PubMed

Cytokine gene polymorphisms in heavy drinkers with and without decompensated liver disease: a case-control study.

Gleeson D, Bradley MP, Jones J, Peck RJ, Bond SK, Teare MD, Duff GW.

Am J Gastroenterol. 2008 Dec;103(12):3039-46.PMID: 19086955 [PubMed - indexed for MEDLINE]Related articles

Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis.

Nile CJ, Read RC, Akil M, Duff GW, Wilson AG.

Arthritis Rheum. 2008 Sep;58(9):2686-93.PMID: 18759290 [PubMed - in process]Related articlesFree article

IL1B gene promoter haplotype pairs predict clinical levels of interleukin-1beta and C-reactive protein.

Rogus J, Beck JD, Offenbacher S, Huttner K, Iacoviello L, Latella MC, de Gaetano M, Wang HY, Kornman KS, Duff GW.

Hum Genet. 2008 May;123(4):387-98. Epub 2008 Mar 28.PMID: 18369665 [PubMed - indexed for MEDLINE]Related articles

Association analysis of the skin barrier gene cystatin A at the PSORS5 locus in psoriatic patients: evidence for interaction between PSORS1 and PSORS5.

Vasilopoulos Y, Walters K, Cork MJ, Duff GW, Sagoo GS, Tazi-Ahnini R.

Eur J Hum Genet. 2008 Aug;16(8):1002-9. Epub 2008 Mar 26.PMID: 18364739 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of genetics on disease susceptibility and progression.

Duff GW.

Nutr Rev. 2007 Dec;65(12 Pt 2):S177-81. Review.PMID: 18240545 [PubMed - indexed for MEDLINE]Related articles

A nonsynonymous substitution of cystatin A, a cysteine protease inhibitor of house dust mite protease, leads to decreased mRNA stability and shows a significant association with atopic dermatitis.

Vasilopoulos Y, Cork MJ, Teare D, Marinou I, Ward SJ, Duff GW, Tazi-Ahnini R.

Allergy. 2007 May;62(5):514-9.PMID: 17441792 [PubMed - indexed for MEDLINE]Related articles

New perspectives on epidermal barrier dysfunction in atopic dermatitis: gene-environment interactions.

Cork MJ, Robinson DA, Vasilopoulos Y, Ferguson A, Moustafa M, MacGowan A, Duff GW, Ward SJ, Tazi-Ahnini R.

J Allergy Clin Immunol. 2006 Jul;118(1):3-21; quiz 22-3. Epub 2006 Jun 9. Review.PMID: 16815133 [PubMed - indexed for MEDLINE]Related articles

The future of living well to 100.

Duff GW, Libby P, Ordovas JM, Reilly PR.

Am J Clin Nutr. 2006 Feb;83(2):488S-490S. Review. No abstract available. PMID: 16470018 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for genetic variation as a factor in maintaining health.

Duff GW.

Am J Clin Nutr. 2006 Feb;83(2):431S-435S. Review.PMID: 16470008 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-1: a key inflammatory mediator in psoriasis?

Mee JB, Cork MJ, di Giovine FS, Duff GW, Groves RW.

Cytokine. 2006 Jan 21;33(2):72-8. Epub 2006 Feb 3.PMID: 16460958 [PubMed - indexed for MEDLINE]Related articles

Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context.

Chen H, Wilkins LM, Aziz N, Cannings C, Wyllie DH, Bingle C, Rogus J, Beck JD, Offenbacher S, Cork MJ, Rafie-Kolpin M, Hsieh CM, Kornman KS, Duff GW.

Hum Mol Genet. 2006 Feb 15;15(4):519-29. Epub 2006 Jan 6.PMID: 16399797 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence of a pharmacogenomic response to interleukin-l receptor antagonist in rheumatoid arthritis.

Camp NJ, Cox A, di Giovine FS, McCabe D, Rich W, Duff GW.

Genes Immun. 2005 Sep;6(6):467-71.PMID: 15931231 [PubMed - indexed for MEDLINE]Related articles

Human interleukin-1 alpha gene expression is regulated by Sp1 and a transcriptional repressor.

McDowell TL, Symons JA, Duff GW.

Cytokine. 2005 May 21;30(4):141-53. Epub 2005 Feb 19.PMID: 15863387 [PubMed - indexed for MEDLINE]Related articles

Single-point haplotype scores telomeric to human leukocyte antigen-C give a high susceptibility major histocompatability complex haplotype for psoriasis in a caucasian population.

