PubMed

Human papillomavirus 16 E7 inactivator of retinoblastoma family proteins complements human cytomegalovirus lacking UL97 protein kinase.

Kamil JP, Hume AJ, Jurak I, Münger K, Kalejta RF, Coen DM.

Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16823-8. Epub 2009 Sep 15.PMID: 19805380 [PubMed - in process]Related articles

The crystal structure of PF-8, the DNA polymerase accessory subunit from Kaposi's sarcoma-associated herpesvirus.

Baltz JL, Filman DJ, Ciustea M, Silverman JE, Lautenschlager CL, Coen DM, Ricciardi RP, Hogle JM.

J Virol. 2009 Dec;83(23):12215-28. Epub 2009 Sep 16.PMID: 19759157 [PubMed - in process]Related articles

Mutations that increase DNA binding by the processivity factor of herpes simplex virus affect virus production and DNA replication fidelity.

Jiang C, Komazin-Meredith G, Tian W, Coen DM, Hwang CB.

J Virol. 2009 Aug;83(15):7573-80. Epub 2009 May 27.PMID: 19474109 [PubMed - indexed for MEDLINE]Related articles

Analysis of the association of the human cytomegalovirus DNA polymerase subunit UL44 with the viral DNA replication factor UL84.

Strang BL, Sinigalia E, Silva LA, Coen DM, Loregian A.

J Virol. 2009 Aug;83(15):7581-9. Epub 2009 May 20.PMID: 19457994 [PubMed - indexed for MEDLINE]Related articles

Viral mimicry of Cdc2/cyclin-dependent kinase 1 mediates disruption of nuclear lamina during human cytomegalovirus nuclear egress.

Hamirally S, Kamil JP, Ndassa-Colday YM, Lin AJ, Jahng WJ, Baek MC, Noton S, Silva LA, Simpson-Holley M, Knipe DM, Golan DE, Marto JA, Coen DM.

PLoS Pathog. 2009 Jan;5(1):e1000275. Epub 2009 Jan 23.PMID: 19165338 [PubMed - indexed for MEDLINE]Related articlesFree article

Biochemical, biophysical, and mutational analyses of subunit interactions of the human cytomegalovirus nuclear egress complex.

Sam MD, Evans BT, Coen DM, Hogle JM.

J Virol. 2009 Apr;83(7):2996-3006. Epub 2009 Jan 19.PMID: 19153235 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of homodimerization of human cytomegalovirus DNA polymerase accessory protein UL44 in origin-dependent DNA replication in cells.

Sinigalia E, Alvisi G, Mercorelli B, Coen DM, Pari GS, Jans DA, Ripalti A, Palù G, Loregian A.

J Virol. 2008 Dec;82(24):12574-9. Epub 2008 Oct 8.PMID: 18842734 [PubMed - indexed for MEDLINE]Related articlesFree article

Enzymatic amplification of DNA by PCR: standard procedures and optimization.

Kramer MF, Coen DM.

Curr Protoc Cytom. 2006 Aug;Appendix 3:Appendix 3K.PMID: 18770830 [PubMed - indexed for MEDLINE]Related articles

ICP34.5-dependent and -independent activities of salubrinal in herpes simplex virus-1 infected cells.

Bryant KF, Macari ER, Malik N, Boyce M, Yuan J, Coen DM.

Virology. 2008 Sep 30;379(2):197-204. Epub 2008 Aug 6.PMID: 18684481 [PubMed - indexed for MEDLINE]Related articlesFree article

The human cytomegalovirus UL44 C clamp wraps around DNA.

Komazin-Meredith G, Petrella RJ, Santos WL, Filman DJ, Hogle JM, Verdine GL, Karplus M, Coen DM.

Structure. 2008 Aug 6;16(8):1214-25.PMID: 18682223 [PubMed - indexed for MEDLINE]Related articles

Hopping of a processivity factor on DNA revealed by single-molecule assays of diffusion.

