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Cytotoxic T lymphocyte antigen-4 Ala17 polymorphism is a genetic marker of autoimmune adrenal insufficiency: Italian association study and meta-analysis of European studies.

Brozzetti A, Marzotti S, Tortoioli C, Bini V, Giordano R, Dotta F, Betterle C, De Bellis A, Arnaldi G, Toscano V, Arvat E, Bellastella A, Mantero F, Falorni A.

Eur J Endocrinol. 2009 Nov 2. [Epub ahead of print]PMID: 19884265 [PubMed - as supplied by publisher]Related articles

Diagnosis and approach to posttransplant diabetes.

Bonato V, Cataldo D, Dotta F, Carmellini M.

Curr Diab Rep. 2009 Aug;9(4):317-23. Review.PMID: 19640346 [PubMed - indexed for MEDLINE]Related articles

Comparison of vildagliptin and pioglitazone in patients with type 2 diabetes inadequately controlled with metformin.

Bolli G, Dotta F, Colin L, Minic B, Goodman M.

Diabetes Obes Metab. 2009 Jun;11(6):589-95. Epub 2009 Apr 13.PMID: 19515179 [PubMed - in process]Related articles

Vildagliptin plus metformin combination therapy provides superior glycaemic control to individual monotherapy in treatment-naive patients with type 2 diabetes mellitus.

Bosi E, Dotta F, Jia Y, Goodman M.

Diabetes Obes Metab. 2009 May;11(5):506-15. Epub 2009 Mar 23.PMID: 19320662 [PubMed - in process]Related articles

GAD and IA-2 autoantibody detection in type 1 diabetic patient saliva.

Tiberti C, Shashaj B, Verrienti A, Vecci EG, Lucantoni F, Masotti D, Morano S, Sulli N, Dotta F.

Clin Immunol. 2009 May;131(2):271-6. Epub 2009 Jan 21.PMID: 19162555 [PubMed - indexed for MEDLINE]Related articles

Hedgehog signaling during expansion of human pancreatic islet-derived precursors.

Gallo R, Grieco FA, Marselli L, Ferretti E, Gulino A, Marchetti P, Dotta F.

Ann N Y Acad Sci. 2008 Dec;1150:43-5.PMID: 19120265 [PubMed - indexed for MEDLINE]Related articles

Can NK cells be a therapeutic target in human type 1 diabetes?

Dotta F, Fondelli C, Falorni A.

Eur J Immunol. 2008 Nov;38(11):2961-3. Review.PMID: 18979518 [PubMed - indexed for MEDLINE]Related articles

Analysis of posttransplant diabetes mellitus prevalence in a population of kidney transplant recipients.

Bonato V, Barni R, Cataldo D, Collini A, Ruggieri G, De Bartolomeis C, Dotta F, Carmellini M.

Transplant Proc. 2008 Jul-Aug;40(6):1888-90.PMID: 18675080 [PubMed - indexed for MEDLINE]Related articles

Identification of tyrosine phosphatase 2(256-760) construct as a new, sensitive marker for the detection of islet autoimmunity in type 2 diabetic patients: the non-insulin requiring autoimmune diabetes (NIRAD) study 2.

Tiberti C, Giordano C, Locatelli M, Bosi E, Bottazzo GF, Buzzetti R, Cucinotta D, Galluzzo A, Falorni A, Dotta F.

Diabetes. 2008 May;57(5):1276-83. Epub 2008 Mar 10.PMID: 18332100 [PubMed - indexed for MEDLINE]Related articlesFree article

Thyrotoxic periodic paralysis in an Italian man: clinical manifestation and genetic analysis.

Vendrame F, Verrienti A, Parlapiano C, Filetti S, Dotta F, Morano S.

Ann Clin Biochem. 2008 Mar;45(Pt 2):218-20.PMID: 18325191 [PubMed - indexed for MEDLINE]Related articles

Generalised reduction of putative endothelial progenitors and CXCR4-positive peripheral blood cells in type 2 diabetes.

Egan CG, Lavery R, Caporali F, Fondelli C, Laghi-Pasini F, Dotta F, Sorrentino V.

