PubMed

Focus on FOCIS: the continuing diagnostic challenge of autosomal recessive chronic granulomatous disease.

Yu G, Hong DK, Dionis KY, Rae J, Heyworth PG, Curnutte JT, Lewis DB.

Clin Immunol. 2008 Aug;128(2):117-26.PMID: 18625437 [PubMed - indexed for MEDLINE]Related articles

Recurrent streptococcal hepatic abscesses in a 46-year-old woman.

Lo R, Rae J, Noack D, Curnutte JT, Avila PC.

Ann Allergy Asthma Immunol. 2005 Oct;95(4):325-9. No abstract available. PMID: 16279561 [PubMed - indexed for MEDLINE]Related articles

Superoxide production by phagocytic leukocytes: the scientific legacy of Bernard Babior.

Curnutte JT.

J Clin Invest. 2004 Oct;114(8):1054-7.PMID: 15489952 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic granulomatous disease caused by a deficiency in p47(phox) mimicking Crohn's disease.

Huang JS, Noack D, Rae J, Ellis BA, Newbury R, Pong AL, Lavine JE, Curnutte JT, Bastian J.

Clin Gastroenterol Hepatol. 2004 Aug;2(8):690-5.PMID: 15290662 [PubMed - indexed for MEDLINE]Related articles

Chronic granulomatous disease.

Heyworth PG, Cross AR, Curnutte JT.

Curr Opin Immunol. 2003 Oct;15(5):578-84. Review.PMID: 14499268 [PubMed - indexed for MEDLINE]Related articles

Diminished T cell numbers in patients with chronic granulomatous disease.

Heltzer M, Jawad AF, Rae J, Curnutte JT, Sullivan KE.

Clin Immunol. 2002 Dec;105(3):273-8.PMID: 12498808 [PubMed - indexed for MEDLINE]Related articles

Complement-induced impairment of innate immunity during sepsis.

Huber-Lang MS, Younkin EM, Sarma JV, McGuire SR, Lu KT, Guo RF, Padgaonkar VA, Curnutte JT, Erickson R, Ward PA.

J Immunol. 2002 Sep 15;169(6):3223-31.PMID: 12218141 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of gp91-phox, a component of the phagocyte NADPH oxidase, in microglial cells during central nervous system inflammation.

Green SP, Cairns B, Rae J, Errett-Baroncini C, Hongo JA, Erickson RW, Curnutte JT.

J Cereb Blood Flow Metab. 2001 Apr;21(4):374-84.PMID: 11323523 [PubMed - indexed for MEDLINE]Related articlesFree article

Transplantation of a fetus with paternal Thy-1(+)CD34(+)cells for chronic granulomatous disease.

Muench MO, Rae J, Bárcena A, Leemhuis T, Farrell J, Humeau L, Maxwell-Wiggins JR, Capper J, Mychaliska GB, Albanese CT, Martin T, Tsukamoto A, Curnutte JT, Harrison MR.

Bone Marrow Transplant. 2001 Feb;27(4):355-64.PMID: 11313664 [PubMed - indexed for MEDLINE]Related articlesFree article

Hematologically important mutations: X-linked chronic granulomatous disease (second update).

Heyworth PG, Curnutte JT, Rae J, Noack D, Roos D, van Koppen E, Cross AR.

Blood Cells Mol Dis. 2001 Jan-Feb;27(1):16-26. No abstract available. PMID: 11162142 [PubMed - indexed for MEDLINE]Related articles

Role of C5a in multiorgan failure during sepsis.

Huber-Lang M, Sarma VJ, Lu KT, McGuire SR, Padgaonkar VA, Guo RF, Younkin EM, Kunkel RG, Ding J, Erickson R, Curnutte JT, Ward PA.

J Immunol. 2001 Jan 15;166(2):1193-9.PMID: 11145701 [PubMed - indexed for MEDLINE]Related articlesFree article

Autosomal recessive chronic granulomatous disease caused by defects in NCF-1, the gene encoding the phagocyte p47-phox: mutations not arising in the NCF-1 pseudogenes.

Noack D, Rae J, Cross AR, Ellis BA, Newburger PE, Curnutte JT, Heyworth PG.

Blood. 2001 Jan 1;97(1):305-11.PMID: 11133775 [PubMed - indexed for MEDLINE]Related articlesFree article

Hematologically important mutations: the autosomal recessive forms of chronic granulomatous disease (first update).