Komazin-Meredith G, Mirchev R, Golan DE, van Oijen AM, Coen DM.

Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10721-6. Epub 2008 Jul 25.PMID: 18658237 [PubMed - indexed for MEDLINE]Related articlesFree article

MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs.

Umbach JL, Kramer MF, Jurak I, Karnowski HW, Coen DM, Cullen BR.

Nature. 2008 Aug 7;454(7205):780-3. Epub 2008 Jul 2.PMID: 18596690 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of retinoblastoma protein by viral protein with cyclin-dependent kinase function.

Hume AJ, Finkel JS, Kamil JP, Coen DM, Culbertson MR, Kalejta RF.

Science. 2008 May 9;320(5877):797-9.PMID: 18467589 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitation of rare DNAs by PCR.

Coen DM.

Curr Protoc Immunol. 2001 May;Chapter 10:Unit 10.21. Review.PMID: 18432686 [PubMed - indexed for MEDLINE]Related articles

Enzymatic amplification of DNA by PCR: standard procedures and optimization.

Kramer MF, Coen DM.

Curr Protoc Immunol. 2001 May;Chapter 10:Unit 10.20. Review.PMID: 18432685 [PubMed - indexed for MEDLINE]Related articles

The polymerase chain reaction.

Kramer MF, Coen DM.

Curr Protoc Protein Sci. 2002 Nov;Appendix 4:Appendix 4J.PMID: 18429219 [PubMed - indexed for MEDLINE]Related articles

Quantitation of rare DNAs by PCR.

Coen DM.

Curr Protoc Mol Biol. 2001 Nov;Chapter 15:Unit 15.7.PMID: 18265121 [PubMed - indexed for MEDLINE]Related articles

Enzymatic amplification of DNA by PCR: standard procedures and optimization.

Kramer MF, Coen DM.

Curr Protoc Mol Biol. 2001 Nov;Chapter 15:Unit 15.1.PMID: 18265115 [PubMed - indexed for MEDLINE]Related articles

Enzymatic amplification of DNA by PCR: standard procedures and optimization.

Kramer MF, Coen DM.

Curr Protoc Cell Biol. 2001 May;Appendix 3:Appendix 3F.PMID: 18228288 [PubMed - indexed for MEDLINE]Related articles

The positively charged surface of herpes simplex virus UL42 mediates DNA binding.

Komazin-Meredith G, Santos WL, Filman DJ, Hogle JM, Verdine GL, Coen DM.

J Biol Chem. 2008 Mar 7;283(10):6154-61. Epub 2008 Jan 4.PMID: 18178550 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of translation by a short element in the 5' leader of the herpes simplex virus 1 DNA polymerase transcript.

Bryant KF, Coen DM.

J Virol. 2008 Jan;82(1):77-85. Epub 2007 Oct 24.PMID: 17959669 [PubMed - indexed for MEDLINE]Related articlesFree article

Herpes simplex virus mutants with multiple substitutions affecting DNA binding of UL42 are impaired for viral replication and DNA synthesis.

Jiang C, Hwang YT, Wang G, Randell JC, Coen DM, Hwang CB.

J Virol. 2007 Nov;81(21):12077-9. Epub 2007 Aug 22.PMID: 17715219 [PubMed - indexed for MEDLINE]Related articlesFree article

Human cytomegalovirus protein kinase UL97 forms a complex with the tegument phosphoprotein pp65.

Kamil JP, Coen DM.

J Virol. 2007 Oct;81(19):10659-68. Epub 2007 Jul 18. Erratum in: J Virol. 2007 Dec;81(23):13277. PMID: 17634236 [PubMed - indexed for MEDLINE]Related articlesFree article

Binding parameters and thermodynamics of the interaction of the human cytomegalovirus DNA polymerase accessory protein, UL44, with DNA: implications for the processivity mechanism.

Loregian A, Sinigalia E, Mercorelli B, Palù G, Coen DM.

