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The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis.
Guo S, Copps KD, Dong X, Park S, Cheng Z, Pocai A, Rossetti L, Sajan M, Farese RV, White MF.
Mol Cell Biol. 2009 Sep;29(18):5070-83. Epub 2009 Jul 13.PMID: 19596788 [PubMed - indexed for MEDLINE]Related articles
Breathing room: the (un)natural history of adipose microhypoxia and insulin resistance.
Copps KD, White MF.
Diabetes. 2009 Jan;58(1):26-7. No abstract available. PMID: 19114728 [PubMed - indexed for MEDLINE]Related articlesFree article
Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation.
Dong XC, Copps KD, Guo S, Li Y, Kollipara R, DePinho RA, White MF.
Cell Metab. 2008 Jul;8(1):65-76.PMID: 18590693 [PubMed - indexed for MEDLINE]Related articles
Phosphorylation of Irs1 at SER-522 inhibits insulin signaling.
Giraud J, Haas M, Feener EP, Copps KD, Dong X, Dunn SL, White MF.
Mol Endocrinol. 2007 Sep;21(9):2294-302. Epub 2007 Jun 19.PMID: 17579213 [PubMed - indexed for MEDLINE]Related articlesFree article
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