PubMed

AKAP 18 alpha and gamma have opposing effects on insulin release in INS-1E cells.

Josefsen K, Lee YC, Thams P, Efendic S, Nielsen JH.

FEBS Lett. 2009 Nov 6. [Epub ahead of print]PMID: 19896945 [PubMed - as supplied by publisher]Related articles

beta-Cell research - A decade of rapid growth.

Ahrén B, Accili D, Boitard C, Efendic S, Henquin JC, Seino S, Steiner DF, Cerasi E.

Diabetes Obes Metab. 2009 Nov;11 Suppl 4:iv-ix. No abstract available. PMID: 19817782 [PubMed - in process]Related articles

Functional and genetic analysis in type 2 diabetes of liver X receptor alleles--a cohort study.

Dahlman I, Nilsson M, Gu HF, Lecoeur C, Efendic S, Ostenson CG, Brismar K, Gustafsson JA, Froguel P, Vaxillaire M, Dahlman-Wright K, Steffensen KR.

BMC Med Genet. 2009 Mar 17;10:27.PMID: 19292929 [PubMed - indexed for MEDLINE]Related articlesFree article

The incretin hormones GIP and GLP-1 in diabetic rats: effects on insulin secretion and small bowel motility.

Edholm T, Cejvan K, Abdel-Halim SM, Efendic S, Schmidt PT, Hellström PM.

Neurogastroenterol Motil. 2009 Mar;21(3):313-21. Epub 2008 Dec 18.PMID: 19126188 [PubMed - indexed for MEDLINE]Related articles

Loci of TCF7L2, HHEX and IDE on chromosome 10q and the susceptibility of their genetic polymorphisms to type 2 diabetes.

Nordman S, Ostenson CG, Efendic S, Gu HF.

Exp Clin Endocrinol Diabetes. 2009 Apr;117(4):186-90. Epub 2008 Dec 3.PMID: 19053027 [PubMed - indexed for MEDLINE]Related articles

Apolipoprotein M promoter polymorphisms alter promoter activity and confer the susceptibility to the development of type 1 diabetes.

Wu X, Niu N, Brismar K, Zhu X, Wang X, Efendic S, Du T, Liu Y, Gu HF, Liu Y.

Clin Biochem. 2009 Jan;42(1-2):17-21. Epub 2008 Oct 30.PMID: 19007767 [PubMed - indexed for MEDLINE]Related articles

Pancreatic beta-cell mass or beta-cell function? That is the question!

Henquin JC, Cerasi E, Efendic S, Steiner DF, Boitard C.

Diabetes Obes Metab. 2008 Nov;10 Suppl 4:1-4. No abstract available. PMID: 18834427 [PubMed - indexed for MEDLINE]Related articles

Estrogen receptor alpha gene variants associate with type 2 diabetes and fasting plasma glucose.

Dahlman I, Vaxillaire M, Nilsson M, Lecoeur C, Gu HF, Cavalcanti-Proença C, Efendic S, Ostenson CG, Brismar K, Charpentier G, Gustafsson JA, Froguel P, Dahlman-Wright K, Steffensen KR.

Pharmacogenet Genomics. 2008 Nov;18(11):967-75.PMID: 18854778 [PubMed - indexed for MEDLINE]Related articles

Lack of an association between GHR exon 3 polymorphism and diabetic nephropathy in the Genetics of Kidneys in Diabetes (GoKinD) population.

Gu HF, Efendic S, Brismar K.

Diabetologia. 2008 Dec;51(12):2333-4. Epub 2008 Sep 5. No abstract available. PMID: 18820897 [PubMed - indexed for MEDLINE]Related articles

Evaluation of genetic association and expression reduction of TRPC1 in the development of diabetic nephropathy.

Zhang D, Freedman BI, Flekac M, Santos E, Hicks PJ, Bowden DW, Efendic S, Brismar K, Gu HF.

