PubMed

Evidence that multiple genetic variants of MC4R play a functional role in the regulation of energy expenditure and appetite in Hispanic children.

Cole SA, Butte NF, Voruganti VS, Cai G, Haack K, Kent JW Jr, Blangero J, Comuzzie AG, McPherson JD, Gibbs RA.

Am J Clin Nutr. 2009 Nov 4. [Epub ahead of print]PMID: 19889825 [PubMed - as supplied by publisher]Related articles

Genetic variation in PARL influences mitochondrial content.

Curran JE, Jowett JB, Abraham LJ, Diepeveen LA, Elliott KS, Dyer TD, Kerr-Bayles LJ, Johnson MP, Comuzzie AG, Moses EK, Walder KR, Collier GR, Blangero J, Kissebah AH.

Hum Genet. 2009 Oct 28. [Epub ahead of print]PMID: 19862556 [PubMed - as supplied by publisher]Related articles

Polyunsaturated fatty acids effect on serum triglycerides concentration in the presence of metabolic syndrome components. The Alaska-Siberia Project.

Lopez-Alvarenga JC, Ebbesson SO, Ebbesson LO, Tejero ME, Voruganti VS, Comuzzie AG.

Metabolism. 2009 Sep 17. [Epub ahead of print]PMID: 19766268 [PubMed - as supplied by publisher]Related articles

Association of monocyte chemoattractant protein-1 with adipocyte number, insulin resistance and liver function markers.

Bose T, Alvarenga JC, Tejero ME, Voruganti VS, Proffitt JM, Freeland-Graves JH, Cole SA, Comuzzie AG.

J Med Primatol. 2009 Dec;38(6):418-24. Epub 2009 Aug 21.PMID: 19702660 [PubMed - in process]Related articles

Pancreatic islet amyloidosis, beta-cell apoptosis, and alpha-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons.

Guardado-Mendoza R, Davalli AM, Chavez AO, Hubbard GB, Dick EJ, Majluf-Cruz A, Tene-Perez CE, Goldschmidt L, Hart J, Perego C, Comuzzie AG, Tejero ME, Finzi G, Placidi C, La Rosa S, Capella C, Halff G, Gastaldelli A, DeFronzo RA, Folli F.

Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13992-7. Epub 2009 Jul 30.PMID: 19666551 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth hormone-related genes from baboon (Papio hamadryas): Characterization, placental expression and evolutionary aspects.

Rodríguez-Sánchez IP, Tejero ME, Cole SA, Comuzzie AG, Nathanielsz PW, Wallis M, Barrera-Saldaña HA.

Gene. 2009 Aug 3. [Epub ahead of print]PMID: 19651193 [PubMed - as supplied by publisher]Related articles

Feto-placental adaptations to maternal obesity in the baboon.

Farley D, Tejero ME, Comuzzie AG, Higgins PB, Cox L, Werner SL, Jenkins SL, Li C, Choi J, Dick EJ Jr, Hubbard GB, Frost P, Dudley DJ, Ballesteros B, Wu G, Nathanielsz PW, Schlabritz-Loutsevitch NE.

Placenta. 2009 Sep;30(9):752-60. Epub 2009 Jul 25.PMID: 19632719 [PubMed - in process]Related articles

Genetic influence on variation in serum uric acid in American Indians: the strong heart family study.

Voruganti VS, Göring HH, Mottl A, Franceschini N, Haack K, Laston S, Almasy L, Fabsitz RR, Lee ET, Best LG, Devereux RB, Howard BV, MacCluer JW, Comuzzie AG, Umans JG, Cole SA.

Hum Genet. 2009 Nov;126(5):667-76. Epub 2009 Jul 10.PMID: 19590895 [PubMed - in process]Related articles

Evaluation of polymorphisms in paraoxonase 2 (PON2) gene and their association with cardiovascular-renal disease risk in Mexican Americans.

