PubMed

HLA class I supertypes in type 1 diabetic children in an urban children's hospital.

Antal Z, Jarchum I, DiLorenzo TP.

Ann N Y Acad Sci. 2008 Dec;1150:86-9.PMID: 19120273 [PubMed - indexed for MEDLINE]Related articlesFree article

Lentivectors encoding immunosuppressive proteins genetically engineer pancreatic beta-cells to correct diabetes in allogeneic mice.

Kojaoghlanian T, Joseph A, Follenzi A, Zheng JH, Leiser M, Fleischer N, Horwitz MS, DiLorenzo TP, Goldstein H.

Gene Ther. 2009 Mar;16(3):340-8. Epub 2008 Dec 25.PMID: 19112449 [PubMed - in process]Related articles

Efficient culture of CD8(+) T cells from the islets of NOD mice and their use for the study of autoreactive specificities.

Jarchum I, Takaki T, DiLorenzo TP.

J Immunol Methods. 2008 Nov 30;339(1):66-73. Epub 2008 Sep 7.PMID: 18782577 [PubMed - indexed for MEDLINE]Related articles

Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells.

Chaparro RJ, Burton AR, Serreze DV, Vignali DA, DiLorenzo TP.

J Immunol Methods. 2008 Jun 1;335(1-2):106-15. Epub 2008 Apr 8.PMID: 18439618 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice.

Mukhopadhaya A, Hanafusa T, Jarchum I, Chen YG, Iwai Y, Serreze DV, Steinman RM, Tarbell KV, DiLorenzo TP.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6374-9. Epub 2008 Apr 22.PMID: 18430797 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of novel IGRP epitopes targeted in type 1 diabetes patients.

Jarchum I, Nichol L, Trucco M, Santamaria P, DiLorenzo TP.

Clin Immunol. 2008 Jun;127(3):359-65. Epub 2008 Mar 20.PMID: 18358785 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural genomics of protein phosphatases.

Almo SC, Bonanno JB, Sauder JM, Emtage S, Dilorenzo TP, Malashkevich V, Wasserman SR, Swaminathan S, Eswaramoorthy S, Agarwal R, Kumaran D, Madegowda M, Ragumani S, Patskovsky Y, Alvarado J, Ramagopal UA, Faber-Barata J, Chance MR, Sali A, Fiser A, Zhang ZY, Lawrence DS, Burley SK.

J Struct Funct Genomics. 2007 Sep;8(2-3):121-40. Epub 2007 Dec 5. Review.PMID: 18058037 [PubMed - indexed for MEDLINE]Related articles

Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.

Chattopadhyay K, Ramagopal UA, Mukhopadhaya A, Malashkevich VN, Dilorenzo TP, Brenowitz M, Nathenson SG, Almo SC.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19452-7. Epub 2007 Nov 26.PMID: 18040044 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice.

Jarchum I, Baker JC, Yamada T, Takaki T, Marron MP, Serreze DV, DiLorenzo TP.

Diabetes. 2007 Oct;56(10):2551-60. Epub 2007 Jul 9.PMID: 17620420 [PubMed - indexed for MEDLINE]Related articlesFree article

"Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes.

Serreze DV, Marron MP, Dilorenzo TP.

Ann N Y Acad Sci. 2007 Apr;1103:103-11. Epub 2007 Mar 21.PMID: 17376821 [PubMed - indexed for MEDLINE]Related articles

T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface.

Cao E, Zang X, Ramagopal UA, Mukhopadhaya A, Fedorov A, Fedorov E, Zencheck WD, Lary JW, Cole JL, Deng H, Xiao H, Dilorenzo TP, Allison JP, Nathenson SG, Almo SC.

Immunity. 2007 Mar;26(3):311-21.PMID: 17363302 [PubMed - indexed for MEDLINE]Related articles

Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator.

Forestier C, Takaki T, Molano A, Im JS, Baine I, Jerud ES, Illarionov P, Ndonye R, Howell AR, Santamaria P, Besra GS, Dilorenzo TP, Porcelli SA.

J Immunol. 2007 Feb 1;178(3):1415-25.PMID: 17237389 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes.

Takaki T, Marron MP, Mathews CE, Guttmann ST, Bottino R, Trucco M, DiLorenzo TP, Serreze DV.

J Immunol. 2006 Mar 1;176(5):3257-65.PMID: 16493087 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural analysis of H2-Db class I molecules containing two different allelic forms of the type 1 diabetes susceptibility factor beta-2 microglobulin: implications for the mechanism underlying variations in antigen presentation.

Roden MM, Brims DR, Fedorov AA, DiLorenzo TP, Almo SC, Nathenson SG.

