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    Results: 28

    1.

    Effects of Insulin on the Metabolic Control of Hepatic Gluconeogenesis in vivo.

    Edgerton DS, Ramnanan CJ, Grueter CA, Johnson KM, Lautz M, Neal DW, Williams PE, Cherrington AD.

    Diabetes. 2009 Sep 15. [Epub ahead of print]PMID: 19755527 [PubMed - as supplied by publisher]Related articles

    2.

    Current strategies for the inhibition of hepatic glucose production in type 2 diabetes.

    Edgerton DS, Johnson KM, Cherrington AD.

    Front Biosci. 2009 Jan 1;14:1169-81. Review.PMID: 19273123 [PubMed - indexed for MEDLINE]Related articles

    3.

    Inhaled insulin is associated with prolonged enhancement of glucose disposal in muscle and liver in the canine.

    Edgerton DS, Cherrington AD, Neal DW, Scott M, Lautz M, Brown N, Petro J, Hobbs CH, Leach C, Del Parigi A, Strack TR.

    J Pharmacol Exp Ther. 2009 Mar;328(3):970-5. Epub 2008 Dec 19.PMID: 19098161 [PubMed - indexed for MEDLINE]Related articles

    4.

    Inhibition of dipeptidyl peptidase-4 by vildagliptin during glucagon-like Peptide 1 infusion increases liver glucose uptake in the conscious dog.

    Edgerton DS, Johnson KM, Neal DW, Scott M, Hobbs CH, Zhang X, Duttaroy A, Cherrington AD.

    Diabetes. 2009 Jan;58(1):243-9. Epub 2008 Oct 7.PMID: 18840785 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Intraportally delivered GLP-1, in the presence of hyperglycemia induced via peripheral glucose infusion, does not change whole body glucose utilization.

    Johnson KM, Edgerton DS, Rodewald T, Scott M, Farmer B, Neal D, Cherrington AD.

    Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E380-4. Epub 2007 Dec 4.PMID: 18056788 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Effects of the nitric oxide donor SIN-1 on net hepatic glucose uptake in the conscious dog.

    An Z, DiCostanzo CA, Moore MC, Edgerton DS, Dardevet DP, Neal DW, Cherrington AD.

    Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E300-6. Epub 2007 Nov 20.PMID: 18029444 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Insulin action on the liver in vivo.

    Cherrington AD, Moore MC, Sindelar DK, Edgerton DS.

    Biochem Soc Trans. 2007 Nov;35(Pt 5):1171-4. Review.PMID: 17956305 [PubMed - indexed for MEDLINE]Related articles

    8.

    Intraportal GLP-1 infusion increases nonhepatic glucose utilization without changing pancreatic hormone levels.

    Johnson KM, Edgerton DS, Rodewald T, Scott M, Farmer B, Neal D, Cherrington AD.

    Am J Physiol Endocrinol Metab. 2007 Oct;293(4):E1085-91. Epub 2007 Aug 7.PMID: 17684104 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Triglyceride uptake and lipoprotein lipase-generated fatty acid spillover in the splanchnic bed of dogs.

    Nelson RH, Edgerton DS, Basu R, Roesner JC, Cherrington AD, Miles JM.

    Diabetes. 2007 Jul;56(7):1850-5. Epub 2007 Apr 6.PMID: 17416801 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    A novel glucagon receptor antagonist, NNC 25-0926, blunts hepatic glucose production in the conscious dog.

    Rivera N, Everett-Grueter CA, Edgerton DS, Rodewald T, Neal DW, Nishimura E, Larsen MO, Jacobsen LO, Kristensen K, Brand CL, Cherrington AD.

    J Pharmacol Exp Ther. 2007 May;321(2):743-52. Epub 2007 Feb 16.PMID: 17308040 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Inhalation of human insulin (exubera) augments the efficiency of muscle glucose uptake in vivo.

    Edgerton DS, Cherrington AD, Williams P, Neal DW, Scott M, Bowen L, Wilson W, Hobbs CH, Leach C, Kuo MC, Strack TR.

    Diabetes. 2006 Dec;55(12):3604-10.PMID: 17130510 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Splanchnic cortisol production in dogs occurs primarily in the liver: evidence for substantial hepatic specific 11beta hydroxysteroid dehydrogenase type 1 activity.

    Basu R, Edgerton DS, Singh RJ, Cherrington A, Rizza RA.

    Diabetes. 2006 Nov;55(11):3013-9.PMID: 17065337 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Inhalation of human insulin is associated with improved insulin action compared with subcutaneous injection and endogenous secretion in dogs.

    Edgerton DS, Stettler KM, Neal DW, Scott M, Bowen L, Wilson W, Hobbs CH, Leach C, Strack TR, Cherrington AD.

    J Pharmacol Exp Ther. 2006 Dec;319(3):1258-64. Epub 2006 Sep 8.PMID: 16963622 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Selective antagonism of the hepatic glucocorticoid receptor reduces hepatic glucose production.

    Edgerton DS, Jacobson PB, Opgenorth TJ, Zinker B, Beno D, von Geldern T, Ohman L, Scott M, Neal D, Cherrington AD.

    Metabolism. 2006 Sep;55(9):1255-62.PMID: 16919547 [PubMed - indexed for MEDLINE]Related articles

    15.

    The effect of an acute elevation of NEFA concentrations on glucagon-stimulated hepatic glucose output.

