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2002 1
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Interactions between herbal medicines and prescribed drugs: an updated systematic review.
Izzo AA, Ernst E. Izzo AA, et al. Drugs. 2009;69(13):1777-98. doi: 10.2165/11317010-000000000-00000. Drugs. 2009. PMID: 19719333 Review.
Clinical trials indicate that St John's wort (Hypericum perforatum), via cytochrome P450 (CYP) and/or P-glycoprotein induction, reduces the plasma concentrations (and/or increases the clearance) of alprazolam, amitriptyline, atorvastatin, chlorzoxazone, ciclosporin, debrisoqui …
Clinical trials indicate that St John's wort (Hypericum perforatum), via cytochrome P450 (CYP) and/or P-glycoprotein induction, reduces the …
Smoking and Parkinson's disease: explanatory hypothesis.
Allam MF, Serrano del Castillo A, Fernández-Crehuet Navajas R. Allam MF, et al. Int J Neurosci. 2002 Jul;112(7):851-4. doi: 10.1080/00207450290025860. Int J Neurosci. 2002. PMID: 12424825 Review.
Pooled odds ratio of these studies was 0.77 with 95% confidence interval 0.60 to 0.97. It was suggested that smoking induces debrisoquine 4-hydroxylase, which is responsible for the metabolism of antipsychotic drugs and the detoxification of certain environmental toxins kn …
Pooled odds ratio of these studies was 0.77 with 95% confidence interval 0.60 to 0.97. It was suggested that smoking induces debrisoquine …