Diabetologia. 2008 Jul;51(7):1296-305. Epub 2008 Feb 20.PMID: 18286257 [PubMed - indexed for MEDLINE]Related articles

Efficacy and tolerability of vildagliptin vs. pioglitazone when added to metformin: a 24-week, randomized, double-blind study.

Bolli G, Dotta F, Rochotte E, Cohen SE.

Diabetes Obes Metab. 2008 Jan;10(1):82-90. Epub 2007 Nov 22.PMID: 18034842 [PubMed - indexed for MEDLINE]Related articles

An overview of pancreatic beta-cell defects in human type 2 diabetes: implications for treatment.

Marchetti P, Dotta F, Lauro D, Purrello F.

Regul Pept. 2008 Feb 7;146(1-3):4-11. Epub 2007 Aug 29. Review.PMID: 17889380 [PubMed - indexed for MEDLINE]Related articles

Type VII collagen in Alport syndrome.

Giannakakis K, Massella L, Grassetti D, Dotta F, Perez M, Muda AO.

Nephrol Dial Transplant. 2007 Dec;22(12):3501-7. Epub 2007 Aug 1.PMID: 17670768 [PubMed - indexed for MEDLINE]Related articlesFree article

Generation and expansion of multipotent mesenchymal progenitor cells from cultured human pancreatic islets.

Gallo R, Gambelli F, Gava B, Sasdelli F, Tellone V, Masini M, Marchetti P, Dotta F, Sorrentino V.

Cell Death Differ. 2007 Nov;14(11):1860-71. Epub 2007 Jul 6.PMID: 17612586 [PubMed - indexed for MEDLINE]Related articlesFree article

High titer of autoantibodies to GAD identifies a specific phenotype of adult-onset autoimmune diabetes.

Buzzetti R, Di Pietro S, Giaccari A, Petrone A, Locatelli M, Suraci C, Capizzi M, Arpi ML, Bazzigaluppi E, Dotta F, Bosi E; Non Insulin Requiring Autoimmune Diabetes Study Group.

Diabetes Care. 2007 Apr;30(4):932-8.PMID: 17392553 [PubMed - indexed for MEDLINE]Related articlesFree article

Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients.

Dotta F, Censini S, van Halteren AG, Marselli L, Masini M, Dionisi S, Mosca F, Boggi U, Muda AO, Prato SD, Elliott JF, Covacci A, Rappuoli R, Roep BO, Marchetti P.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5115-20. Epub 2007 Mar 14.PMID: 17360338 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired caspase-3 expression by peripheral T cells in chronic autoimmune thyroiditis and in autoimmune polyendocrine syndrome-2.

Vendrame F, Segni M, Grassetti D, Tellone V, Augello G, Trischitta V, Torlontano M, Dotta F.

J Clin Endocrinol Metab. 2006 Dec;91(12):5064-8. Epub 2006 Sep 12.PMID: 16968794 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 1 diabetes mellitus as a polygenic multifactorial disease: immunopathogenic mechanisms of beta-cell destruction.

Dotta F, Fondelli C, Di Mario U.

Acta Biomed. 2005;76 Suppl 3:14-8. No abstract available. PMID: 16915790 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence of a selective epitope loss of anti-transglutaminase immunoreactivity in gluten-free diet celiac sera: a new tool to distinguish disease-specific immunoreactivities.

Tiberti C, Bonamico M, Dotta F, Verrienti A, Di Tola M, Liu E, Ferri M, Nenna R, Picarelli A, Eisenbarth GS.

Clin Immunol. 2006 Oct;121(1):40-6. Epub 2006 Jun 23.PMID: 16798097 [PubMed - indexed for MEDLINE]Related articles

Latent autoimmune diabetes in adults (LADA) should be less latent.

Fourlanos S, Dotta F, Greenbaum CJ, Palmer JP, Rolandsson O, Colman PG, Harrison LC.

Diabetologia. 2005 Nov;48(11):2206-12. Epub 2005 Sep 29. Review.PMID: 16193284 [PubMed - indexed for MEDLINE]Related articles

Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse.

