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Preliminary report: pharmacologic 11beta-hydroxysteroid dehydrogenase type 1 inhibition increases hepatic fat oxidation in vivo and expression of related genes in rats fed an obesogenic diet.

Berthiaume M, Laplante M, Festuccia WT, Berger JP, Thieringer R, Deshaies Y.

Metabolism. 2009 Sep 17. [Epub ahead of print]PMID: 19766266 [PubMed - as supplied by publisher]Related articles

Rosiglitazone-induced heart remodelling is associated with enhanced turnover of myofibrillar protein and mTOR activation.

Festuccia WT, Laplante M, Brûlé S, Houde VP, Achouba A, Lachance D, Pedrosa ML, Silva ME, Guerra-Sá R, Couet J, Arsenault M, Marette A, Deshaies Y.

J Mol Cell Cardiol. 2009 Jul;47(1):85-95. Epub 2009 May 3.PMID: 19397913 [PubMed - in process]Related articles

Association of OSBPL11 gene polymorphisms with cardiovascular disease risk factors in obesity.

Bouchard L, Faucher G, Tchernof A, Deshaies Y, Marceau S, Lescelleur O, Biron S, Bouchard C, Pérusse L, Vohl MC.

Obesity (Silver Spring). 2009 Jul;17(7):1466-72. Epub 2009 Mar 26.PMID: 19325544 [PubMed - indexed for MEDLINE]Related articles

Additive action of 11beta-HSD1 inhibition and PPAR-gamma agonism on hepatic steatosis and triglyceridemia in diet-induced obese rats.

Berthiaume M, Laplante M, Festuccia WT, Berger JP, Thieringer R, Deshaies Y.

Int J Obes (Lond). 2009 May;33(5):601-4. Epub 2009 Feb 17.PMID: 19223847 [PubMed - in process]Related articles

The PPARgamma agonist rosiglitazone enhances rat brown adipose tissue lipogenesis from glucose without altering glucose uptake.

Festuccia WT, Blanchard PG, Turcotte V, Laplante M, Sariahmetoglu M, Brindley DN, Richard D, Deshaies Y.

Am J Physiol Regul Integr Comp Physiol. 2009 May;296(5):R1327-35. Epub 2009 Feb 11.PMID: 19211718 [PubMed - indexed for MEDLINE]Related articles

Depot-specific effects of the PPARgamma agonist rosiglitazone on adipose tissue glucose uptake and metabolism.

Festuccia WT, Blanchard PG, Turcotte V, Laplante M, Sariahmetoglu M, Brindley DN, Deshaies Y.

J Lipid Res. 2009 Jun;50(6):1185-94. Epub 2009 Feb 5.PMID: 19201733 [PubMed - indexed for MEDLINE]Related articles

Tissue-specific postprandial clearance is the major determinant of PPARgamma-induced triglyceride lowering in the rat.

Laplante M, Festuccia WT, Soucy G, Blanchard PG, Renaud A, Berger JP, Olivecrona G, Deshaies Y.

Am J Physiol Regul Integr Comp Physiol. 2009 Jan;296(1):R57-66. Epub 2008 Oct 29.PMID: 18971352 [PubMed - indexed for MEDLINE]Related articles

AMP kinase: heart, cancer and the CNS--view from the chair.

Deshaies Y.

Int J Obes (Lond). 2008 Sep;32 Suppl 4:S24-8. No abstract available. PMID: 18719594 [PubMed - indexed for MEDLINE]Related articles

Comprehensive genetic analysis of the dipeptidyl peptidase-4 gene and cardiovascular disease risk factors in obese individuals.

Bouchard L, Faucher G, Tchernof A, Deshaies Y, Lebel S, Hould FS, Marceau P, Vohl MC.

Acta Diabetol. 2009 Mar;46(1):13-21. Epub 2008 Aug 6.PMID: 18682883 [PubMed - indexed for MEDLINE]Related articles

Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism.

Dallaire P, Bellmann K, Laplante M, Gélinas S, Centeno-Baez C, Penfornis P, Peyot ML, Latour MG, Lamontagne J, Trujillo ME, Scherer PE, Prentki M, Deshaies Y, Marette A.

Diabetes. 2008 Aug;57(8):1999-2011. Epub 2008 May 5.PMID: 18458147 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor-gamma-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status.

Festuccia WT, Oztezcan S, Laplante M, Berthiaume M, Michel C, Dohgu S, Denis RG, Brito MN, Brito NA, Miller DS, Banks WA, Bartness TJ, Richard D, Deshaies Y.

Endocrinology. 2008 May;149(5):2121-30. Epub 2008 Jan 24.PMID: 18218698 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effect of fenofibrate and atorvastatin on in vivo kinetics of apolipoproteins B-100 and B-48 in subjects with type 2 diabetes mellitus with marked hypertriglyceridemia.