Mol Immunol. 2006 Mar;43(9):1370-8. Epub 2005 Oct 17.PMID: 16229893 [PubMed - indexed for MEDLINE]Related articles

Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.

Han B, Serra P, Yamanouchi J, Amrani A, Elliott JF, Dickie P, Dilorenzo TP, Santamaria P.

J Clin Invest. 2005 Jul;115(7):1879-87. Epub 2005 Jun 2.PMID: 15937548 [PubMed - indexed for MEDLINE]Related articlesFree article

The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice.

DiLorenzo TP, Serreze DV.

Immunol Rev. 2005 Apr;204:250-63. Review. Erratum in: Immunol Rev. 2005 Aug;206:336. PMID: 15790363 [PubMed - indexed for MEDLINE]Related articles

Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase.

Lieberman SM, Takaki T, Han B, Santamaria P, Serreze DV, DiLorenzo TP.

J Immunol. 2004 Dec 1;173(11):6727-34.PMID: 15557165 [PubMed - indexed for MEDLINE]Related articlesFree article

Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4.

Takaki T, Lieberman SM, Holl TM, Han B, Santamaria P, Serreze DV, DiLorenzo TP.

J Immunol. 2004 Aug 15;173(4):2530-41.PMID: 15294969 [PubMed - indexed for MEDLINE]Related articlesFree article

MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice.

Serreze DV, Holl TM, Marron MP, Graser RT, Johnson EA, Choisy-Rossi C, Slattery RM, Lieberman SM, DiLorenzo TP.

J Immunol. 2004 Jan 15;172(2):871-9.PMID: 14707058 [PubMed - indexed for MEDLINE]Related articlesFree article

A comprehensive guide to antibody and T-cell responses in type 1 diabetes.

Lieberman SM, DiLorenzo TP.

Tissue Antigens. 2003 Nov;62(5):359-77. Review.PMID: 14617043 [PubMed - indexed for MEDLINE]Related articles

Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

Lieberman SM, Evans AM, Han B, Takaki T, Vinnitskaya Y, Caldwell JA, Serreze DV, Shabanowitz J, Hunt DF, Nathenson SG, Santamaria P, DiLorenzo TP.

Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8384-8. Epub 2003 Jun 18.PMID: 12815107 [PubMed - indexed for MEDLINE]Related articlesFree article

During the early prediabetic period in NOD mice, the pathogenic CD8(+) T-cell population comprises multiple antigenic specificities.

DiLorenzo TP, Lieberman SM, Takaki T, Honda S, Chapman HD, Santamaria P, Serreze DV, Nathenson SG.

Clin Immunol. 2002 Dec;105(3):332-41.PMID: 12498815 [PubMed - indexed for MEDLINE]Related articles

Immunobiological analysis of TCR single-chain transgenic mice reveals new possibilities for interaction between CDR3alpha and an antigenic peptide bound to MHC class I.

Zhang W, Honda S, Wang F, DiLorenzo TP, Kalergis AM, Ostrov DA, Nathenson SG.

J Immunol. 2001 Oct 15;167(8):4396-404.PMID: 11591764 [PubMed - indexed for MEDLINE]Related articlesFree article

Hapten addition to an MHC class I-binding peptide causes substantial adjustments of the TCR structure of the responding CD8(+) T cells.

Honda S, Zhang W, Kalergis AM, DiLorenzo TP, Wang F, Nathenson SG.

J Immunol. 2001 Oct 15;167(8):4276-85.PMID: 11591750 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool.

Serreze DV, Johnson EA, Chapman HD, Graser RT, Marron MP, DiLorenzo TP, Silveira P, Yoshimura Y, Nathenson SG, Joyce S.

Diabetes. 2001 Sep;50(9):1992-2000.PMID: 11522664 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions.

Graser RT, DiLorenzo TP, Wang F, Christianson GJ, Chapman HD, Roopenian DC, Nathenson SG, Serreze DV.

J Immunol. 2000 Apr 1;164(7):3913-8.PMID: 10725754 [PubMed - indexed for MEDLINE]Related articlesFree article

Binding of longer peptides to the H-2Kb heterodimer is restricted to peptides extended at their C terminus: refinement of the inherent MHC class I peptide binding criteria.

Hörig H, Young AC, Papadopoulos NJ, DiLorenzo TP, Nathenson SG.

J Immunol. 1999 Oct 15;163(8):4434-41.PMID: 10510385 [PubMed - indexed for MEDLINE]Related articlesFree article

Single amino acid replacements in an antigenic peptide are sufficient to alter the TCR V beta repertoire of the responding CD8+ cytotoxic lymphocyte population.

