PubMed

An engineered zinc finger protein reveals a role for the insulin VNTR in the regulation of the insulin and adjacent IGF2 genes.

Ferguson LA, Docherty HM, MacKenzie AE, Docherty K.

FEBS Lett. 2009 Oct 6;583(19):3181-6. Epub 2009 Sep 5.PMID: 19733567 [PubMed - indexed for MEDLINE]Related articles

Chemically-resolved volatility measurements of organic aerosol fom different sources.

Huffman JA, Docherty KS, Mohr C, Cubison MJ, Ulbrich IM, Ziemann PJ, Onasch TB, Jimenez JL.

Environ Sci Technol. 2009 Jul 15;43(14):5351-7.PMID: 19708365 [PubMed - indexed for MEDLINE]Related articles

Pancreatic stellate cells can form new beta-like cells.

Docherty K.

Biochem J. 2009 Jun 26;421(2):e1-4.PMID: 19552623 [PubMed - indexed for MEDLINE]Related articles

Combinatorial transcription factor regulation of the cyclic AMP-response element on the Pgc-1alpha promoter in white 3T3-L1 and brown HIB-1B preadipocytes.

Karamitri A, Shore AM, Docherty K, Speakman JR, Lomax MA.

J Biol Chem. 2009 Jul 31;284(31):20738-52. Epub 2009 Jun 2.PMID: 19491401 [PubMed - indexed for MEDLINE]Related articles

Characterization of primary organic aerosol emissions from meat cooking, trash burning, and motor vehicles with high-resolution aerosol mass spectrometry and comparison with ambient and chamber observations.

Mohr C, Huffman A, Cubison MJ, Aiken AC, Docherty KS, Kimmel JR, Ulbrich IM, Hannigan M, Jimenez JL.

Environ Sci Technol. 2009 Apr 1;43(7):2443-9.PMID: 19452899 [PubMed - indexed for MEDLINE]Related articles

Identification of adjacent binding sites for the YY1 and E4BP4 transcription factors in the ovine PrP (Prion) gene promoter.

Burgess ST, Shen C, Ferguson LA, O'Neill GT, Docherty K, Hunter N, Goldmann W.

J Biol Chem. 2009 Mar 13;284(11):6716-24. Epub 2009 Jan 7.PMID: 19129193 [PubMed - indexed for MEDLINE]Related articles

Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells.

Bernardo AS, Cho CH, Mason S, Docherty HM, Pedersen RA, Vallier L, Docherty K.

Stem Cells. 2009 Feb;27(2):341-51.PMID: 19056911 [PubMed - indexed for MEDLINE]Related articles

Apportionment of primary and secondary organic aerosols in southern California during the 2005 study of organic aerosols in riverside (SOAR-1).

Docherty KS, Stone EA, Ulbrich IM, DeCarlo PF, Snyder DC, Schauer JJ, Peltier RE, Weber RJ, Murphy SM, Seinfeld JH, Grover BD, Eatough DJ, Jimenez JL.

Environ Sci Technol. 2008 Oct 15;42(20):7655-62.PMID: 18983089 [PubMed - indexed for MEDLINE]Related articles

Pancreatic transcription factors and their role in the birth, life and survival of the pancreatic beta cell.

Bernardo AS, Hay CW, Docherty K.

Mol Cell Endocrinol. 2008 Nov 6;294(1-2):1-9. Epub 2008 Jul 22. Review.PMID: 18687378 [PubMed - indexed for MEDLINE]Related articles

O/C and OM/OC ratios of primary, secondary, and ambient organic aerosols with high-resolution time-of-flight aerosol mass spectrometry.

Aiken AC, Decarlo PF, Kroll JH, Worsnop DR, Huffman JA, Docherty KS, Ulbrich IM, Mohr C, Kimmel JR, Sueper D, Sun Y, Zhang Q, Trimborn A, Northway M, Ziemann PJ, Canagaratna MR, Onasch TB, Alfarra MR, Prevot AS, Dommen J, Duplissy J, Metzger A, Baltensperger U, Jimenez JL.

Environ Sci Technol. 2008 Jun 15;42(12):4478-85.PMID: 18605574 [PubMed - indexed for MEDLINE]Related articles

Stem cells and metabolic diseases.

Bernardo AS, Docherty K.

Biochem Soc Trans. 2008 Jun;36(Pt 3):363-5. Review.PMID: 18481959 [PubMed - indexed for MEDLINE]Related articles

Embryonic stem cell therapy for diabetes mellitus.

