PubMed

Regulation of the benzamil-insensitive salt taste receptor by intracellular Ca2+, protein kinase C, and calcineurin.

Lyall V, Phan TH, Mummalaneni S, Melone P, Mahavadi S, Murthy KS, DeSimone JA.

J Neurophysiol. 2009 Sep;102(3):1591-605. Epub 2009 Jun 24.PMID: 19553475 [PubMed - indexed for MEDLINE]Related articles

Nicotine activates TRPM5-dependent and independent taste pathways.

Oliveira-Maia AJ, Stapleton-Kotloski JR, Lyall V, Phan TH, Mummalaneni S, Melone P, Desimone JA, Nicolelis MA, Simon SA.

Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1596-601. Epub 2009 Jan 21.PMID: 19164511 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of Maillard reacted peptides on human salt taste and the amiloride-insensitive salt taste receptor (TRPV1t).

Katsumata T, Nakakuki H, Tokunaga C, Fujii N, Egi M, Phan TH, Mummalaneni S, DeSimone JA, Lyall V.

Chem Senses. 2008 Sep;33(7):665-80. Epub 2008 Jul 5.PMID: 18603652 [PubMed - indexed for MEDLINE]Related articlesFree article

Candidemia complicated by endophthalmitis: a prospective analysis.

Kannangara S, Shindler D, Kunimoto DY, Sell B, DeSimone JA.

Eur J Clin Microbiol Infect Dis. 2007 Nov;26(11):839-41. No abstract available. PMID: 17668252 [PubMed - indexed for MEDLINE]Related articles

Effect of nicotine on chorda tympani responses to salty and sour stimuli.

Lyall V, Phan TH, Mummalaneni S, Mansouri M, Heck GL, Kobal G, DeSimone JA.

J Neurophysiol. 2007 Sep;98(3):1662-74. Epub 2007 Jul 5.PMID: 17615133 [PubMed - indexed for MEDLINE]Related articlesFree article

A psychophysical and electrophysiological analysis of salt taste in Trpv1 null mice.

Treesukosol Y, Lyall V, Heck GL, DeSimone JA, Spector AC.

Am J Physiol Regul Integr Comp Physiol. 2007 May;292(5):R1799-809. Epub 2007 Jan 18.PMID: 17234959 [PubMed - indexed for MEDLINE]Related articles

Taste receptors in the gastrointestinal tract III. Salty and sour taste: sensing of sodium and protons by the tongue.

DeSimone JA, Lyall V.

Am J Physiol Gastrointest Liver Physiol. 2006 Dec;291(6):G1005-10. Epub 2006 Jun 29. Review.PMID: 16809639 [PubMed - indexed for MEDLINE]Related articlesFree article

Bloodstream infections in hospitalized adults with sickle cell disease: a retrospective analysis.

Chulamokha L, Scholand SJ, Riggio JM, Ballas SK, Horn D, DeSimone JA.

Am J Hematol. 2006 Oct;81(10):723-8.PMID: 16795063 [PubMed - indexed for MEDLINE]Related articles

Pneumococcal vaccination during pregnancy for preventing infant infection.

Chaithongwongwatthana S, Yamasmit W, Limpongsanurak S, Lumbiganon P, Desimone JA, Baxter J, Tolosa JE.

Cochrane Database Syst Rev. 2006 Jan 25;(1):CD004903. Review.PMID: 16437503 [PubMed - indexed for MEDLINE]Related articles

Intracellular pH modulates taste receptor cell volume and the phasic part of the chorda tympani response to acids.

Lyall V, Pasley H, Phan TH, Mummalaneni S, Heck GL, Vinnikova AK, DeSimone JA.

J Gen Physiol. 2006 Jan;127(1):15-34.PMID: 16380442 [PubMed - indexed for MEDLINE]Related articlesFree article

Anti-HIV-1 microbicides -- 'chemical condoms' designed to limit the scourge of the HIV-1 pandemic.

Scholand SJ, DeSimone JA, Pomerantz RJ.

Curr Pharm Des. 2005;11(29):3747-56. Review.PMID: 16305509 [PubMed - indexed for MEDLINE]Related articles

Attenuation of HIV-1 infection by other microbial agents.