Thameem F, He X, Voruganti VS, Nath SD, Fanti P, Blangero J, Maccluer JW, Comuzzie AG, Arar NH, Abboud HE.

Kidney Blood Press Res. 2009;32(3):200-4. Epub 2009 Jun 18.PMID: 19546579 [PubMed - in process]Related articles

Chemerin is associated with metabolic syndrome phenotypes in a Mexican-American population.

Bozaoglu K, Segal D, Shields KA, Cummings N, Curran JE, Comuzzie AG, Mahaney MC, Rainwater DL, VandeBerg JL, MacCluer JW, Collier G, Blangero J, Walder K, Jowett JB.

J Clin Endocrinol Metab. 2009 Aug;94(8):3085-8. Epub 2009 May 26.PMID: 19470637 [PubMed - indexed for MEDLINE]Related articles

The 27-bp repeat polymorphism in intron 4 (27 bp-VNTR) of endothelial nitric oxide synthase (eNOS) gene is associated with albumin to creatinine ratio in Mexican Americans.

Nath SD, He X, Voruganti VS, Blangero J, MacCluer JW, Comuzzie AG, Arar NH, Abboud HE, Thameem F.

Mol Cell Biochem. 2009 Nov;331(1-2):201-5. Epub 2009 May 26.PMID: 19468830 [PubMed - in process]Related articles

Predictive models of insulin resistance derived from simple morphometric and biochemical indices related to obesity and the metabolic syndrome in baboons.

Chavez AO, Gastaldelli A, Guardado-Mendoza R, Lopez-Alvarenga JC, Leland MM, Tejero ME, Sorice G, Casiraghi F, Davalli A, Bastarrachea RA, Comuzzie AG, DeFronzo RA, Folli F.

Cardiovasc Diabetol. 2009 Apr 23;8:22.PMID: 19389241 [PubMed - in process]Related articlesFree article

Reduced fat oxidation and obesity risks among the Buryat of Southern Siberia.

Leonard WR, Sorensen MV, Mosher MJ, Spitsyn V, Comuzzie AG.

Am J Hum Biol. 2009 Sep-Oct;21(5):664-70.PMID: 19322885 [PubMed - indexed for MEDLINE]Related articles

[Transciptome among Mexicans: a large scale methodology to analyze the genetics expression profile of simultaneous samples in muscle, adipose tissue and lymphocytes obtained from the same individual]

Bastarrachea RA, López-Alvarenga JC, Kent JW Jr, Laviada-Molina HA, Cerda-Flores RM, Calderón-Garcidueñas AL, Torres-Salazar A, Nava-González EJ, Solis-Pérez E, Gallegos-Cabrales EC, Cole SA, Comuzzie AG.

Gac Med Mex. 2008 Nov-Dec;144(6):473-9. Spanish. Erratum in: Gac Med Mex. 2009 Jan-Feb;145(1):78. Torres-Salazar, Amanda [corrected to Torres-Salazar, Amada]. PMID: 19112718 [PubMed - indexed for MEDLINE]Related articles

The prolonged effect of repeated maternal glucocorticoid exposure on the maternal and fetal leptin/insulin-like growth factor axis in Papio species.

Schlabritz-Loutsevitch NE, Lopez-Alvarenga JC, Comuzzie AG, Miller MM, Ford SP, Li C, Hubbard GB, Ferry RJ Jr, Nathanielsz PW.

Reprod Sci. 2009 Mar;16(3):308-19. Epub 2008 Dec 15.PMID: 19087979 [PubMed - indexed for MEDLINE]Related articles

[Reproducibility and sensitivity of the Impact of Weight on Quality of Life questionnaire among obese Mexicans]

Bolado-García VE, López-Alvarenga JC, González-Barranco J, Comuzzie AG.

Gac Med Mex. 2008 Sep-Oct;144(5):419-25. Spanish. PMID: 19043962 [PubMed - indexed for MEDLINE]Related articles

Genetics of variation in serum uric acid and cardiovascular risk factors in Mexican Americans.

