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    Results: 1 to 50 of 102

    1.

    A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene.

    Church C, Lee S, Bagg EA, McTaggart JS, Deacon R, Gerken T, Lee A, Moir L, Mecinović J, Quwailid MM, Schofield CJ, Ashcroft FM, Cox RD.

    PLoS Genet. 2009 Aug;5(8):e1000599. Epub 2009 Aug 14.PMID: 19680540 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Functional annotations of diabetes nephropathy susceptibility loci through analysis of genome-wide renal gene expression in rat models of diabetes mellitus.

    Hu Y, Kaisaki PJ, Argoud K, Wilder SP, Wallace KJ, Woon PY, Blancher C, Tarnow L, Groop PH, Hadjadj S, Marre M, Parving HH, Farrall M, Cox RD, Lathrop M, Vionnet N, Bihoreau MT, Gauguier D.

    BMC Med Genomics. 2009 Jul 9;2:41.PMID: 19586551 [PubMed - in process]Related articlesFree article

    3.

    Insulin secretion from beta-cells is affected by deletion of nicotinamide nucleotide transhydrogenase.

    Shimomura K, Galvanovskis J, Goldsworthy M, Hugill A, Kaizak S, Lee A, Meadows N, Quwailid MM, Rydström J, Teboul L, Ashcroft F, Cox RD.

    Methods Enzymol. 2009;457:451-80.PMID: 19426883 [PubMed - indexed for MEDLINE]Related articles

    4.

    A missense mutation in the non-neural G-protein alpha-subunit isoforms modulates susceptibility to obesity.

    Kelly ML, Moir L, Jones L, Whitehill E, Anstee QM, Goldin RD, Hough A, Cheeseman M, Jansson JO, Peters J, Cox RD.

    Int J Obes (Lond). 2009 May;33(5):507-18. Epub 2009 Feb 24.PMID: 19238158 [PubMed - in process]Related articles

    5.

    ENU mutagenesis, a way forward to understand gene function.

    Acevedo-Arozena A, Wells S, Potter P, Kelly M, Cox RD, Brown SD.

    Annu Rev Genomics Hum Genet. 2008;9:49-69. Review.PMID: 18949851 [PubMed - indexed for MEDLINE]Related articles

    6.

    Phenotyping murine models of non-alcoholic fatty liver disease through metabolic profiling of intact liver tissue.

    Cobbold JF, Anstee QM, Goldin RD, Williams HR, Matthews HC, North BV, Absalom N, Thomas HC, Thursz MR, Cox RD, Taylor-Robinson SD, Cox IJ.

    Clin Sci (Lond). 2009 Mar;116(5):403-13.PMID: 18694396 [PubMed - indexed for MEDLINE]Related articles

    7.

    Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance.

    Goldsworthy M, Hugill A, Freeman H, Horner E, Shimomura K, Bogani D, Pieles G, Mijat V, Arkell R, Bhattacharya S, Ashcroft FM, Cox RD.

    Diabetes. 2008 Aug;57(8):2234-44. Epub 2008 May 13.PMID: 18477811 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    A kinetic core model of the glucose-stimulated insulin secretion network of pancreatic beta cells.

    Jiang N, Cox RD, Hancock JM.

    Mamm Genome. 2007 Jul;18(6-7):508-20. Epub 2007 May 21.PMID: 17514510 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human.

    Salek RM, Maguire ML, Bentley E, Rubtsov DV, Hough T, Cheeseman M, Nunez D, Sweatman BC, Haselden JN, Cox RD, Connor SC, Griffin JL.

    Physiol Genomics. 2007 Apr 24;29(2):99-108. Epub 2006 Dec 26.PMID: 17190852 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Nicotinamide nucleotide transhydrogenase: a link between insulin secretion, glucose metabolism and oxidative stress.

    Freeman H, Shimomura K, Cox RD, Ashcroft FM.

    Biochem Soc Trans. 2006 Nov;34(Pt 5):806-10.PMID: 17052203 [PubMed - indexed for MEDLINE]Related articles

    11.

