PubMed

Enhanced antibody responses to a detoxified lipopolysaccharide-group B meningococcal outer membrane protein vaccine are due to synergistic engagement of Toll-like receptors.

Chen WH, Basu S, Bhattacharjee AK, Cross AS.

Innate Immun. 2009 Oct 12. [Epub ahead of print]PMID: 19822632 [PubMed - as supplied by publisher]Related articles

What is a virulence factor?

Cross AS.

Crit Care. 2008;12(6):196. Epub 2008 Dec 2.PMID: 19090973 [PubMed - indexed for MEDLINE]Related articles

An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.

Li XL, Ezelle HJ, Kang TJ, Zhang L, Shirey KA, Harro J, Hasday JD, Mohapatra SK, Crasta OR, Vogel SN, Cross AS, Hassel BA.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20816-21. Epub 2008 Dec 15.PMID: 19075243 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro and in vivo characterisation of anti-murine IL-13 antibodies recognising distinct functional epitopes.

Berry LM, Adams R, Airey M, Bracher MG, Bourne T, Carrington B, Cross AS, Davies GC, Finney HM, Foulkes R, Gozzard N, Griffin RA, Hailu H, Lamour SD, Lawson AD, Lightwood DJ, McKnight AJ, O'Dowd VL, Oxbrow AK, Popplewell AG, Shaw S, Stephens PE, Sweeney B, Tomlinson KL, Uhe C, Palframan RT.

Int Immunopharmacol. 2009 Feb;9(2):201-6. Epub 2008 Nov 27.PMID: 19041426 [PubMed - indexed for MEDLINE]Related articles

Intranasal administration of a detoxified endotoxin vaccine protects mice against heterologous Gram-negative bacterial pneumonia.

Chen WH, Kang TJ, Bhattacharjee AK, Cross AS.

Innate Immun. 2008 Oct;14(5):269-78.PMID: 18809651 [PubMed - indexed for MEDLINE]Related articles

Differential expression of toll-like receptor genes: sepsis compared with sterile inflammation 1 day before sepsis diagnosis.

Lissauer ME, Johnson SB, Bochicchio GV, Feild CJ, Cross AS, Hasday JD, Whiteford CC, Nussbaumer WA, Towns M, Scalea TM.

Shock. 2009 Mar;31(3):238-44.PMID: 18665047 [PubMed - indexed for MEDLINE]Related articles

Expression of sialyltransferase activity on intact human neutrophils.

Rifat S, Kang TJ, Mann D, Zhang L, Puche AC, Stamatos NM, Goldblum SE, Brossmer R, Cross AS.

J Leukoc Biol. 2008 Oct;84(4):1075-81. Epub 2008 Jul 29.PMID: 18664529 [PubMed - indexed for MEDLINE]Related articlesFree article

Bacillus anthracis spores and lethal toxin induce IL-1beta via functionally distinct signaling pathways.

Kang TJ, Basu S, Zhang L, Thomas KE, Vogel SN, Baillie L, Cross AS.

Eur J Immunol. 2008 Jun;38(6):1574-84.PMID: 18493980 [PubMed - indexed for MEDLINE]Related articles

Macrophage proinflammatory response to Francisella tularensis live vaccine strain requires coordination of multiple signaling pathways.

Cole LE, Santiago A, Barry E, Kang TJ, Shirey KA, Roberts ZJ, Elkins KL, Cross AS, Vogel SN.

J Immunol. 2008 May 15;180(10):6885-91.PMID: 18453609 [PubMed - indexed for MEDLINE]Related articlesFree article

TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia.

Gong P, Angelini DJ, Yang S, Xia G, Cross AS, Mann D, Bannerman DD, Vogel SN, Goldblum SE.

J Biol Chem. 2008 May 9;283(19):13437-49. Epub 2008 Mar 7.PMID: 18326860 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunization with a Pseudomonas aeruginosa 1244 pilin provides O-antigen-specific protection.

Horzempa J, Held TK, Cross AS, Furst D, Qutyan M, Neely AN, Castric P.

Clin Vaccine Immunol. 2008 Apr;15(4):590-7. Epub 2008 Feb 13.PMID: 18272666 [PubMed - indexed for MEDLINE]Related articlesFree article

A case for immunization against nosocomial infections.

Cross AS, Chen WH, Levine MM.

J Leukoc Biol. 2008 Mar;83(3):483-8. Epub 2007 Dec 10. Review.PMID: 18070981 [PubMed - indexed for MEDLINE]Related articlesFree article

From therapy to experimental model: a hundred years of endotoxin administration to human subjects.