Lench N, Iles MM, Mackay I, Patel R, Sagoo GS, Ward SJ, Dechairo B, Olavesen M, Carey A, Duff GW, Cork MJ, Tazi-Ahnini R.

J Invest Dermatol. 2005 Mar;124(3):545-52.PMID: 15737195 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-1 polymorphisms are associated with the inflammatory response in human muscle to acute resistance exercise.

Dennis RA, Trappe TA, Simpson P, Carroll C, Huang BE, Nagarajan R, Bearden E, Gurley C, Duff GW, Evans WJ, Kornman K, Peterson CA.

J Physiol. 2004 Nov 1;560(Pt 3):617-26. Epub 2004 Aug 26.PMID: 15331687 [PubMed - indexed for MEDLINE]Related articlesFree article

The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis.

Timms AE, Crane AM, Sims AM, Cordell HJ, Bradbury LA, Abbott A, Coyne MR, Beynon O, Herzberg I, Duff GW, Calin A, Cardon LR, Wordsworth BP, Brown MA.

Am J Hum Genet. 2004 Oct;75(4):587-95. Epub 2004 Aug 12.PMID: 15309690 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic association between an AACC insertion in the 3'UTR of the stratum corneum chymotryptic enzyme gene and atopic dermatitis.

Vasilopoulos Y, Cork MJ, Murphy R, Williams HC, Robinson DA, Duff GW, Ward SJ, Tazi-Ahnini R.

J Invest Dermatol. 2004 Jul;123(1):62-6.PMID: 15191543 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional correlates of the interleukin-1 receptor antagonist gene polymorphism in the colonic mucosa in ulcerative colitis.

Carter MJ, Jones S, Camp NJ, Cox A, Mee J, Warren B, Duff GW, Lobo AJ, di Giovine FS.

Genes Immun. 2004 Jan;5(1):8-15.PMID: 14735144 [PubMed - indexed for MEDLINE]Related articles

Genetic variations and inflammation: a practical nutrigenomics opportunity.

Kornman KS, Martha PM, Duff GW.

Nutrition. 2004 Jan;20(1):44-9. Review. No abstract available. PMID: 14698013 [PubMed - indexed for MEDLINE]Related articles

Variation in the TNF gene promoter and risk of osteolysis after total hip arthroplasty.

Wilkinson JM, Wilson AG, Stockley I, Scott IR, Macdonald DA, Hamer AJ, Duff GW, Eastell R.

J Bone Miner Res. 2003 Nov;18(11):1995-2001.PMID: 14606512 [PubMed - indexed for MEDLINE]Related articles

Variation within genes encoding interleukin-1 and the interleukin-1 receptor antagonist influence the severity of meningococcal disease.

Read RC, Cannings C, Naylor SC, Timms JM, Maheswaran R, Borrow R, Kaczmarski EB, Duff GW.

Ann Intern Med. 2003 Apr 1;138(7):534-41.PMID: 12667023 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-1 gene polymorphism and smoking as risk factors for peri-implant bone loss in a well-maintained population.

Feloutzis A, Lang NP, Tonetti MS, Bürgin W, Brägger U, Buser D, Duff GW, Kornman KS.

Clin Oral Implants Res. 2003 Feb;14(1):10-7.PMID: 12562360 [PubMed - indexed for MEDLINE]Related articles

A sequence-based map of the nine genes of the human interleukin-1 cluster.

Nicklin MJ, Barton JL, Nguyen M, FitzGerald MG, Duff GW, Kornman K.

Genomics. 2002 May;79(5):718-25.PMID: 11991722 [PubMed - indexed for MEDLINE]Related articles

C-reactive protein levels are influenced by common IL-1 gene variations.

Berger P, McConnell JP, Nunn M, Kornman KS, Sorrell J, Stephenson K, Duff GW.

Cytokine. 2002 Feb 21;17(4):171-4.PMID: 11991668 [PubMed - indexed for MEDLINE]Related articles

Candidate genes as potential links between periodontal and cardiovascular diseases.

Kornman KS, Duff GW.

Ann Periodontol. 2001 Dec;6(1):48-57. Review.PMID: 11887471 [PubMed - indexed for MEDLINE]Related articles

Genetic analysis of the interleukin-1 receptor antagonist and its homologue IL-1L1 in alopecia areata: strong severity association and possible gene interaction.

Tazi-Ahnini R, Cox A, McDonagh AJ, Nicklin MJ, di Giovine FS, Timms JM, Messenger AG, Dimitropoulou P, Duff GW, Cork MJ.

