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    Results: 22

    1.

    Poly(Adenosine 5'-Diphosphate-Ribose) Polymerase Inhibition Counteracts Multiple Manifestations of Experimental Type 1 Diabetic Nephropathy.

    Drel VR, Xu W, Zhang J, Pavlov IA, Shevalye H, Slusher B, Obrosova IG.

    Endocrinology. 2009 Oct 23. [Epub ahead of print]PMID: 19854869 [PubMed - as supplied by publisher]Related articles

    2.

    Peripheral neuropathy in mice with neuronal nitric oxide synthase gene deficiency.

    Vareniuk I, Pacher P, Pavlov IA, Drel VR, Obrosova IG.

    Int J Mol Med. 2009 May;23(5):571-80.PMID: 19360314 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Poly(ADP-ribose)polymerase inhibition counteracts cataract formation and early retinal changes in streptozotocin-diabetic rats.

    Drel VR, Xu W, Zhang J, Kador PF, Ali TK, Shin J, Julius U, Slusher B, El-Remessy AB, Obrosova IG.

    Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1778-90. Epub 2008 Dec 20.PMID: 19098320 [PubMed - indexed for MEDLINE]Related articles

    4.

    Nitrosylated proteins in monocytes as a new marker of oxidative-nitrosative stress in diabetic subjects with macroangiopathy.

    Julius U, Drel VR, Grässler J, Obrosova IG.

    Exp Clin Endocrinol Diabetes. 2009 Feb;117(2):72-7. Epub 2008 Aug 25.PMID: 18726872 [PubMed - indexed for MEDLINE]Related articles

    5.

    Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, retinal oxidative-nitrosative stress, glial activation, and apoptosis.

    Drel VR, Pacher P, Ali TK, Shin J, Julius U, El-Remessy AB, Obrosova IG.

    Int J Mol Med. 2008 Jun;21(6):667-76.PMID: 18506358 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Evaluation of the peroxynitrite decomposition catalyst Fe(III) tetra-mesitylporphyrin octasulfonate on peripheral neuropathy in a mouse model of type 1 diabetes.

    Drel VR, Pacher P, Vareniuk I, Pavlov IA, Ilnytska O, Lyzogubov VV, Bell SR, Groves JT, Obrosova IG.

    Int J Mol Med. 2007 Dec;20(6):783-92.PMID: 17982684 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy.

    Obrosova IG, Xu W, Lyzogubov VV, Ilnytska O, Mashtalir N, Vareniuk I, Pavlov IA, Zhang J, Slusher B, Drel VR.

    Free Radic Biol Med. 2008 Mar 15;44(6):972-81. Epub 2007 Oct 3.PMID: 17976390 [PubMed - indexed for MEDLINE]Related articles

    8.

    Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin-diabetic rats.

    Obrosova IG, Drel VR, Oltman CL, Mashtalir N, Tibrewala J, Groves JT, Yorek MA.

    Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1645-55. Epub 2007 Oct 2.PMID: 17911342 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice.

    Drel VR, Pacher P, Vareniuk I, Pavlov I, Ilnytska O, Lyzogubov VV, Tibrewala J, Groves JT, Obrosova IG.

    Eur J Pharmacol. 2007 Aug 13;569(1-2):48-58. Epub 2007 Jun 9.PMID: 17644085 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    High-fat diet induced neuropathy of pre-diabetes and obesity: effects of "healthy" diet and aldose reductase inhibition.

    Obrosova IG, Ilnytska O, Lyzogubov VV, Pavlov IA, Mashtalir N, Nadler JL, Drel VR.

    Diabetes. 2007 Oct;56(10):2598-608. Epub 2007 Jul 12.PMID: 17626889 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice.

    Vareniuk I, Pavlov IA, Drel VR, Lyzogubov VV, Ilnytska O, Bell SR, Tibrewala J, Groves JT, Obrosova IG.

    Exp Neurol. 2007 Jun;205(2):425-36. Epub 2007 Mar 27.PMID: 17475250 [PubMed - indexed for MEDLINE]Related articles

    12.

    Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption.

    Rajesh M, Mukhopadhyay P, Bátkai S, Haskó G, Liaudet L, Drel VR, Obrosova IG, Pacher P.

    Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H610-9. Epub 2007 Mar 23.PMID: 17384130 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    The leptin-deficient (ob/ob) mouse: a new animal model of peripheral neuropathy of type 2 diabetes and obesity.

    Drel VR, Mashtalir N, Ilnytska O, Shin J, Li F, Lyzogubov VV, Obrosova IG.

    Diabetes. 2006 Dec;55(12):3335-43.PMID: 17130477 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Nicotinamide reverses neurological and neurovascular deficits in streptozotocin diabetic rats.

    Stevens MJ, Li F, Drel VR, Abatan OI, Kim H, Burnett D, Larkin D, Obrosova IG.

    J Pharmacol Exp Ther. 2007 Jan;320(1):458-64. Epub 2006 Oct 4.PMID: 17021258 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Early diabetes-induced biochemical changes in the retina: comparison of rat and mouse models.

    Obrosova IG, Drel VR, Kumagai AK, Szábo C, Pacher P, Stevens MJ.

    Diabetologia. 2006 Oct;49(10):2525-33. Epub 2006 Aug 1.PMID: 16896942 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy.

    Ilnytska O, Lyzogubov VV, Stevens MJ, Drel VR, Mashtalir N, Pacher P, Yorek MA, Obrosova IG.

    Diabetes. 2006 Jun;55(6):1686-94.PMID: 16731831 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells.

    Drel VR, Pacher P, Stevens MJ, Obrosova IG.

    Free Radic Biol Med. 2006 Apr 15;40(8):1454-65. Epub 2006 Jan 31.PMID: 16631535 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Oxidative-nitrosative stress and poly(ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited.

    Obrosova IG, Drel VR, Pacher P, Ilnytska O, Wang ZQ, Stevens MJ, Yorek MA.

    Diabetes. 2005 Dec;54(12):3435-41.PMID: 16306359 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Low-dose poly(ADP-ribose) polymerase inhibitor-containing combination therapies reverse early peripheral diabetic neuropathy.

    Li F, Drel VR, Szabó C, Stevens MJ, Obrosova IG.

    Diabetes. 2005 May;54(5):1514-22.PMID: 15855340 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Multiple domains of Ruk/CIN85/SETA/CD2BP3 are involved in interaction with p85alpha regulatory subunit of PI 3-kinase.

    Borthwick EB, Korobko IV, Luke C, Drel VR, Fedyshyn YY, Ninkina N, Drobot LB, Buchman VL.

    J Mol Biol. 2004 Oct 29;343(4):1135-46.PMID: 15476827 [PubMed - indexed for MEDLINE]Related articles

    21.

    Adaptor protein Ruk1 forms protein-protein complexes with endonuclease activity in HEK293 cells.

    Kit YY, Drel VR, Petriv OI, Kovalyova VA, Shuvaeva GY, Palivoda OY, Vovk EI, Bobak YP, Rzeszowska-Wolny J, Gout IT, Buchman VL, Drobot LB.

    Biochemistry (Mosc). 2003 Jul;68(7):810-5.PMID: 12946264 [PubMed - indexed for MEDLINE]Related articles

    22.

    [Study of expression of desoxyribonucleases in mammalian cells by a protein renaturation method in polyacrylamide gel]

    Kit IuIa, Shuvaieva HIu, Drel' VR, Ihumentseva NI, Drobot LB.

    Ukr Biokhim Zh. 2002 May-Jun;74(3):116-9. Ukrainian. PMID: 12916248 [PubMed - indexed for MEDLINE]Related articles

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