Hogue JC, Lamarche B, Deshaies Y, Tremblay AJ, Bergeron J, Gagné C, Couture P.

Metabolism. 2008 Feb;57(2):246-54.PMID: 18191056 [PubMed - indexed for MEDLINE]Related articles

Acylation-stimulating protein deficiency and altered adipose tissue in alternative complement pathway knockout mice.

Paglialunga S, Fisette A, Yan Y, Deshaies Y, Brouillette JF, Pekna M, Cianflone K.

Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E521-9. Epub 2007 Dec 26.PMID: 18160458 [PubMed - indexed for MEDLINE]Related articlesFree article

Visceral adipose tissue zinc finger protein 36 mRNA levels are correlated with insulin, insulin resistance index, and adiponectinemia in women.

Bouchard L, Vohl MC, Deshaies Y, Rhéaume C, Daris M, Tchernof A.

Eur J Endocrinol. 2007 Oct;157(4):451-7.PMID: 17893259 [PubMed - indexed for MEDLINE]Related articlesFree article

CYR61 polymorphisms are associated with plasma HDL-cholesterol levels in obese individuals.

Bouchard L, Tchernof A, Deshaies Y, Lebel S, Hould FS, Marceau P, Vohl MC.

Clin Genet. 2007 Sep;72(3):224-9.PMID: 17718860 [PubMed - indexed for MEDLINE]Related articles

Obesity-associated improvements in metabolic profile through expansion of adipose tissue.

Kim JY, van de Wall E, Laplante M, Azzara A, Trujillo ME, Hofmann SM, Schraw T, Durand JL, Li H, Li G, Jelicks LA, Mehler MF, Hui DY, Deshaies Y, Shulman GI, Schwartz GJ, Scherer PE.

J Clin Invest. 2007 Sep;117(9):2621-37.PMID: 17717599 [PubMed - indexed for MEDLINE]Related articlesFree article

Acylation-stimulating protein/C5L2-neutralizing antibodies alter triglyceride metabolism in vitro and in vivo.

Cui W, Paglialunga S, Kalant D, Lu H, Roy C, Laplante M, Deshaies Y, Cianflone K.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1482-91. Epub 2007 Aug 21.PMID: 17711993 [PubMed - indexed for MEDLINE]Related articlesFree article

11beta-HSD1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids toward oxidative tissues.

Berthiaume M, Laplante M, Festuccia WT, Cianflone K, Turcotte LP, Joanisse DR, Olivecrona G, Thieringer R, Deshaies Y.

Am J Physiol Endocrinol Metab. 2007 Oct;293(4):E1045-52. Epub 2007 Jul 31.PMID: 17666487 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced adipose tissue triglyceride synthesis and increased muscle fatty acid oxidation in C5L2 knockout mice.

Paglialunga S, Schrauwen P, Roy C, Moonen-Kornips E, Lu H, Hesselink MK, Deshaies Y, Richard D, Cianflone K.

J Endocrinol. 2007 Aug;194(2):293-304.PMID: 17641279 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic action of peroxisome proliferator-activated receptor gamma agonism in rats with exogenous hypercorticosteronemia.

Berthiaume M, Laplante M, Tchernof A, Deshaies Y.

Int J Obes (Lond). 2007 Nov;31(11):1660-70. Epub 2007 Jun 19.PMID: 17579631 [PubMed - indexed for MEDLINE]Related articles

ZFP36: a promising candidate gene for obesity-related metabolic complications identified by converging genomics.

Bouchard L, Tchernof A, Deshaies Y, Marceau S, Lescelleur O, Biron S, Vohl MC.

Obes Surg. 2007 Mar;17(3):372-82.PMID: 17546847 [PubMed - indexed for MEDLINE]Related articles

Kinetics of plasma apolipoprotein C-III as a determinant of diet-induced changes in plasma triglyceride levels.

Desroches S, Ruel IL, Deshaies Y, Paradis ME, Archer WR, Couture P, Bergeron N, Lamarche B.

Eur J Clin Nutr. 2008 Jan;62(1):10-7. Epub 2007 Feb 14.PMID: 17299465 [PubMed - indexed for MEDLINE]Related articles

Depot-specific modulation of rat intraabdominal adipose tissue lipid metabolism by pharmacological inhibition of 11beta-hydroxysteroid dehydrogenase type 1.

Berthiaume M, Laplante M, Festuccia W, Gélinas Y, Poulin S, Lalonde J, Joanisse DR, Thieringer R, Deshaies Y.

Endocrinology. 2007 May;148(5):2391-7. Epub 2007 Feb 1.PMID: 17272400 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of adipose tissues in the early hypolipidemic action of PPARgamma agonism in the rat.