Eur J Immunogenet. 2002 Feb;29(1):25-30.PMID: 11841485 [PubMed - indexed for MEDLINE]Related articles

Association analysis of IL1A and IL1B variants in alopecia areata.

Tazi-Ahnini R, McDonagh AJ, Cox A, Messenger AG, Britton JE, Ward SJ, Båvik CO, Duff GW, Cork MJ.

Heredity. 2001 Aug;87(Pt 2):215-9.PMID: 11703512 [PubMed - indexed for MEDLINE]Related articles

Analysis of the association between diabetic nephropathy and polymorphisms in the aldose reductase gene in Type 1 and Type 2 diabetes mellitus.

Neamat-Allah M, Feeney SA, Savage DA, Maxwell AP, Hanson RL, Knowler WC, El Nahas AM, Plater ME, Shaw J, Boulton AJ, Duff GW, Cox A.

Diabet Med. 2001 Nov;18(11):906-14.PMID: 11703436 [PubMed - indexed for MEDLINE]Related articles

The interleukin 1 receptor antagonist gene allele 2 as a predictor of pouchitis following colectomy and IPAA in ulcerative colitis.

Carter MJ, Di Giovine FS, Cox A, Goodfellow P, Jones S, Shorthouse AJ, Duff GW, Lobo AJ.

Gastroenterology. 2001 Oct;121(4):805-11.PMID: 11606494 [PubMed - indexed for MEDLINE]Related articles

A candidate gene analysis of three related photosensitivity disorders: cutaneous lupus erythematosus, polymorphic light eruption and actinic prurigo.

Millard TP, Kondeatis E, Cox A, Wilson AG, Grabczynska SA, Carey BS, Lewis CM, Khamashta MA, Duff GW, Hughes GR, Hawk JL, Vaughan RW, McGregor JM.

Br J Dermatol. 2001 Aug;145(2):229-36.PMID: 11531784 [PubMed - indexed for MEDLINE]Related articles

IL-1B and IL-1Ra gene polymorphisms and disease severity in rheumatoid arthritis: interaction with their plasma levels.

Buchs N, di Giovine FS, Silvestri T, Vannier E, Duff GW, Miossec P.

Genes Immun. 2001 Jun;2(4):222-8.PMID: 11477478 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the interleukin 1 receptor antagonist gene with ulcerative colitis in Northern European Caucasians.

Carter MJ, di Giovine FS, Jones S, Mee J, Camp NJ, Lobo AJ, Duff GW.

Gut. 2001 Apr;48(4):461-7.PMID: 11247888 [PubMed - indexed for MEDLINE]Related articlesFree article

Protective role against restenosis from an interleukin-1 receptor antagonist gene polymorphism in patients treated with coronary stenting.

Kastrati A, Koch W, Berger PB, Mehilli J, Stephenson K, Neumann FJ, von Beckerath N, Böttiger C, Duff GW, Schömig A.

J Am Coll Cardiol. 2000 Dec;36(7):2168-73.PMID: 11127457 [PubMed - indexed for MEDLINE]Related articles

Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses.

Wyllie DH, Kiss-Toth E, Visintin A, Smith SC, Boussouf S, Segal DM, Duff GW, Dower SK.

J Immunol. 2000 Dec 15;165(12):7125-32.PMID: 11120843 [PubMed - indexed for MEDLINE]Related articlesFree article

Microbiological parameters associated with IL-1 gene polymorphisms in periodontitis patients.

Socransky SS, Haffajee AD, Smith C, Duff GW.

J Clin Periodontol. 2000 Nov;27(11):810-8.PMID: 11073323 [PubMed - indexed for MEDLINE]Related articles

IL-4 VNTR gene polymorphism in chronic polyarthritis. The rare allele is associated with protection against destruction.

Buchs N, Silvestri T, di Giovine FS, Chabaud M, Vannier E, Duff GW, Miossec P.

Rheumatology (Oxford). 2000 Oct;39(10):1126-31.PMID: 11035134 [PubMed - indexed for MEDLINE]Related articlesFree article

An interleukin-1 genotype is associated with fatal outcome of meningococcal disease.

Read RC, Camp NJ, di Giovine FS, Borrow R, Kaczmarski EB, Chaudhary AG, Fox AJ, Duff GW.

