PubMed

Polymorphisms of myo-inositol oxygenase gene are associated with Type 1 diabetes mellitus.

Yang B, Hodgkinson A, Millward BA, Demaine AG.

J Diabetes Complications. 2009 Nov 5. [Epub ahead of print]PMID: 19896870 [PubMed - as supplied by publisher]Related articles

Genetic association analyses of non-synonymous single nucleotide polymorphisms in diabetic nephropathy.

Savage DA, Patterson CC, Deloukas P, Whittaker P, McKnight AJ, Morrison J, Boulton AJ, Demaine AG, Marshall SM, Millward BA, Thomas SM, Viberti GC, Walker JD, Sadlier D, Maxwell AP, Bain SC.

Diabetologia. 2008 Nov;51(11):1998-2002. Epub 2008 Sep 5.PMID: 18773191 [PubMed - indexed for MEDLINE]Related articlesFree article

The SPINK1 N34S variant is associated with acute pancreatitis.

O'Reilly DA, Witt H, Rahman SH, Schulz HU, Sargen K, Kage A, Cartmell MT, Landt O, Larvin M, Demaine AG, McMahon MJ, Becker M, Kingsnorth AN.

Eur J Gastroenterol Hepatol. 2008 Aug;20(8):726-31.PMID: 18617776 [PubMed - indexed for MEDLINE]Related articles

Interleukin 12B gene polymorphism and apparent resistance to hepatitis C virus infection.

Hegazy D, Thurairajah P, Metzner M, Houldsworth A, Shaw S, Kaminski E, Demaine AG, Cramp ME.

Clin Exp Immunol. 2008 Jun;152(3):538-41. Epub 2008 Apr 16.PMID: 18422730 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial nitric oxide synthase polymorphisms are associated with hypertension and cardiovascular disease in renal transplantation.

Bhandary UV, Tse W, Yang B, Knowles MR, Demaine AG.

Nephrology (Carlton). 2008 Jun;13(4):348-55. Epub 2008 Mar 5. Erratum in: Nephrology (Carlton). 2008 Oct;13(7):659. Bhandary, Uswanathan V [corrected to Bhandary, Umanath Vasanth]. PMID: 18331440 [PubMed - indexed for MEDLINE]Related articles

High glucose induction of DNA-binding activity of the transcription factor NFkappaB in patients with diabetic nephropathy.

Yang B, Hodgkinson A, Oates PJ, Millward BA, Demaine AG.

Biochim Biophys Acta. 2008 May;1782(5):295-302. Epub 2008 Feb 15.PMID: 18325349 [PubMed - indexed for MEDLINE]Related articles

Keratin 8 sequence variants in patients with pancreatitis and pancreatic cancer.

Treiber M, Schulz HU, Landt O, Drenth JP, Castellani C, Real FX, Akar N, Ammann RW, Bargetzi M, Bhatia E, Demaine AG, Battagia C, Kingsnorth A, O'Reilly D, Truninger K, Koudova M, Spicak J, Cerny M, Menzel HJ, Moral P, Pignatti PF, Romanelli MG, Rickards O, De Stefano GF, Zarnescu NO, Choudhuri G, Sikora SS, Jansen JB, Weiss FU, Pietschmann M, Teich N, Gress TM, Ockenga J, Schmidt H, Kage A, Halangk J, Rosendahl J, Groneberg DA, Nickel R, Witt H.

J Mol Med. 2006 Dec;84(12):1015-22. Epub 2006 Oct 13.PMID: 17039343 [PubMed - indexed for MEDLINE]Related articles

Elevated activity of transcription factor nuclear factor of activated T-cells 5 (NFAT5) and diabetic nephropathy.

Yang B, Hodgkinson AD, Oates PJ, Kwon HM, Millward BA, Demaine AG.

Diabetes. 2006 May;55(5):1450-5.PMID: 16644704 [PubMed - indexed for MEDLINE]Related articlesFree article

Heat shock factor-1 and nuclear factor-kappaB are systemically activated in human acute pancreatitis.

O'Reilly DA, Roberts JR, Cartmell MT, Demaine AG, Kingsnorth AN.

JOP. 2006 Mar 9;7(2):174-84.PMID: 16525201 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytochrome P450 2E1 high activity polymorphism in alcohol abuse and end-organ disease.

Cartmell MT, Schulz HU, O'Reilly DA, Yang BM, Kielstein V, Dunlop SP, Halangk W, Demaine AG, Kingsnorth AN.