Am J Nephrol. 2009;29(3):244-51. Epub 2008 Sep 19.PMID: 18802326 [PubMed - indexed for MEDLINE]Related articlesFree article

The estrogen receptor {alpha}-selective agonist propyl pyrazole triol improves glucose tolerance in ob/ob mice; potential molecular mechanisms.

Lundholm L, Bryzgalova G, Gao H, Portwood N, Fält S, Berndt KD, Dicker A, Galuska D, Zierath JR, Gustafsson JA, Efendic S, Dahlman-Wright K, Khan A.

J Endocrinol. 2008 Nov;199(2):275-86. Epub 2008 Aug 29.PMID: 18757549 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice.

Bryzgalova G, Lundholm L, Portwood N, Gustafsson JA, Khan A, Efendic S, Dahlman-Wright K.

Am J Physiol Endocrinol Metab. 2008 Oct;295(4):E904-12. Epub 2008 Aug 12.PMID: 18697913 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired glucose-stimulated insulin secretion in the GK rat is associated with abnormalities in islet nitric oxide production.

Mosén H, Ostenson CG, Lundquist I, Alm P, Henningsson R, Jimenez-Feltström J, Guenifi A, Efendic S, Salehi A.

Regul Pept. 2008 Nov 29;151(1-3):139-46. Epub 2008 Jul 11.PMID: 18662725 [PubMed - indexed for MEDLINE]Related articles

A single nucleotide polymorphism alters the sequence of SP1 binding site in the adiponectin promoter region and is associated with diabetic nephropathy among type 1 diabetic patients in the Genetics of Kidneys in Diabetes Study.

Zhang D, Ma J, Brismar K, Efendic S, Gu HF.

J Diabetes Complications. 2009 Jul-Aug;23(4):265-72. Epub 2008 Jul 3.PMID: 18599322 [PubMed - indexed for MEDLINE]Related articles

[Reply on new drugs against type 2 diabetes: important to gain experience and knowledge]

Sjöholm A, Agardh CD, Brismar K, Efendic S, Eliasson B, Eriksson JW, Frid A, Groop L, Holmgren J, Ridderstråle M, Smith U.

Lakartidningen. 2008 Apr 23-May 6;105(17-18):1310, 1312. Swedish. No abstract available. PMID: 18561535 [PubMed - indexed for MEDLINE]Related articles

Psychological distress and risk of pre-diabetes and Type 2 diabetes in a prospective study of Swedish middle-aged men and women.

Eriksson AK, Ekbom A, Granath F, Hilding A, Efendic S, Ostenson CG.

Diabet Med. 2008 Jul;25(7):834-42.PMID: 18513304 [PubMed - indexed for MEDLINE]Related articles

Evaluation of the association between the common E469K polymorphism in the ICAM-1 gene and diabetic nephropathy among type 1 diabetic patients in GoKinD population.

Ma J, Zhang D, Brismar K, Efendic S, Gu HF.

BMC Med Genet. 2008 May 27;9:47.PMID: 18505543 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor-binding protein-1 in the prediction and development of type 2 diabetes in middle-aged Swedish men.

Lewitt MS, Hilding A, Ostenson CG, Efendic S, Brismar K, Hall K.

Diabetologia. 2008 Jul;51(7):1135-45. Epub 2008 May 22.PMID: 18496669 [PubMed - indexed for MEDLINE]Related articles

Excessive islet NO generation in type 2 diabetic GK rats coincides with abnormal hormone secretion and is counteracted by GLP-1.

Salehi A, Meidute Abaraviciene S, Jimenez-Feltstrom J, Ostenson CG, Efendic S, Lundquist I.

PLoS One. 2008 May 14;3(5):e2165. Erratum in: PLoS ONE. 2008;3(6). doi: 10.1371/annotation/5efa5d3b-2733-4629-9592-f41e0814ca0b. PLoS ONE. 2008;3(6). doi: 10.1371/annotation/a72da6a5-a71a-4cc9-ae2b-2b95c0ec89b0. PLoS ONE. 2008;3(6). doi: 10.1371/annotation/bea154a4-93b3-4f1a-9948-acbaae12d256. PMID: 18478125 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteins in the insulin-secreting cell line MIN6 bind the imidazoline compound BL11282.