    Type-2 diabetes: a cocktail of genetic discovery.

    Freeman H, Cox RD.

    Hum Mol Genet. 2006 Oct 15;15 Spec No 2:R202-9. Review.PMID: 16987885 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Deletion of nicotinamide nucleotide transhydrogenase: a new quantitive trait locus accounting for glucose intolerance in C57BL/6J mice.

    Freeman HC, Hugill A, Dear NT, Ashcroft FM, Cox RD.

    Diabetes. 2006 Jul;55(7):2153-6.PMID: 16804088 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion.

    Freeman H, Shimomura K, Horner E, Cox RD, Ashcroft FM.

    Cell Metab. 2006 Jan;3(1):35-45.PMID: 16399503 [PubMed - indexed for MEDLINE]Related articles

    14.

    Evaluation of potential adverse health effects resulting from chronic domestic exposure to the organophosphate insecticide methyl parathion.

    Cox RD, Kolb JC, Galli RL, Carlton FR, Cook AM.

    Clin Toxicol (Phila). 2005;43(4):243-53.PMID: 16035200 [PubMed - indexed for MEDLINE]Related articles

    15.

    The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

    Willnow T, Antignac C, Brändli A, Christensen E, Cox R, Davidson D, Davies J, Devuyst O, Eichele G, Hastie N, Verroust P, Schedl A, Meij I.

    Organogenesis. 2005 Apr;2(2):42-7.PMID: 19521566 [PubMed - in process]Related articlesFree article

    16.

    A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice.

    Toye AA, Lippiat JD, Proks P, Shimomura K, Bentley L, Hugill A, Mijat V, Goldsworthy M, Moir L, Haynes A, Quarterman J, Freeman HC, Ashcroft FM, Cox RD.

    Diabetologia. 2005 Apr;48(4):675-86. Epub 2005 Feb 24.PMID: 15729571 [PubMed - indexed for MEDLINE]Related articles

    17.

    SNP haplotypes in the angiotensin I-converting enzyme (ACE) gene: analysis of Nigerian family data using gamete competition models.

    McKenzie CA, Sinsheimer JS, Adeyemo AA, Cox RD, Southam L, Hugill A, Bouzekri N, Lathrop M, Forrester TE, Cooper RS, Ward R.

    Ann Hum Genet. 2005 Mar;69(Pt 2):227-32.PMID: 15720304 [PubMed - indexed for MEDLINE]Related articles

    18.

    The Collaborative Cross, a community resource for the genetic analysis of complex traits.

    Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, Burmeister M, Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD, Crabbe JC, Crusio WE, Darvasi A, Deschepper CF, Doerge RW, Farber CR, Forejt J, Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G, Hayes NL, Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA, Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE, Kempermann G, Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F, Lassalle JM, Lowenstein PR, Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR, Mittleman G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH, Nagase H, Nowakowski RS, O'Hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K, Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M, Prows DR, Qi Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC, Seltzer Z, Shimomura K, Shou S, Sillanpää MJ, Siracusa LD, Snoeck HW, Spearow JL, Svenson K, Tarantino LM, Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams RW, Wiltshire T, Yi N, Zhang D, Zhang M, Zou F; Complex Trait Consortium.

    Nat Genet. 2004 Nov;36(11):1133-7.PMID: 15514660 [PubMed - indexed for MEDLINE]Related articles

    19.

    A gene-driven ENU-based approach to generating an allelic series in any gene.

    Quwailid MM, Hugill A, Dear N, Vizor L, Wells S, Horner E, Fuller S, Weedon J, McMath H, Woodman P, Edwards D, Campbell D, Rodger S, Carey J, Roberts A, Glenister P, Lalanne Z, Parkinson N, Coghill EL, McKeone R, Cox S, Willan J, Greenfield A, Keays D, Brady S, Spurr N, Gray I, Hunter J, Brown SD, Cox RD.

    Mamm Genome. 2004 Aug;15(8):585-91.PMID: 15457338 [PubMed - indexed for MEDLINE]Related articles

    20.

    New semidominant mutations that affect mouse development.