World J Gastroenterol. 2005 Nov 7;11(41):6445-9.PMID: 16425414 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose transporter polymorphisms are associated with clear-cell renal carcinoma.

Page T, Hodgkinson AD, Ollerenshaw M, Hammonds JC, Demaine AG.

Cancer Genet Cytogenet. 2005 Dec;163(2):151-5.PMID: 16337858 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in the IL-12B gene and outcome of HCV infection.

Houldsworth A, Metzner M, Rossol S, Shaw S, Kaminski E, Demaine AG, Cramp ME.

J Interferon Cytokine Res. 2005 May;25(5):271-6.PMID: 15871664 [PubMed - indexed for MEDLINE]Related articles

A novel polymorphism in the 5' flanking region of the glucose transporter (GLUT1) gene is strongly associated with diabetic nephropathy in patients with Type 1 diabetes mellitus.

Hodgkinson AD, Page T, Millward BA, Demaine AG.

J Diabetes Complications. 2005 Mar-Apr;19(2):65-9.PMID: 15745834 [PubMed - indexed for MEDLINE]Related articles

Association of the p22phox component of NAD(P)H oxidase with susceptibility to diabetic nephropathy in patients with type 1 diabetes.

Hodgkinson AD, Millward BA, Demaine AG.

Diabetes Care. 2003 Nov;26(11):3111-5.PMID: 14578247 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms of the aldose reductase gene and susceptibility to diabetic microvascular complications.

Demaine AG.

Curr Med Chem. 2003 Aug;10(15):1389-98. Review.PMID: 12871136 [PubMed - indexed for MEDLINE]Related articles

The response of antioxidant genes to hyperglycemia is abnormal in patients with type 1 diabetes and diabetic nephropathy.

Hodgkinson AD, Bartlett T, Oates PJ, Millward BA, Demaine AG.

Diabetes. 2003 Mar;52(3):846-51.PMID: 12606529 [PubMed - indexed for MEDLINE]Related articlesFree article

Continued rising trend of childhood Type 1 diabetes mellitus in Devon and Cornwall, England.

Zhao HX, Stenhouse E, Sanderson E, Soper C, Hughes P, Cross D, Demaine AG, Millward BA.

Diabet Med. 2003 Feb;20(2):168-70. No abstract available. PMID: 12581273 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms of the vascular endothelial growth factor and susceptibility to diabetic microvascular complications in patients with type 1 diabetes mellitus.

Yang B, Cross DF, Ollerenshaw M, Millward BA, Demaine AG.

J Diabetes Complications. 2003 Jan-Feb;17(1):1-6.PMID: 12505748 [PubMed - indexed for MEDLINE]Related articles

-to: Pinizzotto M, Castillo E, Fiaux M, Temier E, Gaillard RC, Ruiz J (2001) Paraoxanase 2 polymorphisms are associated with diabetic nephropathy in Type II diabetes. Diabetologia 44: 104-107.

Hodgkinson AD, Millward BA, Demaine AG.

Diabetologia. 2002 Jun;45(6):933-5. No abstract available. PMID: 12154776 [PubMed - indexed for MEDLINE]Related articles

Activation of NF-kappaB and MAP kinase cascades by hypothermic stress in endothelial cells.

Roberts JR, Rowe PA, Demaine AG.

Cryobiology. 2002 Apr;44(2):161-9.PMID: 12151271 [PubMed - indexed for MEDLINE]Related articles

Space-time clustering of childhood Type 1 diabetes in Devon and Cornwall, England.

Zhao HX, Moyeed RA, Stenhouse EA, Demaine AG, Millward BA.

Diabet Med. 2002 Aug;19(8):667-72.PMID: 12147148 [PubMed - indexed for MEDLINE]Related articles

Expression of hypoxia-inducible factor 1alpha in tumours of patients with glioblastoma.

Søndergaard KL, Hilton DA, Penney M, Ollerenshaw M, Demaine AG.

Neuropathol Appl Neurobiol. 2002 Jun;28(3):210-7.PMID: 12060345 [PubMed - indexed for MEDLINE]Related articles

Cytokine gene polymorphisms in acute pancreatitis.

Sargen K, Demaine AG, Kingsnorth AN.

JOP. 2000 Jul;1(2):24-35.PMID: 11852287 [PubMed - indexed for MEDLINE]Related articlesFree article

NFkappaB polymorphisms and susceptibility to type 1 diabetes.

