PubMed

High-fat diet induces Ikkbeta and reduces insulin sensitivity in rats with low running capacity.

Bikman BT, Woodlief TL, Noland RC, Britton SL, Koch LG, Lust RM, Dohm GL, Cortright RN.

Int J Sports Med. 2009 Sep;30(9):631-5. Epub 2009 Jun 30.PMID: 19569009 [PubMed - indexed for MEDLINE]Related articles

Regulation of GLUT4 expression in denervated skeletal muscle.

Jensen EB, Zheng D, Russell RA, Bassel-Duby R, Williams RS, Olson AL, Dohm GL.

Am J Physiol Regul Integr Comp Physiol. 2009 Jun;296(6):R1820-8. Epub 2009 Mar 25.PMID: 19321702 [PubMed - indexed for MEDLINE]Related articles

Full and durable remission of type 2 diabetes? Through surgery?

Pories WJ, Dohm GL.

Surg Obes Relat Dis. 2009 Mar-Apr;5(2):285-8. Epub 2009 Jan 9. Review. No abstract available. PMID: 19250882 [PubMed - indexed for MEDLINE]Related articles

Mechanism for improved insulin sensitivity after gastric bypass surgery.

Bikman BT, Zheng D, Pories WJ, Chapman W, Pender JR, Bowden RC, Reed MA, Cortright RN, Tapscott EB, Houmard JA, Tanner CJ, Lee J, Dohm GL.

J Clin Endocrinol Metab. 2008 Dec;93(12):4656-63. Epub 2008 Sep 2.PMID: 18765510 [PubMed - indexed for MEDLINE]Related articles

Insulin sensitivity is related to fat oxidation and protein kinase C activity in children with acute burn injury.

Cree MG, Zwetsloot JJ, Herndon DN, Newcomer BR, Fram RY, Angel C, Green JM, Dohm GL, Sun D, Aarsland A, Wolfe RR.

J Burn Care Res. 2008 Jul-Aug;29(4):585-94.PMID: 18535477 [PubMed - indexed for MEDLINE]Related articles

PPAR-alpha agonism improves whole body and muscle mitochondrial fat oxidation, but does not alter intracellular fat concentrations in burn trauma children in a randomized controlled trial.

Cree MG, Newcomer BR, Herndon DN, Qian T, Sun D, Morio B, Zwetsloot JJ, Dohm GL, Fram RY, Mlcak RP, Aarsland A, Wolfe RR.

Nutr Metab (Lond). 2007 Apr 23;4:9.PMID: 17451602 [PubMed]Related articlesFree article

Artificial selection for high-capacity endurance running is protective against high-fat diet-induced insulin resistance.

Noland RC, Thyfault JP, Henes ST, Whitfield BR, Woodlief TL, Evans JR, Lust JA, Britton SL, Koch LG, Dudek RW, Dohm GL, Cortright RN, Lust RM.

Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E31-41. Epub 2007 Mar 6.PMID: 17341547 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipid metabolism, exercise and insulin action.

Bonen A, Dohm GL, van Loon LJ.

Essays Biochem. 2006;42:47-59. Review.PMID: 17144879 [PubMed - indexed for MEDLINE]Related articles

Contraction of insulin-resistant muscle normalizes insulin action in association with increased mitochondrial activity and fatty acid catabolism.

Thyfault JP, Cree MG, Zheng D, Zwetsloot JJ, Tapscott EB, Koves TR, Ilkayeva O, Wolfe RR, Muoio DM, Dohm GL.

Am J Physiol Cell Physiol. 2007 Feb;292(2):C729-39. Epub 2006 Oct 18.PMID: 17050616 [PubMed - indexed for MEDLINE]Related articlesFree article

Research opportunities provided by bariatric surgery.

Dohm GL.

Surg Obes Relat Dis. 2005 Mar-Apr;1(2):152-3. No abstract available. PMID: 16925233 [PubMed - indexed for MEDLINE]Related articles

Skeletal muscle fat oxidation is increased in African-American and white women after 10 days of endurance exercise training.