Cross AR, Noack D, Rae J, Curnutte JT, Heyworth PG.

Blood Cells Mol Dis. 2000 Oct;26(5):561-5. Review. No abstract available. PMID: 11112388 [PubMed - indexed for MEDLINE]Related articles

Experimental histoplasmosis in mice treated with anti-murine interferon-gamma antibody and in interferon-gamma gene knockout mice.

Clemons KV, Darbonne WC, Curnutte JT, Sobel RA, Stevens DA.

Microbes Infect. 2000 Jul;2(9):997-1001.PMID: 10967280 [PubMed - indexed for MEDLINE]Related articles

Molecular analysis of 9 new families with chronic granulomatous disease caused by mutations in CYBA, the gene encoding p22(phox).

Rae J, Noack D, Heyworth PG, Ellis BA, Curnutte JT, Cross AR.

Blood. 2000 Aug 1;96(3):1106-12.PMID: 10910929 [PubMed - indexed for MEDLINE]Related articlesFree article

Genomic structure of the human p47-phox (NCF1) gene.

Chanock SJ, Roesler J, Zhan S, Hopkins P, Lee P, Barrett DT, Christensen BL, Curnutte JT, Görlach A.

Blood Cells Mol Dis. 2000 Feb;26(1):37-46.PMID: 10772875 [PubMed - indexed for MEDLINE]Related articles

Recombination events between the p47-phox gene and its highly homologous pseudogenes are the main cause of autosomal recessive chronic granulomatous disease.

Roesler J, Curnutte JT, Rae J, Barrett D, Patino P, Chanock SJ, Goerlach A.

Blood. 2000 Mar 15;95(6):2150-6.PMID: 10706888 [PubMed - indexed for MEDLINE]Related articlesFree article

Autosomal recessive chronic granulomatous disease caused by novel mutations in NCF-2, the gene encoding the p67-phox component of phagocyte NADPH oxidase.

Noack D, Rae J, Cross AR, Muñoz J, Salmen S, Mendoza JA, Rossi N, Curnutte JT, Heyworth PG.

Hum Genet. 1999 Nov;105(5):460-7.PMID: 10598813 [PubMed - indexed for MEDLINE]Related articles

Molecular characterization of autosomal recessive chronic granulomatous disease caused by a defect of the nicotinamide adenine dinucleotide phosphate (reduced form) oxidase component p67-phox.

Patiño PJ, Rae J, Noack D, Erickson R, Ding J, de Olarte DG, Curnutte JT.

Blood. 1999 Oct 1;94(7):2505-14.PMID: 10498624 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel mutation in the CYBB gene resulting in an unexpected pattern of exon skipping and chronic granulomatous disease.

Noack D, Heyworth PG, Curnutte JT, Rae J, Cross AR.

Biochim Biophys Acta. 1999 Aug 30;1454(3):270-4.PMID: 10452961 [PubMed - indexed for MEDLINE]Related articles

Activation of human neutrophil NADPH oxidase by phosphatidic acid or diacylglycerol in a cell-free system. Activity of diacylglycerol is dependent on its conversion to phosphatidic acid.

Erickson RW, Langel-Peveri P, Traynor-Kaplan AE, Heyworth PG, Curnutte JT.

J Biol Chem. 1999 Aug 6;274(32):22243-50.PMID: 10428791 [PubMed - indexed for MEDLINE]Related articlesFree article

The mechanism of activation of NADPH oxidase in the cell-free system: the activation process is primarily catalytic and not through the formation of a stoichiometric complex.

Cross AR, Erickson RW, Curnutte JT.

Biochem J. 1999 Jul 15;341 ( Pt 2):251-5.PMID: 10393079 [PubMed - indexed for MEDLINE]Related articlesFree article

Simultaneous presence of p47(phox) and flavocytochrome b-245 are required for the activation of NADPH oxidase by anionic amphiphiles. Evidence for an intermediate state of oxidase activation.

Cross AR, Erickson RW, Curnutte JT.

J Biol Chem. 1999 May 28;274(22):15519-25.PMID: 10336445 [PubMed - indexed for MEDLINE]Related articlesFree article

Spontaneous activation of NADPH oxidase in a cell-free system: unexpected multiple effects of magnesium ion concentrations.

Cross AR, Erickson RW, Ellis BA, Curnutte JT.

Biochem J. 1999 Feb 15;338 ( Pt 1):229-33.PMID: 9931320 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular analysis of chronic granulomatous disease caused by defects in gp91-phox.

