PubMed

BCL-6: a possible missing link for anti-inflammatory PPAR-delta signalling in pancreatic beta cells.

Kharroubi I, Lee CH, Hekerman P, Darville MI, Evans RM, Eizirik DL, Cnop M.

Diabetologia. 2006 Oct;49(10):2350-8. Epub 2006 Aug 5.PMID: 16896941 [PubMed - indexed for MEDLINE]Related articles

Notch signaling: a mediator of beta-cell de-differentiation in diabetes?

Darville MI, Eizirik DL.

Biochem Biophys Res Commun. 2006 Jan 27;339(4):1063-8. Epub 2005 Dec 1.PMID: 16337608 [PubMed - indexed for MEDLINE]Related articles

Macrophages enhance the radiosensitizing activity of lipid A: a novel role for immune cells in tumor cell radioresponse.

De Ridder M, Verovski VN, Darville MI, Van Den Berge DL, Monsaert C, Eizirik DL, Storme GA.

Int J Radiat Oncol Biol Phys. 2004 Oct 1;60(2):598-606.PMID: 15380597 [PubMed - indexed for MEDLINE]Related articles

An octamer motif is required for activation of the inducible nitric oxide synthase promoter in pancreatic beta-cells.

Darville MI, Terryn S, Eizirik DL.

Endocrinology. 2004 Mar;145(3):1130-6. Epub 2003 Nov 20.PMID: 14630716 [PubMed - indexed for MEDLINE]Related articlesFree article

Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells.

Kutlu B, Cardozo AK, Darville MI, Kruhøffer M, Magnusson N, Ørntoft T, Eizirik DL.

Diabetes. 2003 Nov;52(11):2701-19.PMID: 14578289 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells.

Kutlu B, Darville MI, Cardozo AK, Eizirik DL.

Diabetes. 2003 Feb;52(2):348-55.PMID: 12540607 [PubMed - indexed for MEDLINE]Related articlesFree article

Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in type 1 diabetes mellitus.

Liu D, Cardozo AK, Darville MI, Eizirik DL.

Endocrinology. 2002 Apr;143(4):1225-34.PMID: 11897677 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase.

Negoro S, Kunisada K, Fujio Y, Funamoto M, Darville MI, Eizirik DL, Osugi T, Izumi M, Oshima Y, Nakaoka Y, Hirota H, Kishimoto T, Yamauchi-Takihara K.

Circulation. 2001 Aug 28;104(9):979-81.PMID: 11524388 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokine induction of Fas gene expression in insulin-producing cells requires the transcription factors NF-kappaB and C/EBP.

Darville MI, Eizirik DL.

Diabetes. 2001 Aug;50(8):1741-8.PMID: 11473033 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular regulation of Fas expression in beta-cells.

Darville MI, Liu D, Chen MC, Eizirik DL.

Diabetes. 2001 Feb;50 Suppl 1:S83. No abstract available. PMID: 11272208 [PubMed - indexed for MEDLINE]Related articles

beta-cell apoptosis and defense mechanisms: lessons from type 1 diabetes.

Eizirik DL, Darville MI.

Diabetes. 2001 Feb;50 Suppl 1:S64-9.PMID: 11272205 [PubMed - indexed for MEDLINE]Related articles

Glutathione depletion inhibits IL-1 beta-stimulated nitric oxide production by reducing inducible nitric oxide synthase gene expression.

Nikulina MA, Andersen HU, Karlsen AE, Darville MI, Eizirik DL, Mandrup-Poulsen T.

Cytokine. 2000 Sep;12(9):1391-4.PMID: 10976000 [PubMed - indexed for MEDLINE]Related articles

NF-kappaB is required for cytokine-induced manganese superoxide dismutase expression in insulin-producing cells.

Darville MI, Ho YS, Eizirik DL.

Endocrinology. 2000 Jan;141(1):153-62.PMID: 10614634 [PubMed - indexed for MEDLINE]Related articlesFree article

Apoptosis induced by growth factor withdrawal in fibroblasts overproducing fructose 2,6-bisphosphate.

