PubMed

Autoimmune thyroiditis: a model uniquely suited to probe regulatory T cell function.

Kong YC, Morris GP, Brown NK, Yan Y, Flynn JC, David CS.

J Autoimmun. 2009 Nov-Dec;33(3-4):239-46. Epub 2009 Oct 12.PMID: 19822405 [PubMed - in process]Related articles

Spontaneous autoimmune myocarditis and cardiomyopathy in HLA-DQ8.NODAbo transgenic mice.

Taneja V, David CS.

J Autoimmun. 2009 Nov-Dec;33(3-4):260-9. Epub 2009 Oct 7.PMID: 19811893 [PubMed - in process]Related articles

Transgenic expression of the 3D polymerase inhibits Theiler's virus infection and demyelination.

Kerkvliet J, Zoecklein L, Papke L, Denic A, Bieber AJ, Pease LR, David CS, Rodriguez M.

J Virol. 2009 Dec;83(23):12279-89. Epub 2009 Sep 16.PMID: 19759133 [PubMed - in process]Related articles

HLA-DQB1*0602 determines disease susceptibility in a new "humanized" multiple sclerosis model in HLA-DR15 (DRB1*1501;DQB1*0602) transgenic mice.

Kaushansky N, Altmann DM, Ascough S, David CS, Lassmann H, Ben-Nun A.

J Immunol. 2009 Sep 1;183(5):3531-41. Epub 2009 Jul 31.PMID: 19648275 [PubMed - indexed for MEDLINE]Related articles

Induction of antigen-specific tolerance by oral administration of Lactococcus lactis delivered immunodominant DQ8-restricted gliadin peptide in sensitized nonobese diabetic Abo Dq8 transgenic mice.

Huibregtse IL, Marietta EV, Rashtak S, Koning F, Rottiers P, David CS, van Deventer SJ, Murray JA.

J Immunol. 2009 Aug 15;183(4):2390-6. Epub 2009 Jul 27.PMID: 19635921 [PubMed - indexed for MEDLINE]Related articles

Early gene expression changes induced by the bacterial superantigen staphylococcal enterotoxin B and its modulation by a proteasome inhibitor.

Rajagopalan G, Tilahun AY, Asmann YW, David CS.

Physiol Genomics. 2009 May 13;37(3):279-93. Epub 2009 Mar 31.PMID: 19336531 [PubMed - indexed for MEDLINE]Related articles

The role of HLA-DQ8 beta57 polymorphism in the anti-gluten T-cell response in coeliac disease.

Hovhannisyan Z, Weiss A, Martin A, Wiesner M, Tollefsen S, Yoshida K, Ciszewski C, Curran SA, Murray JA, David CS, Sollid LM, Koning F, Teyton L, Jabri B.

Nature. 2008 Nov 27;456(7221):534-8.PMID: 19037317 [PubMed - indexed for MEDLINE]Related articles

Polymeric binders suppress gliadin-induced toxicity in the intestinal epithelium.

Pinier M, Verdu EF, Nasser-Eddine M, David CS, Vézina A, Rivard N, Leroux JC.

Gastroenterology. 2009 Jan;136(1):288-98. Epub 2008 Sep 20.PMID: 18992747 [PubMed - indexed for MEDLINE]Related articles

Identification of CD4 T-cell epitopes in soluble liver antigen/liver pancreas autoantigen in autoimmune hepatitis.

Mix H, Weiler-Normann C, Thimme R, Ahlenstiel G, Shin EC, Herkel J, David CS, Lohse AW, Rehermann B.

Gastroenterology. 2008 Dec;135(6):2107-18. Epub 2008 Jul 31.PMID: 18773898 [PubMed - indexed for MEDLINE]Related articlesFree article

Delineating the role of the HLA-DR4 "shared epitope" in susceptibility versus resistance to develop arthritis.

Taneja V, Behrens M, Basal E, Sparks J, Griffiths MM, Luthra H, David CS.

J Immunol. 2008 Aug 15;181(4):2869-77.PMID: 18684978 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA class II transgenic mice mimic human inflammatory diseases.

Mangalam AK, Rajagopalan G, Taneja V, David CS.

Adv Immunol. 2008;97:65-147. Review.PMID: 18501769 [PubMed - indexed for MEDLINE]Related articles

Cyclooxygenase 2 pathway and its therapeutic inhibition in superantigen-induced toxic shock.

Rajagopalan G, Asmann YW, Lytle AK, Tilahun AY, Theuer JE, Smart MK, Patel R, David CS.