Patiño PJ, Perez JE, Lopez JA, Condino-Neto A, Grumach AS, Botero JH, Curnutte JT, García de Olarte D.

Hum Mutat. 1999;13(1):29-37.PMID: 9888386 [PubMed - indexed for MEDLINE]Related articles

Host defense molecule polymorphisms influence the risk for immune-mediated complications in chronic granulomatous disease.

Foster CB, Lehrnbecher T, Mol F, Steinberg SM, Venzon DJ, Walsh TJ, Noack D, Rae J, Winkelstein JA, Curnutte JT, Chanock SJ.

J Clin Invest. 1998 Dec 15;102(12):2146-55.PMID: 9854050 [PubMed - indexed for MEDLINE]Related articlesFree article

X-Linked chronic granulomatous disease: mutations in the CYBB gene encoding the gp91-phox component of respiratory-burst oxidase.

Rae J, Newburger PE, Dinauer MC, Noack D, Hopkins PJ, Kuruto R, Curnutte JT.

Am J Hum Genet. 1998 Jun;62(6):1320-31.PMID: 9585602 [PubMed - indexed for MEDLINE]Related articlesFree article

Hematologically important mutations: X-linked chronic granulomatous disease--an update.

Heyworth PG, Curnutte JT, Noack D, Cross AR.

Blood Cells Mol Dis. 1997 Dec;23(3):443-50. No abstract available. PMID: 9454688 [PubMed - indexed for MEDLINE]Related articles

Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase.

Walder CE, Green SP, Darbonne WC, Mathias J, Rae J, Dinauer MC, Curnutte JT, Thomas GR.

Stroke. 1997 Nov;28(11):2252-8.PMID: 9368573 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased phagocyte Fc gammaRI expression and improved Fc gamma-receptor-mediated phagocytosis after in vivo recombinant human interferon-gamma treatment of normal human subjects.

Schiff DE, Rae J, Martin TR, Davis BH, Curnutte JT.

Blood. 1997 Oct 15;90(8):3187-94.PMID: 9376602 [PubMed - indexed for MEDLINE]Related articlesFree article

A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease.

Görlach A, Lee PL, Roesler J, Hopkins PJ, Christensen B, Green ED, Chanock SJ, Curnutte JT.

J Clin Invest. 1997 Oct 15;100(8):1907-18.PMID: 9329953 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunocytochemical localization on O2-sensing protein (NADPH oxidase) in chemoreceptor cells.

Youngson C, Nurse C, Yeger H, Curnutte JT, Vollmer C, Wong V, Cutz E.

Microsc Res Tech. 1997 Apr 1;37(1):101-6.PMID: 9144626 [PubMed - indexed for MEDLINE]Related articles

Interleukin-8 (IL-8), melanoma growth-stimulatory activity, and neutrophil-activating peptide selectively mediate priming of the neutrophil NADPH oxidase through the type A or type B IL-8 receptor.

Green SP, Chuntharapai A, Curnutte JT.

J Biol Chem. 1996 Oct 11;271(41):25400-5.PMID: 8810307 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein phosphorylation in neutrophils from patients with p67-phox-deficient chronic granulomatous disease.

Heyworth PG, Ding J, Erickson RW, Lu DJ, Curnutte JT, Badwey JA.

Blood. 1996 May 15;87(10):4404-10.PMID: 8639802 [PubMed - indexed for MEDLINE]Related articlesFree article

Hematologically important mutations: the autosomal recessive forms of chronic granulomatous disease.

Cross AR, Curnutte JT, Heyworth PG.

Blood Cells Mol Dis. 1996;22(3):268-70. No abstract available. PMID: 9075578 [PubMed - indexed for MEDLINE]Related articles

Hematologically important mutations: X-linked chronic granulomatous disease.

Cross AR, Curnutte JT, Rae J, Heyworth PG.

Blood Cells Mol Dis. 1996;22(1):90-5. No abstract available. PMID: 8807090 [PubMed - indexed for MEDLINE]Related articles

Naphthalenesulphonamides block neutrophil superoxide production by intact cells and in a cell-free system: is myosin light chain kinase responsible for these effects?

Heyworth PG, Erickson RW, Ding J, Curnutte JT, Badwey JA.