Hegazy DM, O'Reilly DA, Yang BM, Hodgkinson AD, Millward BA, Demaine AG.

Genes Immun. 2001 Oct;2(6):304-8.PMID: 11607785 [PubMed - indexed for MEDLINE]Related articlesFree article

Drinking water composition and childhood-onset Type 1 diabetes mellitus in Devon and Cornwall, England.

Zhao HX, Mold MD, Stenhouse EA, Bird SC, Wright DE, Demaine AG, Millward BA.

Diabet Med. 2001 Sep;18(9):709-17.PMID: 11606168 [PubMed - indexed for MEDLINE]Related articles

Mutations of the cationic trypsinogen gene in hereditary and non-hereditary pancreatitis.

O'Reilly DA, Yang BM, Creighton JE, Demaine AG, Kingsnorth AN.

Digestion. 2001;64(1):54-60.PMID: 11549837 [PubMed - indexed for MEDLINE]Related articles

Aldose reductase expression is induced by hyperglycemia in diabetic nephropathy.

Hodgkinson AD, Søndergaard KL, Yang B, Cross DF, Millward BA, Demaine AG.

Kidney Int. 2001 Jul;60(1):211-8.PMID: 11422753 [PubMed - indexed for MEDLINE]Related articlesFree article

Study of polymorphisms in the CYP2E1 gene in patients with alcoholic pancreatitis.

Yang B, O'Reilly DA, Demaine AG, Kingsnorth AN.

Alcohol. 2001 Feb;23(2):91-7.PMID: 11331106 [PubMed - indexed for MEDLINE]Related articles

A study of cytokine gene polymorphisms and protein secretion in renal transplantation.

Cartwright NH, Keen LJ, Demaine AG, Hurlock NJ, McGonigle RJ, Rowe PA, Shaw JF, Szydlo RM, Kaminski ER.

Transpl Immunol. 2001 Feb;8(4):237-44.PMID: 11316066 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms of the glucose transporter (GLUT1) gene are associated with diabetic nephropathy.

Hodgkinson AD, Millward BA, Demaine AG.

Kidney Int. 2001 Mar;59(3):985-9.PMID: 11231353 [PubMed - indexed for MEDLINE]Related articlesFree article

The average age at onset is decreasing in children with Type 1 diabetes in Devon and Cornwall, England.

Zhao HX, Stenhouse E, Demaine AG, Millward BA.

Diabet Med. 2000 Dec;17(12):877. No abstract available. PMID: 11168332 [PubMed - indexed for MEDLINE]Related articles

A polymorphism in the promoter region of the gene for interleukin-6 is associated with susceptibility to type 1 diabetes mellitus.

Jahromi MM, Millward BA, Demaine AG.

J Interferon Cytokine Res. 2000 Oct;20(10):885-8.PMID: 11054276 [PubMed - indexed for MEDLINE]Related articles

Cytokine secretion in mixed lymphocyte culture: a prognostic indicator of renal allograft rejection in addition to HLA mismatching.

Cartwright NH, Demaine AG, Hurlock NJ, McGonigle RJ, Rowe PA, Shaw JF, Szydlo RM, Kaminski ER.

Transpl Immunol. 2000 Jun;8(2):109-14.PMID: 11005316 [PubMed - indexed for MEDLINE]Related articles

Chemokines MCP-1 and RANTES in isolated rat pancreatic acinar cells treated with CCK and ethanol in vitro.

Yang BM, Demaine AG, Kingsnorth A.

Pancreas. 2000 Jul;21(1):22-31.PMID: 10881929 [PubMed - indexed for MEDLINE]Related articles

Investigation of the interleukin 1 gene cluster and its association with acute pancreatitis.

Smithies AM, Sargen K, Demaine AG, Kingsnorth AN.

Pancreas. 2000 Apr;20(3):234-40.PMID: 10766448 [PubMed - indexed for MEDLINE]Related articles

Association of tumour necrosis factor microsatellite haplotypes with chronic pancreatitis

O'Reilly DA, Sargen KD, Dunlop S, Demaine AG, Kingsnorth AN.

Br J Surg. 2000 Mar;87(3):362-73.PMID: 10718810 [PubMed - as supplied by publisher]Related articles

Seasonality of birth in children with diabetes. Results of various studies differ.

Zhao H, Demaine AG, Millward BA.

BMJ. 2000 Mar 11;320(7236):716. No abstract available. PMID: 10710597 [PubMed - indexed for MEDLINE]Related articlesFree article

The HLA-E locus is associated with age at onset and susceptibility to type 1 diabetes mellitus.