Voruganti VS, Nath SD, Cole SA, Thameem F, Jowett JB, Bauer R, MacCluer JW, Blangero J, Comuzzie AG, Abboud HE, Arar NH.

J Clin Endocrinol Metab. 2009 Feb;94(2):632-8. Epub 2008 Nov 11.PMID: 19001525 [PubMed - indexed for MEDLINE]Related articles

Genetic variants in the renin-angiotensin system genes are associated with cardiovascular-renal-related risk factors in Mexican Americans.

Thameem F, Voruganti VS, He X, Nath SD, Blangero J, MacCluer JW, Comuzzie AG, Abboud HE, Arar NH.

Hum Genet. 2008 Dec;124(5):557-9. Epub 2008 Nov 6.PMID: 18985387 [PubMed - indexed for MEDLINE]Related articles

A genetic contribution to circulating cytokines and obesity in children.

Cai G, Cole SA, Butte NF, Smith CW, Mehta NR, Voruganti VS, Proffitt JM, Comuzzie AG.

Cytokine. 2008 Nov;44(2):242-7. Epub 2008 Oct 10.PMID: 18848781 [PubMed - indexed for MEDLINE]Related articlesFree article

Differing definition-based prevalence of metabolic syndrome in the women of Oman family study: a function of multiparity.

Al-barwani SA, Bayoumi RA, Jaju D, Al-Yahyaee SA, Al-Hadabi S, Lopez-Alvarenga JC, Comuzzie AG, Hassan MO.

Metab Syndr Relat Disord. 2008 Fall;6(3):197-202.PMID: 18699722 [PubMed - indexed for MEDLINE]Related articles

Prevalence and heritability of clusters for diagnostic components of metabolic syndrome: the Oman family study.

Lopez-Alvarenga JC, Solís-Herrera C, Kent JW, Jaju D, Albarwani S, Al Yahyahee S, Hassan MO, Bayoumi R, Comuzzie AG.

Metab Syndr Relat Disord. 2008 Summer;6(2):129-35.PMID: 18484902 [PubMed - indexed for MEDLINE]Related articles

[Molecular targets for new drug discovery to treat type 2 diabetes and obesity]

Bastarrachea RA, Montero JC, Saavedra-Gajardo I, Cerda-Flores R, Machado-Domínguez A, Comuzzie AG.

Rev Med Chil. 2008 Jan;136(1):107-17. Epub 2008 Apr 30. Review. Spanish. PMID: 18483661 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait locus on chromosome 12q14.1 influences variation in plasma plasminogen levels in the San Antonio Family Heart Study.

Santamaría A, Diego VP, Almasy L, Rainwater DL, Mahaney MC, Comuzzie AG, Cole SA, Dyer TD, Tracy RP, Stern MP, Maccluer JW, Blangero J.

Hum Biol. 2007 Oct;79(5):515-23.PMID: 18478967 [PubMed - indexed for MEDLINE]Related articles

Cross-species replication of a resistin mRNA QTL, but not QTLs for circulating levels of resistin, in human and baboon.

Tejero ME, Voruganti VS, Proffitt JM, Curran JE, Göring HH, Johnson MP, Dyer TD, Jowett JB, Collier GR, Moses EK, MacCluer JW, Mahaney MC, Blangero J, Comuzzie AG, Cole SA.

Heredity. 2008 Jul;101(1):60-6. Epub 2008 Apr 30.PMID: 18446183 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome-wide search for linkage to chronic kidney disease in a community-based sample: the SAFHS.

Arar NH, Voruganti VS, Nath SD, Thameem F, Bauer R, Cole SA, Blangero J, MacCluer JW, Comuzzie AG, Abboud HE.

