PubMed

Emerging drugs for the treatment of ulcerative colitis.

Pastorelli L, Pizarro TT, Cominelli F, Vecchi M.

Expert Opin Emerg Drugs. 2009 Sep;14(3):505-21. Review.PMID: 19656075 [PubMed - indexed for MEDLINE]Related articles

Leukocytapheresis in ulcerative colitis: a possible alternative to biological therapy?

Arseneau KO, Cominelli F.

Dig Liver Dis. 2009 Aug;41(8):551-2. Epub 2009 Jun 21. No abstract available. PMID: 19540820 [PubMed - indexed for MEDLINE]Related articles

AGA Institute Future Trends Committee report: the future of gastroenterology training programs in the United States.

Wang TC, Cominelli F, Fleischer DE, Gordon JM, Glickman RM, Limsui D, McQuaid KR, Montrose M, Pasricha PJ, Powell DW, Rowe WA, Sandborn WJ, Todisco A.

Gastroenterology. 2008 Nov;135(5):1764-89.e2. No abstract available. PMID: 19009690 [PubMed - indexed for MEDLINE]Related articles

Commensal bacteria and "oncologic surveillance": suggestions from an experimental model.

Pagnini C, Corleto VD, Hoang SB, Saeed R, Cominelli F, Delle Fave G.

J Clin Gastroenterol. 2008 Sep;42 Suppl 3 Pt 2:S193-6.PMID: 18685507 [PubMed - indexed for MEDLINE]Related articles

Early and late gut immune responses in IBD.

Cominelli F.

J Pediatr Gastroenterol Nutr. 2008 Apr;46 Suppl 1:E20. Review. No abstract available. PMID: 18354325 [PubMed - indexed for MEDLINE]Related articles

Innate and adaptive immune responses related to IBD pathogenesis.

Arseneau KO, Tamagawa H, Pizarro TT, Cominelli F.

Curr Gastroenterol Rep. 2007 Dec;9(6):508-12. Review.PMID: 18377804 [PubMed - indexed for MEDLINE]Related articles

A CD8+/CD103high T cell subset regulates TNF-mediated chronic murine ileitis.

Ho J, Kurtz CC, Naganuma M, Ernst PB, Cominelli F, Rivera-Nieves J.

J Immunol. 2008 Feb 15;180(4):2573-80.PMID: 18250468 [PubMed - indexed for MEDLINE]Related articlesFree article

MNK kinases regulate multiple TLR pathways and innate proinflammatory cytokines in macrophages.

Rowlett RM, Chrestensen CA, Nyce M, Harp MG, Pelo JW, Cominelli F, Ernst PB, Pizarro TT, Sturgill TW, Worthington MT.

Am J Physiol Gastrointest Liver Physiol. 2008 Feb;294(2):G452-9. Epub 2007 Nov 21.PMID: 18032482 [PubMed - indexed for MEDLINE]Related articlesFree article

Resistin-like molecule beta (RELMbeta/FIZZ2) is highly expressed in the ileum of SAMP1/YitFc mice and is associated with initiation of ileitis.

Barnes SL, Vidrich A, Wang ML, Wu GD, Cominelli F, Rivera-Nieves J, Bamias G, Cohn SM.

J Immunol. 2007 Nov 15;179(10):7012-20.PMID: 17982092 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunopathogenesis of inflammatory bowel disease: current concepts.

Bamias G, Cominelli F.

Curr Opin Gastroenterol. 2007 Jul;23(4):365-9. Review.PMID: 17545770 [PubMed - indexed for MEDLINE]Related articles

Report of the American Gastroenterological Association (AGA) Institute Obesity Task Force.

Kaplan LM, Klein S, Boden G, Brenner DA, Gostout CJ, Lavine JE, Popkin BM, Schirmer BD, Seeley RJ, Yanovski SZ, Cominelli F.

Gastroenterology. 2007 May;132(6):2272-5. No abstract available. PMID: 17498517 [PubMed - indexed for MEDLINE]Related articles

Cloning IL-1 and the birth of a new era in cytokine biology.

Pizarro TT, Cominelli F.

J Immunol. 2007 May 1;178(9):5411-2. No abstract available. PMID: 17442919 [PubMed - indexed for MEDLINE]Related articlesFree article

Probiotics in experimental and human inflammatory bowel disease: discussion points.

Pagnini C, Cominelli F.

