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    Results: 41

    1.

    Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis.

    Donelan MJ, Morfini G, Julyan R, Sommers S, Hays L, Kajio H, Briaud I, Easom RA, Molkentin JD, Brady ST, Rhodes CJ.

    J Biol Chem. 2002 Jul 5;277(27):24232-42. Epub 2002 Apr 26.PMID: 11978799 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1.

    Lawrence MC, Bhatt HS, Easom RA.

    Diabetes. 2002 Mar;51(3):691-8.PMID: 11872668 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Regulation of insulin gene transcription by a Ca(2+)-responsive pathway involving calcineurin and nuclear factor of activated T cells.

    Lawrence MC, Bhatt HS, Watterson JM, Easom RA.

    Mol Endocrinol. 2001 Oct;15(10):1758-67.PMID: 11579208 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Dependence of insulin secretion from permeabilized pancreatic beta-cells on the activation of Ca(2+)/calmodulin-dependent protein kinase II. A re-evaluation of inhibitor studies.

    Bhatt HS, Conner BP, Prasanna G, Yorio T, Easom RA.

    Biochem Pharmacol. 2000 Dec 1;60(11):1655-63.PMID: 11077048 [PubMed - indexed for MEDLINE]Related articles

    5.

    Beta-granule transport and exocytosis.

    Easom RA.

    Semin Cell Dev Biol. 2000 Aug;11(4):253-66. Review.PMID: 10966859 [PubMed - indexed for MEDLINE]Related articles

    6.

    CaM kinase II: a protein kinase with extraordinary talents germane to insulin exocytosis.

    Easom RA.

    Diabetes. 1999 Apr;48(4):675-84. Review.PMID: 10102681 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Site-specific phosphorylation of synapsin I by Ca2+/calmodulin-dependent protein kinase II in pancreatic betaTC3 cells: synapsin I is not associated with insulin secretory granules.

    Krueger KA, Ings EI, Brun AM, Landt M, Easom RA.

    Diabetes. 1999 Mar;48(3):499-506.PMID: 10078549 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Dephosphorylation and deactivation of Ca2+/calmodulin-dependent protein kinase II in betaTC3-cells is mediated by Mg2+- and okadaic-acid-sensitive protein phosphatases.

    Easom RA, Tarpley JL, Filler NR, Bhatt H.

    Biochem J. 1998 Jan 15;329 ( Pt 2):283-8.PMID: 9425110 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Calcium-stimulated phosphorylation of MAP-2 in pancreatic betaTC3-cells is mediated by Ca2+/calmodulin-dependent kinase II.

    Krueger KA, Bhatt H, Landt M, Easom RA.

    J Biol Chem. 1997 Oct 24;272(43):27464-9.PMID: 9341200 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Correlation of the activation of Ca2+/calmodulin-dependent protein kinase II with the initiation of insulin secretion from perifused pancreatic islets.

    Easom RA, Filler NR, Ings EM, Tarpley J, Landt M.

    Endocrinology. 1997 Jun;138(6):2359-64.PMID: 9165023 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Muscarinic activation of Ca2+/calmodulin-dependent protein kinase II in pancreatic islets. Temporal dissociation of kinase activation and insulin secretion.

    Babb EL, Tarpley J, Landt M, Easom RA.

    Biochem J. 1996 Jul 1;317 ( Pt 1):167-72.PMID: 8694759 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Gramicidin D is a potent insulin secretagogue: dependence on extracellular calcium influx.

    Dibas AI, Yorio T, Easom RA.

    Biochem Biophys Res Commun. 1995 Jul 17;212(2):449-54.PMID: 7542876 [PubMed - indexed for MEDLINE]Related articles

    13.

    Glucose activates the multifunctional Ca2+/calmodulin-dependent protein kinase II in isolated rat pancreatic islets.

    Wenham RM, Landt M, Easom RA.

    J Biol Chem. 1994 Feb 18;269(7):4947-52.PMID: 8106469 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    The dependence of electrophoretic and spectroscopic properties of the pyruvate dehydrogenase complex on mono- and divalent ions.

    Pawełczyk T, Easom RA, Olson MS.

    Acta Biochim Pol. 1994;41(1):63-72.PMID: 8030376 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Regulation of paracellular permeability in Caco-2 cell monolayers by protein kinase C.

    Stenson WF, Easom RA, Riehl TE, Turk J.

    Am J Physiol. 1993 Nov;265(5 Pt 1):G955-62.PMID: 8238525 [PubMed - indexed for MEDLINE]Related articles

    16.