Kannangara S, DeSimone JA, Pomerantz RJ.

J Infect Dis. 2005 Sep 15;192(6):1003-9. Epub 2005 Aug 12. Review.PMID: 16107952 [PubMed - indexed for MEDLINE]Related articles

Antiretroviral therapy in the developing world.

Chulamokha L, DeSimone JA, Pomerantz RJ.

J Neurovirol. 2005;11 Suppl 1:76-80. Review. No abstract available. PMID: 15960241 [PubMed - indexed for MEDLINE]Related articles

Ethanol modulates the VR-1 variant amiloride-insensitive salt taste receptor. II. Effect on chorda tympani salt responses.

Lyall V, Heck GL, Phan TH, Mummalaneni S, Malik SA, Vinnikova AK, Desimone JA.

J Gen Physiol. 2005 Jun;125(6):587-600.PMID: 15928404 [PubMed - indexed for MEDLINE]Related articlesFree article

Ethanol modulates the VR-1 variant amiloride-insensitive salt taste receptor. I. Effect on TRC volume and Na+ flux.

Lyall V, Heck GL, Phan TH, Mummalaneni S, Malik SA, Vinnikova AK, DeSimone JA.

J Gen Physiol. 2005 Jun;125(6):569-85.PMID: 15928403 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel vanilloid receptor-1 (VR-1) variant mammalian salt taste receptor.

Lyall V, Heck GL, Vinnikova AK, Ghosh S, Phan TH, Desimone JA.

Chem Senses. 2005 Jan;30 Suppl 1:i42-3. No abstract available. PMID: 15738186 [PubMed - indexed for MEDLINE]Related articlesFree article

Successful desensitization to enfuvirtide after a hypersensitivity reaction in an HIV-1-infected man.

DeSimone JA, Ojha A, Pathak R, Cohn J.

Clin Infect Dis. 2004 Nov 15;39(10):e110-2. Epub 2004 Oct 26.PMID: 15546072 [PubMed - indexed for MEDLINE]Related articles

The mammalian amiloride-insensitive non-specific salt taste receptor is a vanilloid receptor-1 variant.

Lyall V, Heck GL, Vinnikova AK, Ghosh S, Phan TH, Alam RI, Russell OF, Malik SA, Bigbee JW, DeSimone JA.

J Physiol. 2004 Jul 1;558(Pt 1):147-59. Epub 2004 May 14.PMID: 15146042 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of Mycobacterium avium complex immune reconstitution disease in HIV-1-infected individuals.

Desimone JA Jr, Babinchak TJ, Kaulback KR, Pomerantz RJ.

AIDS Patient Care STDS. 2003 Dec;17(12):617-22.PMID: 14746655 [PubMed - indexed for MEDLINE]Related articles

Basolateral Na+-H+ exchanger-1 in rat taste receptor cells is involved in neural adaptation to acidic stimuli.

Lyall V, Alam RI, Malik SA, Phan TH, Vinnikova AK, Heck GL, DeSimone JA.

J Physiol. 2004 Apr 1;556(Pt 1):159-73. Epub 2004 Jan 14. Erratum in: J Physiol. 2004 May 1;556(Pt 3):1013. PMID: 14724181 [PubMed - indexed for MEDLINE]Related articlesFree article

Na+-H+ exchange activity in taste receptor cells.

Vinnikova AK, Alam RI, Malik SA, Ereso GL, Feldman GM, McCarty JM, Knepper MA, Heck GL, DeSimone JA, Lyall V.

J Neurophysiol. 2004 Mar;91(3):1297-313. Epub 2003 Nov 5.PMID: 14602837 [PubMed - indexed for MEDLINE]Related articlesFree article

Infection of transjugular intrahepatic portosystemic shunt devices.

DeSimone JA Jr.

Clin Infect Dis. 2003 Sep 1;37(5):740-1. No abstract available. PMID: 12942415 [PubMed - indexed for MEDLINE]Related articles

Salt-evoked lingual surface potential in humans.

Feldman GM, Mogyorosi A, Heck GL, DeSimone JA, Santos CR, Clary RA, Lyall V.

J Neurophysiol. 2003 Sep;90(3):2060-4. Epub 2003 May 7.PMID: 12736236 [PubMed - indexed for MEDLINE]Related articlesFree article

Sensorineural hearing loss associated with intrathecal vancomycin.