Cortright RN, Sandhoff KM, Basilio JL, Berggren JR, Hickner RC, Hulver MW, Dohm GL, Houmard JA.

Obesity (Silver Spring). 2006 Jul;14(7):1201-10.PMID: 16899801 [PubMed - indexed for MEDLINE]Related articles

Expression of genes regulating malonyl-CoA in human skeletal muscle.

Pender C, Trentadue AR, Pories WJ, Dohm GL, Houmard JA, Youngren JF.

J Cell Biochem. 2006 Oct 15;99(3):860-7.PMID: 16721829 [PubMed - indexed for MEDLINE]Related articles

Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans.

Hulver MW, Berggren JR, Carper MJ, Miyazaki M, Ntambi JM, Hoffman EP, Thyfault JP, Stevens R, Dohm GL, Houmard JA, Muoio DM.

Cell Metab. 2005 Oct;2(4):251-61.PMID: 16213227 [PubMed - indexed for MEDLINE]Related articles

Regulation of muscle GLUT4 enhancer factor and myocyte enhancer factor 2 by AMP-activated protein kinase.

Holmes BF, Sparling DP, Olson AL, Winder WW, Dohm GL.

Am J Physiol Endocrinol Metab. 2005 Dec;289(6):E1071-6. Epub 2005 Aug 16.PMID: 16105857 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.

Koves TR, Li P, An J, Akimoto T, Slentz D, Ilkayeva O, Dohm GL, Yan Z, Newgard CB, Muoio DM.

J Biol Chem. 2005 Sep 30;280(39):33588-98. Epub 2005 Aug 3.PMID: 16079133 [PubMed - indexed for MEDLINE]Related articlesFree article

Gestational diabetes is associated with depressed adiponectin levels.

Thyfault JP, Hedberg EM, Anchan RM, Thorne OP, Isler CM, Newton ER, Dohm GL, deVente JE.

J Soc Gynecol Investig. 2005 Jan;12(1):41-5.PMID: 15629670 [PubMed - indexed for MEDLINE]Related articles

The molecular mechanism linking muscle fat accumulation to insulin resistance.

Hulver MW, Dohm GL.

Proc Nutr Soc. 2004 May;63(2):375-80. Review.PMID: 15294058 [PubMed - indexed for MEDLINE]Related articles

Impaired plasma fatty acid oxidation in extremely obese women.

Thyfault JP, Kraus RM, Hickner RC, Howell AW, Wolfe RR, Dohm GL.

Am J Physiol Endocrinol Metab. 2004 Dec;287(6):E1076-81. Epub 2004 Jul 27.PMID: 15280153 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of GLUT4 gene expression during exercise.

Holmes B, Dohm GL.

Med Sci Sports Exerc. 2004 Jul;36(7):1202-6.PMID: 15235326 [PubMed - indexed for MEDLINE]Related articles

Weight loss and exercise: implications for muscle lipid metabolism and insulin action.

Berggren JR, Hulver MW, Dohm GL, Houmard JA.

Med Sci Sports Exerc. 2004 Jul;36(7):1191-5.PMID: 15235324 [PubMed - indexed for MEDLINE]Related articles

AMP kinase is not required for the GLUT4 response to exercise and denervation in skeletal muscle.

Holmes BF, Lang DB, Birnbaum MJ, Mu J, Dohm GL.

Am J Physiol Endocrinol Metab. 2004 Oct;287(4):E739-43. Epub 2004 May 27.PMID: 15165992 [PubMed - indexed for MEDLINE]Related articlesFree article

Active involvement of PKC for insulin-mediated rates of muscle protein synthesis in Zucker rats.

Fluckey JD, Cortright RN, Tapscott E, Koves T, Smith L, Pohnert S, Dohm GL.

Am J Physiol Endocrinol Metab. 2004 May;286(5):E753-8. Epub 2003 Dec 23.PMID: 14693507 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance.

Brozinick JT Jr, Roberts BR, Dohm GL.

Diabetes. 2003 Apr;52(4):935-41.PMID: 12663464 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal muscle lipid metabolism with obesity.