Shock. 2008 Dec;30(6):721-8.PMID: 18496243 [PubMed - indexed for MEDLINE]Related articles

A novel H2A-E+ transgenic model susceptible to human but not mouse thyroglobulin-induced autoimmune thyroiditis: identification of mouse pathogenic epitopes.

Brown NK, McCormick DJ, Brusic V, David CS, Kong YC.

Cell Immunol. 2008 Jan;251(1):1-7. Epub 2008 Apr 14.PMID: 18489063 [PubMed - indexed for MEDLINE]Related articlesFree article

H2E-derived Ealpha52-68 peptide presented by H2Ab interferes with clonal deletion of autoreactive T cells in autoimmune thyroiditis.

Brown NK, McCormick DJ, David CS, Kong YC.

J Immunol. 2008 May 15;180(10):7039-46.PMID: 18453626 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluating the role of HLA-DQ polymorphisms on immune response to bacterial superantigens using transgenic mice.

Rajagopalan G, Polich G, Sen MM, Singh M, Epstein BE, Lytle AK, Rouse MS, Patel R, David CS.

Tissue Antigens. 2008 Feb;71(2):135-45. Epub 2007 Dec 13.PMID: 18086265 [PubMed - indexed for MEDLINE]Related articles

Gliadin-dependent neuromuscular and epithelial secretory responses in gluten-sensitive HLA-DQ8 transgenic mice.

Verdu EF, Huang X, Natividad J, Lu J, Blennerhassett PA, David CS, McKay DM, Murray JA.

Am J Physiol Gastrointest Liver Physiol. 2008 Jan;294(1):G217-25. Epub 2007 Nov 15.PMID: 18006603 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct local immunogenic stimuli dictate differential requirements for CD4+ and CD8+ T cell subsets in the pathogenesis of spontaneous autoimmune diabetes.

Rajagopalan G, Mangalam AK, Sen MM, Kudva YC, David CS.

Autoimmunity. 2007 Nov;40(7):489-96.PMID: 17966038 [PubMed - indexed for MEDLINE]Related articles

Application of HLA class II transgenic mice to study autoimmune regulation.

Kong YC, Flynn JC, Banga JP, David CS.

Thyroid. 2007 Oct;17(10):995-1003. Review.PMID: 17900224 [PubMed - indexed for MEDLINE]Related articles

Control of Her-2 tumor immunity and thyroid autoimmunity by MHC and regulatory T cells.

Jacob JB, Kong YC, Meroueh C, Snower DP, David CS, Ho YS, Wei WZ.

Cancer Res. 2007 Jul 15;67(14):7020-7.PMID: 17638915 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of haemorrhagic pulmonary capillaritis: another manifestation of Pristane-induced lupus.

Chowdhary VR, Grande JP, Luthra HS, David CS.

Rheumatology (Oxford). 2007 Sep;46(9):1405-10. Epub 2007 Jun 18.PMID: 17576695 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA-DRB1 alleles control allergic bronchopulmonary aspergillosis-like pulmonary responses in humanized transgenic mice.

Koehm S, Slavin RG, Hutcheson PS, Trejo T, David CS, Bellone CJ.

J Allergy Clin Immunol. 2007 Sep;120(3):570-7. Epub 2007 Jun 11.PMID: 17561243 [PubMed - indexed for MEDLINE]Related articles

Chronic exposure in vivo to thyrotropin receptor stimulating monoclonal antibodies sustains high thyroxine levels and thyroid hyperplasia in thyroid autoimmunity-prone HLA-DRB1*0301 transgenic mice.

Flynn JC, Gilbert JA, Meroueh C, Snower DP, David CS, Kong YC, Banga JP.

Immunology. 2007 Oct;122(2):261-7. Epub 2007 May 29.PMID: 17535305 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoimmunity in HLA-DQ8 transgenic mice expressing granulocyte/macrophage-colony stimulating factor in the beta cells of islets of Langerhans.

Rajagopalan G, Mangalam AK, Sen MM, Cheng S, Kudva YC, David CS.

Autoimmunity. 2007 May;40(3):169-79.PMID: 17453715 [PubMed - indexed for MEDLINE]Related articles

Genetic deletion of a single immunodominant T-cell response confers susceptibility to virus-induced demyelination.

Pavelko KD, Pease LR, David CS, Rodriguez M.

Brain Pathol. 2007 Apr;17(2):184-96.PMID: 17388949 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA transgenic mice provide evidence for a direct and dominant role of HLA class II variation in modulating the severity of streptococcal sepsis.

Nooh MM, El-Gengehi N, Kansal R, David CS, Kotb M.