Dig Liver Dis. 2006 Dec;38 Suppl 2:S270-3. Review.PMID: 17259089 [PubMed - indexed for MEDLINE]Related articles

The attrition of young physician-scientists: problems and potential solutions.

Donowitz M, Germino G, Cominelli F, Anderson JM.

Gastroenterology. 2007 Feb;132(2):477-80.PMID: 17258744 [PubMed - indexed for MEDLINE]Related articles

Commensal bacteria exacerbate intestinal inflammation but are not essential for the development of murine ileitis.

Bamias G, Okazawa A, Rivera-Nieves J, Arseneau KO, De La Rue SA, Pizarro TT, Cominelli F.

J Immunol. 2007 Feb 1;178(3):1809-18.PMID: 17237431 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokine therapy for Crohn's disease: advances in translational research.

Pizarro TT, Cominelli F.

Annu Rev Med. 2007;58:433-44. Review.PMID: 17217333 [PubMed - indexed for MEDLINE]Related articles

Antibody blockade of CCL25/CCR9 ameliorates early but not late chronic murine ileitis.

Rivera-Nieves J, Ho J, Bamias G, Ivashkina N, Ley K, Oppermann M, Cominelli F.

Gastroenterology. 2006 Nov;131(5):1518-29. Epub 2006 Aug 16.PMID: 17101325 [PubMed - indexed for MEDLINE]Related articles

Discovering the cause of inflammatory bowel disease: lessons from animal models.

Arseneau KO, Pizarro TT, Cominelli F.

Curr Opin Gastroenterol. 2000 Jul;16(4):310-7.PMID: 17031094 [PubMed]Related articles

Absence of bacterially induced RELMbeta reduces injury in the dextran sodium sulfate model of colitis.

McVay LD, Keilbaugh SA, Wong TM, Kierstein S, Shin ME, Lehrke M, Lefterova MI, Shifflett DE, Barnes SL, Cominelli F, Cohn SM, Hecht G, Lazar MA, Haczku A, Wu GD.

J Clin Invest. 2006 Nov;116(11):2914-23. Epub 2006 Oct 5.PMID: 17024245 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of interleukin 6 in a murine model of Crohn's ileitis: are cytokine/anticytokine strategies the future for IBD therapies?

Pizarro TT, De La Rue SA, Cominelli F.

Gut. 2006 Sep;55(9):1226-7.PMID: 16905692 [PubMed - indexed for MEDLINE]Related articlesFree article

Do patient preferences influence decisions on treatment for patients with steroid-refractory ulcerative colitis?

Arseneau KO, Sultan S, Provenzale DT, Onken J, Bickston SJ, Foley E, Connors AF Jr, Cominelli F.

Clin Gastroenterol Hepatol. 2006 Sep;4(9):1135-42. Epub 2006 Jul 10.PMID: 16829206 [PubMed - indexed for MEDLINE]Related articles

Novel strategies to attenuate immune activation in Crohn's disease.

Bamias G, Cominelli F.

Curr Opin Pharmacol. 2006 Aug;6(4):401-7. Epub 2006 Jun 5. Review.PMID: 16753341 [PubMed - indexed for MEDLINE]Related articles

Role of TL1A and its receptor DR3 in two models of chronic murine ileitis.

Bamias G, Mishina M, Nyce M, Ross WG, Kollias G, Rivera-Nieves J, Pizarro TT, Cominelli F.

Proc Natl Acad Sci U S A. 2006 May 30;103(22):8441-6. Epub 2006 May 12.PMID: 16698931 [PubMed - indexed for MEDLINE]Related articlesFree article

Critical role of endothelial P-selectin glycoprotein ligand 1 in chronic murine ileitis.

Rivera-Nieves J, Burcin TL, Olson TS, Morris MA, McDuffie M, Cominelli F, Ley K.

J Exp Med. 2006 Apr 17;203(4):907-17. Epub 2006 Mar 27.PMID: 16567389 [PubMed - indexed for MEDLINE]Related articlesFree article

The primary defect in experimental ileitis originates from a nonhematopoietic source.

Olson TS, Reuter BK, Scott KG, Morris MA, Wang XM, Hancock LN, Burcin TL, Cohn SM, Ernst PB, Cominelli F, Meddings JB, Ley K, Pizarro TT.

J Exp Med. 2006 Mar 20;203(3):541-52. Epub 2006 Feb 27.PMID: 16505137 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease.