Hulver MW, Berggren JR, Cortright RN, Dudek RW, Thompson RP, Pories WJ, MacDonald KG, Cline GW, Shulman GI, Dohm GL, Houmard JA.

Am J Physiol Endocrinol Metab. 2003 Apr;284(4):E741-7. Epub 2002 Dec 27.PMID: 12626325 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute endurance exercise increases skeletal muscle uncoupling protein-3 gene expression in untrained but not trained humans.

Noland RC, Hickner RC, Jimenez-Linan M, Vidal-Puig A, Zheng D, Dohm GL, Cortright RN.

Metabolism. 2003 Feb;52(2):152-8.PMID: 12601624 [PubMed - indexed for MEDLINE]Related articles

Adiponectin is not altered with exercise training despite enhanced insulin action.

Hulver MW, Zheng D, Tanner CJ, Houmard JA, Kraus WE, Slentz CA, Sinha MK, Pories WJ, MacDonald KG, Dohm GL.

Am J Physiol Endocrinol Metab. 2002 Oct;283(4):E861-5.PMID: 12217905 [PubMed - indexed for MEDLINE]Related articlesFree article

Invited review: Regulation of skeletal muscle GLUT-4 expression by exercise.

Dohm GL.

J Appl Physiol. 2002 Aug;93(2):782-7. Review.PMID: 12133892 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta.

Muoio DM, MacLean PS, Lang DB, Li S, Houmard JA, Way JM, Winegar DA, Corton JC, Dohm GL, Kraus WE.

J Biol Chem. 2002 Jul 19;277(29):26089-97. Epub 2002 May 6.PMID: 12118038 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle fiber type is associated with obesity and weight loss.

Tanner CJ, Barakat HA, Dohm GL, Pories WJ, MacDonald KG, Cunningham PR, Swanson MS, Houmard JA.

Am J Physiol Endocrinol Metab. 2002 Jun;282(6):E1191-6.PMID: 12006347 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence of a malonyl-CoA-insensitive carnitine palmitoyltransferase I activity in red skeletal muscle.

Kim JY, Koves TR, Yu GS, Gulick T, Cortright RN, Dohm GL, Muoio DM.

Am J Physiol Endocrinol Metab. 2002 May;282(5):E1014-22.PMID: 11934665 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor-alpha regulates fatty acid utilization in primary human skeletal muscle cells.

Muoio DM, Way JM, Tanner CJ, Winegar DA, Kliewer SA, Houmard JA, Kraus WE, Dohm GL.

Diabetes. 2002 Apr;51(4):901-9.PMID: 11916905 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of muscle insulin resistance in obese individuals.

Dohm GL.

Int J Sport Nutr Exerc Metab. 2001 Dec;11 Suppl:S64-70. Review.PMID: 11915930 [PubMed - indexed for MEDLINE]Related articles

Long- and medium-chain fatty acid oxidation is increased in exercise-trained human skeletal muscle.

Jong-Yeon K, Hickner RC, Dohm GL, Houmard JA.

Metabolism. 2002 Apr;51(4):460-4.PMID: 11912554 [PubMed - indexed for MEDLINE]Related articles

Exercise-induced transcription of the muscle glucose transporter (GLUT 4) gene.

MacLean PS, Zheng D, Jones JP, Olson AL, Dohm GL.

Biochem Biophys Res Commun. 2002 Mar 29;292(2):409-14.PMID: 11906177 [PubMed - indexed for MEDLINE]Related articles

Effect of short-term exercise training on insulin-stimulated PI 3-kinase activity in middle-aged men.

Tanner CJ, Koves TR, Cortright RL, Pories WJ, Kim YB, Kahn BB, Dohm GL, Houmard JA.

Am J Physiol Endocrinol Metab. 2002 Jan;282(1):E147-53.PMID: 11739095 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase.

Zheng D, MacLean PS, Pohnert SC, Knight JB, Olson AL, Winder WW, Dohm GL.

J Appl Physiol. 2001 Sep;91(3):1073-83.PMID: 11509501 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased protein kinase C theta in skeletal muscle of diabetic patients.