    Bogani D, Warr N, Elms P, Davies J, Tymowska-Lalanne Z, Goldsworthy M, Cox RD, Keays DA, Flint J, Wilson V, Nolan P, Arkell R.

    Genesis. 2004 Oct;40(2):109-117.PMID: 15384171 [PubMed - indexed for MEDLINE]Related articles

    21.

    Ethylene glycol toxicity.

    Cox RD, Phillips WJ.

    Mil Med. 2004 Aug;169(8):660-3.PMID: 15379080 [PubMed - indexed for MEDLINE]Related articles

    22.

    Chromosomal mapping of genetic loci controlling absence epilepsy phenotypes in the WAG/Rij rat.

    Gauguier D, van Luijtelaar G, Bihoreau MT, Wilder SP, Godfrey RF, Vossen J, Coenen A, Cox RD.

    Epilepsia. 2004 Aug;45(8):908-15.PMID: 15270755 [PubMed - indexed for MEDLINE]Related articles

    23.

    ENU mutagenesis in the mouse: application to human genetic disease.

    Nolan PM, Hugill A, Cox RD.

    Brief Funct Genomic Proteomic. 2002 Oct;1(3):278-89. Review.PMID: 15239894 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    A comparative analysis of phenothiazinium salts for the photosensitisation of murine fibrosarcoma (RIF-1) cells in vitro.

    Walker I, Gorman SA, Cox RD, Vernon DI, Griffiths J, Brown SB.

    Photochem Photobiol Sci. 2004 Jul;3(7):653-9. Epub 2004 Apr 29.PMID: 15239000 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    A new mouse model of type 2 diabetes, produced by N-ethyl-nitrosourea mutagenesis, is the result of a missense mutation in the glucokinase gene.

    Toye AA, Moir L, Hugill A, Bentley L, Quarterman J, Mijat V, Hough T, Goldsworthy M, Haynes A, Hunter AJ, Browne M, Spurr N, Cox RD.

    Diabetes. 2004 Jun;53(6):1577-83.PMID: 15161764 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    Acute upper-airway obstruction in a two-year-old child who ingested an herbicide preparation.

    Bradley KG, Cox RD.

    J Miss State Med Assoc. 2004 Apr;45(4):98-101. No abstract available. PMID: 15114794 [PubMed - indexed for MEDLINE]Related articles

    27.

    Association between droperidol use and sudden death in two patients intoxicated with illicit stimulant drugs.

    Cox RD, Koelliker DE, Bradley KG.

    Vet Hum Toxicol. 2004 Feb;46(1):21-3.PMID: 14748411 [PubMed - indexed for MEDLINE]Related articles

    28.

    Rodent models of genetic disease.

    Cox RD, Brown SD.

    Curr Opin Genet Dev. 2003 Jun;13(3):278-83. Review.PMID: 12787790 [PubMed - indexed for MEDLINE]Related articles

    29.

    Novel phenotypes identified by plasma biochemical screening in the mouse.

    Hough TA, Nolan PM, Tsipouri V, Toye AA, Gray IC, Goldsworthy M, Moir L, Cox RD, Clements S, Glenister PH, Wood J, Selley RL, Strivens MA, Vizor L, McCormack SL, Peters J, Fisher EM, Spurr N, Rastan S, Martin JE, Brown SD, Hunter AJ.

    Mamm Genome. 2002 Oct;13(10):595-602.PMID: 12420138 [PubMed - indexed for MEDLINE]Related articles

    30.

    Blunt trauma in the obstetric patient: monitoring practices in the ED.

    Kolb JC, Carlton FB, Cox RD, Summers RL.

    Am J Emerg Med. 2002 Oct;20(6):524-7.PMID: 12369026 [PubMed - indexed for MEDLINE]Related articles

    31.

    In vitro photodynamic activity of a series of methylene blue analogues.

    Mellish KJ, Cox RD, Vernon DI, Griffiths J, Brown SB.

    Photochem Photobiol. 2002 Apr;75(4):392-7.PMID: 12003129 [PubMed - indexed for MEDLINE]Related articles

    32.