Nucleic Acids Res. 2007;35(14):4779-91. Epub 2007 Jul 7.PMID: 17617644 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibitors of the sodium potassium ATPase that impair herpes simplex virus replication identified via a chemical screening approach.

Dodson AW, Taylor TJ, Knipe DM, Coen DM.

Virology. 2007 Sep 30;366(2):340-8. Epub 2007 Jun 1.PMID: 17544048 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of extremely low levels of thymidine kinase from an acyclovir-resistant herpes simplex virus mutant supports reactivation from latently infected mouse trigeminal ganglia.

Besecker MI, Furness CL, Coen DM, Griffiths A.

J Virol. 2007 Aug;81(15):8356-60. Epub 2007 May 23.PMID: 17522225 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo fitness and virulence of a drug-resistant herpes simplex virus 1 mutant.

Pesola JM, Coen DM.

J Gen Virol. 2007 May;88(Pt 5):1410-4.PMID: 17412967 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutations that decrease DNA binding of the processivity factor of the herpes simplex virus DNA polymerase reduce viral yield, alter the kinetics of viral DNA replication, and decrease the fidelity of DNA replication.

Jiang C, Hwang YT, Randell JC, Coen DM, Hwang CB.

J Virol. 2007 Apr;81(7):3495-502. Epub 2007 Jan 17.PMID: 17229696 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-level expression and reversion both contribute to reactivation of herpes simplex virus drug-resistant mutants with mutations on homopolymeric sequences in thymidine kinase.

Griffiths A, Link MA, Furness CL, Coen DM.

J Virol. 2006 Jul;80(13):6568-74.PMID: 16775343 [PubMed - indexed for MEDLINE]Related articlesFree article

Prediction and identification of herpes simplex virus 1-encoded microRNAs.

Cui C, Griffiths A, Li G, Silva LM, Kramer MF, Gaasterland T, Wang XJ, Coen DM.

J Virol. 2006 Jun;80(11):5499-508.PMID: 16699030 [PubMed - indexed for MEDLINE]Related articlesFree article

Virucidal activity of a GT-rich oligonucleotide against herpes simplex virus mediated by glycoprotein B.

Shogan B, Kruse L, Mulamba GB, Hu A, Coen DM.

J Virol. 2006 May;80(10):4740-7.PMID: 16641267 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase.

Loregian A, Coen DM.

Chem Biol. 2006 Feb;13(2):191-200.PMID: 16492567 [PubMed - indexed for MEDLINE]Related articles

Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44.

Appleton BA, Brooks J, Loregian A, Filman DJ, Coen DM, Hogle JM.

J Biol Chem. 2006 Feb 24;281(8):5224-32. Epub 2005 Dec 20.PMID: 16371349 [PubMed - indexed for MEDLINE]Related articlesFree article

Herpes simplex virus 1 immediate-early and early gene expression during reactivation from latency under conditions that prevent infectious virus production.

Pesola JM, Zhu J, Knipe DM, Coen DM.

J Virol. 2005 Dec;79(23):14516-25. Erratum in: J Virol. 2006 Jun;80(12):6196. PMID: 16282451 [PubMed - indexed for MEDLINE]Related articlesFree article

Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection.

Wang QY, Zhou C, Johnson KE, Colgrove RC, Coen DM, Knipe DM.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16055-9. Epub 2005 Oct 24.PMID: 16247011 [PubMed - indexed for MEDLINE]Related articlesFree article

Binding of herpes simplex virus-1 US11 to specific RNA sequences.

Bryant KF, Cox JC, Wang H, Hogle JM, Ellington AD, Coen DM.

Nucleic Acids Res. 2005 Oct 24;33(19):6090-100. Print 2005.PMID: 16246910 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of substitutions of arginine residues on the basic surface of herpes simplex virus UL42 support a role for DNA binding in processive DNA synthesis.

Randell JC, Komazin G, Jiang C, Hwang CB, Coen DM.

