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    Results: 1 to 50 of 192

    1.

    Intensive glucose control and macrovascular outcomes in type 2 diabetes.

    Turnbull FM, Abraira C, Anderson RJ, Byington RP, Chalmers JP, Duckworth WC, Evans GW, Gerstein HC, Holman RR, Moritz TE, Neal BC, Ninomiya T, Patel AA, Paul SK, Travert F, Woodward M.

    Diabetologia. 2009 Nov;52(11):2288-98. Epub 2009 Aug 5.PMID: 19655124 [PubMed - in process]Related articles

    2.

    Hyperglycaemia and hyperinsulinaemia: is insulin-degrading enzyme the missing link?

    Fawcett J, Duckworth WC.

    Diabetologia. 2009 Aug;52(8):1457-60. Epub 2009 Jun 6. No abstract available. PMID: 19504084 [PubMed - indexed for MEDLINE]Related articles

    3.

    Pioglitazone reduces inflammatory responses of human adipocytes to factors secreted by monocytes/macrophages.

    Permana PA, Zhang W, Wabitsch M, Fischer-Posovszky P, Duckworth WC, Reaven PD.

    Am J Physiol Endocrinol Metab. 2009 May;296(5):E1076-84. Epub 2009 Feb 24.PMID: 19240250 [PubMed - indexed for MEDLINE]Related articles

    4.

    Blood glucose monitoring is associated with better glycemic control in type 2 diabetes: a database study.

    Murata GH, Duckworth WC, Shah JH, Wendel CS, Mohler MJ, Hoffman RM.

    J Gen Intern Med. 2009 Jan;24(1):48-52. Epub 2008 Oct 31.PMID: 18975035 [PubMed - indexed for MEDLINE]Related articles

    5.

    Glycaemic separation and risk factor control in the Veterans Affairs Diabetes Trial: an interim report.

    Abraira C, Duckworth WC, Moritz T; VADT Group.

    Diabetes Obes Metab. 2009 Feb;11(2):150-6. Epub 2008 Jul 29.PMID: 18671796 [PubMed - indexed for MEDLINE]Related articles

    6.

    Regulation of protein degradation by insulin-degrading enzyme: analysis by small interfering RNA-mediated gene silencing.

    Fawcett J, Permana PA, Levy JL, Duckworth WC.

    Arch Biochem Biophys. 2007 Dec 1;468(1):128-33. Epub 2007 Sep 29. Erratum in: Arch Biochem Biophys. 2008 May 1;473(1):96. PMID: 17964527 [PubMed - indexed for MEDLINE]Related articles

    7.

    Adoption of a new technology in a Veterans Affairs national formulary system with local implementation: the insulin glargine example.

    Barengolts EI, Burke BV, Duckworth WC, Kaminsky R, Miller DR, Swislocki AL.

    Manag Care Interface. 2007 Mar;20(3):37-44, 57.PMID: 17458480 [PubMed - indexed for MEDLINE]Related articles

    8.

    Effect of nelfinavir on insulin metabolism, proteasome activity and protein degradation in HepG2 cells.

    Hamel FG, Fawcett J, Tsui BT, Bennett RG, Duckworth WC.

    Diabetes Obes Metab. 2006 Nov;8(6):661-8.PMID: 17026490 [PubMed - indexed for MEDLINE]Related articles

    9.

    Baseline achievement of lipid goals and usage of lipid medications in patients with diabetes mellitus (from the Veterans Affairs Diabetes Trial).

    Meyers CD, McCarren M, Wong ND, Abraira C, Duckworth WC, Kashyap ML; VADT Investigators.

    Am J Cardiol. 2006 Jul 1;98(1):63-5. Epub 2006 May 4.PMID: 16784922 [PubMed - indexed for MEDLINE]Related articles

    10.

    Racial and ethnic disparities in the control of cardiovascular disease risk factors in Southwest American veterans with type 2 diabetes: the Diabetes Outcomes in Veterans Study.

    Wendel CS, Shah JH, Duckworth WC, Hoffman RM, Mohler MJ, Murata GH.

    BMC Health Serv Res. 2006 May 23;6:58.PMID: 16716235 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Insulin glulisine: viewpoints.

    Dailey G, Ahmadian M, Duckworth WC, Eckel J.

    Drugs. 2006;66(6):870-2. No abstract available. PMID: 16706559 [PubMed - indexed for MEDLINE]Related articles

    12.

    Control of cardiovascular risk factors in the Veterans Affairs Diabetes Trial in advanced type 2 diabetes.