Bahador M, Cross AS.

J Endotoxin Res. 2007;13(5):251-79. Review.PMID: 17986486 [PubMed - indexed for MEDLINE]Related articles

Recombinant exosporium protein BclA of Bacillus anthracis is effective as a booster for mice primed with suboptimal amounts of protective antigen.

Brahmbhatt TN, Darnell SC, Carvalho HM, Sanz P, Kang TJ, Bull RL, Rasmussen SB, Cross AS, O'Brien AD.

Infect Immun. 2007 Nov;75(11):5240-7. Epub 2007 Sep 4.PMID: 17785478 [PubMed - indexed for MEDLINE]Related articlesFree article

From rabbits to humans: the contributions of Dr. Theodore E. Woodward to tularemia research.

Cross AS, Calia FM, Edelman R.

Clin Infect Dis. 2007 Jul 15;45 Suppl 1:S61-7.PMID: 17582573 [PubMed - indexed for MEDLINE]Related articles

Protective role of Bacillus anthracis exosporium in macrophage-mediated killing by nitric oxide.

Weaver J, Kang TJ, Raines KW, Cao GL, Hibbs S, Tsai P, Baillie L, Rosen GM, Cross AS.

Infect Immun. 2007 Aug;75(8):3894-901. Epub 2007 May 14.PMID: 17502390 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression profiles differentiate between sterile SIRS and early sepsis.

Johnson SB, Lissauer M, Bochicchio GV, Moore R, Cross AS, Scalea TM.

Ann Surg. 2007 Apr;245(4):611-21.PMID: 17414611 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of Bacillus anthracis spore structures in macrophage cytokine responses.

Basu S, Kang TJ, Chen WH, Fenton MJ, Baillie L, Hibbs S, Cross AS.

Infect Immun. 2007 May;75(5):2351-8. Epub 2007 Mar 5.PMID: 17339355 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for Stat1 in the regulation of lipopolysaccharide-induced interleukin-1beta expression.

Joshi VD, Kalvakolanu DV, Chen W, Zhang L, Kang TJ, Thomas KE, Vogel SN, Cross AS.

J Interferon Cytokine Res. 2006 Oct;26(10):739-47.PMID: 17032168 [PubMed - indexed for MEDLINE]Related articles

Importance of nitric oxide synthase in the control of infection by Bacillus anthracis.

Raines KW, Kang TJ, Hibbs S, Cao GL, Weaver J, Tsai P, Baillie L, Cross AS, Rosen GM.

Infect Immun. 2006 Apr;74(4):2268-76.PMID: 16552057 [PubMed - indexed for MEDLINE]Related articlesFree article

Cutting edge: enhanced pulmonary clearance of Pseudomonas aeruginosa by Muc1 knockout mice.

Lu W, Hisatsune A, Koga T, Kato K, Kuwahara I, Lillehoj EP, Chen W, Cross AS, Gendler SJ, Gewirtz AT, Kim KC.

J Immunol. 2006 Apr 1;176(7):3890-4.PMID: 16547220 [PubMed - indexed for MEDLINE]Related articlesFree article

The use of immunocompromised animals as models for human septic shock.

Opal SM, Cross AS.

Shock. 2005 Dec;24 Suppl 1:64-70.PMID: 16374375 [PubMed - indexed for MEDLINE]Related articles

The use of vaccines in adult patients with renal disease.

Dinits-Pensy M, Forrest GN, Cross AS, Hise MK.

Am J Kidney Dis. 2005 Dec;46(6):997-1011. Review.PMID: 16310566 [PubMed - indexed for MEDLINE]Related articles

Active immunization with a detoxified endotoxin vaccine protects against lethal polymicrobial sepsis: its use with CpG adjuvant and potential mechanisms.

Opal SM, Palardy JE, Chen WH, Parejo NA, Bhattacharjee AK, Cross AS.

J Infect Dis. 2005 Dec 15;192(12):2074-80. Epub 2005 Nov 10.PMID: 16288370 [PubMed - indexed for MEDLINE]Related articles

Murine macrophages kill the vegetative form of Bacillus anthracis.

Kang TJ, Fenton MJ, Weiner MA, Hibbs S, Basu S, Baillie L, Cross AS.

Infect Immun. 2005 Nov;73(11):7495-501.PMID: 16239551 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential expression of endogenous sialidases of human monocytes during cellular differentiation into macrophages.

Stamatos NM, Liang F, Nan X, Landry K, Cross AS, Wang LX, Pshezhetsky AV.

