PubMed

Beta-Cell-Mediated Signaling Predominates Over Direct Alpha-Cell Signaling in the Regulation of Glucagon Secretion in Humans.

Cooperberg BA, Cryer PE.

Diabetes Care. 2009 Sep 3. [Epub ahead of print]PMID: 19729529 [PubMed - as supplied by publisher]Related articles

Exercise-related hypoglycemia-associated autonomic failure in diabetes.

Cryer PE.

Diabetes. 2009 Sep;58(9):1951-2. No abstract available. PMID: 19720823 [PubMed - indexed for MEDLINE]Related articles

Attenuated sympathoadrenal responses, but not severe hypoglycemia, during aggressive glycemic therapy of early type 2 diabetes.

Amiel SA, Cryer PE.

Diabetes. 2009 Mar;58(3):515-7. No abstract available. PMID: 19246599 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation and management of adult hypoglycemic disorders: an Endocrine Society Clinical Practice Guideline.

Cryer PE, Axelrod L, Grossman AB, Heller SR, Montori VM, Seaquist ER, Service FJ; Endocrine Society.

J Clin Endocrinol Metab. 2009 Mar;94(3):709-28. Epub 2008 Dec 16.PMID: 19088155 [PubMed - indexed for MEDLINE]Related articles

The barrier of hypoglycemia in diabetes.

Cryer PE.

Diabetes. 2008 Dec;57(12):3169-76. Review. No abstract available. PMID: 19033403 [PubMed - indexed for MEDLINE]Related articlesFree article

Preventing hypoglycaemia: what is the appropriate glucose alert value?

Cryer PE.

Diabetologia. 2009 Jan;52(1):35-7. Epub 2008 Nov 19. No abstract available. PMID: 19018509 [PubMed - indexed for MEDLINE]Related articles

Hypoglycemia: still the limiting factor in the glycemic management of diabetes.

Cryer PE.

Endocr Pract. 2008 Sep;14(6):750-6. Review.PMID: 18996798 [PubMed - indexed for MEDLINE]Related articles

Terbutaline and the prevention of nocturnal hypoglycemia in type 1 diabetes.

Cooperberg BA, Breckenridge SM, Arbelaez AM, Cryer PE.

Diabetes Care. 2008 Dec;31(12):2271-2. Epub 2008 Sep 9.PMID: 18782903 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon and hyperglycaemia in diabetes.

Cryer PE.

Clin Sci (Lond). 2008 May;114(9):589-90.PMID: 18197838 [PubMed - indexed for MEDLINE]Related articles

Attenuation of counterregulatory responses to recurrent hypoglycemia by active thalamic inhibition: a mechanism for hypoglycemia-associated autonomic failure.

Arbelaez AM, Powers WJ, Videen TO, Price JL, Cryer PE.

Diabetes. 2008 Feb;57(2):470-5. Epub 2007 Nov 14.PMID: 18003752 [PubMed - indexed for MEDLINE]Related articlesFree article

Basal insulin, glucagon, and growth hormone replacement.

Breckenridge SM, Raju B, Arbelaez AM, Patterson BW, Cooperberg BA, Cryer PE.

Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1303-10. Epub 2007 Aug 21.PMID: 17711984 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon, in concert with insulin, supports the postabsorptive plasma glucose concentration in humans.

Breckenridge SM, Cooperberg BA, Arbelaez AM, Patterson BW, Cryer PE.

Diabetes. 2007 Oct;56(10):2442-8. Epub 2007 Jul 2.PMID: 17606872 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoglycemia, functional brain failure, and brain death.

Cryer PE.

J Clin Invest. 2007 Apr;117(4):868-70.PMID: 17404614 [PubMed - indexed for MEDLINE]Related articlesFree article

Management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes.

Cryer PE.

Diabetes Care. 2007 Jan;30(1):190-2; author reply 194-6. No abstract available. PMID: 17192371 [PubMed - indexed for MEDLINE]Related articlesFree article

Severe iatrogenic hypoglycemia in type 2 diabetes mellitus.

Cryer PE.

Nat Clin Pract Endocrinol Metab. 2007 Jan;3(1):4-5. No abstract available. PMID: 17179922 [PubMed - indexed for MEDLINE]Related articles

Comment on: Nathan DM, Buse JB, Davidson MB et al (2006) Management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy. A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia 49:1711-1721.

Cryer PE.

Diabetologia. 2007 Jan;50(1):222-4; discussion 225-30; author reply 231-3. Epub 2006 Sep 20. No abstract available. PMID: 17047916 [PubMed - indexed for MEDLINE]Related articles

Hypoglycemia in diabetes: pathophysiological mechanisms and diurnal variation.

Cryer PE.