Docherty K, Bernardo AS, Vallier L.

Semin Cell Dev Biol. 2007 Dec;18(6):827-38. Epub 2007 Sep 11. Review.PMID: 17959396 [PubMed - indexed for MEDLINE]Related articles

C/EBPbeta reprograms white 3T3-L1 preadipocytes to a Brown adipocyte pattern of gene expression.

Karamanlidis G, Karamitri A, Docherty K, Hazlerigg DG, Lomax MA.

J Biol Chem. 2007 Aug 24;282(34):24660-9. Epub 2007 Jun 21.PMID: 17584738 [PubMed - indexed for MEDLINE]Related articlesFree article

ATF-2 stimulates the human insulin promoter through the conserved CRE2 sequence.

Hay CW, Ferguson LA, Docherty K.

Biochim Biophys Acta. 2007 Feb;1769(2):79-91. Epub 2007 Jan 28.PMID: 17337306 [PubMed - indexed for MEDLINE]Related articles

Field-deployable, high-resolution, time-of-flight aerosol mass spectrometer.

DeCarlo PF, Kimmel JR, Trimborn A, Northway MJ, Jayne JT, Aiken AC, Gonin M, Fuhrer K, Horvath T, Docherty KS, Worsnop DR, Jimenez JL.

Anal Chem. 2006 Dec 15;78(24):8281-9.PMID: 17165817 [PubMed]Related articles

Comparative analysis of insulin gene promoters: implications for diabetes research.

Hay CW, Docherty K.

Diabetes. 2006 Dec;55(12):3201-13. Review.PMID: 17130462 [PubMed - indexed for MEDLINE]Related articlesFree article

Biodegradability of imidazolium and pyridinium ionic liquids by an activated sludge microbial community.

Docherty KM, Dixon JK, Kulpa CF Jr.

Biodegradation. 2007 Aug;18(4):481-93. Epub 2006 Nov 8.PMID: 17091344 [PubMed - indexed for MEDLINE]Related articles

Dissolved organic matter concentration and quality influences upon structure and function of freshwater microbial communities.

Docherty KM, Young KC, Maurice PA, Bridgham SD.

Microb Ecol. 2006 Oct;52(3):378-88. Epub 2006 Jun 10.PMID: 16767520 [PubMed - indexed for MEDLINE]Related articles

Presence of endocrine and exocrine markers in EGFP-positive cells from the developing pancreas of a nestin/EGFP mouse.

Bernardo AS, Barrow J, Hay CW, McCreath K, Kind AJ, Schnieke AE, Colman A, Hart AW, Docherty K.

Mol Cell Endocrinol. 2006 Jul 11;253(1-2):14-21. Epub 2006 May 12.PMID: 16698177 [PubMed - indexed for MEDLINE]Related articles

Reaction of oleic acid particles with NO3 radicals: Products, mechanism, and implications for radical-initiated organic aerosol oxidation.

Docherty KS, Ziemann PJ.

J Phys Chem A. 2006 Mar 16;110(10):3567-77.PMID: 16526637 [PubMed]Related articles

Transcription factor cycling on the insulin promoter.

Barrow J, Hay CW, Ferguson LA, Docherty HM, Docherty K.

FEBS Lett. 2006 Jan 23;580(2):711-5. Epub 2005 Dec 28.PMID: 16412423 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1 stimulates human insulin promoter activity in part through cAMP-responsive elements that lie upstream and downstream of the transcription start site.

Hay CW, Sinclair EM, Bermano G, Durward E, Tadayyon M, Docherty K.

J Endocrinol. 2005 Aug;186(2):353-65.PMID: 16079261 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene symbol: IPF1. Disease: MODY 4.

Cockburn BN, Bermano G, Boodram LL, Teelucksingh S, Tsuchiya T, Mahabir D, Allan AB, Stein R, Docherty K, Bell GI.

Hum Genet. 2005 May;116(6):538. No abstract available. PMID: 15991313 [PubMed - indexed for MEDLINE]Related articles

Contributions of organic peroxides to secondary aerosol formed from reactions of monoterpenes with O3.

Docherty KS, Wu W, Lim YB, Ziemann PJ.

Environ Sci Technol. 2005 Jun 1;39(11):4049-59.PMID: 15984782 [PubMed - indexed for MEDLINE]Related articles

Relative contribution of PDX-1, MafA and E47/beta2 to the regulation of the human insulin promoter.

Docherty HM, Hay CW, Ferguson LA, Barrow J, Durward E, Docherty K.