    Inhibition of insulin secretion by KN-62, a specific inhibitor of the multifunctional Ca2+/calmodulin-dependent protein kinase II.

    Wenham RM, Landt M, Walters SM, Hidaka H, Easom RA.

    Biochem Biophys Res Commun. 1992 Nov 30;189(1):128-33.PMID: 1333187 [PubMed - indexed for MEDLINE]Related articles

    17.

    Effect of ionic strength and pH on the activity of pyruvate dehydrogenase complex from pig kidney cortex.

    Pawelczyk T, Easom RA, Olson MS.

    Arch Biochem Biophys. 1992 Apr;294(1):44-9.PMID: 1550359 [PubMed - indexed for MEDLINE]Related articles

    18.

    Parallel effects of arachidonic acid on insulin secretion, calmodulin-dependent protein kinase activity and protein kinase C activity in pancreatic islets.

    Landt M, Easom RA, Colca JR, Wolf BA, Turk J, Mills LA, McDaniel ML.

    Cell Calcium. 1992 Mar;13(3):163-72.PMID: 1315620 [PubMed - indexed for MEDLINE]Related articles

    19.

    Diacylglycerol accumulation and microvascular abnormalities induced by elevated glucose levels.

    Wolf BA, Williamson JR, Easom RA, Chang K, Sherman WR, Turk J.

    J Clin Invest. 1991 Jan;87(1):31-8.PMID: 1985103 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Effects of insulin secretagogues on protein kinase C-catalyzed phosphorylation of an endogenous substrate in isolated pancreatic islets.

    Easom RA, Landt M, Colca JR, Hughes JH, Turk J, McDaniel M.

    J Biol Chem. 1990 Sep 5;265(25):14938-46.PMID: 2203765 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Interleukin 1 inhibits insulin secretion from isolated rat pancreatic islets by a process that requires gene transcription and mRNA translation.

    Hughes JH, Colca JR, Easom RA, Turk J, McDaniel ML.

    J Clin Invest. 1990 Sep;86(3):856-63.PMID: 2203826 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    Evidence for a role of microfilaments in insulin release from purified beta-cells.

    Wang JL, Easom RA, Hughes JH, McDaniel ML.

    Biochem Biophys Res Commun. 1990 Aug 31;171(1):424-30.PMID: 2168179 [PubMed - indexed for MEDLINE]Related articles

    23.

    Interleukin-1 induces rapid and transient expression of the c-fos proto-oncogene in isolated pancreatic islets and in purified beta-cells.

    Hughes JH, Watson MA, Easom RA, Turk J, McDaniel ML.

    FEBS Lett. 1990 Jun 18;266(1-2):33-6.PMID: 2114318 [PubMed - indexed for MEDLINE]Related articles

    24.

    Diacylglycerol synthesis de novo from glucose by pancreatic islets isolated from rats and humans.

    Wolf BA, Easom RA, McDaniel ML, Turk J.

    J Clin Invest. 1990 Feb;85(2):482-90.PMID: 2405021 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Comparison of effects of phorbol esters and glucose on protein kinase C activation and insulin secretion in pancreatic islets.

    Easom RA, Hughes JH, Landt M, Wolf BA, Turk J, McDaniel ML.

    Biochem J. 1989 Nov 15;264(1):27-33.PMID: 2690823 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    Interleukin 1-induced prostaglandin E2 accumulation by isolated pancreatic islets.

    Hughes JH, Easom RA, Wolf BA, Turk J, McDaniel ML.

    Diabetes. 1989 Oct;38(10):1251-7.PMID: 2507377 [PubMed - indexed for MEDLINE]Related articles

    27.

    The sieving of spheres during agarose gel electrophoresis: quantitation and modeling.

    Griess GA, Moreno ET, Easom RA, Serwer P.

    Biopolymers. 1989 Aug;28(8):1475-84.PMID: 2752101 [PubMed - indexed for MEDLINE]Related articles

    28.

    Secretagogue-induced diacylglycerol accumulation in isolated pancreatic islets. Mass spectrometric characterization of the fatty acyl content indicates multiple mechanisms of generation.

    Wolf BA, Easom RA, Hughes JH, McDaniel ML, Turk J.

    Biochemistry. 1989 May 16;28(10):4291-301.PMID: 2504278 [PubMed - indexed for MEDLINE]Related articles

    29.

    Arachidonic acid metabolism in isolated pancreatic islets. V. The enantiomeric composition of 12-hydroxy-5,8,10,14-eicosatetraenoic acid indicates synthesis by a 12-lipoxygenase rather than a monooxygenase.