    Duckworth WC, McCarren M, Abraira C; VADT Investigators.

    Endocr Pract. 2006 Jan-Feb;12 Suppl 1:85-8. Review.PMID: 16627388 [PubMed - indexed for MEDLINE]Related articles

    13.

    Reliability and validity of the DCP among hispanic veterans.

    Cunningham V, Mohler MJ, Wendel CS, Hoffman RM, Murata GH, Shah JH, Duckworth WC.

    Eval Health Prof. 2005 Dec;28(4):447-63.PMID: 16272425 [PubMed - indexed for MEDLINE]Related articles

    14.

    Hypoglycemia in stable, insulin-treated veterans with type 2 diabetes: a prospective study of 1662 episodes.

    Murata GH, Duckworth WC, Shah JH, Wendel CS, Mohler MJ, Hoffman RM.

    J Diabetes Complications. 2005 Jan-Feb;19(1):10-7.PMID: 15642485 [PubMed - indexed for MEDLINE]Related articles

    15.

    Hypoglycemia in type 2 diabetes: a critical review.

    Murata GH, Duckworth WC, Hoffman RM, Wendel CS, Mohler MJ, Shah JH.

    Biomed Pharmacother. 2004 Dec;58(10):551-9. Review.PMID: 15589062 [PubMed - indexed for MEDLINE]Related articles

    16.

    Food frequency questionnaire results correlate with metabolic control in insulin-treated veterans with type 2 diabetes: the Diabetes Outcomes in Veterans Study.

    Murata GH, Shah JH, Duckworth WC, Wendel CS, Mohler MJ, Hoffman RM.

    J Am Diet Assoc. 2004 Dec;104(12):1816-26.PMID: 15565075 [PubMed - indexed for MEDLINE]Related articles

    17.

    Reduced action of insulin glargine on protein and lipid metabolism: possible relationship to cellular hormone metabolism.

    Fawcett J, Tsui BT, Kruer MC, Duckworth WC.

    Metabolism. 2004 Aug;53(8):1037-44.PMID: 15281015 [PubMed - indexed for MEDLINE]Related articles

    18.

    Determination of insulin requirements: excessive insulin dosages common in type 1 diabetes mellitus.

    Akhter J, Struebing P, Larsen JL, Gallagher TF, Ecklund R, Henley S, Mack-Shipman L, Duckworth WC.

    Endocr Pract. 1998 May-Jun;4(3):133-6.PMID: 15251740 [PubMed]Related articles

    19.

    A probabilistic model for predicting hypoglycemia in type 2 diabetes mellitus: The Diabetes Outcomes in Veterans Study (DOVES).

    Murata GH, Hoffman RM, Shah JH, Wendel CS, Duckworth WC.

    Arch Intern Med. 2004 Jul 12;164(13):1445-50.PMID: 15249354 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Contributions of weekly mean blood glucose values to hemoglobin A1c in insulin-treated type 2 diabetes: the Diabetes Outcomes in Veterans Study (DOVES).

    Murata GH, Hoffman RM, Duckworth WC, Wendel CS, Shah JH; Diabetes Outcomes in Veterans Study.

    Am J Med Sci. 2004 Jun;327(6):319-23.PMID: 15201644 [PubMed - indexed for MEDLINE]Related articles

    21.

    Factors affecting hypoglycemia awareness in insulin-treated type 2 diabetes: The Diabetes Outcomes in Veterans Study (DOVES).

    Murata GH, Duckworth WC, Shah JH, Wendel CS, Hoffman RM; Diabetes Outcomes in Veterans Study.

    Diabetes Res Clin Pract. 2004 Jul;65(1):61-7.PMID: 15163479 [PubMed - indexed for MEDLINE]Related articles

    22.

    Biological activity of a fragment of insulin.

    Duckworth WC, Fawcett J, Tsui BT, Bennett RG, Hamel FG.

    Biochem Biophys Res Commun. 2004 Jun 11;318(4):1019-24.PMID: 15147975 [PubMed - indexed for MEDLINE]Related articles

    23.

    Control of proteolysis: hormones, nutrients, and the changing role of the proteasome.

    Hamel FG, Fawcett J, Bennett RG, Duckworth WC.

    Curr Opin Clin Nutr Metab Care. 2004 May;7(3):255-8. Review.PMID: 15075915 [PubMed - indexed for MEDLINE]Related articles

    24.