Shafqat J, Ishrat M, Jägerbrink T, Sillard R, Mäeorg U, Efendic S, Berggren PO, Zaitsev SV, Jörnvall H.

FEBS Lett. 2008 May 14;582(11):1613-7. Epub 2008 Apr 15.PMID: 18420036 [PubMed - indexed for MEDLINE]Related articles

Contribution of gluconeogenesis and glycogenolysis to hepatic glucose production in acromegaly before and after pituitary microsurgery.

Höybye C, Chandramouli V, Efendic S, Hulting AL, Landau BR, Schumann WC, Wajngot A.

Horm Metab Res. 2008 Jul;40(7):498-501. Epub 2008 Mar 31.PMID: 18393170 [PubMed - indexed for MEDLINE]Related articles

GLP-1 suppresses gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome.

Hellström PM, Näslund E, Edholm T, Schmidt PT, Kristensen J, Theodorsson E, Holst JJ, Efendic S.

Neurogastroenterol Motil. 2008 Jun;20(6):649-59. Epub 2008 Feb 19.PMID: 18298441 [PubMed - indexed for MEDLINE]Related articles

Insulin glargine improves glycaemic control after coronary surgery in patients with diabetes or pre-diabetes.

Hagelberg A, Ivert T, Efendić S, Ohrvik J, Anderson RE.

Scand Cardiovasc J. 2008 Feb;42(1):71-6.PMID: 18273733 [PubMed - indexed for MEDLINE]Related articles

Postprandial paradoxical IGFBP-1 response in obese patients with Type 2 diabetes.

Lehtihet M, Efendic S, Brismar K.

Clin Sci (Lond). 2008 Sep;115(5):167-74.PMID: 18208402 [PubMed - indexed for MEDLINE]Related articles

Pathophysiology and treatment of patients with type 2 diabetes exhibiting failure to oral drugs.

Efendic S, Alvarsson M, Brismar K, Wagner H.

Acta Physiol (Oxf). 2008 Jan;192(1):117-25. Review.PMID: 18171434 [PubMed - indexed for MEDLINE]Related articles

Distribution of neuropeptide Y Leu7Pro polymorphism in patients with type 1 diabetes and diabetic nephropathy among Swedish and American populations.

Ma J, Nordman S, Möllsten A, Falhammar H, Brismar K, Dahlquist G, Efendic S, Gu HF.

Eur J Endocrinol. 2007 Nov;157(5):641-5.PMID: 17984244 [PubMed - indexed for MEDLINE]Related articlesFree article

Arachidonic acid signaling is involved in the mechanism of imidazoline-induced KATP channel-independent stimulation of insulin secretion.

Sharoyko VV, Zaitseva II, Leibiger B, Efendić S, Berggren PO, Zaitsev SV.

Cell Mol Life Sci. 2007 Nov;64(22):2985-93.PMID: 17922229 [PubMed - indexed for MEDLINE]Related articles

Islet gene expression and function in type 2 diabetes; studies in the Goto-Kakizaki rat and humans.

Ostenson CG, Efendic S.

Diabetes Obes Metab. 2007 Nov;9 Suppl 2:180-6. Review.PMID: 17919192 [PubMed - indexed for MEDLINE]Related articles

Of mighty mice and diabetic men: animal models of islet dysfunction.

Efendic S, Boitard C, Ferrannini E, Henquin JC, Steiner DF, Cerasi E.

Diabetes Obes Metab. 2007 Nov;9 Suppl 2:1-4. No abstract available. PMID: 17919172 [PubMed - indexed for MEDLINE]Related articles

Genetic variation of the adenylyl cyclase 3 (AC3) locus and its influence on type 2 diabetes and obesity susceptibility in Swedish men.

Nordman S, Abulaiti A, Hilding A, Långberg EC, Humphreys K, Ostenson CG, Efendic S, Gu HF.