Nephrol Dial Transplant. 2008 Oct;23(10):3184-91. Epub 2008 Apr 28.PMID: 18443212 [PubMed - indexed for MEDLINE]Related articlesFree article

Appetite enhancement and weight gain by peripheral administration of TrkB agonists in non-human primates.

Lin JC, Tsao D, Barras P, Bastarrachea RA, Boyd B, Chou J, Rosete R, Long H, Forgie A, Abdiche Y, Dilley J, Stratton J, Garcia C, Sloane DL, Comuzzie AG, Rosenthal A.

PLoS One. 2008 Apr 2;3(4):e1900.PMID: 18382675 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence of smoking and its relationship with carotid atherosclerosis in Alaskan Eskimos of the Norton Sound region: the GOCADAN study.

Kaufman DJ, Roman MJ, Devereux RB, Fabsitz RR, MacCluer JW, Dyke B, Ebbesson SO, Wenger CR, Romanesko T, Comuzzie AG, Howard BV.

Nicotine Tob Res. 2008 Mar;10(3):483-91.PMID: 18324567 [PubMed - indexed for MEDLINE]Related articles

Genome-wide scan revealed genetic loci for energy metabolism in Hispanic children and adolescents.

Cai G, Cole SA, Butte NF, Voruganti VS, Comuzzie AG.

Int J Obes (Lond). 2008 Apr;32(4):579-85. Epub 2008 Mar 4.PMID: 18317473 [PubMed - indexed for MEDLINE]Related articles

Genetics of variation in adiponectin in pedigreed baboons: evidence for pleiotropic effects on adipocyte volume and serum adiponectin.

Tejero ME, Voruganti VS, Rodríguez-Sánchez IP, Proffitt JM, Blangero J, Cox LA, Mahaney MC, Rogers J, VandeBerg JL, Cole SA, Comuzzie AG.

Heredity. 2008 Apr;100(4):382-9. Epub 2008 Feb 20.PMID: 18285814 [PubMed - indexed for MEDLINE]Related articlesFree article

[Macrophages, inflammation, adipose tissue, obesity and insulin resistance]

Bastarrachea RA, López-Alvarenga JC, Bolado-García VE, Téllez-Mendoza J, Laviada-Molina H, Comuzzie AG.

Gac Med Mex. 2007 Nov-Dec;143(6):505-12. Review. Spanish. PMID: 18269082 [PubMed - indexed for MEDLINE]Related articles

Characterization of ghrelin in pedigreed baboons: evidence for heritability and pleiotropy.

Voruganti VS, Tejero ME, Proffitt JM, Cole SA, Cox LA, Mahaney MC, Rogers JA, Freeland-Graves JH, Comuzzie AG.

Obesity (Silver Spring). 2008 Apr;16(4):804-10. Epub 2008 Jan 31.PMID: 18239597 [PubMed - indexed for MEDLINE]Related articles

Genetics of variation in HOMA-IR and cardiovascular risk factors in Mexican-Americans.

Voruganti VS, Lopez-Alvarenga JC, Nath SD, Rainwater DL, Bauer R, Cole SA, Maccluer JW, Blangero J, Comuzzie AG.

J Mol Med. 2008 Mar;86(3):303-11. Epub 2008 Jan 17.PMID: 18204828 [PubMed - indexed for MEDLINE]Related articles

Physiological and molecular determinants of insulin action in the baboon.

Chavez AO, Lopez-Alvarenga JC, Tejero ME, Triplitt C, Bastarrachea RA, Sriwijitkamol A, Tantiwong P, Voruganti VS, Musi N, Comuzzie AG, DeFronzo RA, Folli F.

Diabetes. 2008 Apr;57(4):899-908. Epub 2008 Jan 3.PMID: 18174524 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid consumption and metabolic syndrome components: the GOCADAN study.