Prog Brain Res. 2006;153:361-5. Review.PMID: 16876586 [PubMed - indexed for MEDLINE]Related articles

PPARalpha activation elevates blood pressure and does not correct glucocorticoid-induced insulin resistance in humans.

Subramanian S, DeRosa MA, Bernal-Mizrachi C, Laffely N, Cade WT, Yarasheski KE, Cryer PE, Semenkovich CF.

Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1365-71. Epub 2006 Jul 25.PMID: 16868225 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoglycaemia: the limiting factor in the glycaemic management of the critically ill?

Cryer PE.

Diabetologia. 2006 Aug;49(8):1722-5. No abstract available. PMID: 16758178 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of sympathoadrenal failure and hypoglycemia in diabetes.

Cryer PE.

J Clin Invest. 2006 Jun;116(6):1470-3.PMID: 16741570 [PubMed - indexed for MEDLINE]Related articlesFree article

Multiple defects in counterregulation of hypoglycemia in modestly advanced type 2 diabetes mellitus.

Israelian Z, Szoke E, Woerle J, Bokhari S, Schorr M, Schwenke DC, Cryer PE, Gerich JE, Meyer C.

Metabolism. 2006 May;55(5):593-8.PMID: 16631434 [PubMed - indexed for MEDLINE]Related articles

Nocturnal hypoglycemia in type 1 diabetes: an assessment of preventive bedtime treatments.

Raju B, Arbelaez AM, Breckenridge SM, Cryer PE.

J Clin Endocrinol Metab. 2006 Jun;91(6):2087-92. Epub 2006 Feb 21.PMID: 16492699 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of glimepiride and glyburide on glucose counterregulation and recovery from hypoglycemia.

Szoke E, Gosmanov NR, Sinkin JC, Nihalani A, Fender AB, Cryer PE, Meyer C, Gerich JE.

Metabolism. 2006 Jan;55(1):78-83.PMID: 16324923 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of hypoglycemia-associated autonomic failure and its component syndromes in diabetes.

Cryer PE.

Diabetes. 2005 Dec;54(12):3592-601. Review.PMID: 16306382 [PubMed - indexed for MEDLINE]Related articlesFree article

Increasing the decrement in insulin secretion improves glucagon responses to hypoglycemia in advanced type 2 diabetes.

Israelian Z, Gosmanov NR, Szoke E, Schorr M, Bokhari S, Cryer PE, Gerich JE, Meyer C.

Diabetes Care. 2005 Nov;28(11):2691-6.PMID: 16249541 [PubMed - indexed for MEDLINE]Related articlesFree article

Maintenance of the postabsorptive plasma glucose concentration: insulin or insulin plus glucagon?

Raju B, Cryer PE.

Am J Physiol Endocrinol Metab. 2005 Aug;289(2):E181-6. Review.PMID: 16014355 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of the decrement in intraislet insulin for the glucagon response to hypoglycemia in humans.

Gosmanov NR, Szoke E, Israelian Z, Smith T, Cryer PE, Gerich JE, Meyer C.

Diabetes Care. 2005 May;28(5):1124-31.PMID: 15855577 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of the decrement in intraislet insulin plausibly explains loss of the glucagon response to hypoglycemia in insulin-deficient diabetes: documentation of the intraislet insulin hypothesis in humans.

Raju B, Cryer PE.

Diabetes. 2005 Mar;54(3):757-64.PMID: 15734853 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanism, temporal patterns, and magnitudes of the metabolic responses to the KATP channel agonist diazoxide.

Raju B, Cryer PE.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E80-5. Epub 2004 Aug 31.PMID: 15339745 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoglycemia in type 2 diabetes.

Banarer S, Cryer PE.

Med Clin North Am. 2004 Jul;88(4):1107-16, xii-xiii. Review.PMID: 15308392 [PubMed - indexed for MEDLINE]Related articles

Diverse causes of hypoglycemia-associated autonomic failure in diabetes.

Cryer PE.

N Engl J Med. 2004 May 27;350(22):2272-9. Review. No abstract available. PMID: 15163777 [PubMed - indexed for MEDLINE]Related articles

Activation of human medial prefrontal cortex during autonomic responses to hypoglycemia.

Teves D, Videen TO, Cryer PE, Powers WJ.

Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6217-21. Epub 2004 Mar 16.PMID: 15026569 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoglycemia and the sympathoadrenal system: neurogenic symptoms are largely the result of sympathetic neural, rather than adrenomedullary, activation.

DeRosa MA, Cryer PE.

Am J Physiol Endocrinol Metab. 2004 Jul;287(1):E32-41. Epub 2004 Feb 17.PMID: 14970007 [PubMed - indexed for MEDLINE]Related articlesFree article

Cortisol elevations comparable to those that occur during hypoglycemia do not cause hypoglycemia-associated autonomic failure.