    Everett-Grueter C, Edgerton DS, Donahue EP, Vaughan S, Chu CA, Sindelar DK, Cherrington AD.

    Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E449-59. Epub 2006 Apr 11.PMID: 16608886 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Insulin's direct effects on the liver dominate the control of hepatic glucose production.

    Edgerton DS, Lautz M, Scott M, Everett CA, Stettler KM, Neal DW, Chu CA, Cherrington AD.

    J Clin Invest. 2006 Feb;116(2):521-7.PMID: 16453026 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Islet auto-transplantation into an omental or splenic site results in a normal beta cell but abnormal alpha cell response to mild non-insulin-induced hypoglycemia.

    Gustavson SM, Rajotte RV, Hunkeler D, Lakey JR, Edgerton DS, Neal DW, Snead WL, Penaloza AR, Cherrington AD.

    Am J Transplant. 2005 Oct;5(10):2368-77.PMID: 16162184 [PubMed - indexed for MEDLINE]Related articles

    18.

    Inhalation of insulin (Exubera) is associated with augmented disposal of portally infused glucose in dogs.

    Edgerton DS, Neal DW, Scott M, Bowen L, Wilson W, Hobbs CH, Leach C, Sivakumaran S, Strack TR, Cherrington AD.

    Diabetes. 2005 Apr;54(4):1164-70.PMID: 15793257 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes.

    Jacobson PB, von Geldern TW, Ohman L, Osterland M, Wang J, Zinker B, Wilcox D, Nguyen PT, Mika A, Fung S, Fey T, Goos-Nilsson A, Grynfarb M, Barkhem T, Marsh K, Beno DW, Nga-Nguyen B, Kym PR, Link JT, Tu N, Edgerton DS, Cherrington A, Efendic S, Lane BC, Opgenorth TJ.

    J Pharmacol Exp Ther. 2005 Jul;314(1):191-200. Epub 2005 Mar 22.PMID: 15784656 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Vagal cooling and concomitant portal norepinephrine infusion do not reduce net hepatic glucose uptake in conscious dogs.

    Cardin S, Pagliassotti MJ, Moore MC, Edgerton DS, Lautz M, Farmer B, Neal DW, Cherrington AD.

    Am J Physiol Regul Integr Comp Physiol. 2004 Oct;287(4):R742-8. Epub 2004 May 27.PMID: 15166005 [PubMed - indexed for MEDLINE]Related articles

    21.

    Inhalation of insulin in dogs: assessment of insulin levels and comparison to subcutaneous injection.

    Cherrington AD, Neal DW, Edgerton DS, Glass D, Bowen L, Hobbs CH, Leach C, Rosskamp R, Strack TR.

    Diabetes. 2004 Apr;53(4):877-81.PMID: 15047601 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    Effects of hyperglycemia on hepatic gluconeogenic flux during glycogen phosphorylase inhibition in the conscious dog.

    Edgerton DS, Cardin S, Neal D, Farmer B, Lautz M, Pan C, Cherrington AD.

    Am J Physiol Endocrinol Metab. 2004 Apr;286(4):E510-22. Epub 2003 Nov 25.PMID: 14644767 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    Unlike mice, dogs exhibit effective glucoregulation during low-dose portal and peripheral glucose infusion.

    Moore MC, Cardin S, Edgerton DS, Farmer B, Neal DW, Lautz M, Cherrington AD.

    Am J Physiol Endocrinol Metab. 2004 Feb;286(2):E226-33. Epub 2003 Sep 30.PMID: 14519598 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Effects of insulin deficiency or excess on hepatic gluconeogenic flux during glycogenolytic inhibition in the conscious dog.

    Edgerton DS, Cardin S, Pan C, Neal D, Farmer B, Converse M, Cherrington AD.

    Diabetes. 2002 Nov;51(11):3151-62.PMID: 12401705 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Selective tonic inhibition of G-6-Pase catalytic subunit, but not G-6-P transporter, gene expression by insulin in vivo.

    Hornbuckle LA, Edgerton DS, Ayala JE, Svitek CA, Oeser JK, Neal DW, Cardin S, Cherrington AD, O'Brien RM.

    Am J Physiol Endocrinol Metab. 2001 Oct;281(4):E713-25.PMID: 11551847 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    Small increases in insulin inhibit hepatic glucose production solely caused by an effect on glycogen metabolism.

    Edgerton DS, Cardin S, Emshwiller M, Neal D, Chandramouli V, Schumann WC, Landau BR, Rossetti L, Cherrington AD.

    Diabetes. 2001 Aug;50(8):1872-82.PMID: 11473051 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.

    Effect of vagal cooling on the counterregulatory response to hypoglycemia induced by a low dose of insulin in the conscious dog.

    Cardin S, Jackson PA, Edgerton DS, Neal DW, Coffey CS, Cherrington AD.

    Diabetes. 2001 Mar;50(3):558-64.PMID: 11246875 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    Portal glucose infusion increases hepatic glycogen deposition in conscious unrestrained rats.

    Cardin S, Emshwiller M, Jackson PA, Snead WL, Hastings J, Edgerton DS, Cherrington AD.

    J Appl Physiol. 1999 Oct;87(4):1470-5.PMID: 10517780 [PubMed - indexed for MEDLINE]Related articlesFree article

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