J Immunol. 2007 Mar 1;178(5):3076-83.PMID: 17312154 [PubMed - indexed for MEDLINE]Related articlesFree article

B cells are important as antigen presenting cells for induction of MHC-restricted arthritis in transgenic mice.

Taneja V, Krco CJ, Behrens MD, Luthra HS, Griffiths MM, David CS.

Mol Immunol. 2007 Apr;44(11):2988-96. Epub 2007 Feb 14.PMID: 17303243 [PubMed - indexed for MEDLINE]Related articlesFree article

Depletion of CD4+CD25+ regulatory T cells exacerbates sodium iodide-induced experimental autoimmune thyroiditis in human leucocyte antigen DR3 (DRB1*0301) transgenic class II-knock-out non-obese diabetic mice.

Flynn JC, Meroueh C, Snower DP, David CS, Kong YM.

Clin Exp Immunol. 2007 Mar;147(3):547-54.PMID: 17302906 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA-DR3 transgenic mice immunized with adenovirus encoding the thyrotropin receptor: T cell epitopes and functional analysis of the CD40 Graves' polymorphism.

Pichurin P, Pham N, David CS, Rapoport B, McLachlan SM.

Thyroid. 2006 Dec;16(12):1221-7.PMID: 17199432 [PubMed - indexed for MEDLINE]Related articles

New humanized HLA-DR4-transgenic mice that mimic the sex bias of rheumatoid arthritis.

Taneja V, Behrens M, Mangalam A, Griffiths MM, Luthra HS, David CS.

Arthritis Rheum. 2007 Jan;56(1):69-78.PMID: 17195209 [PubMed - indexed for MEDLINE]Related articlesFree article

Comment on: Human intravenous immunoglobulin for experimental streptococcal toxic shock: bacterial clearance and modulation of inflammation.

Rajagopalan G, Patel R, Kaveri SV, David CS.

J Antimicrob Chemother. 2007 Jan;59(1):157-9; author reply 159-60. Epub 2006 Oct 28. No abstract available. PMID: 17071954 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute systemic immune activation following vaginal exposure to staphylococcal enterotoxin B--implications for menstrual shock.

Rajagopalan G, Smart MK, Murali N, Patel R, David CS.

J Reprod Immunol. 2007 Feb;73(1):51-9. Epub 2006 Oct 27.PMID: 17070600 [PubMed - indexed for MEDLINE]Related articles

Acute systemic immune activation following conjunctival exposure to staphylococcal enterotoxin B.

Rajagopalan G, Smart MK, Patel R, David CS.

Infect Immun. 2006 Oct;74(10):6016-9.PMID: 16988282 [PubMed - indexed for MEDLINE]Related articlesFree article

Mice expressing HLA-DQ6alpha8beta transgenes develop polychondritis spontaneously.

Lamoureux JL, Buckner JH, David CS, Bradley DS.

Arthritis Res Ther. 2006;8(4):R134.PMID: 16872515 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-10-deficiency unmasks unique immune system defects and reveals differential regulation of organ-specific autoimmunity in non-obese diabetic mice.

Rajagopalan G, Kudva YC, Sen MM, Marietta EV, Murali N, Nath K, Moore J, David CS.

Cytokine. 2006 Apr;34(1-2):85-95.PMID: 16740391 [PubMed - indexed for MEDLINE]Related articles

Intranasal exposure to staphylococcal enterotoxin B elicits an acute systemic inflammatory response.

Rajagopalan G, Sen MM, Singh M, Murali NS, Nath KA, Iijima K, Kita H, Leontovich AA, Gopinathan U, Patel R, David CS.

Shock. 2006 Jun;25(6):647-56.PMID: 16721274 [PubMed - indexed for MEDLINE]Related articles

Intranasal exposure to bacterial superantigens induces airway inflammation in HLA class II transgenic mice.

Rajagopalan G, Iijima K, Singh M, Kita H, Patel R, David CS.

Infect Immun. 2006 Feb;74(2):1284-96.PMID: 16428778 [PubMed - indexed for MEDLINE]Related articlesFree article

STAT4- and STAT6-signaling molecules in a murine model of multiple sclerosis.

Rodriguez M, Zoecklein L, Gamez JD, Pavelko KD, Papke LM, Nakane S, Howe C, Radhakrishnan S, Hansen MJ, David CS, Warrington AE, Pease LR.

FASEB J. 2006 Feb;20(2):343-5. Epub 2005 Dec 13.PMID: 16352646 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of immunodominant epitopes of alpha-gliadin in HLA-DQ8 transgenic mice following oral immunization.

