PubMed

Identification of an exonic splicing silencer in exon 6A of the human VEGF gene.

Wang R, Crystal RG, Hackett NR.

BMC Mol Biol. 2009 Nov 17;10(1):103. [Epub ahead of print]PMID: 19922608 [PubMed - as supplied by publisher]Related articlesFree article

Disparate oxidant gene expression of airway epithelium compared to alveolar macrophages in smokers.

Carolan BJ, Harvey BG, Hackett NR, O'Connor TP, Cassano PA, Crystal RG.

Respir Res. 2009 Nov 17;10(1):111. [Epub ahead of print]PMID: 19919714 [PubMed - as supplied by publisher]Related articlesFree article

Quality control in microarray assessment of gene expression in human airway epithelium.

Raman T, O'Connor TP, Hackett NR, Wang W, Harvey BG, Attiyeh MA, Dang DT, Teater M, Crystal RG.

BMC Genomics. 2009 Oct 24;10:493.PMID: 19852842 [PubMed - in process]Related articlesFree article

Adenovirus Vectors Block HIV-1 Replication in Human Alveolar Macrophages by Inhibition of the LTR.

Kaner RJ, Santiago F, Rahaghi F, Michaels E, Moore JP, Crystal RG.

Am J Respir Cell Mol Biol. 2009 Oct 5. [Epub ahead of print]PMID: 19805482 [PubMed - as supplied by publisher]Related articles

Translating stem cell therapy to the clinic: déjà vu all over again.

Crystal RG.

Mol Ther. 2009 Oct;17(10):1659-60. No abstract available. PMID: 19789557 [PubMed - in process]Related articles

Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease.

Shaykhiev R, Krause A, Salit J, Strulovici-Barel Y, Harvey BG, O'Connor TP, Crystal RG.

J Immunol. 2009 Aug 15;183(4):2867-83. Epub 2009 Jul 27.PMID: 19635926 [PubMed - indexed for MEDLINE]Related articles

Up-regulation of alveolar macrophage matrix metalloproteinases in HIV1(+) smokers with early emphysema.

Kaner RJ, Santiago F, Crystal RG.

J Leukoc Biol. 2009 Oct;86(4):913-22. Epub 2009 Jul 15.PMID: 19605697 [PubMed - indexed for MEDLINE]Related articles

A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition.

Vincent T, Neve EP, Johnson JR, Kukalev A, Rojo F, Albanell J, Pietras K, Virtanen I, Philipson L, Leopold PL, Crystal RG, de Herreros AG, Moustakas A, Pettersson RF, Fuxe J.

Nat Cell Biol. 2009 Aug;11(8):943-50. Epub 2009 Jul 13.PMID: 19597490 [PubMed - indexed for MEDLINE]Related articles

Coordinate control of expression of Nrf2-modulated genes in the human small airway epithelium is highly responsive to cigarette smoking.

Hübner RH, Schwartz JD, De Bishnu P, Ferris B, Omberg L, Mezey JG, Hackett NR, Crystal RG.

Mol Med. 2009 Jul-Aug;15(7-8):203-19. Epub 2009 Mar 20.PMID: 19593404 [PubMed - indexed for MEDLINE]Related articlesFree article

Sonic hedgehog expands diaphyseal trabecular bone altering bone marrow niche and lymphocyte compartment.

Kiuru M, Hidaka C, Hubner RH, Solomon J, Krause A, Leopold PL, Crystal RG.

Mol Ther. 2009 Aug;17(8):1442-52. Epub 2009 May 12.PMID: 19436267 [PubMed - indexed for MEDLINE]Related articles

Expression of B-cell activating factor enhances protective immunity of a vaccine against Pseudomonas aeruginosa.

Tertilt C, Joh J, Krause A, Chou P, Schneeweiss K, Crystal RG, Worgall S.

Infect Immun. 2009 Jul;77(7):3044-55. Epub 2009 Apr 13.PMID: 19364838 [PubMed - indexed for MEDLINE]Related articles

Influence of the cystic fibrosis transmembrane conductance regulator on expression of lipid metabolism-related genes in dendritic cells.

Xu Y, Tertilt C, Krause A, Quadri LE, Crystal RG, Worgall S.

Respir Res. 2009 Apr 3;10:26.PMID: 19344509 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic control of wayward pluripotent stem cells and their progeny after transplantation.

Kiuru M, Boyer JL, O'Connor TP, Crystal RG.

Cell Stem Cell. 2009 Apr 3;4(4):289-300.PMID: 19341619 [PubMed - indexed for MEDLINE]Related articles

Transient overexpression of sonic hedgehog alters the architecture and mechanical properties of trabecular bone.