Durante P, Gueuning MA, Darville MI, Hue L, Rousseau GG.

FEBS Lett. 1999 Apr 9;448(2-3):239-43.PMID: 10218483 [PubMed - indexed for MEDLINE]Related articles

Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells.

Darville MI, Eizirik DL.

Diabetologia. 1998 Sep;41(9):1101-8.PMID: 9754830 [PubMed - indexed for MEDLINE]Related articles

E2F-dependent mitogenic stimulation of the splicing of transcripts from an S phase-regulated gene.

Darville MI, Rousseau GG.

Nucleic Acids Res. 1997 Jul 15;25(14):2759-65.PMID: 9207022 [PubMed - indexed for MEDLINE]Related articlesFree article

An E2F-dependent late-serum-response promoter in a gene that controls glycolysis.

Darville MI, Antoine IV, Mertens-Strijthagen JR, Dupriez VJ, Rousseau GG.

Oncogene. 1995 Oct 19;11(8):1509-17.PMID: 7478575 [PubMed - indexed for MEDLINE]Related articles

Characterization of the promoter of the gene encoding human tissue inhibitor of metalloproteinases-2 (TIMP-2).

De Clerck YA, Darville MI, Eeckhout Y, Rousseau GG.

Gene. 1994 Feb 25;139(2):185-91.PMID: 8112602 [PubMed - indexed for MEDLINE]Related articles

Characterization of a hepatoma mRNA transcribed from a third promoter of a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-encoding gene and controlled by ets oncogene-related products.

Dupriez VJ, Darville MI, Antoine IV, Gegonne A, Ghysdael J, Rousseau GG.

Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):8224-8.PMID: 8396265 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of an enhancer upstream from the muscle-type promoter of a gene encoding 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Darville MI, Antoine IV, Rousseau GG.

Nucleic Acids Res. 1992 Jul 25;20(14):3575-83.PMID: 1322527 [PubMed - indexed for MEDLINE]Related articlesFree article

A rat gene encoding heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Darville MI, Chikri M, Lebeau E, Hue L, Rousseau GG.

FEBS Lett. 1991 Aug 19;288(1-2):91-4.PMID: 1652483 [PubMed - indexed for MEDLINE]Related articles

Human and rat chromosomal localization of two genes for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by analysis of somatic cell hybrids and in situ hybridization.

Hilliker CE, Darville MI, Aly MS, Chikri M, Szpirer C, Marynen P, Rousseau GG, Cassiman JJ.

Genomics. 1991 Aug;10(4):867-73.PMID: 1655632 [PubMed - indexed for MEDLINE]Related articles

Cloning and expression in Escherichia coli of a rat hepatoma cell cDNA coding for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Crepin KM, Darville MI, Michel A, Hue L, Rousseau GG.

Biochem J. 1989 Nov 15;264(1):151-60.PMID: 2557826 [PubMed - indexed for MEDLINE]Related articlesFree article

5' flanking sequence and structure of a gene encoding rat 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Darville MI, Crepin KM, Hue L, Rousseau GG.

Proc Natl Acad Sci U S A. 1989 Sep;86(17):6543-7.PMID: 2549541 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of distinct mRNAs coding for putative isozymes of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Crepin KM, Darville MI, Hue L, Rousseau GG.

Eur J Biochem. 1989 Aug 1;183(2):433-40.PMID: 2547611 [PubMed - indexed for MEDLINE]Related articlesFree article

Starvation or diabetes decreases the content but not the mRNA of 6-phosphofructo-2-kinase in rat liver.

Crepin KM, Darville MI, Hue L, Rousseau GG.

FEBS Lett. 1988 Jan 25;227(2):136-40.PMID: 2962885 [PubMed - indexed for MEDLINE]Related articles

Complete nucleotide sequence coding for rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase derived from a cDNA clone.

Darville MI, Crepin KM, Vandekerckhove J, Van Damme J, Octave JN, Rider MH, Marchand MJ, Hue L, Rousseau GG.

FEBS Lett. 1987 Nov 30;224(2):317-21.PMID: 2856848 [PubMed - indexed for MEDLINE]Related articles