Biochem J. 1995 Oct 1;311 ( Pt 1):81-7.PMID: 7575484 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytochrome b-245 of the neutrophil superoxide-generating system contains two nonidentical hemes. Potentiometric studies of a mutant form of gp91phox.

Cross AR, Rae J, Curnutte JT.

J Biol Chem. 1995 Jul 21;270(29):17075-7.PMID: 7615499 [PubMed - indexed for MEDLINE]Related articlesFree article

A variant X-linked chronic granulomatous disease patient (X91+) with partially functional cytochrome b.

Cross AR, Heyworth PG, Rae J, Curnutte JT.

J Biol Chem. 1995 Apr 7;270(14):8194-200. Erratum in: J Biol Chem 1995 Jul 14;270(28):17056. PMID: 7713925 [PubMed - indexed for MEDLINE]Related articlesFree article

The cytosolic activating factors p47phox and p67phox have distinct roles in the regulation of electron flow in NADPH oxidase.

Cross AR, Curnutte JT.

J Biol Chem. 1995 Mar 24;270(12):6543-8.PMID: 7896790 [PubMed - indexed for MEDLINE]Related articlesFree article

Safety and effectiveness of long-term interferon gamma therapy in patients with chronic granulomatous disease.

Bemiller LS, Roberts DH, Starko KM, Curnutte JT.

Blood Cells Mol Dis. 1995;21(3):239-47.PMID: 8673477 [PubMed - indexed for MEDLINE]Related articles

A new X-linked variant of chronic granulomatous disease characterized by the existence of a normal clone of respiratory burst-competent phagocytic cells.

Woodman RC, Newburger PE, Anklesaria P, Erickson RW, Rae J, Cohen MS, Curnutte JT.

Blood. 1995 Jan 1;85(1):231-41.PMID: 7803797 [PubMed - indexed for MEDLINE]Related articlesFree article

Rac translocates independently of the neutrophil NADPH oxidase components p47phox and p67phox. Evidence for its interaction with flavocytochrome b558.

Heyworth PG, Bohl BP, Bokoch GM, Curnutte JT.

J Biol Chem. 1994 Dec 9;269(49):30749-52.PMID: 7982999 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic granulomatous disease and glutathione peroxidase deficiency, revisited.

Newburger PE, Malawista SE, Dinauer MC, Gelbart T, Woodman RC, Chada S, Shen Q, van Blaricom G, Quie PG, Curnutte JT.

Blood. 1994 Dec 1;84(11):3861-9.PMID: 7949143 [PubMed - indexed for MEDLINE]Related articlesFree article

Infection with Pseudomonas cepacia in chronic granulomatous disease: role of nonoxidative killing by neutrophils in host defense.

Speert DP, Bond M, Woodman RC, Curnutte JT.

J Infect Dis. 1994 Dec;170(6):1524-31.PMID: 7527826 [PubMed - indexed for MEDLINE]Related articles

Assessment of the contribution of the cytochrome b moiety of the NADPH oxidase to the transmembrane H+ conductance of leukocytes.

Nanda A, Romanek R, Curnutte JT, Grinstein S.

J Biol Chem. 1994 Nov 4;269(44):27280-5.PMID: 7525551 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutations in the promoter region of the gene for gp91-phox in X-linked chronic granulomatous disease with decreased expression of cytochrome b558.

Newburger PE, Skalnik DG, Hopkins PJ, Eklund EA, Curnutte JT.

J Clin Invest. 1994 Sep;94(3):1205-11.PMID: 8083361 [PubMed - indexed for MEDLINE]Related articlesFree article

Myeloid haemopoietic cells of patients with chronic granulomatous disease are relatively resistant to TNF.

Sakashita A, Curnutte JT, Koeffler HP.

Br J Haematol. 1994 Sep;88(1):31-8.PMID: 7803254 [PubMed - indexed for MEDLINE]Related articles

The superoxide-generating system of human neutrophils possesses a novel diaphorase activity. Evidence for distinct regulation of electron flow within NADPH oxidase by p67-phox and p47-phox.

Cross AR, Yarchover JL, Curnutte JT.

J Biol Chem. 1994 Aug 26;269(34):21448-54.PMID: 8063777 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of a H(+)-selective conductance during granulocytic differentiation of HL-60 cells.

Qu AY, Nanda A, Curnutte JT, Grinstein S.

Am J Physiol. 1994 May;266(5 Pt 1):C1263-70.PMID: 8203491 [PubMed - indexed for MEDLINE]Related articles