Calcinaro F, Dionisi S, Marinaro M, Candeloro P, Bonato V, Marzotti S, Corneli RB, Ferretti E, Gulino A, Grasso F, De Simone C, Di Mario U, Falorni A, Boirivant M, Dotta F.

Diabetologia. 2005 Aug;48(8):1565-75. Epub 2005 Jun 29.PMID: 15986236 [PubMed - indexed for MEDLINE]Related articles

IA-2 combined epitope assay: a new, highly sensitive approach to evaluate IA-2 humoral autoimmunity in type 1 diabetes.

Tiberti C, Verrienti A, Fiore B, Yu L, Eisenbarth GS, Dotta F, Di Mario U.

Clin Immunol. 2005 Jun;115(3):260-7.PMID: 15893693 [PubMed - indexed for MEDLINE]Related articles

Guidelines for the treatment and management of new-onset diabetes after transplantation.

Wilkinson A, Davidson J, Dotta F, Home PD, Keown P, Kiberd B, Jardine A, Levitt N, Marchetti P, Markell M, Naicker S, O'Connell P, Schnitzler M, Standl E, Torregosa JV, Uchida K, Valantine H, Villamil F, Vincenti F, Wissing M.

Clin Transplant. 2005 Jun;19(3):291-8. Review.PMID: 15877787 [PubMed - indexed for MEDLINE]Related articles

The acquisition of an insulin-secreting phenotype by HGF-treated rat pancreatic ductal cells (ARIP) is associated with the development of susceptibility to cytokine-induced apoptosis.

Anastasi E, Santangelo C, Bulotta A, Dotta F, Argenti B, Mincione C, Gulino A, Maroder M, Perfetti R, Di Mario U.

J Mol Endocrinol. 2005 Apr;34(2):367-76.PMID: 15821103 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective lymphocyte caspase-3 expression in type 1 diabetes mellitus.

Vendrame F, Santangelo C, Misasi R, Dionisi S, Gizzi C, Realacci M, Grassetti D, Di Mario U, Dotta F.

Eur J Endocrinol. 2005 Jan;152(1):119-25.PMID: 15762195 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppressor of cytokine signaling gene expression in human pancreatic islets: modulation by cytokines.

Santangelo C, Scipioni A, Marselli L, Marchetti P, Dotta F.

Eur J Endocrinol. 2005 Mar;152(3):485-9.PMID: 15757867 [PubMed - indexed for MEDLINE]Related articlesFree article

CD4+CD25high regulatory T cells in human autoimmune diabetes.

Putnam AL, Vendrame F, Dotta F, Gottlieb PA.

J Autoimmun. 2005 Feb;24(1):55-62. Epub 2005 Jan 12.PMID: 15725577 [PubMed - indexed for MEDLINE]Related articles

The role of peripheral benzodiazepine receptors on the function and survival of isolated human pancreatic islets.

Marselli L, Trincavelli L, Santangelo C, Lupi R, Del Guerra S, Boggi U, Falleni A, Gremigni V, Mosca F, Martini C, Dotta F, Di Mario U, Del Prato S, Marchetti P.

Eur J Endocrinol. 2004 Aug;151(2):207-14.PMID: 15296476 [PubMed - indexed for MEDLINE]Related articlesFree article

Markers of beta cell function in type 1 diabetes mellitus.

Vendrame F, Zappaterreno A, Dotta F.

Minerva Med. 2004 Apr;95(2):79-84. Review.PMID: 15272242 [PubMed - indexed for MEDLINE]Related articles

Role of caspases in the regulation of apoptotic pancreatic islet beta-cells death.

Hui H, Dotta F, Di Mario U, Perfetti R.

J Cell Physiol. 2004 Aug;200(2):177-200. Review.PMID: 15174089 [PubMed - indexed for MEDLINE]Related articles

Improved insulin secretory function and reduced chemotactic properties after tissue culture of islets from type 1 diabetic patients.