Kiuru M, Solomon J, Ghali B, van der Meulen M, Crystal RG, Hidaka C.

J Bone Miner Res. 2009 Sep;24(9):1598-607.PMID: 19338448 [PubMed - in process]Related articles

Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing.

Song Y, Lou HH, Boyer JL, Limberis MP, Vandenberghe LH, Hackett NR, Leopold PL, Wilson JM, Crystal RG.

Hum Gene Ther. 2009 Mar;20(3):267-81.PMID: 19257851 [PubMed - indexed for MEDLINE]Related articles

Genetic delivery of bevacizumab to suppress vascular endothelial growth factor-induced high-permeability pulmonary edema.

Watanabe M, Boyer JL, Crystal RG.

Hum Gene Ther. 2009 Jun;20(6):598-610.PMID: 19254174 [PubMed - indexed for MEDLINE]Related articles

Cigarette smoking induces overexpression of a fat-depleting gene AZGP1 in the human.

Vanni H, Kazeros A, Wang R, Harvey BG, Ferris B, De BP, Carolan BJ, Hübner RH, O'Connor TP, Crystal RG.

Chest. 2009 May;135(5):1197-208. Epub 2009 Feb 2.PMID: 19188554 [PubMed - indexed for MEDLINE]Related articles

Adenovirus-mediated delivery of an anti-V antigen monoclonal antibody protects mice against a lethal Yersinia pestis challenge.

Sofer-Podesta C, Ang J, Hackett NR, Senina S, Perlin D, Crystal RG, Boyer JL.

Infect Immun. 2009 Apr;77(4):1561-8. Epub 2009 Jan 5.PMID: 19124600 [PubMed - indexed for MEDLINE]Related articlesFree article

Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease.

Tilley AE, Harvey BG, Heguy A, Hackett NR, Wang R, O'Connor TP, Crystal RG.

Am J Respir Crit Care Med. 2009 Mar 15;179(6):457-66. Epub 2008 Dec 23.PMID: 19106307 [PubMed - indexed for MEDLINE]Related articles

Decreased expression of intelectin 1 in the human airway epithelium of smokers compared to nonsmokers.

Carolan BJ, Harvey BG, De BP, Vanni H, Crystal RG.

J Immunol. 2008 Oct 15;181(8):5760-7.PMID: 18832735 [PubMed - indexed for MEDLINE]Related articlesFree article

Airway epithelial cells: current concepts and challenges.

Crystal RG, Randell SH, Engelhardt JF, Voynow J, Sunday ME.

Proc Am Thorac Soc. 2008 Sep 15;5(7):772-7. Review.PMID: 18757316 [PubMed - indexed for MEDLINE]Related articlesFree article

Resident cellular components of the human lung: current knowledge and goals for research on cell phenotyping and function.

Franks TJ, Colby TV, Travis WD, Tuder RM, Reynolds HY, Brody AR, Cardoso WV, Crystal RG, Drake CJ, Engelhardt J, Frid M, Herzog E, Mason R, Phan SH, Randell SH, Rose MC, Stevens T, Serge J, Sunday ME, Voynow JA, Weinstein BM, Whitsett J, Williams MC.

Proc Am Thorac Soc. 2008 Sep 15;5(7):763-6.PMID: 18757314 [PubMed - indexed for MEDLINE]Related articlesFree article

Dysfunctional glycogen storage in a mouse model of alpha1-antitrypsin deficiency.

Hubner RH, Leopold PL, Kiuru M, De BP, Krause A, Crystal RG.

Am J Respir Cell Mol Biol. 2009 Feb;40(2):239-47. Epub 2008 Aug 7.PMID: 18688041 [PubMed - indexed for MEDLINE]Related articles

Survival advantage of neonatal CNS gene transfer for late infantile neuronal ceroid lipofuscinosis.

Sondhi D, Peterson DA, Edelstein AM, del Fierro K, Hackett NR, Crystal RG.

Exp Neurol. 2008 Sep;213(1):18-27. Epub 2008 Apr 30.PMID: 18639872 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of apoptotic cell removal receptor MERTK in alveolar macrophages of cigarette smokers.

Kazeros A, Harvey BG, Carolan BJ, Vanni H, Krause A, Crystal RG.

Am J Respir Cell Mol Biol. 2008 Dec;39(6):747-57. Epub 2008 Jun 27.PMID: 18587056 [PubMed - indexed for MEDLINE]Related articles

Genetic delivery of an anti-RSV antibody to protect against pulmonary infection with RSV.