FEBS J. 2005 May;272(10):2545-56.PMID: 15885103 [PubMed - indexed for MEDLINE]Related articlesFree article

Mobilization of neutrophil sialidase activity desialylates the pulmonary vascular endothelial surface and increases resting neutrophil adhesion to and migration across the endothelium.

Sakarya S, Rifat S, Zhou J, Bannerman DD, Stamatos NM, Cross AS, Goldblum SE.

Glycobiology. 2004 Jun;14(6):481-94. Epub 2004 Mar 24.PMID: 15044387 [PubMed - indexed for MEDLINE]Related articlesFree article

O antigen seroepidemiology of Klebsiella clinical isolates and implications for immunoprophylaxis of Klebsiella infections.

Trautmann M, Held TK, Cross AS.

Vaccine. 2004 Feb 17;22(7):818-21.PMID: 15040933 [PubMed - indexed for MEDLINE]Related articles

Development of an anti-core lipopolysaccharide vaccine for the prevention and treatment of sepsis.

Cross AS, Opal S, Cook P, Drabick J, Bhattacharjee A.

Vaccine. 2004 Feb 17;22(7):812-7. Review.PMID: 15040932 [PubMed - indexed for MEDLINE]Related articles

Meeting summary: possibilities for active and passive vaccination against opportunistic infections.

Walker RI, Blanchard T, Braun JM, Cebra JJ, Cross AS, Fattom A, Giannasca PJ, Holder IA, Huebner J, Matthews R, Pier GB, Romani L, von Specht BU, Trautmann M.

Vaccine. 2004 Feb 17;22(7):801-4. No abstract available. PMID: 15040930 [PubMed - indexed for MEDLINE]Related articles

Simultaneous activation of apoptosis and inflammation in pathogenesis of septic shock: a hypothesis.

Joshi VD, Kalvakolanu DV, Cross AS.

FEBS Lett. 2003 Dec 4;555(2):180-4.PMID: 14644412 [PubMed - indexed for MEDLINE]Related articles

Desialylation of glycoconjugates on the surface of monocytes activates the extracellular signal-related kinases ERK 1/2 and results in enhanced production of specific cytokines.

Stamatos NM, Curreli S, Zella D, Cross AS.

J Leukoc Biol. 2004 Feb;75(2):307-13. Epub 2003 Nov 21.PMID: 14634064 [PubMed - indexed for MEDLINE]Related articlesFree article

Phase I study of detoxified Escherichia coli J5 lipopolysaccharide (J5dLPS)/group B meningococcal outer membrane protein (OMP) complex vaccine in human subjects.

Cross AS, Opal SM, Palardy JE, Drabick JJ, Warren HS, Huber C, Cook P, Bhattacharjee AK.

Vaccine. 2003 Nov 7;21(31):4576-87.PMID: 14575770 [PubMed - indexed for MEDLINE]Related articles

A new paradigm for the treatment of sepsis: is it time to consider combination therapy?

Cross AS, Opal SM.

Ann Intern Med. 2003 Mar 18;138(6):502-5. Review.PMID: 12639085 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein tyrosine phosphatase activity regulates endothelial cell-cell interactions, the paracellular pathway, and capillary tube stability.

Young BA, Sui X, Kiser TD, Hyun SW, Wang P, Sakarya S, Angelini DJ, Schaphorst KL, Hasday JD, Cross AS, Romer LH, Passaniti A, Goldblum SE.

Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L63-75. Epub 2003 Mar 7.PMID: 12626337 [PubMed - indexed for MEDLINE]Related articlesFree article

Recruitment of murine neutrophils in vivo through endogenous sialidase activity.

Cross AS, Sakarya S, Rifat S, Held TK, Drysdale BE, Grange PA, Cassels FJ, Wang LX, Stamatos N, Farese A, Casey D, Powell J, Bhattacharjee AK, Kleinberg M, Goldblum SE.

J Biol Chem. 2003 Feb 7;278(6):4112-20. Epub 2002 Nov 22.PMID: 12446694 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of caspase 1 in murine antibacterial host defenses and lethal endotoxemia.

Joshi VD, Kalvakolanu DV, Hebel JR, Hasday JD, Cross AS.

Infect Immun. 2002 Dec;70(12):6896-903.PMID: 12438367 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of two different routes of immunization on protection against gram-negative sepsis by a detoxified Escherichia coli J5 lipopolysaccharide group B meningococcal outer membrane protein complex vaccine in a burned mouse model.

Neely AN, Bhattacharjee AK, Babcock GF, Holder IA, Cross AS.