    Turk J, Wolf BA, Easom RA, Hughes JH, McDaniel ML.

    Biochim Biophys Acta. 1989 Jan 23;1001(1):16-24.PMID: 2492199 [PubMed - indexed for MEDLINE]Related articles

    30.

    Size determination of multienzyme complexes using two-dimensional agarose gel electrophoresis.

    Easom RA, DeBuysere MS, Olson MS, Serwer P.

    Proteins. 1989;5(3):224-32.PMID: 2506543 [PubMed - indexed for MEDLINE]Related articles

    31.

    Quantitative stereochemical analysis of subnanogram amounts of 12-hydroxy-(5,8,10,14)-eicosatetraenoic acid by sequential chiral phase liquid chromatography and stable isotope dilution mass spectrometry.

    Turk J, Stump WT, Wolf BA, Easom RA, McDaniel ML.

    Anal Biochem. 1988 Nov 1;174(2):580-8.PMID: 3071179 [PubMed - indexed for MEDLINE]Related articles

    32.

    Descriptive and mechanistic considerations of interleukin 1 and insulin secretion.

    McDaniel ML, Hughes JH, Wolf BA, Easom RA, Turk JW.

    Diabetes. 1988 Oct;37(10):1311-5.PMID: 3046964 [PubMed - indexed for MEDLINE]Related articles

    33.

    The effects of various anions and cations on the regulation of pyruvate dehydrogenase complex activity from pig kidney cortex.

    Pawelczyk T, Easom RA, Olson MS.

    Biochem J. 1988 Aug 1;253(3):819-25.PMID: 3178738 [PubMed - indexed for MEDLINE]Related articlesFree article

    34.

    Arachidonic acid metabolism and insulin secretion by isolated human pancreatic islets.

    Turk J, Hughes JH, Easom RA, Wolf BA, Scharp DW, Lacy PE, McDaniel ML.

    Diabetes. 1988 Jul;37(7):992-6.PMID: 3133262 [PubMed - indexed for MEDLINE]Related articles

    35.

    Role of reversible phosphorylation in mediating changes in the activity of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase during pregnancy and lactation in the rat.

    Easom RA, Zammit VA.

    Biochem J. 1987 Dec 15;248(3):993-6.PMID: 3435498 [PubMed - indexed for MEDLINE]Related articlesFree article

    36.

    Regulation of hepatic HMG-CoA reductase in vivo by reversible phosphorylation.

    Zammit VA, Easom RA.

    Biochim Biophys Acta. 1987 Feb 18;927(2):223-8. Review. No abstract available. PMID: 3545301 [PubMed - indexed for MEDLINE]Related articles

    37.

    Acute effects of starvation and treatment of rats with anti-insulin serum, glucagon and catecholamines on the state of phosphorylation of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase in vivo.

    Easom RA, Zammit VA.

    Biochem J. 1987 Jan 1;241(1):183-8. Erratum in: Biochem J 1987 May 1;243(3):871. PMID: 2882748 [PubMed - indexed for MEDLINE]Related articlesFree article

    38.

    Effects of diabetes on the expressed and total activities of 3-hydroxy-3-methylglutaryl-CoA reductase in rat liver in vivo. Reversal by insulin treatment.

    Easom RA, Zammit VA.

    Biochem J. 1985 Sep 15;230(3):747-52.PMID: 3904728 [PubMed - indexed for MEDLINE]Related articlesFree article

    39.

    A cold-clamping technique for the rapid sampling of rat liver for studies on enzymes in separate cell fractions. Suitability for the study of enzymes regulated by reversible phosphorylation-dephosphorylation.

    Easom RA, Zammit VA.

    Biochem J. 1984 Jun 15;220(3):733-8.PMID: 6466299 [PubMed - indexed for MEDLINE]Related articlesFree article

    40.

    Diurnal changes in the fraction of 3-hydroxy-3-methylglutaryl-CoA reductase in the active form in rat liver microsomal fractions.

    Easom RA, Zammit VA.

    Biochem J. 1984 Jun 15;220(3):739-45.PMID: 6087794 [PubMed - indexed for MEDLINE]Related articlesFree article

    41.

    Citrate synthase of Escherichia coli. Characterisation of the enzyme from a plasmid-cloned gene and amplification of the intracellular levels.

    Robinson MS, Easom RA, Danson MJ, Weitzman PD.

    FEBS Lett. 1983 Apr 5;154(1):51-4. No abstract available. PMID: 6339275 [PubMed - indexed for MEDLINE]Related articles

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