Itani SI, Pories WJ, Macdonald KG, Dohm GL.

Metabolism. 2001 May;50(5):553-7.PMID: 11319716 [PubMed - indexed for MEDLINE]Related articles

Substrate utilization during exercise in formerly morbidly obese women.

Guesbeck NR, Hickey MS, MacDonald KG, Pories WJ, Harper I, Ravussin E, Dohm GL, Houmard JA.

J Appl Physiol. 2001 Mar;90(3):1007-12.PMID: 11181612 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle glucose transporter (GLUT 4) gene expression during exercise.

MacLean PS, Zheng D, Dohm GL.

Exerc Sport Sci Rev. 2000 Oct;28(4):148-52. Review.PMID: 11064847 [PubMed - indexed for MEDLINE]Related articles

Lipid oxidation is reduced in obese human skeletal muscle.

Kim JY, Hickner RC, Cortright RL, Dohm GL, Houmard JA.

Am J Physiol Endocrinol Metab. 2000 Nov;279(5):E1039-44.PMID: 11052958 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of respiratory muscle training on GLUT-4 in the sheep diaphragm.

Bhandari A, Xia Y, Cortright R, Dohm GL, Bazzy AR.

Med Sci Sports Exerc. 2000 Aug;32(8):1406-11.PMID: 10949006 [PubMed - indexed for MEDLINE]Related articles

Involvement of protein kinase C in human skeletal muscle insulin resistance and obesity.

Itani SI, Zhou Q, Pories WJ, MacDonald KG, Dohm GL.

Diabetes. 2000 Aug;49(8):1353-8.PMID: 10923637 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin stimulation of muscle protein synthesis in obese Zucker rats is not via a rapamycin-sensitive pathway.

Fluckey JD, Pohnert SC, Boyd SG, Cortright RN, Trappe TA, Dohm GL.

Am J Physiol Endocrinol Metab. 2000 Jul;279(1):E182-7.PMID: 10893338 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase C modulates insulin action in human skeletal muscle.

Cortright RN, Azevedo JL Jr, Zhou Q, Sinha M, Pories WJ, Itani SI, Dohm GL.

Am J Physiol Endocrinol Metab. 2000 Mar;278(3):E553-62.PMID: 10710511 [PubMed - indexed for MEDLINE]Related articlesFree article

Dephosphorylation increases insulin-stimulated receptor kinase activity in skeletal muscle of obese Zucker rats.

Zhou Q, Dolan PL, Dohm GL.

Mol Cell Biochem. 1999 Apr;194(1-2):209-16.PMID: 10391142 [PubMed - indexed for MEDLINE]Related articles

Effect of aging on response to exercise training in humans: skeletal muscle GLUT-4 and insulin sensitivity.

Cox JH, Cortright RN, Dohm GL, Houmard JA.

J Appl Physiol. 1999 Jun;86(6):2019-25.PMID: 10368369 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of hyperinsulinemia on myosin heavy chain gene regulation.

Houmard JA, O'Neill DS, Zheng D, Hickey MS, Dohm GL.

J Appl Physiol. 1999 Jun;86(6):1828-32.PMID: 10368345 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin opposes insulin's effects on fatty acid partitioning in muscles isolated from obese ob/ob mice.

Muoio DM, Dohm GL, Tapscott EB, Coleman RA.

Am J Physiol. 1999 May;276(5 Pt 1):E913-21.PMID: 10329986 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of obesity and stable weight reduction on UCP2 and UCP3 gene expression in humans.

Vidal-Puig A, Rosenbaum M, Considine RC, Leibel RL, Dohm GL, Lowell BB.

Obes Res. 1999 Mar;7(2):133-40.PMID: 10102249 [PubMed - indexed for MEDLINE]Related articles

Effect of endurance exercise on myosin heavy chain gene regulation in human skeletal muscle.

O'Neill DS, Zheng D, Anderson WK, Dohm GL, Houmard JA.

Am J Physiol. 1999 Feb;276(2 Pt 2):R414-9.PMID: 9950919 [PubMed - indexed for MEDLINE]Related articlesFree article