J Burn Care Rehabil. 2002 Sep-Oct;23(5):333-40.PMID: 12352135 [PubMed - indexed for MEDLINE]Related articles

IL-18 levels and the outcome of innate immune response to lipopolysaccharide: importance of a positive feedback loop with caspase-1 in IL-18 expression.

Joshi VD, Kalvakolanu DV, Hasday JD, Hebel RJ, Cross AS.

J Immunol. 2002 Sep 1;169(5):2536-44.PMID: 12193723 [PubMed - indexed for MEDLINE]Related articlesFree article

Endotoxin tolerance-current concepts in historical perspective.

Cross AS.

J Endotoxin Res. 2002;8(2):83-98. Review. No abstract available. PMID: 12028748 [PubMed - indexed for MEDLINE]Related articles

Endotoxin stress-response in cardiomyocytes: NF-kappaB activation and tumor necrosis factor-alpha expression.

Wright G, Singh IS, Hasday JD, Farrance IK, Hall G, Cross AS, Rogers TB.

Am J Physiol Heart Circ Physiol. 2002 Mar;282(3):H872-9.PMID: 11834481 [PubMed - indexed for MEDLINE]Related articlesFree article

IFN-gamma inhibits lipopolysaccharide-induced interleukin-1 beta in primary murine macrophages via a Stat1-dependent pathway.

De Boer ML, Hu J, Kalvakolanu DV, Hasday JD, Cross AS.

J Interferon Cytokine Res. 2001 Jul;21(7):485-94.PMID: 11506742 [PubMed - indexed for MEDLINE]Related articles

Unusual persistence in healthy volunteers and ill patients of hyperimmune immunoglobulin directed against multiple Pseudomonas O-chain and Klebsiella serotypes after intravenous infusion.

McClain JB, Edelman R, Shmuklarsky M, Que J, Cryz SJ, Cross AS.

Vaccine. 2001 May 14;19(25-26):3499-508.PMID: 11348717 [PubMed - indexed for MEDLINE]Related articles

Active immunization with a detoxified Escherichia coli J5 lipopolysaccharide group B meningococcal outer membrane protein complex vaccine protects animals from experimental sepsis.

Cross AS, Opal SM, Warren HS, Palardy JE, Glaser K, Parejo NA, Bhattacharjee AK.

J Infect Dis. 2001 Apr 1;183(7):1079-86. Epub 2001 Mar 8.PMID: 11237833 [PubMed - indexed for MEDLINE]Related articles

Exposure to febrile temperature modifies endothelial cell response to tumor necrosis factor-alpha.

Hasday JD, Bannerman D, Sakarya S, Cross AS, Singh IS, Howard D, Drysdale BE, Goldblum SE.

J Appl Physiol. 2001 Jan;90(1):90-8.PMID: 11133897 [PubMed - indexed for MEDLINE]Related articlesFree article

Kinetics of cellular and cytokine responses in a chimeric mouse model for the study of staphylococcal enterotoxin B pathogenesis.

Yuan L, Lowell GH, Hoover DL, Colleton CA, Hammack CA Sr, Young LD, Fischer R, Patchen ML, Cross AS.

Immunol Lett. 2000 Jan 10;71(1):19-26.PMID: 10709781 [PubMed - indexed for MEDLINE]Related articles

Febrile core temperature is essential for optimal host defense in bacterial peritonitis.

Jiang Q, Cross AS, Singh IS, Chen TT, Viscardi RM, Hasday JD.

Infect Immun. 2000 Mar;68(3):1265-70.PMID: 10678936 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunotherapy of sepsis: flawed concept or faulty implementation?

Cross AS, Opal SM, Bhattacharjee AK, Donta ST, Peduzzi PN, Fürer E, Que JU, Cryz SJ.

Vaccine. 1999 Oct 1;17 Suppl 2:S13-21. Review.PMID: 10506404 [PubMed - indexed for MEDLINE]Related articles

Exposure to febrile temperature upregulates expression of pyrogenic cytokines in endotoxin-challenged mice.

Jiang Q, Detolla L, Singh IS, Gatdula L, Fitzgerald B, van Rooijen N, Cross AS, Hasday JD.

Am J Physiol. 1999 Jun;276(6 Pt 2):R1653-60.PMID: 10362744 [PubMed - indexed for MEDLINE]Related articlesFree article

Vaccines and antibodies in the prevention and treatment of sepsis.

Bhattacharjee AK, Cross AS.

Infect Dis Clin North Am. 1999 Jun;13(2):355-69, vii. Review.PMID: 10340171 [PubMed - indexed for MEDLINE]Related articles