J Virol. 2005 Sep;79(18):12025-34.PMID: 16140778 [PubMed - indexed for MEDLINE]Related articlesFree article

An unusual internal ribosome entry site in the herpes simplex virus thymidine kinase gene.

Griffiths A, Coen DM.

Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9667-72. Epub 2005 Jun 22.PMID: 15972803 [PubMed - indexed for MEDLINE]Related articlesFree article

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress.

Boyce M, Bryant KF, Jousse C, Long K, Harding HP, Scheuner D, Kaufman RJ, Ma D, Coen DM, Ron D, Yuan J.

Science. 2005 Feb 11;307(5711):935-9.PMID: 15705855 [PubMed - indexed for MEDLINE]Related articlesFree article

Persistent expression of chemokine and chemokine receptor RNAs at primary and latent sites of herpes simplex virus 1 infection.

Cook WJ, Kramer MF, Walker RM, Burwell TJ, Holman HA, Coen DM, Knipe DM.

Virol J. 2004 Sep 23;1:5.PMID: 15507126 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein UL44 are crucial for interaction with the UL54 catalytic subunit.

Loregian A, Appleton BA, Hogle JM, Coen DM.

J Virol. 2004 Sep;78(17):9084-92.PMID: 15308704 [PubMed - indexed for MEDLINE]Related articlesFree article

The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer.

Appleton BA, Loregian A, Filman DJ, Coen DM, Hogle JM.

Mol Cell. 2004 Jul 23;15(2):233-44.PMID: 15260974 [PubMed - indexed for MEDLINE]Related articles

Phosphorylation of the RNA polymerase II carboxyl-terminal domain in human cytomegalovirus-infected cells and in vitro by the viral UL97 protein kinase.

Baek MC, Krosky PM, Pearson A, Coen DM.

Virology. 2004 Jun 20;324(1):184-93.PMID: 15183065 [PubMed - indexed for MEDLINE]Related articles

Identification of a small molecule that inhibits herpes simplex virus DNA Polymerase subunit interactions and viral replication.

Pilger BD, Cui C, Coen DM.

Chem Biol. 2004 May;11(5):647-54.PMID: 15157875 [PubMed - indexed for MEDLINE]Related articles

The herpes simplex virus processivity factor, UL42, binds DNA as a monomer.

Randell JC, Coen DM.

J Mol Biol. 2004 Jan 9;335(2):409-13.PMID: 14672651 [PubMed - indexed for MEDLINE]Related articles

Failure of thymidine kinase-negative herpes simplex virus to reactivate from latency following efficient establishment.

Chen SH, Pearson A, Coen DM, Chen SH.

J Virol. 2004 Jan;78(1):520-3.PMID: 14671133 [PubMed - indexed for MEDLINE]Related articlesFree article

Residues of human cytomegalovirus DNA polymerase catalytic subunit UL54 that are necessary and sufficient for interaction with the accessory protein UL44.

Loregian A, Appleton BA, Hogle JM, Coen DM.

J Virol. 2004 Jan;78(1):158-67.PMID: 14671097 [PubMed - indexed for MEDLINE]Related articlesFree article

ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cells.

Pearson A, Knipe DM, Coen DM.

J Virol. 2004 Jan;78(1):23-32.PMID: 14671084 [PubMed - indexed for MEDLINE]Related articlesFree article

Latent herpes simplex virus infection of sensory neurons alters neuronal gene expression.

Kramer MF, Cook WJ, Roth FP, Zhu J, Holman H, Knipe DM, Coen DM.

J Virol. 2003 Sep;77(17):9533-41.PMID: 12915567 [PubMed - indexed for MEDLINE]Related articlesFree article

The human cytomegalovirus UL44 protein is a substrate for the UL97 protein kinase.

Krosky PM, Baek MC, Jahng WJ, Barrera I, Harvey RJ, Biron KK, Coen DM, Sethna PB.

J Virol. 2003 Jul;77(14):7720-7.PMID: 12829811 [PubMed - indexed for MEDLINE]Related articlesFree article