    Sources of glucose variability in insulin-treated type 2 diabetes: the Diabetes Outcomes in Veterans Study (DOVES).

    Murata GH, Duckworth WC, Shah JH, Wendel CS, Hoffman RM.

    Clin Endocrinol (Oxf). 2004 Apr;60(4):451-6.PMID: 15049959 [PubMed - indexed for MEDLINE]Related articles

    25.

    Insulin inhibition of protein degradation in cells expressing wild-type and mutant insulin receptors.

    Hamel FG, Fawcett J, Andersen CI, Berhanu P, Bennett RG, Duckworth WC.

    J Endocrinol Invest. 2003 Nov;26(11):1088-94.PMID: 15008246 [PubMed - indexed for MEDLINE]Related articles

    26.

    Insulin-degrading activity in wound fluid.

    Duckworth WC, Fawcett J, Reddy S, Page JC.

    J Clin Endocrinol Metab. 2004 Feb;89(2):847-51.PMID: 14764804 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    Inhibition of proteasome activity by selected amino acids.

    Hamel FG, Upward JL, Siford GL, Duckworth WC.

    Metabolism. 2003 Jul;52(7):810-4.PMID: 12870152 [PubMed - indexed for MEDLINE]Related articles

    29.

    Factors affecting diabetes knowledge in Type 2 diabetic veterans.

    Murata GH, Shah JH, Adam KD, Wendel CS, Bokhari SU, Solvas PA, Hoffman RM, Duckworth WC.

    Diabetologia. 2003 Aug;46(8):1170-8. Epub 2003 Jul 11.PMID: 12856126 [PubMed - indexed for MEDLINE]Related articles

    30.

    Risk factor management in stable, insulin-treated patients with Type 2 diabetes: the Diabetes Outcomes in Veterans Study.

    Murata GH, Shah JH, Wendel CS, Hoffman RM, Adam KD, Bokhari SU, Solvas PA, Duckworth WC.

    J Diabetes Complications. 2003 Jul-Aug;17(4):186-91.PMID: 12810241 [PubMed - indexed for MEDLINE]Related articles

    31.

    Insulin inhibition of the proteasome is dependent on degradation of insulin by insulin-degrading enzyme.

    Bennett RG, Fawcett J, Kruer MC, Duckworth WC, Hamel FG.

    J Endocrinol. 2003 Jun;177(3):399-405.PMID: 12773120 [PubMed - indexed for MEDLINE]Related articlesFree article

    32.

    Intensified blood glucose monitoring improves glycemic control in stable, insulin-treated veterans with type 2 diabetes: the Diabetes Outcomes in Veterans Study (DOVES).

    Murata GH, Shah JH, Hoffman RM, Wendel CS, Adam KD, Solvas PA, Bokhari SU, Duckworth WC; Diabetes Outcomes in Veterans Study (DOVES).

    Diabetes Care. 2003 Jun;26(6):1759-63.PMID: 12766106 [PubMed - indexed for MEDLINE]Related articlesFree article

    33.

    Beneficial effects of a glyburide/metformin combination preparation in type 2 diabetes mellitus.

    Bokhari SU, Gopal UM, Duckworth WC.

    Am J Med Sci. 2003 Feb;325(2):66-9.PMID: 12589230 [PubMed - indexed for MEDLINE]Related articles

    34.

    Evaluating once- and twice-daily self-monitored blood glucose testing strategies for stable insulin-treated patients with type 2 diabetes : the diabetes outcomes in veterans study.

    Hoffman RM, Shah JH, Wendel CS, Duckworth WC, Adam KD, Bokhari SU, Dalton C, Murata GH; Diabetes Outcome in Veterans Study.

    Diabetes Care. 2002 Oct;25(10):1744-8.PMID: 12351471 [PubMed - indexed for MEDLINE]Related articlesFree article

    35.

    Advances in the treatment of diabetes-insulin analogues.

    Vajo Z, Duckworth WC.

    Minerva Endocrinol. 2002 Sep;27(3):167-80. Review.PMID: 12091792 [PubMed - indexed for MEDLINE]Related articles

    36.

    Recombinant DNA technology in the treatment of diabetes: insulin analogs.

    Vajo Z, Fawcett J, Duckworth WC.

    Endocr Rev. 2001 Oct;22(5):706-17. Review.PMID: 11588149 [PubMed - indexed for MEDLINE]Related articlesFree article

    37.

    Hyperglycemia and cardiovascular disease.

    Duckworth WC.

