S.

Diabetes. 1994 Dec;43(12):1413-7.PMID: 7958492 [PubMed - indexed for MEDLINE]Related articles

The pancreatic beta-cell glucose sensor.

Efrat S, Tal M, Lodish HF.

Trends Biochem Sci. 1994 Dec;19(12):535-8. Review.PMID: 7846765 [PubMed - indexed for MEDLINE]Related articles

In situ glucose uptake and glucokinase activity of pancreatic islets in diabetic and obese rodents.

Liang Y, Bonner-Weir S, Wu YJ, Berdanier CD, Berner DK, Efrat S, Matschinsky FM.

J Clin Invest. 1994 Jun;93(6):2473-81.PMID: 8200983 [PubMed - indexed for MEDLINE]Related articlesFree article