Skaricic D, Traube C, De B, Joh J, Boyer J, Crystal RG, Worgall S.

Virology. 2008 Aug 15;378(1):79-85. Epub 2008 Jun 16.PMID: 18556039 [PubMed - indexed for MEDLINE]Related articles

Genetic medicine strategies to protect against bioterrorism.

Boyer JL, Crystal RG.

Trans Am Clin Climatol Assoc. 2006;117:297-310; discussion 310-1. Review. No abstract available. PMID: 18528482 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of late infantile neuronal ceroid lipofuscinosis by CNS administration of a serotype 2 adeno-associated virus expressing CLN2 cDNA.

Worgall S, Sondhi D, Hackett NR, Kosofsky B, Kekatpure MV, Neyzi N, Dyke JP, Ballon D, Heier L, Greenwald BM, Christos P, Mazumdar M, Souweidane MM, Kaplitt MG, Crystal RG.

Hum Gene Ther. 2008 May;19(5):463-74.PMID: 18473686 [PubMed - indexed for MEDLINE]Related articles

Variability in small airway epithelial gene expression among normal smokers.

Ammous Z, Hackett NR, Butler MW, Raman T, Dolgalev I, O'Connor TP, Harvey BG, Crystal RG.

Chest. 2008 Jun;133(6):1344-53. Epub 2008 Mar 13.PMID: 18339782 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic delivery of the murine equivalent of bevacizumab (avastin), an anti-vascular endothelial growth factor monoclonal antibody, to suppress growth of human tumors in immunodeficient mice.

Watanabe M, Boyer JL, Hackett NR, Qiu J, Crystal RG.

Hum Gene Ther. 2008 Mar;19(3):300-10.PMID: 18324912 [PubMed - indexed for MEDLINE]Related articles

Progress and prospects: gene therapy for performance and appearance enhancement.

Kiuru M, Crystal RG.

Gene Ther. 2008 Mar;15(5):329-37. Epub 2008 Jan 24. Review.PMID: 18283287 [PubMed - indexed for MEDLINE]Related articles

Rapid/sustained anti-anthrax passive immunity mediated by co-administration of Ad/AAV.

De BP, Hackett NR, Crystal RG, Boyer JL.

Mol Ther. 2008 Jan;16(1):203-9. Epub 2007 Dec 4.PMID: 18059375 [PubMed - indexed for MEDLINE]Related articles

Ablation of tumor-derived stem cells transplanted to the central nervous system by genetic modification of embryonic stem cells with a suicide gene.

Jung J, Hackett NR, Pergolizzi RG, Pierre-Destine L, Krause A, Crystal RG.

Hum Gene Ther. 2007 Dec;18(12):1182-92.PMID: 18021021 [PubMed - indexed for MEDLINE]Related articles

Protective immunity to pseudomonas aeruginosa induced with a capsid-modified adenovirus expressing P. aeruginosa OprF.

Worgall S, Krause A, Qiu J, Joh J, Hackett NR, Crystal RG.

J Virol. 2007 Dec;81(24):13801-8. Epub 2007 Oct 17.PMID: 17942539 [PubMed - indexed for MEDLINE]Related articlesFree article

Intracellular trafficking of adenovirus: many means to many ends.

Leopold PL, Crystal RG.

Adv Drug Deliv Rev. 2007 Aug 10;59(8):810-21. Epub 2007 Jun 28. Review.PMID: 17707546 [PubMed - indexed for MEDLINE]Related articles

Assessing disease severity in late infantile neuronal ceroid lipofuscinosis using quantitative MR diffusion-weighted imaging.

Dyke JP, Voss HU, Sondhi D, Hackett NR, Worgall S, Heier LA, Kosofsky BE, Uluğ AM, Shungu DC, Mao X, Crystal RG, Ballon D.

AJNR Am J Neuroradiol. 2007 Aug;28(7):1232-6.PMID: 17698521 [PubMed - indexed for MEDLINE]Related articlesFree article

Neurological deterioration in late infantile neuronal ceroid lipofuscinosis.

Worgall S, Kekatpure MV, Heier L, Ballon D, Dyke JP, Shungu D, Mao X, Kosofsky B, Kaplitt MG, Souweidane MM, Sondhi D, Hackett NR, Hollmann C, Crystal RG.

Neurology. 2007 Aug 7;69(6):521-35.PMID: 17679671 [PubMed - indexed for MEDLINE]Related articles

Human embryonic stem cells and gene therapy.

Strulovici Y, Leopold PL, O'Connor TP, Pergolizzi RG, Crystal RG.