Senger S, Maurano F, Mazzeo MF, Gaita M, Fierro O, David CS, Troncone R, Auricchio S, Siciliano RA, Rossi M.

J Immunol. 2005 Dec 15;175(12):8087-95.PMID: 16339546 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA DR and DQ interaction in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in HLA class II transgenic mice.

Khare M, Mangalam A, Rodriguez M, David CS.

J Neuroimmunol. 2005 Dec;169(1-2):1-12. Epub 2005 Sep 27.PMID: 16194572 [PubMed - indexed for MEDLINE]Related articles

HLA-DQ8 is a predisposing molecule for detergent enzyme subtilisin BPN'-induced hypersensitivity.

Xue A, Chapoval SP, Finn ES, Chowdhary VR, Marietta EV, Gaffey TA, Pursifull AC, David CS.

Clin Immunol. 2005 Dec;117(3):302-15. Epub 2005 Sep 26.PMID: 16185928 [PubMed - indexed for MEDLINE]Related articles

Endogenous superantigens shape response to exogenous superantigens.

Rajagopalan G, Singh M, Sen MM, Murali NS, Nath KA, David CS.

Clin Diagn Lab Immunol. 2005 Sep;12(9):1119-22.PMID: 16148182 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship between thyroid peroxidase T cell epitope restriction and antibody recognition of the autoantibody immunodominant region in human leukocyte antigen DR3 transgenic mice.

Guo J, McLachlan SM, Pichurin PN, Chen CR, Pham N, Aliesky HA, David CS, Rapoport B.

Endocrinology. 2005 Nov;146(11):4961-7. Epub 2005 Aug 4.PMID: 16081633 [PubMed - indexed for MEDLINE]Related articlesFree article

Toxic oil syndrome: genetic restriction and immunomodulatory effects due to adulterated oils in a model of HLA transgenic mice.

Gallardo S, Cárdaba B, Posada M, del Pozo V, Messeguer A, David CS, Lahoz C.

Toxicol Lett. 2005 Nov 15;159(2):173-81.PMID: 15979827 [PubMed - indexed for MEDLINE]Related articles

Human leukocyte antigen-DQ8 transgenic mice: a model to examine the toxicity of aerosolized staphylococcal enterotoxin B.

Roy CJ, Warfield KL, Welcher BC, Gonzales RF, Larsen T, Hanson J, David CS, Krakauer T, Bavari S.

Infect Immun. 2005 Apr;73(4):2452-60.PMID: 15784591 [PubMed - indexed for MEDLINE]Related articlesFree article

Delineation of the minimal encephalitogenic epitope of proteolipid protein peptide(91-110) and critical residues required for induction of EAE in HLA-DR3 transgenic mice.

Mangalam AK, Khare M, Krco CJ, Rodriguez M, David CS.

J Neuroimmunol. 2005 Apr;161(1-2):40-8.PMID: 15748942 [PubMed - indexed for MEDLINE]Related articles

H2A- and H2E-derived CD4+CD25+ regulatory T cells: a potential role in reciprocal inhibition by class II genes in autoimmune thyroiditis.

Morris GP, Yan Y, David CS, Kong YC.

J Immunol. 2005 Mar 1;174(5):3111-6.PMID: 15728527 [PubMed - indexed for MEDLINE]Related articlesFree article

Requirement for CD28 may not be absolute for collagen-induced arthritis: study with HLA-DQ8 transgenic mice.

Taneja V, Taneja N, Behrens M, Griffiths MM, Luthra HS, David CS.

J Immunol. 2005 Jan 15;174(2):1118-25.PMID: 15634938 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro and in vivo evaluation of staphylococcal superantigen peptide antagonists.

Rajagopalan G, Sen MM, David CS.

Infect Immun. 2004 Nov;72(11):6733-7.PMID: 15501813 [PubMed - indexed for MEDLINE]Related articlesFree article

Pathogenic human thyroglobulin peptides in HLA-DR3 transgenic mouse model of autoimmune thyroiditis.

Flynn JC, McCormick DJ, Brusic V, Wan Q, Panos JC, Giraldo AA, David CS, Kong YC.

Cell Immunol. 2004 Jun;229(2):79-85.PMID: 15474522 [PubMed - indexed for MEDLINE]Related articles

HLA-DRB1*1501 risk association in multiple sclerosis may not be related to presentation of myelin epitopes.

Finn TP, Jones RE, Rich C, Dahan R, Link J, David CS, Chou YK, Offner H, Vandenbark AA.

J Neurosci Res. 2004 Oct 1;78(1):100-14.PMID: 15372502 [PubMed - indexed for MEDLINE]Related articles