    Curr Atheroscler Rep. 2001 Sep;3(5):383-91. Review.PMID: 11487449 [PubMed - indexed for MEDLINE]Related articles

    38.

    Characterization of the inhibition of protein degradation by insulin in L6 cells.

    Fawcett J, Hamel FG, Duckworth WC.

    Arch Biochem Biophys. 2001 Jan 15;385(2):357-63.PMID: 11368017 [PubMed - indexed for MEDLINE]Related articles

    39.

    Insulin inhibits peroxisomal fatty acid oxidation in isolated rat hepatocytes.

    Hamel FG, Bennett RG, Upward JL, Duckworth WC.

    Endocrinology. 2001 Jun;142(6):2702-6.PMID: 11356722 [PubMed - indexed for MEDLINE]Related articlesFree article

    40.

    Glucose control and cardiovascular complications: the VA Diabetes Trial.

    Duckworth WC, McCarren M, Abraira C; VA Diabetes Trial.

    Diabetes Care. 2001 May;24(5):942-5. No abstract available. PMID: 11347758 [PubMed - indexed for MEDLINE]Related articlesFree article

    41.

    Insulin pumps and glucose regulation.

    Thompson JS, Duckworth WC.

    World J Surg. 2001 Apr;25(4):523-6. Epub 2001 Apr 11. Review.PMID: 11344407 [PubMed - indexed for MEDLINE]Related articles

    42.

    Insulin and analogue effects on protein degradation in different cell types. Dissociation between binding and activity.

    Fawcett J, Hamel FG, Bennett RG, Vajo Z, Duckworth WC.

    J Biol Chem. 2001 Apr 13;276(15):11552-8. Epub 2000 Dec 14.PMID: 11116143 [PubMed - indexed for MEDLINE]Related articlesFree article

    43.

    Degradation of amylin by insulin-degrading enzyme.

    Bennett RG, Duckworth WC, Hamel FG.

    J Biol Chem. 2000 Nov 24;275(47):36621-5.PMID: 10973971 [PubMed - indexed for MEDLINE]Related articlesFree article

    44.

    Insulin inhibits the ubiquitin-dependent degrading activity of the 26S proteasome.

    Bennett RG, Hamel FG, Duckworth WC.

    Endocrinology. 2000 Jul;141(7):2508-17.PMID: 10875252 [PubMed - indexed for MEDLINE]Related articlesFree article

    45.

    Genetically engineered insulin analogs: diabetes in the new millenium.

    Vajo Z, Duckworth WC.

    Pharmacol Rev. 2000 Mar;52(1):1-9. Review.PMID: 10699152 [PubMed - indexed for MEDLINE]Related articlesFree article

    46.

    Hepatitis A-induced diabetes mellitus, acute renal failure, and liver failure.

    Vesely DL, Dilley RW, Duckworth WC, Paustian FF.

    Am J Med Sci. 1999 Jun;317(6):419-24. Review.PMID: 10372844 [PubMed - indexed for MEDLINE]Related articles

    47.

    Differences in the cellular processing of AspB10 human insulin compared with human insulin and LysB28ProB29 human insulin.

    Hamel FG, Siford GL, Fawcett J, Chance RE, Frank BH, Duckworth WC.

    Metabolism. 1999 May;48(5):611-7.PMID: 10337862 [PubMed - indexed for MEDLINE]Related articles

    48.

    Surgical experience with implantable insulin pumps. Department of Veterans Affairs Implantable Insulin Pump Study Group.

    Thompson JS, Duckworth WC, Saudek CD, Giobbie-Hurder A.

    Am J Surg. 1998 Dec;176(6):622-6.PMID: 9926802 [PubMed - indexed for MEDLINE]Related articles

    49.

    Insulin degradation: progress and potential.

    Duckworth WC, Bennett RG, Hamel FG.

    Endocr Rev. 1998 Oct;19(5):608-24. Review.PMID: 9793760 [PubMed - indexed for MEDLINE]Related articlesFree article

    50.

    The Veterans Affairs Implantable Insulin Pump Study: effect on cardiovascular risk factors.

    Duckworth WC, Saudek CD, Giobbie-Hurder A, Henderson WG, Henry RR, Kelley DE, Edelman SV, Zieve FJ, Adler RA, Anderson JW, Anderson RJ, Hamilton BP, Donner TW, Kirkman MS, Morgan NA.

    Diabetes Care. 1998 Oct;21(10):1596-602.PMID: 9773717 [PubMed - indexed for MEDLINE]Related articlesFree article

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