Hodgkinson AD, Millward BA, Demaine AG.

Hum Immunol. 2000 Mar;61(3):290-5.PMID: 10689118 [PubMed - indexed for MEDLINE]Related articles

Incidence of childhood-onset Type 1 diabetes mellitus in Devon and Cornwall, England, 1975-1996.

Zhao HX, Stenhouse E, Soper C, Hughes P, Sanderson E, Baumer JH, Demaine AG, Millward BA.

Diabet Med. 1999 Dec;16(12):1030-5.PMID: 10656232 [PubMed - indexed for MEDLINE]Related articles

Susceptibility to diabetic neuropathy in patients with insulin dependent diabetes mellitus is associated with a polymorphism at the 5' end of the aldose reductase gene.

Heesom AE, Millward A, Demaine AG.

J Neurol Neurosurg Psychiatry. 1998 Feb;64(2):213-6.PMID: 9489533 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphism in the 5'-end of the aldose reductase gene is strongly associated with the development of diabetic nephropathy in type I diabetes.

Heesom AE, Hibberd ML, Millward A, Demaine AG.

Diabetes. 1997 Feb;46(2):287-91.PMID: 9000706 [PubMed - indexed for MEDLINE]Related articles

The angiotensin I-converting enzyme (ACE) locus is strongly associated with age and duration of diabetes in patients with type I diabetes.

Hibberd ML, Millward BA, Demaine AG.

J Diabetes Complications. 1997 Jan-Feb;11(1):2-8.PMID: 9025006 [PubMed - indexed for MEDLINE]Related articles

Chromosome 7q35 and susceptibility to diabetic microvascular complications.

Patel A, Hibberd ML, Millward BA, Demaine AG.

J Diabetes Complications. 1996 Mar-Apr;10(2):62-7.PMID: 8777332 [PubMed - indexed for MEDLINE]Related articles

Cloning, structure and mRNA expression of human Cctg, which encodes the chaperonin subunit CCT gamma.

Walkley NA, Demaine AG, Malik AN.

Biochem J. 1996 Jan 15;313 ( Pt 2):381-9.PMID: 8573069 [PubMed - indexed for MEDLINE]Related articlesFree article

A new marker in the HLA class I region is associated with the age at onset of IDDM.

Demaine AG, Hibberd ML, Mangles D, Millward BA.

Diabetologia. 1995 May;38(5):623-8.PMID: 7489848 [PubMed - indexed for MEDLINE]Related articles

Susceptibility to autoimmune thyroiditis in Down's syndrome is associated with the major histocompatibility class II DQA 0301 allele.

Nicholson LB, Wong FS, Ewins DL, Butler J, Holland A, Demaine AG, McGregor AM.

Clin Endocrinol (Oxf). 1994 Sep;41(3):381-3.PMID: 7955446 [PubMed - indexed for MEDLINE]Related articles

An investigation of the role of atrial natriuretic factor in the development of diabetic nephropathy.

Morris CA, Page RA, Demaine AG, Williams JD, Malik AN.

Biochem Soc Trans. 1994 Aug;22(3):355S. No abstract available. PMID: 7821608 [PubMed - indexed for MEDLINE]Related articles

T-cell receptor constant beta germline gene polymorphisms and susceptibility to autoimmune hepatitis.

Manabe K, Hibberd ML, Donaldson PT, Underhill JA, Doherty DG, Demaine AG, Mieli-Vergani G, Eddleston AL, Williams R.

Gastroenterology. 1994 May;106(5):1321-5.PMID: 7909781 [PubMed - indexed for MEDLINE]Related articles

HLA-DPB1 polymorphisms in patients with hyperthyroid Graves' disease and early onset myasthenia gravis.

Ratanachaiyavong S, Fleming D, Janer M, Demaine AG, Willcox N, Newsom-Davis J, McGregor AM.

Autoimmunity. 1994;17(2):99-104.PMID: 8061167 [PubMed - indexed for MEDLINE]Related articles

Polymorphism in the human complement C4 genes and genetic susceptibility to autoimmune hepatitis.

Doherty DG, Underhill JA, Donaldson PT, Manabe K, Mieli-Vergani G, Eddleston AL, Vergani D, Demaine AG, Williams R.

Autoimmunity. 1994;18(4):243-9.PMID: 7858109 [PubMed - indexed for MEDLINE]Related articles