Bachmann C, Klibanov AL, Olson TS, Sonnenschein JR, Rivera-Nieves J, Cominelli F, Ley KF, Lindner JR, Pizarro TT.

Gastroenterology. 2006 Jan;130(1):8-16.PMID: 16401463 [PubMed - indexed for MEDLINE]Related articles

New concepts in the pathophysiology of inflammatory bowel disease.

Bamias G, Nyce MR, De La Rue SA, Cominelli F; American College of Physicians; American Physiological Society.

Ann Intern Med. 2005 Dec 20;143(12):895-904. Review. No abstract available. PMID: 16365470 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease.

Odashima M, Bamias G, Rivera-Nieves J, Linden J, Nast CC, Moskaluk CA, Marini M, Sugawara K, Kozaiwa K, Otaka M, Watanabe S, Cominelli F.

Gastroenterology. 2005 Jul;129(1):26-33.PMID: 16012931 [PubMed - indexed for MEDLINE]Related articles

Altered epithelial cell lineage allocation and global expansion of the crypt epithelial stem cell population are associated with ileitis in SAMP1/YitFc mice.

Vidrich A, Buzan JM, Barnes S, Reuter BK, Skaar K, Ilo C, Cominelli F, Pizarro T, Cohn SM.

Am J Pathol. 2005 Apr;166(4):1055-67.PMID: 15793286 [PubMed - indexed for MEDLINE]Related articlesFree article

Proinflammatory effects of TH2 cytokines in a murine model of chronic small intestinal inflammation.

Bamias G, Martin C, Mishina M, Ross WG, Rivera-Nieves J, Marini M, Cominelli F.

Gastroenterology. 2005 Mar;128(3):654-66.PMID: 15765401 [PubMed - indexed for MEDLINE]Related articles

A randomized, double-blind, placebo-controlled trial of CDP571, a humanized monoclonal antibody to tumour necrosis factor-alpha, in patients with corticosteroid-dependent Crohn's disease.

Feagan BG, Sandborn WJ, Baker JP, Cominelli F, Sutherland LR, Elson CO, Salzberg BA, Archambault A, Bernstein CN, Lichtenstein GR, Heath PK, Cameron S, Hanauer SB.

Aliment Pharmacol Ther. 2005 Feb 15;21(4):373-84.PMID: 15709987 [PubMed - indexed for MEDLINE]Related articlesFree article

L-selectin, alpha 4 beta 1, and alpha 4 beta 7 integrins participate in CD4+ T cell recruitment to chronically inflamed small intestine.

Rivera-Nieves J, Olson T, Bamias G, Bruce A, Solga M, Knight RF, Hoang S, Cominelli F, Ley K.

J Immunol. 2005 Feb 15;174(4):2343-52.PMID: 15699171 [PubMed - indexed for MEDLINE]Related articlesFree article

Linkage to peroxisome proliferator-activated receptor-gamma in SAMP1/YitFc mice and in human Crohn's disease.

Sugawara K, Olson TS, Moskaluk CA, Stevens BK, Hoang S, Kozaiwa K, Cominelli F, Ley KF, McDuffie M.

Gastroenterology. 2005 Feb;128(2):351-60.PMID: 15685547 [PubMed - indexed for MEDLINE]Related articles

Cytokine-based therapies for Crohn's disease--new paradigms.

Cominelli F.

N Engl J Med. 2004 Nov 11;351(20):2045-8. No abstract available. PMID: 15537904 [PubMed - indexed for MEDLINE]Related articles

Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease.

Olson TS, Bamias G, Naganuma M, Rivera-Nieves J, Burcin TL, Ross W, Morris MA, Pizarro TT, Ernst PB, Cominelli F, Ley K.

J Clin Invest. 2004 Aug;114(3):389-98.PMID: 15286805 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential contribution of IL-1Ra isoforms to allele-specific IL-1Ra mRNA accumulation.

Redlitz KH, Yamshchikov VF, Cominelli F.

J Interferon Cytokine Res. 2004 Apr;24(4):253-60.PMID: 15144571 [PubMed - indexed for MEDLINE]Related articles

Optimal dosing of 5-aminosalicylic acid: 5 decades of choosing between politicians.

Bickston SJ, Cominelli F.

Clin Gastroenterol Hepatol. 2003 Jan;1(1):3-4. No abstract available. PMID: 15017510 [PubMed - indexed for MEDLINE]Related articles

Effect of digestive health care services integration on resource use and outcomes in patients with digestive disorders.