Laplante M, Festuccia WT, Soucy G, Gélinas Y, Lalonde J, Deshaies Y.

Am J Physiol Regul Integr Comp Physiol. 2007 Apr;292(4):R1408-17. Epub 2006 Dec 14.PMID: 17170230 [PubMed - indexed for MEDLINE]Related articles

Effects of rimonabant (SR141716) on fasting-induced hypothalamic-pituitary-adrenal axis and neuronal activation in lean and obese Zucker rats.

Doyon C, Denis RG, Baraboi ED, Samson P, Lalonde J, Deshaies Y, Richard D.

Diabetes. 2006 Dec;55(12):3403-10.PMID: 17130486 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of the depot specificity of peroxisome proliferator-activated receptor gamma action on adipose tissue metabolism.

Laplante M, Festuccia WT, Soucy G, Gélinas Y, Lalonde J, Berger JP, Deshaies Y.

Diabetes. 2006 Oct;55(10):2771-8.PMID: 17003342 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial lipase is associated with inflammation in humans.

Paradis ME, Badellino KO, Rader DJ, Deshaies Y, Couture P, Archer WR, Bergeron N, Lamarche B.

J Lipid Res. 2006 Dec;47(12):2808-13. Epub 2006 Sep 15.PMID: 16980590 [PubMed - indexed for MEDLINE]Related articlesFree article

PPARgamma agonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control.

Festuccia WT, Laplante M, Berthiaume M, Gélinas Y, Deshaies Y.

Diabetologia. 2006 Oct;49(10):2427-36. Epub 2006 Aug 14.PMID: 16906479 [PubMed - indexed for MEDLINE]Related articles

Visceral adiposity and endothelial lipase.

Paradis ME, Badellino KO, Rader DJ, Tchernof A, Richard C, Luu-The V, Deshaies Y, Bergeron J, Archer WR, Couture P, Bergeron N, Lamarche B.

J Clin Endocrinol Metab. 2006 Sep;91(9):3538-43. Epub 2006 Jun 13.PMID: 16772345 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypocholesterolemic action of the selective estrogen receptor modulator acolbifene in intact and ovariectomized rats with diet-induced hypercholesterolemia.

Lemieux C, Gélinas Y, Lalonde J, Labrie F, Richard D, Deshaies Y.

Metabolism. 2006 May;55(5):605-13.PMID: 16631436 [PubMed - indexed for MEDLINE]Related articles

Leptin biosynthetic pathway in white adipocytes.

Cammisotto PG, Bukowiecki LJ, Deshaies Y, Bendayan M.

Biochem Cell Biol. 2006 Apr;84(2):207-14.PMID: 16609702 [PubMed - indexed for MEDLINE]Related articles

A high fat/high carbohydrate diet induces aortic valve disease in C57BL/6J mice.

Drolet MC, Roussel E, Deshaies Y, Couet J, Arsenault M.

J Am Coll Cardiol. 2006 Feb 21;47(4):850-5. Epub 2006 Jan 26.PMID: 16487855 [PubMed - indexed for MEDLINE]Related articles

Effects of fenofibrate on apolipoprotein kinetics in patients with coexisting dysbetalipoproteinemia and heterozygous familial hypercholesterolemia.

Tremblay AJ, Lamarche B, Ruel IL, Hogue JC, Deshaies Y, Gagné C, Couture P.

Atherosclerosis. 2006 Sep;188(1):203-12. Epub 2005 Dec 6.PMID: 16337207 [PubMed - indexed for MEDLINE]Related articles

The selective estrogen receptor modulator acolbifene reduces cholesterolemia independently of its anorectic action in control and cholesterol-fed rats.

Lemieux C, Gélinas Y, Lalonde J, Labrie F, Richard D, Deshaies Y.

J Nutr. 2005 Sep;135(9):2225-9.PMID: 16140902 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogen receptor alpha-mediated adiposity-lowering and hypocholesterolemic actions of the selective estrogen receptor modulator acolbifene.

Lemieux C, Phaneuf D, Labrie F, Giguère V, Richard D, Deshaies Y.

Int J Obes (Lond). 2005 Oct;29(10):1236-44.PMID: 15925950 [PubMed - indexed for MEDLINE]Related articles

Hypolipidemic action of the SERM acolbifene is associated with decreased liver MTP and increased SR-BI and LDL receptors.

Lemieux C, Gélinas Y, Lalonde J, Labrie F, Cianflone K, Deshaies Y.

J Lipid Res. 2005 Jun;46(6):1285-94. Epub 2005 Mar 1.PMID: 15741653 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of leptin secretion from white adipocytes by insulin, glycolytic substrates, and amino acids.