Klibanov OM, Filicko JE, DeSimone JA Jr, Tice DS.

Ann Pharmacother. 2003 Jan;37(1):61-5.PMID: 12503934 [PubMed - indexed for MEDLINE]Related articles

Modulation of rat chorda tympani NaCl responses and intracellular Na+ activity in polarized taste receptor cells by pH.

Lyall V, Alam RI, Phan TH, Russell OF, Malik SA, Heck GL, DeSimone JA.

J Gen Physiol. 2002 Dec;120(6):793-815.PMID: 12451050 [PubMed - indexed for MEDLINE]Related articlesFree article

New methods for the detection of HIV.

DeSimone JA, Pomerantz RJ.

Clin Lab Med. 2002 Sep;22(3):573-92, v. Review.PMID: 12244587 [PubMed - indexed for MEDLINE]Related articles

Central nervous system infections in individuals with HIV-1 infection.

Mamidi A, DeSimone JA, Pomerantz RJ.

J Neurovirol. 2002 Jun;8(3):158-67. Review.PMID: 12053271 [PubMed - indexed for MEDLINE]Related articles

Tobacco use in HIV-infected women.

Steinberg MB, DeSimone JA, Abatemarco D.

Ann Intern Med. 2002 Jun 4;136(11):W1. No abstract available. PMID: 12044145 [PubMed - indexed for MEDLINE]Related articlesFree article

Excitation and adaptation in the detection of hydrogen ions by taste receptor cells: a role for cAMP and Ca(2+).

Lyall V, Alam RI, Phan TH, Phan DQ, Heck GL, DeSimone JA.

J Neurophysiol. 2002 Jan;87(1):399-408.PMID: 11784758 [PubMed - indexed for MEDLINE]Related articlesFree article

Acid detection by taste receptor cells.

DeSimone JA, Lyall V, Heck GL, Feldman GM.

Respir Physiol. 2001 Dec;129(1-2):231-45. Review.PMID: 11738657 [PubMed - indexed for MEDLINE]Related articles

A novel pharmacological probe links the amiloride-insensitive NaCl, KCl, and NH(4)Cl chorda tympani taste responses.

DeSimone JA, Lyall V, Heck GL, Phan TH, Alam RI, Feldman GM, Buch RM.

J Neurophysiol. 2001 Nov;86(5):2638-41.PMID: 11698552 [PubMed - indexed for MEDLINE]Related articlesFree article

Decrease in rat taste receptor cell intracellular pH is the proximate stimulus in sour taste transduction.

Lyall V, Alam RI, Phan DQ, Ereso GL, Phan TH, Malik SA, Montrose MH, Chu S, Heck GL, Feldman GM, DeSimone JA.

Am J Physiol Cell Physiol. 2001 Sep;281(3):C1005-13.PMID: 11502578 [PubMed - indexed for MEDLINE]Related articlesFree article

Inflammatory reactions in HIV-1-infected persons after initiation of highly active antiretroviral therapy.

DeSimone JA, Pomerantz RJ, Babinchak TJ.

Ann Intern Med. 2000 Sep 19;133(6):447-54. Review.PMID: 10975963 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of rat chorda tympani sodium responses: evidence for age-dependent changes in global amiloride-sensitive Na(+) channel kinetics.

Hendricks SJ, Stewart RE, Heck GL, DeSimone JA, Hill DL.

J Neurophysiol. 2000 Sep;84(3):1531-44.PMID: 10980025 [PubMed - indexed for MEDLINE]Related articlesFree article

Sustained bacteremia associated with transjugular intrahepatic portosystemic shunt (TIPS).

DeSimone JA, Beavis KG, Eschelman DJ, Henning KJ.

Clin Infect Dis. 2000 Feb;30(2):384-6.PMID: 10671346 [PubMed - indexed for MEDLINE]Related articles

Focus on "rapid entry of bitter and sweet tastants into liposomes and taste cells: implications for signal transduction".

DeSimone JA.

Am J Physiol Cell Physiol. 2000 Jan;278(1):C13-6. No abstract available. PMID: 10644506 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of osmolarity on taste receptor cell size and function.