Kalergis AM, Ono T, Wang F, DiLorenzo TP, Honda S, Nathenson SG.

J Immunol. 1999 Jun 15;162(12):7263-70.PMID: 10358174 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevation of the epidermal growth factor receptor and dependent signaling in human papillomavirus-infected laryngeal papillomas.

Johnston D, Hall H, DiLorenzo TP, Steinberg BM.

Cancer Res. 1999 Feb 15;59(4):968-74.PMID: 10029092 [PubMed - indexed for MEDLINE]Related articlesFree article

Alterations in TCR-MHC contacts subsequent to cross-recognition of class I MHC and singly substituted peptide variants.

Ono T, DiLorenzo TP, Wang F, Kalergis AM, Nathenson SG.

J Immunol. 1998 Nov 15;161(10):5454-63.PMID: 9820521 [PubMed - indexed for MEDLINE]Related articlesFree article

Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement.

DiLorenzo TP, Graser RT, Ono T, Christianson GJ, Chapman HD, Roopenian DC, Nathenson SG, Serreze DV.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12538-43.PMID: 9770521 [PubMed - indexed for MEDLINE]Related articlesFree article

On defining the rules for interactions between the T cell receptor and its ligand: a critical role for a specific amino acid residue of the T cell receptor beta chain.

Wang F, Ono T, Kalergis AM, Zhang W, DiLorenzo TP, Lim K, Nathenson SG.

Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5217-22.PMID: 9560256 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for the separate regulation of the human papillomavirus type 11 E7 and E6 promoters by Viral cis sequences near the E6 promoter.

DiLorenzo TP, Chen D, Zhang P, Steinberg BM.

Virology. 1998 Mar 30;243(1):130-9.PMID: 9527922 [PubMed - indexed for MEDLINE]Related articles

A possible role for human papillomaviruses in head and neck cancer.

Steinberg BM, DiLorenzo TP.

Cancer Metastasis Rev. 1996 Mar;15(1):91-112. Review.PMID: 8842481 [PubMed - indexed for MEDLINE]Related articles

Differential regulation of human papillomavirus type 6 and 11 early promoters in cultured cells derived from laryngeal papillomas.

DiLorenzo TP, Steinberg BM.

J Virol. 1995 Nov;69(11):6865-72.PMID: 7474101 [PubMed - indexed for MEDLINE]Related articlesFree article

Human papillomavirus type 6a DNA in the lung carcinoma of a patient with recurrent laryngeal papillomatosis is characterized by a partial duplication.

DiLorenzo TP, Tamsen A, Abramson AL, Steinberg BM.

J Gen Virol. 1992 Feb;73 ( Pt 2):423-8.PMID: 1311363 [PubMed - indexed for MEDLINE]Related articlesFree article

Replication and persistence of HPV DNA in cultured cells derived from laryngeal papillomas.

DiLorenzo TP, Taichman LB, Steinberg BM.

Virology. 1992 Jan;186(1):148-53.PMID: 1309272 [PubMed - indexed for MEDLINE]Related articles

In vitro modulation of human laryngeal papilloma cell differentiation by retinoic acid.

Reppucci AD, DiLorenzo TP, Abramson AL, Steinberg BM.

Otolaryngol Head Neck Surg. 1991 Oct;105(4):528-32.PMID: 1662346 [PubMed - indexed for MEDLINE]Related articles

Retinoic acid regulates, in vitro, the two normal pathways of differentiation of human laryngeal keratinocytes.

Mendelsohn MG, Dilorenzo TP, Abramson AL, Steinberg BM.

In Vitro Cell Dev Biol. 1991 Feb;27A(2):137-41.PMID: 1708372 [PubMed - indexed for MEDLINE]Related articles

Laryngeal keratinocytes show variable inhibition of replication by TGF-beta.

DiLorenzo TP, Steinberg BM.

J Cell Sci. 1990 May;96 ( Pt 1):115-9.PMID: 2373737 [PubMed - indexed for MEDLINE]Related articlesFree article

Is papillomavirus detectable in the plume of laser-treated laryngeal papilloma?

Abramson AL, DiLorenzo TP, Steinberg BM.

Arch Otolaryngol Head Neck Surg. 1990 May;116(5):604-7.PMID: 2158332 [PubMed - indexed for MEDLINE]Related articles

Identification of DNA-protein interactions and enhancer activity at the 5' end of the upstream regulatory region in human papillomavirus type 11.

Auborn KJ, Galli RL, Dilorenzo TP, Steinberg BM.

Virology. 1989 May;170(1):123-30.PMID: 2541536 [PubMed - indexed for MEDLINE]Related articles