Cammisotto PG, Gélinas Y, Deshaies Y, Bukowiecki LJ.

Am J Physiol Endocrinol Metab. 2005 Jul;289(1):E166-71. Epub 2005 Mar 1.PMID: 15741239 [PubMed - indexed for MEDLINE]Related articlesFree article

PPARgamma and novel nuclear factors in the interplay between adipose tissue and the cardiovascular system: view from the chair.

Picard F, Deshaies Y.

Int J Obes (Lond). 2005 Mar;29 Suppl 1:S24-5. No abstract available. PMID: 15711578 [PubMed - indexed for MEDLINE]Related articles

The brown adipocyte: update on its metabolic role.

Sell H, Deshaies Y, Richard D.

Int J Biochem Cell Biol. 2004 Nov;36(11):2098-104. Review.PMID: 15313455 [PubMed - indexed for MEDLINE]Related articles

Correlating the degree of needle trauma during prostate brachytherapy and the development of acute urinary toxicity.

Eapen L, Kayser C, Deshaies Y, Perry G, E C, Morash C, Cygler JE, Wilkins D, Dahrouge S.

Int J Radiat Oncol Biol Phys. 2004 Aug 1;59(5):1392-4.PMID: 15275724 [PubMed - indexed for MEDLINE]Related articles

Actions of PPARgamma agonism on adipose tissue remodeling, insulin sensitivity, and lipemia in absence of glucocorticoids.

Berthiaume M, Sell H, Lalonde J, Gélinas Y, Tchernof A, Richard D, Deshaies Y.

Am J Physiol Regul Integr Comp Physiol. 2004 Nov;287(5):R1116-23. Epub 2004 Jul 15.PMID: 15256367 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor gamma agonism increases the capacity for sympathetically mediated thermogenesis in lean and ob/ob mice.

Sell H, Berger JP, Samson P, Castriota G, Lalonde J, Deshaies Y, Richard D.

Endocrinology. 2004 Aug;145(8):3925-34. Epub 2004 May 6.PMID: 15131020 [PubMed - indexed for MEDLINE]Related articlesFree article

Additive effects of leptin and topiramate in reducing fat deposition in lean and obese ob/ob mice.

Lalonde J, Samson P, Poulin S, Deshaies Y, Richard D.

Physiol Behav. 2004 Jan;80(4):415-20.PMID: 14741225 [PubMed - indexed for MEDLINE]Related articles

A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity.

Combs TP, Pajvani UB, Berg AH, Lin Y, Jelicks LA, Laplante M, Nawrocki AR, Rajala MW, Parlow AF, Cheeseboro L, Ding YY, Russell RG, Lindemann D, Hartley A, Baker GR, Obici S, Deshaies Y, Ludgate M, Rossetti L, Scherer PE.

Endocrinology. 2004 Jan;145(1):367-83. Epub 2003 Oct 23.PMID: 14576179 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of a novel mutation causing hepatic lipase deficiency among French Canadians.

Ruel IL, Couture P, Gagne C, Deshaies Y, Simard J, Hegele RA, Lamarche B.

J Lipid Res. 2003 Aug;44(8):1508-14. Epub 2003 Jun 1.PMID: 12777476 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of leptin secretion from white adipocytes by free fatty acids.

Cammisotto PG, Gélinas Y, Deshaies Y, Bukowiecki LJ.

Am J Physiol Endocrinol Metab. 2003 Sep;285(3):E521-6. Epub 2003 May 7.PMID: 12736159 [PubMed - indexed for MEDLINE]Related articlesFree article

Cod protein lowers the hepatic triglyceride secretion rate in rats.

Demonty I, Deshaies Y, Lamarche B, Jacques H.

J Nutr. 2003 May;133(5):1398-402.PMID: 12730428 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic effects of dehydroepiandrosterone on rat adipose tissue metabolism.

Mauriège P, Martel C, Langin D, Lacaille M, Després JP, Bélanger A, Labrie F, Deshaies Y.

Metabolism. 2003 Mar;52(3):264-72.PMID: 12647261 [PubMed - indexed for MEDLINE]Related articles

The estrogen antagonist EM-652 and dehydroepiandrosterone prevent diet- and ovariectomy-induced obesity.

Lemieux C, Picard F, Labrie F, Richard D, Deshaies Y.

Obes Res. 2003 Mar;11(3):477-90.PMID: 12634448 [PubMed - indexed for MEDLINE]Related articles

Role of soy isoflavones in the hypotriglyceridemic effect of soy protein in the rat.

Demonty I, Lamarche B, Deshaies Y, Jacques H.

J Nutr Biochem. 2002 Nov;13(11):671-677.PMID: 12550064 [PubMed - as supplied by publisher]Related articles