Int J Obes (Lond). 2008 Mar;32(3):407-12. Epub 2007 Sep 25.PMID: 17895882 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in receptor protein tyrosine phosphatase sigma is associated with type 2 diabetes in Swedish Caucasians.

Långberg EC, Gu HF, Nordman S, Efendic S, Ostenson CG.

Eur J Endocrinol. 2007 Oct;157(4):459-64.PMID: 17893260 [PubMed - indexed for MEDLINE]Related articlesFree article

GHR exon 3 polymorphism: association with type 2 diabetes mellitus and metabolic disorder.

Strawbridge RJ, Kärvestedt L, Li C, Efendic S, Ostenson CG, Gu HF, Brismar K.

Growth Horm IGF Res. 2007 Oct;17(5):392-8. Epub 2007 May 29.PMID: 17537658 [PubMed - indexed for MEDLINE]Related articles

Ca2+-secretion coupling is impaired in diabetic Goto Kakizaki rats.

Rose T, Efendic S, Rupnik M.

J Gen Physiol. 2007 Jun;129(6):493-508.PMID: 17535961 [PubMed - indexed for MEDLINE]Related articlesFree article

Socio-economic position at three points in life in association with type 2 diabetes and impaired glucose tolerance in middle-aged Swedish men and women.

Agardh EE, Ahlbom A, Andersson T, Efendic S, Grill V, Hallqvist J, Ostenson CG.

Int J Epidemiol. 2007 Feb;36(1):84-92.PMID: 17510076 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential protein expression in pancreatic islets after treatment with an imidazoline compound.

Jägerbrink T, Lexander H, Palmberg C, Shafqat J, Sharoyko V, Berggren PO, Efendic S, Zaitsev S, Jörnvall H.

Cell Mol Life Sci. 2007 May;64(10):1310-6.PMID: 17458497 [PubMed - indexed for MEDLINE]Related articles

Diabetic type II Goto-Kakizaki rats show progressively decreasing exploratory activity and learning impairments in fixed and progressive ratios of a lever-press task.

Moreira T, Malec E, Ostenson CG, Efendic S, Liljequist S.

Behav Brain Res. 2007 Jun 4;180(1):28-41. Epub 2007 Feb 25.PMID: 17408764 [PubMed - indexed for MEDLINE]Related articles

The BioBreeding rat diabetes model is infected with Ljungan virus.

Niklasson B, Hultman T, Kallies R, Niedrig M, Nilsson R, Berggren PO, Juntti-Berggren L, Efendic S, Lernmark A, Klitz W.

Diabetologia. 2007 Jul;50(7):1559-60. Epub 2007 Apr 4. No abstract available. Erratum in: Diabetologia. 2007 Oct;50(10):2227. PMID: 17406852 [PubMed - indexed for MEDLINE]Related articles

Reduced HO-1 protein expression is associated with more severe neurodegeneration after transient ischemia induced by cortical compression in diabetic Goto-Kakizaki rats.

Moreira TJ, Cebere A, Cebers G, Ostenson CG, Efendic S, Liljequist S.

J Cereb Blood Flow Metab. 2007 Oct;27(10):1710-23. Epub 2007 Apr 4.PMID: 17406657 [PubMed - indexed for MEDLINE]Related articles

Activity of the plant peptide aglycin in mammalian systems.

Dun XP, Wang JH, Chen L, Lu J, Li FF, Zhao YY, Cederlund E, Bryzgalova G, Efendic S, Jörnvall H, Chen ZW, Bergman T.

FEBS J. 2007 Feb;274(3):751-9.PMID: 17288555 [PubMed - indexed for MEDLINE]Related articles

Genetic association analysis of the adiponectin polymorphisms in type 1 diabetes with and without diabetic nephropathy.

Ma J, Möllsten A, Falhammar H, Brismar K, Dahlquist G, Efendic S, Gu HF.