Ebbesson SO, Tejero ME, Nobmann ED, Lopez-Alvarenga JC, Ebbesson L, Romenesko T, Carter EA, Resnick HE, Devereux RB, MacCluer JW, Dyke B, Laston SL, Wenger CR, Fabsitz RR, Comuzzie AG, Howard BV.

J Cardiometab Syndr. 2007 Fall;2(4):244-9.PMID: 18059206 [PubMed - indexed for MEDLINE]Related articles

Consumption of omega-3 fatty acids is not associated with a reduction in carotid atherosclerosis: the Genetics of Coronary Artery Disease in Alaska Natives study.

Ebbesson SO, Roman MJ, Devereux RB, Kaufman D, Fabsitz RR, Maccluer JW, Dyke B, Laston S, Wenger CR, Comuzzie AG, Romenesko T, Ebbesson LO, Nobmann ED, Howard BV.

Atherosclerosis. 2008 Aug;199(2):346-53. Epub 2007 Dec 4.PMID: 18054937 [PubMed - indexed for MEDLINE]Related articles

The genes influencing adiponectin levels also influence risk factors for metabolic syndrome and type 2 diabetes.

Comuzzie AG, Tejero ME, Funahashi T, Martin LJ, Kissebah A, Takahashi M, Kihara S, Tanaka S, Rainwater DL, Matsuzawa Y, MacCluer JW, Blangero J.

Hum Biol. 2007 Apr;79(2):191-200.PMID: 18027814 [PubMed - indexed for MEDLINE]Related articles

Heritability and genetic correlations of metabolic disease-related phenotypes in Mexico: preliminary report from the GEMM Family Study.

Bastarrachea RA, Kent JW Jr, Rozada G, Cole SA, López-Alvarenga JC, Aradillas C, Brito-Zurita O, Cerda-Flores RM, Ibarra-Costilla E, Gallegos E, Laviada-Molina H, Hernandez-Escalante V, Rosas J, Machado A, Vadillo F, Ramos M, Lazalde B, Santa-Olalla J, MacCluer JW, Comuzzie AG.

Hum Biol. 2007 Feb;79(1):121-9.PMID: 17985661 [PubMed - indexed for MEDLINE]Related articles

Genome scan for determinants of serum uric acid variability.

Nath SD, Voruganti VS, Arar NH, Thameem F, Lopez-Alvarenga JC, Bauer R, Blangero J, MacCluer JW, Comuzzie AG, Abboud HE.

J Am Soc Nephrol. 2007 Dec;18(12):3156-63. Epub 2007 Oct 31.PMID: 17978310 [PubMed - indexed for MEDLINE]Related articlesFree article

Non-dipping blood pressure in the metabolic syndrome among Arabs of the Oman family study.

Hassan MO, Jaju D, Albarwani S, Al-Yahyaee S, Al-Hadabi S, Lopez-Alvarenga JC, Rizvi SG, Comuzzie AG, Bayoumi RA.

Obesity (Silver Spring). 2007 Oct;15(10):2445-53.PMID: 17925470 [PubMed - indexed for MEDLINE]Related articles

A quantitative trait locus on chromosome 13q affects fasting glucose levels in Hispanic children.

Cai G, Cole SA, Butte NF, Voruganti VS, Comuzzie AG.

J Clin Endocrinol Metab. 2007 Dec;92(12):4893-6. Epub 2007 Oct 9.PMID: 17925332 [PubMed - indexed for MEDLINE]Related articlesFree article

Meta-analysis of genome-wide linkage studies in BMI and obesity.

Saunders CL, Chiodini BD, Sham P, Lewis CM, Abkevich V, Adeyemo AA, de Andrade M, Arya R, Berenson GS, Blangero J, Boehnke M, Borecki IB, Chagnon YC, Chen W, Comuzzie AG, Deng HW, Duggirala R, Feitosa MF, Froguel P, Hanson RL, Hebebrand J, Huezo-Dias P, Kissebah AH, Li W, Luke A, Martin LJ, Nash M, Ohman M, Palmer LJ, Peltonen L, Perola M, Price RA, Redline S, Srinivasan SR, Stern MP, Stone S, Stringham H, Turner S, Wijmenga C, Collier DA.