Biochem J. 2005 Aug 1;389(Pt 3):813-20.PMID: 15862113 [PubMed - indexed for MEDLINE]Related articlesFree article

Purification and Characterization of a Population of EGFP-Expressing Cells from the Developing Pancreas of a Neurogenin3/EGFP Transgenic Mouse.

Barrow J, Bernardo AS, Hay CW, Blaylock M, Duncan L, Mackenzie A, McCreath K, Kind AJ, Schnieke AE, Colman A, Hart AW, Docherty K.

Organogenesis. 2005 Jan;2(1):22-7.PMID: 19521525 [PubMed - in process]Related articlesFree article

Gas chromatography of trimethylsilyl derivatives of alpha-methoxyalkyl hydroperoxides formed in alkene-O3 reactions.

Docherty KS, Kumboonlert K, Lee IJ, Ziemann PJ.

J Chromatogr A. 2004 Mar 12;1029(1-2):205-15.PMID: 15032366 [PubMed - indexed for MEDLINE]Related articles

Insulin promoter factor-1 mutations and diabetes in Trinidad: identification of a novel diabetes-associated mutation (E224K) in an Indo-Trinidadian family.

Cockburn BN, Bermano G, Boodram LL, Teelucksingh S, Tsuchiya T, Mahabir D, Allan AB, Stein R, Docherty K, Bell GI.

J Clin Endocrinol Metab. 2004 Feb;89(2):971-8.PMID: 14764823 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced expression of a furin-cleavable proinsulin.

Hay CW, Docherty K.

J Mol Endocrinol. 2003 Dec;31(3):597-607.PMID: 14664719 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of water temperature on the GABAergic and reproductive systems in female and male goldfish (Carassius auratus).

Fraser EJ, Bosma PT, Trudeau VL, Docherty K.

Gen Comp Endocrinol. 2002 Feb 1;125(2):163-75.PMID: 11884062 [PubMed - indexed for MEDLINE]Related articles

Secretion of bioactive human insulin following plasmid-mediated gene transfer to non-neuroendocrine cell lines, primary cultures and rat skeletal muscle in vivo.

Shaw JA, Delday MI, Hart AW, Docherty HM, Maltin CA, Docherty K.

J Endocrinol. 2002 Mar;172(3):653-72.PMID: 11874714 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth and development of the islets of Langerhans: implications for the treatment of diabetes mellitus.

Docherty K.

Curr Opin Pharmacol. 2001 Dec;1(6):641-50. Review.PMID: 11757821 [PubMed - indexed for MEDLINE]Related articles

Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta cell identity and function.

McKinnon CM, Docherty K.

Diabetologia. 2001 Oct;44(10):1203-14. Review.PMID: 11692168 [PubMed - indexed for MEDLINE]Related articles

Phosphorylation-dependent nucleocytoplasmic shuttling of pancreatic duodenal homeobox-1.

Elrick LJ, Docherty K.

Diabetes. 2001 Oct;50(10):2244-52.PMID: 11574405 [PubMed - indexed for MEDLINE]Related articlesFree article

On-line, inlet-based trimethylsilyl derivatization for gas chromatography of mono- and dicarboxylic acids.

Docherty KS, Zieman PJ.

J Chromatogr A. 2001 Jul 6;921(2):265-75.PMID: 11471810 [PubMed - indexed for MEDLINE]Related articles

Association of prohormone convertase 3 with membrane lipid rafts.

Blázquez M, Docherty K, Shennan KI.

J Mol Endocrinol. 2001 Aug;27(1):107-16.PMID: 11463581 [PubMed - indexed for MEDLINE]Related articlesFree article

Sexually dimorphic expression of glutamate decarboxylase mRNA in the hypothalamus of the deep sea armed grenadier, Coryphaenoides (Nematonurus) armatus.

Trudeau VL, Bosma PT, Collins M, Priede IG, Docherty K.

Brain Behav Evol. 2000 Nov;56(5):269-75.PMID: 11251319 [PubMed - indexed for MEDLINE]Related articles

Sex steroid regulation of glutamate decarboxylase mRNA expression in goldfish brain is sexually dimorphic.

Bosma PT, Blázquez M, Fraser EJ, Schulz RW, Docherty K, Trudeau VL.

J Neurochem. 2001 Feb;76(4):945-56.PMID: 11181814 [PubMed - indexed for MEDLINE]Related articles

Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes

Macfarlane WM, Frayling TM, Ellard S, Evans JC, Allen LI, Bulman MP, Ayers S, Shepherd M, Clark P, Millward A, Demaine A, Wilken T, Docherty K, Hattersley AT.