J Infect Dis. 2000 Nov;182(5):1557-60. Epub 2000 Oct 9.PMID: 11023482 [PubMed - indexed for MEDLINE]Related articles

Structure and polymorphism of the human gene for the interferon-induced p78 protein (MX1): evidence of association with alopecia areata in the Down syndrome region.

Tazi-Ahnini R, di Giovine FS, McDonagh AJ, Messenger AG, Amadou C, Cox A, Duff GW, Cork MJ.

Hum Genet. 2000 Jun;106(6):639-45.PMID: 10942113 [PubMed - indexed for MEDLINE]Related articles

Effect of interleukin-1 gene polymorphisms on gingival inflammation assessed by bleeding on probing in a periodontal maintenance population.

Lang NP, Tonetti MS, Suter J, Sorrell J, Duff GW, Kornman KS.

J Periodontal Res. 2000 Apr;35(2):102-7.PMID: 10863964 [PubMed - indexed for MEDLINE]Related articles

Low prevalence of a periodontitis-associated interleukin-1 composite genotype in individuals of Chinese heritage.

Armitage GC, Wu Y, Wang HY, Sorrell J, di Giovine FS, Duff GW.

J Periodontol. 2000 Feb;71(2):164-71.PMID: 10711606 [PubMed - indexed for MEDLINE]Related articles

Interleukin-1 genetic association with periodontitis in clinical practice.

McDevitt MJ, Wang HY, Knobelman C, Newman MG, di Giovine FS, Timms J, Duff GW, Kornman KS.

J Periodontol. 2000 Feb;71(2):156-63.PMID: 10711605 [PubMed - indexed for MEDLINE]Related articles

Interleukin-1 genotypes and the association between periodontitis and cardiovascular disease.

Kornman KS, Pankow J, Offenbacher S, Beck J, di Giovine F, Duff GW.

J Periodontal Res. 1999 Oct;34(7):353-7.PMID: 10685360 [PubMed - indexed for MEDLINE]Related articles

Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene.

Nicklin MJ, Hughes DE, Barton JL, Ure JM, Duff GW.

J Exp Med. 2000 Jan 17;191(2):303-12.PMID: 10637274 [PubMed - indexed for MEDLINE]Related articlesFree article

Relevance of tumour necrosis factor alpha gene polymorphism in rheumatic disease.

Wilson AG, Duff GW.

Rheumatology (Oxford). 1999 Jul;38(7):681-3. No abstract available. PMID: 10461487 [PubMed - indexed for MEDLINE]Related articlesFree article

Primary biliary cirrhosis shows association with genetic polymorphism of tumour necrosis factor alpha promoter region.

Gordon MA, Oppenheim E, Camp NJ, di Giovine FS, Duff GW, Gleeson D.

J Hepatol. 1999 Aug;31(2):242-7.PMID: 10453936 [PubMed - indexed for MEDLINE]Related articles

Combined sib-TDT and TDT provide evidence for linkage of the interleukin-1 gene cluster to erosive rheumatoid arthritis.

Cox A, Camp NJ, Cannings C, di Giovine FS, Dale M, Worthington J, John S, Ollier WE, Silman AJ, Duff GW.

Hum Mol Genet. 1999 Sep;8(9):1707-13.PMID: 10441334 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis.

Tazi Ahnini R, Camp NJ, Cork MJ, Mee JB, Keohane SG, Duff GW, di Giovine FS.

Hum Mol Genet. 1999 Jun;8(6):1135-40. Erratum in: Hum Mol Genet 2000 Mar 1;9(4):659. PMID: 10332047 [PubMed - indexed for MEDLINE]Related articlesFree article

Possible genetic association between interleukin-1alpha gene polymorphism and the severity of chronic polyarthritis.

Jouvenne P, Chaudhary A, Buchs N, Giovine FS, Duff GW, Miossec P.

Eur Cytokine Netw. 1999 Mar;10(1):33-6.PMID: 10210770 [PubMed - indexed for MEDLINE]Related articles

Interleukin-1 receptor antagonist gene polymorphism and coronary artery disease.

Francis SE, Camp NJ, Dewberry RM, Gunn J, Syrris P, Carter ND, Jeffery S, Kaski JC, Cumberland DC, Duff GW, Crossman DC.

Circulation. 1999 Feb 23;99(7):861-6.PMID: 10027806 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-1 in myocardium and coronary arteries of patients with dilated cardiomyopathy.

Francis SE, Holden H, Holt CM, Duff GW.

J Mol Cell Cardiol. 1998 Feb;30(2):215-23.PMID: 9514998 [PubMed - indexed for MEDLINE]Related articles