Arseneau KO, Yeaton P, Kahaleh M, Cominelli F.

Clin Gastroenterol Hepatol. 2003 Mar;1(2):145-51.PMID: 15017507 [PubMed - indexed for MEDLINE]Related articles

The Th1 immune pathway as a therapeutic target in Crohn's disease.

Bamias G, Sugawara K, Pagnini C, Cominelli F.

Curr Opin Investig Drugs. 2003 Nov;4(11):1279-86. Review.PMID: 14758766 [PubMed - indexed for MEDLINE]Related articles

Future therapies for inflammatory bowel disease.

Bickston SJ, Comerford LW, Cominelli F.

Curr Gastroenterol Rep. 2003 Dec;5(6):518-23. Review.PMID: 14602063 [PubMed - indexed for MEDLINE]Related articles

Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease.

Bamias G, Martin C 3rd, Marini M, Hoang S, Mishina M, Ross WG, Sachedina MA, Friel CM, Mize J, Bickston SJ, Pizarro TT, Wei P, Cominelli F.

J Immunol. 2003 Nov 1;171(9):4868-74.PMID: 14568967 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a quantitative trait locus for ileitis in a spontaneous mouse model of Crohn's disease: SAMP1/YitFc.

Kozaiwa K, Sugawara K, Smith MF Jr, Carl V, Yamschikov V, Belyea B, McEwen SB, Moskaluk CA, Pizarro TT, Cominelli F, McDuffie M.

Gastroenterology. 2003 Aug;125(2):477-90.PMID: 12891551 [PubMed - indexed for MEDLINE]Related articles

TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis.

Marini M, Bamias G, Rivera-Nieves J, Moskaluk CA, Hoang SB, Ross WG, Pizarro TT, Cominelli F.

Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8366-71. Epub 2003 Jun 27.PMID: 12832622 [PubMed - indexed for MEDLINE]Related articlesFree article

Mouse models for the study of Crohn's disease.

Pizarro TT, Arseneau KO, Bamias G, Cominelli F.

Trends Mol Med. 2003 May;9(5):218-22. Review.PMID: 12763527 [PubMed - indexed for MEDLINE]Related articles

Emergence of perianal fistulizing disease in the SAMP1/YitFc mouse, a spontaneous model of chronic ileitis.

Rivera-Nieves J, Bamias G, Vidrich A, Marini M, Pizarro TT, McDuffie MJ, Moskaluk CA, Cohn SM, Cominelli F.

Gastroenterology. 2003 Apr;124(4):972-82.PMID: 12671894 [PubMed - indexed for MEDLINE]Related articles

Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease.

Kontoyiannis D, Boulougouris G, Manoloukos M, Armaka M, Apostolaki M, Pizarro T, Kotlyarov A, Forster I, Flavell R, Gaestel M, Tsichlis P, Cominelli F, Kollias G.

J Exp Med. 2002 Dec 16;196(12):1563-74.PMID: 12486099 [PubMed - indexed for MEDLINE]Related articlesFree article

Down-regulation of intestinal lymphocyte activation and Th1 cytokine production by antibiotic therapy in a murine model of Crohn's disease.

Bamias G, Marini M, Moskaluk CA, Odashima M, Ross WG, Rivera-Nieves J, Cominelli F.

J Immunol. 2002 Nov 1;169(9):5308-14.PMID: 12391251 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of misoprostol on ibuprofen-induced renal dysfunction in patients with decompensated cirrhosis: results of a double-blind placebo-controlled parallel group study.

Ackerman Z, Cominelli F, Reynolds TB.

Am J Gastroenterol. 2002 Aug;97(8):2033-9.PMID: 12190173 [PubMed - indexed for MEDLINE]Related articles

A possible role of IL-1ra 3'-untranslated region in modulation of protein production.

Yamshchikov VF, Mishina M, Cominelli F.

Cytokine. 2002 Jan 21;17(2):98-107.PMID: 11886177 [PubMed - indexed for MEDLINE]Related articles

Intestinal ischemia and peripheral gangrene in a patient with chronic renal failure.

Rivera-Nieves J, Bamias G, Alfert J, Bickston SJ, Moskaluk CA, Cominelli F.

Gastroenterology. 2002 Feb;122(2):495-9.PMID: 11832463 [PubMed - indexed for MEDLINE]Related articles