J Clin Invest. 2000 Sep;106(5):717. No abstract available. PMID: 10974025 [PubMed - as supplied by publisher]Related articles

Processing of synthetic pro-islet amyloid polypeptide (proIAPP) 'amylin' by recombinant prohormone convertase enzymes, PC2 and PC3, in vitro.

Higham CE, Hull RL, Lawrie L, Shennan KI, Morris JF, Birch NP, Docherty K, Clark A.

Eur J Biochem. 2000 Aug;267(16):4998-5004.PMID: 10931181 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of the membrane lipid bilayer in sorting prohormone convertase 2 into the regulated secretory pathway.

Blázquez M, Thiele C, Huttner WB, Docherty K, Shennan KI.

Biochem J. 2000 Aug 1;349 Pt 3:843-52.PMID: 10903147 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for recognition of novel islet T cell antigens by granule-specific T cell lines from new onset type 1 diabetic patients.

Tree TI, O'Byrne D, Tremble JM, MacFarlane WM, Haskins K, James RF, Docherty K, Hutton JC, Banga JP.

Clin Exp Immunol. 2000 Jul;121(1):100-5.PMID: 10886245 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose modulation of insulin mRNA levels is dependent on transcription factor PDX-1 and occurs independently of changes in intracellular Ca2+.

Macfarlane WM, Shepherd RM, Cosgrove KE, James RF, Dunne MJ, Docherty K.

Diabetes. 2000 Mar;49(3):418-23.PMID: 10868963 [PubMed - indexed for MEDLINE]Related articlesFree article

Sulfonylurea receptor 1 and Kir6.2 expression in the novel human insulin-secreting cell line NES2Y.

Macfarlane WM, O'Brien RE, Barnes PD, Shepherd RM, Cosgrove KE, Lindley KJ, Aynsley-Green A, James RF, Docherty K, Dunne MJ.

Diabetes. 2000 Jun;49(6):953-60.PMID: 10866047 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth and development of the islets of langerhans: implications for the treatment of diabetes. A special section consisting of proceedings from the journal of molecular endocrinology symposium at the 190th meeting of the society for endocrinology, london, 8 november 1999

Docherty K.

J Mol Endocrinol. 2000 Jun;24(3):295. No abstract available. PMID: 10828821 [PubMed - as supplied by publisher]Related articlesFree article

Glucose regulates islet amyloid polypeptide gene transcription in a PDX1- and calcium-dependent manner.

Macfarlane WM, Campbell SC, Elrick LJ, Oates V, Bermano G, Lindley KJ, Aynsley-Green A, Dunne MJ, James RF, Docherty K.

J Biol Chem. 2000 May 19;275(20):15330-5.PMID: 10748090 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibitory effect of pax4 on the human insulin and islet amyloid polypeptide (IAPP) promoters.

Campbell SC, Cragg H, Elrick LJ, Macfarlane WM, Shennan KI, Docherty K.

FEBS Lett. 1999 Dec 10;463(1-2):53-7.PMID: 10601637 [PubMed - indexed for MEDLINE]Related articles

Insulin stimulates pancreatic-duodenal homoeobox factor-1 (PDX1) DNA-binding activity and insulin promoter activity in pancreatic beta cells.

Wu H, MacFarlane WM, Tadayyon M, Arch JR, James RF, Docherty K.

Biochem J. 1999 Dec 15;344 Pt 3:813-8.PMID: 10585868 [PubMed - indexed for MEDLINE]Related articlesFree article

Engineering a glucose-responsive human insulin-secreting cell line from islets of Langerhans isolated from a patient with persistent hyperinsulinemic hypoglycemia of infancy.

MacFarlane WM, Chapman JC, Shepherd RM, Hashmi MN, Kamimura N, Cosgrove KE, O'Brien RE, Barnes PD, Hart AW, Docherty HM, Lindley KJ, Aynsley-Green A, James RF, Docherty K, Dunne MJ.

J Biol Chem. 1999 Nov 26;274(48):34059-66.PMID: 10567373 [PubMed - indexed for MEDLINE]Related articlesFree article

Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes.

Macfarlane WM, Frayling TM, Ellard S, Evans JC, Allen LI, Bulman MP, Ayres S, Shepherd M, Clark P, Millward A, Demaine A, Wilkin T, Docherty K, Hattersley AT.

J Clin Invest. 1999 Nov;104(9):R33-9.PMID: 10545530 [PubMed - indexed for MEDLINE]Related articlesFree article