Raju B, McGregor VP, Cryer PE.

Diabetes. 2003 Aug;52(8):2083-9.PMID: 12882926 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoglycemia in diabetes.

Cryer PE, Davis SN, Shamoon H.

Diabetes Care. 2003 Jun;26(6):1902-12. Review.PMID: 12766131 [PubMed - indexed for MEDLINE]Related articlesFree article

Renal compensation for impaired hepatic glucose release during hypoglycemia in type 2 diabetes: further evidence for hepatorenal reciprocity.

Woerle HJ, Meyer C, Popa EM, Cryer PE, Gerich JE.

Diabetes. 2003 Jun;52(6):1386-92.PMID: 12765948 [PubMed - indexed for MEDLINE]Related articlesFree article

Sleep-related hypoglycemia-associated autonomic failure in type 1 diabetes: reduced awakening from sleep during hypoglycemia.

Banarer S, Cryer PE.

Diabetes. 2003 May;52(5):1195-203.PMID: 12716752 [PubMed - indexed for MEDLINE]Related articlesFree article

The pathophysiology of hypoglycaemia in diabetes.

Cryer PE.

Diabetes Nutr Metab. 2002 Oct;15(5):330-3; discussion 362. Review. No abstract available. PMID: 12625480 [PubMed - indexed for MEDLINE]Related articles

Hypoglycaemia: the limiting factor in the glycaemic management of Type I and Type II diabetes.

Cryer PE.

Diabetologia. 2002 Jul;45(7):937-48. Epub 2002 Apr 26. Review.PMID: 12136392 [PubMed - indexed for MEDLINE]Related articles

Limited impact of vigorous exercise on defenses against hypoglycemia: relevance to hypoglycemia-associated autonomic failure.

McGregor VP, Greiwe JS, Banarer S, Cryer PE.

Diabetes. 2002 May;51(5):1485-92.PMID: 11978646 [PubMed - indexed for MEDLINE]Related articlesFree article

Intraislet hyperinsulinemia prevents the glucagon response to hypoglycemia despite an intact autonomic response.

Banarer S, McGregor VP, Cryer PE.

Diabetes. 2002 Apr;51(4):958-65.PMID: 11916913 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated endogenous cortisol reduces autonomic neuroendocrine and symptom responses to subsequent hypoglycemia.

McGregor VP, Banarer S, Cryer PE.

Am J Physiol Endocrinol Metab. 2002 Apr;282(4):E770-7.PMID: 11882496 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoglycemia-associated autonomic failure in advanced type 2 diabetes.

Segel SA, Paramore DS, Cryer PE.

Diabetes. 2002 Mar;51(3):724-33.PMID: 11872673 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoglycemia-associated autonomic failure in diabetes.

Cryer PE.

Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1115-21. Review.PMID: 11701423 [PubMed - indexed for MEDLINE]Related articlesFree article

Blood-to-brain glucose transport, cerebral glucose metabolism, and cerebral blood flow are not increased after hypoglycemia.

Segel SA, Fanelli CG, Dence CS, Markham J, Videen TO, Paramore DS, Powers WJ, Cryer PE.

Diabetes. 2001 Aug;50(8):1911-7.PMID: 11473055 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoglycemia risk reduction in type 1 diabetes.

Cryer PE.

Exp Clin Endocrinol Diabetes. 2001;109 Suppl 2:S412-23. Review.PMID: 11460588 [PubMed - indexed for MEDLINE]Related articles

Are gender differences in the responses to hypoglycemia relevant to iatrogenic hypoglycemia in type 1 diabetes?

Cryer PE.

J Clin Endocrinol Metab. 2000 Jun;85(6):2145-7. Review. No abstract available. PMID: 10852443 [PubMed - indexed for MEDLINE]Related articlesFree article

Symptoms of hypoglycemia, thresholds for their occurrence, and hypoglycemia unawareness.

Cryer PE.

Endocrinol Metab Clin North Am. 1999 Sep;28(3):495-500, v-vi. Review.PMID: 10500927 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance in HIV protease inhibitor-associated diabetes.

Yarasheski KE, Tebas P, Sigmund C, Dagogo-Jack S, Bohrer A, Turk J, Halban PA, Cryer PE, Powderly WG.

J Acquir Immune Defic Syndr. 1999 Jul 1;21(3):209-16.PMID: 10421244 [PubMed - indexed for MEDLINE]Related articles

Hypoglycemia is the limiting factor in the management of diabetes.

Cryer PE.

Diabetes Metab Res Rev. 1999 Jan-Feb;15(1):42-6. Review.PMID: 10398545 [PubMed - indexed for MEDLINE]Related articles