    Injuries sustained during competitive white-water paddling: a survey of athletes in the 1996 Olympic trials.

    Krupnick JE, Cox RD, Summers RL.

    Wilderness Environ Med. 1998;9(1):14-8.PMID: 11990175 [PubMed - indexed for MEDLINE]Related articles

    33.

    A gene-driven approach to the identification of ENU mutants in the mouse.

    Coghill EL, Hugill A, Parkinson N, Davison C, Glenister P, Clements S, Hunter J, Cox RD, Brown SD.

    Nat Genet. 2002 Mar;30(3):255-6. Epub 2002 Feb 19.PMID: 11850622 [PubMed - indexed for MEDLINE]Related articles

    34.

    A radiation hybrid transcript map of the mouse genome.

    Avner P, Bruls T, Poras I, Eley L, Gas S, Ruiz P, Wiles MV, Sousa-Nunes R, Kettleborough R, Rana A, Morissette J, Bentley L, Goldsworthy M, Haynes A, Herbert E, Southam L, Lehrach H, Weissenbach J, Manenti G, Rodriguez-Tome P, Beddington R, Dunwoodie S, Cox RD.

    Nat Genet. 2001 Oct;29(2):194-200.PMID: 11586301 [PubMed - indexed for MEDLINE]Related articles

    35.

    Comparison of fluorescent single-strand conformation polymorphism analysis and denaturing high-performance liquid chromatography for detection of EXT1 and EXT2 mutations in hereditary multiple exostoses.

    Dobson-Stone C, Cox RD, Lonie L, Southam L, Fraser M, Wise C, Bernier F, Hodgson S, Porter DE, Simpson AH, Monaco AP.

    Eur J Hum Genet. 2000 Jan;8(1):24-32.PMID: 10713884 [PubMed - indexed for MEDLINE]Related articlesFree article

    36.

    Studies of the lethargic (lh/lh) mouse model of absence seizures: regulatory mechanisms and identification of the lh gene.

    Hosford DA, Lin FH, Wang Y, Caddick SJ, Rees M, Parkinson NJ, Barclay J, Cox RD, Gardiner RM, Hosford DA, Denton P, Wang Y, Seldin MF, Chen B.

    Adv Neurol. 1999;79:239-52. Review.PMID: 10514818 [PubMed - indexed for MEDLINE]Related articles

    37.

    Refined linkage disequilibrium and physical mapping of the gene locus for X-linked dystonia-parkinsonism (DYT3).

    Németh AH, Nolte D, Dunne E, Niemann S, Kostrzewa M, Peters U, Fraser E, Bochukova E, Butler R, Brown J, Cox RD, Levy ER, Ropers HH, Monaco AP, Müller U.

    Genomics. 1999 Sep 15;60(3):320-9.PMID: 10493831 [PubMed - indexed for MEDLINE]Related articles

    38.

    Evolution of a filmless digital imaging and communications in medicine-conformant picture archiving and communications system: design issues and lessons learned over the last 3 years.

    Henri CJ, Cox RD, Rubin R, Bret PM, Couch GG.

    J Digit Imaging. 1999 May;12(2 Suppl 1):178-80.PMID: 10342204 [PubMed - indexed for MEDLINE]Related articles

    39.

    Transparent image access in a distributed picture archiving and communications system: the Master Database broker.

    Cox RD, Henri CJ, Rubin RK.

    J Digit Imaging. 1999 May;12(2 Suppl 1):175-7.PMID: 10342203 [PubMed - indexed for MEDLINE]Related articles

    41.

    Contrasting effects of ENU induced embryonic lethal mutations of the quaking gene.

    Cox RD, Hugill A, Shedlovsky A, Noveroske JK, Best S, Justice MJ, Lehrach H, Dove WF.

    Genomics. 1999 May 1;57(3):333-41.PMID: 10328999 [PubMed - indexed for MEDLINE]Related articles

    42.

    UKPDS 31: Hepatocyte nuclear factor-1alpha (the MODY3 gene) mutations in late onset Type II diabetic patients in the United Kingdom. United Kingdom prospective diabetes study.