Obesity (Silver Spring). 2007 Sep;15(9):2263-75.PMID: 17890495 [PubMed - indexed for MEDLINE]Related articles

Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes.

Göring HH, Curran JE, Johnson MP, Dyer TD, Charlesworth J, Cole SA, Jowett JB, Abraham LJ, Rainwater DL, Comuzzie AG, Mahaney MC, Almasy L, MacCluer JW, Kissebah AH, Collier GR, Moses EK, Blangero J.

Nat Genet. 2007 Oct;39(10):1208-16. Epub 2007 Sep 16.PMID: 17873875 [PubMed - indexed for MEDLINE]Related articles

A chromosome 11q quantitative-trait locus influences change of blood-pressure measurements over time in Mexican Americans of the San Antonio Family Heart Study.

Rutherford S, Cai G, Lopez-Alvarenga JC, Kent JW, Voruganti VS, Proffitt JM, Curran JE, Johnson MP, Dyer TD, Jowett JB, Bastarrachea RA, Atwood LD, Goring HH, Maccluer JW, Moses EK, Blangero J, Comuzzie AG, Cole SA.

Am J Hum Genet. 2007 Oct;81(4):744-55. Epub 2007 Aug 20.PMID: 17846999 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide scan of plasma cholecystokinin in baboons shows linkage to human chromosome 17.

Voruganti VS, Tejero ME, Proffitt JM, Cole SA, Freeland-Graves JH, Comuzzie AG.

Obesity (Silver Spring). 2007 Aug;15(8):2043-50.PMID: 17712122 [PubMed - indexed for MEDLINE]Related articles

The end of the beginning.

Cole SA, Comuzzie AG.

Am J Clin Nutr. 2007 Aug;86(2):274-5. No abstract available. PMID: 17684195 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide scan for serum ghrelin detects linkage on chromosome 1p36 in Hispanic children: results from the Viva La Familia study.

Voruganti VS, Göring HH, Diego VP, Cai G, Mehta NR, Haack K, Cole SA, Butte NF, Comuzzie AG.

Pediatr Res. 2007 Oct;62(4):445-50.PMID: 17667848 [PubMed - indexed for MEDLINE]Related articles

[Patients with type III obesity given sibutramine 15 mg/day lose weight in amounts proportional to those in types I and II, but waist circumferences does not decrease proportionally]

López-Alvarenga JC, Vargas JA, Schneider-Ehrenberg OP, Comuzzie AG, González J, Martínez JL.

Gac Med Mex. 2007 Mar-Apr;143(2):109-14. Spanish. PMID: 17585697 [PubMed - indexed for MEDLINE]Related articles

[Study of the genetic component of cardiovascular risk phenotypes in a Mexican population]

Bastarrachea RA, Kent J Jr, Comuzzie AG.

Med Clin (Barc). 2007 Jun 2;129(1):11-3. Spanish. PMID: 17570180 [PubMed - indexed for MEDLINE]Related articles

Heritability of hyperphagic eating behavior and appetite-related hormones among Hispanic children.

Fisher JO, Cai G, Jaramillo SJ, Cole SA, Comuzzie AG, Butte NF.

Obesity (Silver Spring). 2007 Jun;15(6):1484-95.PMID: 17557986 [PubMed - indexed for MEDLINE]Related articles

Metabolic and behavioral predictors of weight gain in Hispanic children: the Viva la Familia Study.

Butte NF, Cai G, Cole SA, Wilson TA, Fisher JO, Zakeri IF, Ellis KJ, Comuzzie AG.

Am J Clin Nutr. 2007 Jun;85(6):1478-85.PMID: 17556682 [PubMed - indexed for MEDLINE]Related articlesFree article