Lupi R, Marselli L, Dionisi S, Del Guerra S, Boggi U, Del Chiaro M, Lencioni C, Bugliani M, Mosca F, Di Mario U, Del Prato S, Dotta F, Marchetti P.

Diabetes Metab Res Rev. 2004 May-Jun;20(3):246-51.PMID: 15133757 [PubMed - indexed for MEDLINE]Related articles

Italian addison network study: update of diagnostic criteria for the etiological classification of primary adrenal insufficiency.

Falorni A, Laureti S, De Bellis A, Zanchetta R, Tiberti C, Arnaldi G, Bini V, Beck-Peccoz P, Bizzarro A, Dotta F, Mantero F, Bellastella A, Betterle C, Santeusanio F; SIE Addison Study Group.

J Clin Endocrinol Metab. 2004 Apr;89(4):1598-604.PMID: 15070918 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between the effect of spontaneous contrast in the thoracic aorta and recent ischemic stroke determined by transesophageal echocardiography.

Velho FJ, Dotta F, Scherer L, Bartholomay E, da Silva DA, Fernandes JG, Torres MA.

Arq Bras Cardiol. 2004 Jan;82(1):52-6, 47-51. Epub 2004 Feb 12. English, Portuguese. PMID: 14978594 [PubMed - indexed for MEDLINE]Related articlesFree article

Celiac disease-associated transglutaminase autoantibody target domains at diagnosis are age and sex dependent.

Tiberti C, Bao F, Bonamico M, Verrienti A, Picarelli A, Di Tola M, Ferri M, Vecci E, Dotta F, Eisenbarth GS, Di Mario U.

Clin Immunol. 2003 Dec;109(3):318-24.PMID: 14697746 [PubMed - indexed for MEDLINE]Related articles

New-onset diabetes after transplantation: 2003 International consensus guidelines. Proceedings of an international expert panel meeting. Barcelona, Spain, 19 February 2003.

Davidson J, Wilkinson A, Dantal J, Dotta F, Haller H, Hernández D, Kasiske BL, Kiberd B, Krentz A, Legendre C, Marchetti P, Markell M, van der Woude FJ, Wheeler DC; International Expert Panel.

Transplantation. 2003 May 27;75(10 Suppl):SS3-24. Review. No abstract available. PMID: 12775942 [PubMed - indexed for MEDLINE]Related articles

Neonatal syndromes of polyendocrinopathy.

Dotta F, Vendrame F.

Endocrinol Metab Clin North Am. 2002 Jun;31(2):283-93, v. Review.PMID: 12092451 [PubMed - indexed for MEDLINE]Related articles

Application of phage display peptide library to autoimmune diabetes: identification of IA-2/ICA512bdc dominant autoantigenic epitopes.

Farilla L, Tiberti C, Luzzago A, Yu L, Eisenbarth GS, Cortese R, Dotta F, Di Mario U.

Eur J Immunol. 2002 May;32(5):1420-7.PMID: 11981830 [PubMed - indexed for MEDLINE]Related articles

Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

Lupi R, Dotta F, Marselli L, Del Guerra S, Masini M, Santangelo C, Patané G, Boggi U, Piro S, Anello M, Bergamini E, Mosca F, Di Mario U, Del Prato S, Marchetti P.

Diabetes. 2002 May;51(5):1437-42.PMID: 11978640 [PubMed - indexed for MEDLINE]Related articlesFree article

ICA512(IA-2) epitope specific assays distinguish transient from diabetes associated autoantibodies.

Miao D, Yu L, Tiberti C, Cuthbertson DD, Rewers M, di Mario U, Eisenbarth GS, Dotta F.

J Autoimmun. 2002 Mar;18(2):191-6.PMID: 11908951 [PubMed - indexed for MEDLINE]Related articles

Upregulation of mitochondrial peripheral benzodiazepine receptor expression by cytokine-induced damage of human pancreatic islets.

Trincavelli ML, Marselli L, Falleni A, Gremigni V, Ragge E, Dotta F, Santangelo C, Marchetti P, Lucacchini A, Martini C.