Lyall V, Heck GL, DeSimone JA, Feldman GM.

Am J Physiol. 1999 Oct;277(4 Pt 1):C800-13.PMID: 10516110 [PubMed - indexed for MEDLINE]Related articlesFree article

Anion size of sodium salts and simple taste reaction times.

Delwiche JF, Halpern BP, Desimone JA.

Physiol Behav. 1999 Mar;66(1):27-32.PMID: 10222469 [PubMed - indexed for MEDLINE]Related articles

Acid-induced responses in hamster chorda tympani and intracellular pH tracking by taste receptor cells.

Stewart RE, Lyall V, Feldman GM, Heck GL, DeSimone JA.

Am J Physiol. 1998 Jul;275(1 Pt 1):C227-38.PMID: 9688854 [PubMed - indexed for MEDLINE]Related articlesFree article

Self-inhibition in Ca2+ -evoked taste responses: a novel tool for functional dissection of salt taste transduction mechanisms.

Kloub MA, Heck GL, DeSimone JA.

J Neurophysiol. 1998 Feb;79(2):911-21.PMID: 9463452 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of extracellular pH, PCO2, and HCO3- on intracellular pH in isolated rat taste buds.

Lyall V, Feldman GM, Heck GL, DeSimone JA.

Am J Physiol. 1997 Sep;273(3 Pt 1):C1008-19.PMID: 9316422 [PubMed - indexed for MEDLINE]Related articles

Chorda tympani responses under lingual voltage clamp: implications for NH4 salt taste transduction.

Kloub MA, Heck GL, DeSimone JA.

J Neurophysiol. 1997 Mar;77(3):1393-406.PMID: 9084605 [PubMed - indexed for MEDLINE]Related articlesFree article

New perspectives in a gustatory physiology: transduction, development, and plasticity.

Stewart RE, DeSimone JA, Hill DL.

Am J Physiol. 1997 Jan;272(1 Pt 1):C1-26. Review.PMID: 9038806 [PubMed - indexed for MEDLINE]Related articles

Taste-mixture suppression: functional dissection of cellular and paracellular origins.

Stewart RE, Heck GL, Desimone JA.

J Neurophysiol. 1996 May;75(5):2124-8.PMID: 8734608 [PubMed - indexed for MEDLINE]Related articles

Chorda tympani taste response of rat to hydrochloric acid subject to voltage-clamped lingual receptive field.

DeSimone JA, Callaham EM, Heck GL.

Am J Physiol. 1995 May;268(5 Pt 1):C1295-300.PMID: 7762623 [PubMed - indexed for MEDLINE]Related articles

Effects of voltage perturbation of the lingual receptive field on chorda tympani responses to Na+ and K+ salts in the rat: implications for gustatory transduction.

Ye Q, Heck GL, DeSimone JA.

J Gen Physiol. 1994 Nov;104(5):885-907.PMID: 7876827 [PubMed - indexed for MEDLINE]Related articlesFree article

Dietary Na(+)-restriction prevents development of functional Na+ channels in taste cell apical membranes: proof by in vivo membrane voltage perturbation.

Ye Q, Stewart RE, Heck GL, Hill DL, DeSimone JA.

J Neurophysiol. 1993 Oct;70(4):1713-6.PMID: 8283226 [PubMed - indexed for MEDLINE]Related articles

Voltage dependence of the rat chorda tympani response to Na+ salts: implications for the functional organization of taste receptor cells.

Ye Q, Heck GL, DeSimone JA.

J Neurophysiol. 1993 Jul;70(1):167-78.PMID: 8395573 [PubMed - indexed for MEDLINE]Related articles

Ion pathways in the taste bud and their significance for transduction.

DeSimone JA, Ye Q, Heck GL.

Ciba Found Symp. 1993;179:218-29; discussion 229-34. Review.PMID: 7513272 [PubMed - indexed for MEDLINE]Related articles

Dialysis disequilibrium syndrome (DDS) in the rat: role of the "reverse urea effect".

Silver SM, DeSimone JA Jr, Smith DA, Sterns RH.

Kidney Int. 1992 Jul;42(1):161-6.PMID: 1635345 [PubMed - indexed for MEDLINE]Related articles