    Cox RD, Southam L, Hashim Y, Horton V, Mehta Z, Taghavi J, Lathrop M, Turner R.

    Diabetologia. 1999 Jan;42(1):120-1. No abstract available. PMID: 10027593 [PubMed - indexed for MEDLINE]Related articles

    43.

    Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family.

    Brown SD, Twells RC, Hey PJ, Cox RD, Levy ER, Soderman AR, Metzker ML, Caskey CT, Todd JA, Hess JF.

    Biochem Biophys Res Commun. 1998 Jul 30;248(3):879-88.PMID: 9704021 [PubMed - indexed for MEDLINE]Related articles

    44.

    Fine mapping of the diabetes-susceptibility locus, IDDM4, on chromosome 11q13.

    Nakagawa Y, Kawaguchi Y, Twells RC, Muxworthy C, Hunter KM, Wilson A, Merriman ME, Cox RD, Merriman T, Cucca F, McKinney PA, Shield JP, Tuomilehto J, Tuomilehto-Wolf E, Ionesco-Tirgoviste C, Nisticò L, Buzzetti R, Pozzilli P, Joner G, Thorsby E, Undlien DE, Pociot F, Nerup J, Rönningen KS, Bain SC, Todd JA; Bart's-Oxford Family Study Group.

    Am J Hum Genet. 1998 Aug;63(2):547-56.PMID: 9683605 [PubMed - indexed for MEDLINE]Related articlesFree article

    45.

    Transmission of haplotypes of microsatellite markers rather than single marker alleles in the mapping of a putative type 1 diabetes susceptibility gene (IDDM6).

    Merriman TR, Eaves IA, Twells RC, Merriman ME, Danoy PA, Muxworthy CE, Hunter KM, Cox RD, Cucca F, McKinney PA, Shield JP, Baum JD, Tuomilehto J, Tuomilehto-Wolf E, Ionesco-Tirgoviste C, Joner G, Thorsby E, Undlien DE, Pociot F, Nerup J, Ronningen KS, Bain SC, Todd JA.

    Hum Mol Genet. 1998 Mar;7(3):517-24.PMID: 9467012 [PubMed - indexed for MEDLINE]Related articlesFree article

    46.

    CD-based image archival and management on a hybrid radiology intranet.

    Cox RD, Henri CJ, Bret PM.

    J Digit Imaging. 1997 Aug;10(3 Suppl 1):168-70.PMID: 9268870 [PubMed - indexed for MEDLINE]Related articles

    47.

    Implementation of a filmless mini picture archiving and communication system in ultrasonography: experience after one year of use.

    Henri CJ, Cox RD, Bret PM.

    J Digit Imaging. 1997 Aug;10(3 Suppl 1):80-2.PMID: 9268846 [PubMed - indexed for MEDLINE]Related articles

    48.

    Design and implementation of World Wide Web-based tools for image management in computed tomography, magnetic resonance imaging, and ultrasonography.

    Henri CJ, Rubin RK, Cox RD, Bret PM.

    J Digit Imaging. 1997 Aug;10(3 Suppl 1):77-9.PMID: 9268845 [PubMed - indexed for MEDLINE]Related articles

    49.

    Identification of nine novel mutations in the hepatocyte nuclear factor 1 alpha gene associated with maturity-onset diabetes of the young (MODY3).

    Vaxillaire M, Rouard M, Yamagata K, Oda N, Kaisaki PJ, Boriraj VV, Chevre JC, Boccio V, Cox RD, Lathrop GM, Dussoix P, Philippe J, Timsit J, Charpentier G, Velho G, Bell GI, Froguel P.

    Hum Mol Genet. 1997 Apr;6(4):583-6.PMID: 9097962 [PubMed - indexed for MEDLINE]Related articlesFree article

    50.

    Identification of polygenic disease genes.

    Cox RD.

    J Rheumatol. 1997 Jan;24(1):202-5.PMID: 9002039 [PubMed - indexed for MEDLINE]Related articles

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