J Cell Biochem. 2002;84(3):636-44.PMID: 11813268 [PubMed - indexed for MEDLINE]Related articles

Th2 cytokines have a partial, direct protective effect on the function and survival of isolated human islets exposed to combined proinflammatory and Th1 cytokines.

Marselli L, Dotta F, Piro S, Santangelo C, Masini M, Lupi R, Realacci M, del Guerra S, Mosca F, Boggi U, Purrello F, Navalesi R, Marchetti P.

J Clin Endocrinol Metab. 2001 Oct;86(10):4974-8.PMID: 11600573 [PubMed - indexed for MEDLINE]Related articlesFree article

Bovine islets are less susceptible than human islets to damage by human cytokines.

Piro S, Lupi R, Dotta F, Patanè G, Rabuazzo MA, Marselli L, Santangelo C, Realacci M, Del Guerra S, Purrello F, Marchetti P.

Transplantation. 2001 Jan 15;71(1):21-6.PMID: 11211190 [PubMed - indexed for MEDLINE]Related articles

Presence of interleukin 4 or interleukin 10, but not both cytokines, in pancreatic tissue of two patients with recently diagnosed diabetes mellitus type I.

Farilla L, Dotta F, Di Mario U, Rapoport B, McLachlan SM.

Autoimmunity. 2000 Oct;32(3):161-6.PMID: 11092695 [PubMed - indexed for MEDLINE]Related articles

Effects of prolonged exposure to pancreatic glucagon on the function, antigenicity and survival of isolated human islets.

Del Guerra S, Lupi R, Dotta F, Marselli L, Lencioni C, Santangelo C, Realacci M, Carmellini M, Mosca F, Navalesi R, Marchetti P.

Diabetes Metab Res Rev. 2000 Jul-Aug;16(4):281-6.PMID: 10934457 [PubMed - indexed for MEDLINE]Related articles

Function of pancreatic islets isolated from a type 1 diabetic patient.

Marchetti P, Dotta F, Ling Z, Lupi R, Del Guerra S, Santangelo C, Realacci M, Marselli L, Di Mario U, Navalesi R.

Diabetes Care. 2000 May;23(5):701-3. No abstract available. PMID: 10834434 [PubMed - indexed for MEDLINE]Related articlesFree article

Congenital autoimmune diabetes mellitus.

Cilio CM, Bosco S, Moretti C, Farilla L, Savignoni F, Colarizi P, Multari G, Di Mario U, Bucci G, Dotta F.

N Engl J Med. 2000 May 18;342(20):1529-31. No abstract available. Erratum in: N Engl J Med 2000 Aug 24;343(8):591. Bosco, A [corrected to Bosco, S]. PMID: 10819656 [PubMed - indexed for MEDLINE]Related articles

Autoantibody negative new onset type 1 diabetic patients lacking high risk HLA alleles in a caucasian population: are these type 1b diabetes cases?

Tiberti C, Buzzetti R, Anastasi E, Dotta F, Vasta M, Petrone A, Cervoni M, Torresi P, Vecci E, Multari G, Di Mario U.

Diabetes Metab Res Rev. 2000 Jan-Feb;16(1):8-14.PMID: 10707033 [PubMed - indexed for MEDLINE]Related articles

Expression of Reg and cytokeratin 20 during ductal cell differentiation and proliferation in a mouse model of autoimmune diabetes.

Anastasi E, Ponte E, Gradini R, Bulotta A, Sale P, Tiberti C, Okamoto H, Dotta F, Di Mario U.

Eur J Endocrinol. 1999 Dec;141(6):644-52.PMID: 10601969 [PubMed - indexed for MEDLINE]Related articlesFree article

T-cell mediated autoimmunity to the insulinoma-associated protein 2 islet tyrosine phosphatase in type 1 diabetes mellitus.

Dotta F, Dionisi S, Viglietta V, Tiberti C, Matteoli MC, Cervoni M, Bizzarri C, Marietti G, Testi M, Multari G, Lucentini L, Di Mario U.

Eur J Endocrinol. 1999 Sep;141(3):272-8.PMID: 10474125 [PubMed - indexed for MEDLINE]Related articlesFree article