Mol Ther. 2007 May;15(5):850-66. Epub 2007 Mar 20. Review.PMID: 17356540 [PubMed - indexed for MEDLINE]Related articles

Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis.

Gelbman BD, Heguy A, O'Connor TP, Zabner J, Crystal RG.

Respir Res. 2007 Feb 8;8:10.PMID: 17288615 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction of Pneumocystis carinii with dendritic cells and resulting host responses to P. carinii.

Kobayashi H, Worgall S, O'Connor TP, Crystal RG.

J Immunother. 2007 Jan;30(1):54-63.PMID: 17198083 [PubMed - indexed for MEDLINE]Related articles

Enhanced survival of the LINCL mouse following CLN2 gene transfer using the rh.10 rhesus macaque-derived adeno-associated virus vector.

Sondhi D, Hackett NR, Peterson DA, Stratton J, Baad M, Travis KM, Wilson JM, Crystal RG.

Mol Ther. 2007 Mar;15(3):481-91. Epub 2006 Dec 19.PMID: 17180118 [PubMed - indexed for MEDLINE]Related articles

Responses of the human airway epithelium transcriptome to in vivo injury.

Heguy A, Harvey BG, Leopold PL, Dolgalev I, Raman T, Crystal RG.

Physiol Genomics. 2007 Apr 24;29(2):139-48. Epub 2006 Dec 12.PMID: 17164391 [PubMed - indexed for MEDLINE]Related articlesFree article

Modification of gene expression of the small airway epithelium in response to cigarette smoking.

Harvey BG, Heguy A, Leopold PL, Carolan BJ, Ferris B, Crystal RG.

J Mol Med. 2007 Jan;85(1):39-53. Epub 2006 Nov 8. Erratum in: J Mol Med. 2008 Jul;86(7):853. PMID: 17115125 [PubMed - indexed for MEDLINE]Related articles

Up-regulation of expression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers.

Carolan BJ, Heguy A, Harvey BG, Leopold PL, Ferris B, Crystal RG.

Cancer Res. 2006 Nov 15;66(22):10729-40.PMID: 17108109 [PubMed - indexed for MEDLINE]Related articlesFree article

The Gordon Wilson lecture: using genetic medicine to regenerate diseased organs and protect against the hostile environment.

O'Connor TP, Crystal RG.

Trans Am Clin Climatol Assoc. 2004;115:163-83. No abstract available. PMID: 17060966 [PubMed - indexed for MEDLINE]Related articlesFree article

Protective immunity against respiratory tract challenge with Yersinia pestis in mice immunized with an adenovirus-based vaccine vector expressing V antigen.

Chiuchiolo MJ, Boyer JL, Krause A, Senina S, Hackett NR, Crystal RG.

J Infect Dis. 2006 Nov 1;194(9):1249-57. Epub 2006 Sep 25.PMID: 17041851 [PubMed - indexed for MEDLINE]Related articles

Neutralized adenovirus-immune complexes can mediate effective gene transfer via an Fc receptor-dependent infection pathway.

Leopold PL, Wendland RL, Vincent T, Crystal RG.

J Virol. 2006 Oct;80(20):10237-47.PMID: 17005701 [PubMed - indexed for MEDLINE]Related articlesFree article

A common mechanism for cytoplasmic dynein-dependent microtubule binding shared among adeno-associated virus and adenovirus serotypes.

Kelkar S, De BP, Gao G, Wilson JM, Crystal RG, Leopold PL.

J Virol. 2006 Aug;80(15):7781-5.PMID: 16840360 [PubMed - indexed for MEDLINE]Related articlesFree article

Epitopes expressed in different adenovirus capsid proteins induce different levels of epitope-specific immunity.

Krause A, Joh JH, Hackett NR, Roelvink PW, Bruder JT, Wickham TJ, Kovesdi I, Crystal RG, Worgall S.

J Virol. 2006 Jun;80(11):5523-30.PMID: 16699033 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes.

Jin DK, Shido K, Kopp HG, Petit I, Shmelkov SV, Young LM, Hooper AT, Amano H, Avecilla ST, Heissig B, Hattori K, Zhang F, Hicklin DJ, Wu Y, Zhu Z, Dunn A, Salari H, Werb Z, Hackett NR, Crystal RG, Lyden D, Rafii S.

Nat Med. 2006 May;12(5):557-67. Epub 2006 Apr 30. Erratum in: Nat Med. 2006 Aug;12(8):978. PMID: 16648859 [PubMed - indexed for MEDLINE]Related articlesFree article