J Diabetes Complications. 2007 Jan-Feb;21(1):28-33.PMID: 17189871 [PubMed - indexed for MEDLINE]Related articles

Diabetic Goto-Kakizaki rats display pronounced hyperglycemia and longer-lasting cognitive impairments following ischemia induced by cortical compression.

Moreira T, Cebers G, Pickering C, Ostenson CG, Efendic S, Liljequist S.

Neuroscience. 2007 Feb 23;144(4):1169-85. Epub 2006 Dec 18.PMID: 17175109 [PubMed - indexed for MEDLINE]Related articles

Effects of glucagon-like peptide-1-(7-36)-amide on pancreatic islet and intestinal blood perfusion in Wistar rats and diabetic GK rats.

Svensson AM, Ostenson CG, Efendic S, Jansson L.

Clin Sci (Lond). 2007 Jun;112(6):345-51.PMID: 17087662 [PubMed - indexed for MEDLINE]Related articles

Postprandial hyperglycaemia and vascular damage--the benefits of acarbose.

Båvenholm PN, Efendic S.

Diab Vasc Dis Res. 2006 Sep;3(2):72-9. Review.PMID: 17058626 [PubMed - indexed for MEDLINE]Related articles

Genetic influences of the intercellular adhesion molecule 1 (ICAM-1) gene polymorphisms in development of Type 1 diabetes and diabetic nephropathy.

Ma J, Möllsten A, Prázny M, Falhammar H, Brismar K, Dahlquist G, Efendic S, Gu HF.

Diabet Med. 2006 Oct;23(10):1093-9.PMID: 16978373 [PubMed - indexed for MEDLINE]Related articlesFree article

The impact of family history of diabetes and lifestyle factors on abnormal glucose regulation in middle-aged Swedish men and women.

Hilding A, Eriksson AK, Agardh EE, Grill V, Ahlbom A, Efendic S, Ostenson CG.

Diabetologia. 2006 Nov;49(11):2589-98. Epub 2006 Sep 13.PMID: 16969647 [PubMed - indexed for MEDLINE]Related articles

RX871024 reduces NO production but does not protect against pancreatic beta-cell death induced by proinflammatory cytokines.

Zaitseva II, Sharoyko V, Størling J, Efendic S, Guerin C, Mandrup-Poulsen T, Nicotera P, Berggren PO, Zaitsev SV.

Biochem Biophys Res Commun. 2006 Sep 8;347(4):1121-8. Epub 2006 Jul 14.PMID: 16870144 [PubMed - indexed for MEDLINE]Related articles

Combined treatment with exercise training and acarbose improves metabolic control and cardiovascular risk factor profile in subjects with mild type 2 diabetes.

Wagner H, Degerblad M, Thorell A, Nygren J, Ståhle A, Kuhl J, Brismar TB, Ohrvik J, Efendic S, Båvenholm PN.

Diabetes Care. 2006 Jul;29(7):1471-7.PMID: 16801564 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced endothelium-dependent vasodilatation by dual endothelin receptor blockade in individuals with insulin resistance.

Shemyakin A, Böhm F, Wagner H, Efendic S, Båvenholm P, Pernow J.

J Cardiovasc Pharmacol. 2006 Mar;47(3):385-90.PMID: 16633080 [PubMed - indexed for MEDLINE]Related articles

Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: a possible mechanism is through direct regulation of signal transducer and activator of transcription 3.

Gao H, Bryzgalova G, Hedman E, Khan A, Efendic S, Gustafsson JA, Dahlman-Wright K.

Mol Endocrinol. 2006 Jun;20(6):1287-99. Epub 2006 Apr 20.PMID: 16627594 [PubMed - indexed for MEDLINE]Related articlesFree article

Exendin-4 treatment improves metabolic control after rat islet transplantation to athymic mice with streptozotocin-induced diabetes.

Sharma A, Sörenby A, Wernerson A, Efendic S, Kumagai-Braesch M, Tibell A.

Diabetologia. 2006 Jun;49(6):1247-53. Epub 2006 Apr 12.PMID: 16609877 [PubMed - indexed for MEDLINE]Related articles