PubMed

Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo.

Fiaschi-Taesch N, Bigatel TA, Sicari B, Takane KK, Salim F, Velazquez-Garcia S, Harb G, Selk K, Cozar-Castellano I, Stewart AF.

Diabetes. 2009 Apr;58(4):882-93. Epub 2009 Jan 9.PMID: 19136653 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutant parathyroid hormone-related protein, devoid of the nuclear localization signal, markedly inhibits arterial smooth muscle cell cycle and neointima formation by coordinate up-regulation of p15Ink4b and p27kip1.

Fiaschi-Taesch N, Sicari B, Ubriani K, Cozar-Castellano I, Takane KK, Stewart AF.

Endocrinology. 2009 Mar;150(3):1429-39. Epub 2008 Oct 9.PMID: 18845646 [PubMed - indexed for MEDLINE]Related articles

Lessons from the first comprehensive molecular characterization of cell cycle control in rodent insulinoma cell lines.

Cozar-Castellano I, Harb G, Selk K, Takane K, Vasavada R, Sicari B, Law B, Zhang P, Scott DK, Fiaschi-Taesch N, Stewart AF.

Diabetes. 2008 Nov;57(11):3056-68. Epub 2008 Jul 23.PMID: 18650366 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific deletion of the retinoblastoma protein in the pancreatic beta-cell has limited effects on beta-cell replication, mass, and function.

Vasavada RC, Cozar-Castellano I, Sipula D, Stewart AF.

Diabetes. 2007 Jan;56(1):57-64.PMID: 17192465 [PubMed - indexed for MEDLINE]Related articlesFree article

The cell cycle inhibitory protein p21cip is not essential for maintaining beta-cell cycle arrest or beta-cell function in vivo.

Cozar-Castellano I, Haught M, Stewart AF.

Diabetes. 2006 Dec;55(12):3271-8.PMID: 17130470 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular mechanism through which parathyroid hormone-related protein induces proliferation in arterial smooth muscle cells: definition of an arterial smooth muscle PTHrP/p27kip1 pathway.

Fiaschi-Taesch N, Sicari BM, Ubriani K, Bigatel T, Takane KK, Cozar-Castellano I, Bisello A, Law B, Stewart AF.

Circ Res. 2006 Oct 27;99(9):933-42. Epub 2006 Oct 5.PMID: 17023675 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular control of cell cycle progression in the pancreatic beta-cell.

Cozar-Castellano I, Fiaschi-Taesch N, Bigatel TA, Takane KK, Garcia-Ocaña A, Vasavada R, Stewart AF.

Endocr Rev. 2006 Jun;27(4):356-70. Epub 2006 Apr 25. Review.PMID: 16638909 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of beta-cell replication in mice transgenic for hepatocyte growth factor and placental lactogen: comprehensive characterization of the G1/S regulatory proteins reveals unique involvement of p21cip.

Cozar-Castellano I, Weinstock M, Haught M, Velázquez-Garcia S, Sipula D, Stewart AF.

Diabetes. 2006 Jan;55(1):70-7.PMID: 16380478 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth factors and beta cell replication.

Vasavada RC, Gonzalez-Pertusa JA, Fujinaka Y, Fiaschi-Taesch N, Cozar-Castellano I, Garcia-Ocaña A.

Int J Biochem Cell Biol. 2006;38(5-6):931-50. Epub 2005 Aug 31. Review.PMID: 16168703 [PubMed - indexed for MEDLINE]Related articles

Molecular engineering human hepatocytes into pancreatic beta cells for diabetes therapy.

Cozar-Castellano I, Stewart AF.

Proc Natl Acad Sci U S A. 2005 May 31;102(22):7781-2. Epub 2005 May 23. No abstract available. PMID: 15911749 [PubMed - indexed for MEDLINE]Related articlesFree article

hIscA: a protein implicated in the biogenesis of iron-sulfur clusters.

Cózar-Castellano I, del Valle Machargo M, Trujillo E, Arteaga MF, González T, Martín-Vasallo P, Avila J.

Biochim Biophys Acta. 2004 Aug 2;1700(2):179-88.PMID: 15262227 [PubMed - indexed for MEDLINE]Related articles

Hepatocyte growth factor gene therapy for islet transplantation.

Rao P, Cozar-Castellano I, Roccisana J, Vasavada RC, Garcia-Ocaña A.

Expert Opin Biol Ther. 2004 Apr;4(4):507-18. Review.PMID: 15102600 [PubMed - indexed for MEDLINE]Related articles

Induction of beta-cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclin-dependent kinase-4 and cyclin D1.

Cozar-Castellano I, Takane KK, Bottino R, Balamurugan AN, Stewart AF.

Diabetes. 2004 Jan;53(1):149-59.PMID: 14693709 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression and cellular localization of Na,K-ATPase isoforms in the rat ventral prostate.

Mobasheri A, Pestov NB, Papanicolaou S, Kajee R, Cózar-Castellano I, Avila J, Martín-Vasallo P, Foster CS, Modyanov NN, Djamgoz MB.

BJU Int. 2003 Nov;92(7):793-802.PMID: 14616469 [PubMed - indexed for MEDLINE]Related articles

Hepatocyte growth factor gene therapy for pancreatic islets in diabetes: reducing the minimal islet transplant mass required in a glucocorticoid-free rat model of allogeneic portal vein islet transplantation.

Lopez-Talavera JC, Garcia-Ocaña A, Sipula I, Takane KK, Cozar-Castellano I, Stewart AF.

Endocrinology. 2004 Feb;145(2):467-74. Epub 2003 Oct 9.PMID: 14551233 [PubMed - indexed for MEDLINE]Related articlesFree article

Na+, K+-ATPase isozyme diversity; comparative biochemistry and physiological implications of novel functional interactions.

Mobasheri A, Avila J, Cózar-Castellano I, Brownleader MD, Trevan M, Francis MJ, Lamb JF, Martín-Vasallo P.

Biosci Rep. 2000 Apr;20(2):51-91. Review.PMID: 10965965 [PubMed - indexed for MEDLINE]Related articles