PubMed

Dynamic insulin sensitivity index: importance in diabetes.

Pillonetto G, Caumo A, Cobelli C.

Am J Physiol Endocrinol Metab. 2009 Nov 17. [Epub ahead of print]PMID: 19920215 [PubMed - as supplied by publisher]Related articles

Retrovirus HTLV-1 gene circuit: a potential oscillator for eukaryotes.

Corradin A, DI Camillo B, Rende F, Ciminale V, Toffolo GM, Cobelli C.

Pac Symp Biocomput. 2010:421-32.PMID: 19908394 [PubMed - in process]Related articlesFree article

Characterizing multisegment foot kinematics during gait in diabetic foot patients.

Sawacha Z, Cristoferi G, Guarneri G, Corazza S, Donà G, Denti P, Facchinetti A, Avogaro A, Cobelli C.

J Neuroeng Rehabil. 2009 Oct 23;6:37.PMID: 19852807 [PubMed - in process]Related articlesFree article

Relationship between fractional pancreatic beta cell area and fasting plasma glucose concentration in monkeys.

Saisho Y, Butler AE, Manesso E, Galasso R, Zhang L, Gurlo T, Toffolo GM, Cobelli C, Kavanagh K, Wagner JD, Butler PC.

Diabetologia. 2009 Oct 22. [Epub ahead of print]PMID: 19847395 [PubMed - as supplied by publisher]Related articles

An On-Line Self-Tuneable Method to Denoise CGM Sensor Data.

Facchinetti A, Sparacino G, Cobelli C.

IEEE Trans Biomed Eng. 2009 Oct 9. [Epub ahead of print]PMID: 19822467 [PubMed - as supplied by publisher]Related articles

Diabetic gait and posture abnormalities: a biomechanical investigation through three dimensional gait analysis.

Sawacha Z, Gabriella G, Cristoferi G, Guiotto A, Avogaro A, Cobelli C.

Clin Biomech (Bristol, Avon). 2009 Nov;24(9):722-8. Epub 2009 Aug 21.PMID: 19699564 [PubMed - in process]Related articles

MINIMAL MODEL ASSESSMENT OF HEPATIC INSULIN EXTRACTION DURING AN ORAL TEST FROM STANDARD INSULIN KINETIC PARAMETERS.

Campioni M, Toffolo GM, Basu R, Rizza RA, Cobelli C.

Am J Physiol Endocrinol Metab. 2009 Aug 11. [Epub ahead of print]PMID: 19671837 [PubMed - as supplied by publisher]Related articles

Dynamics of beta-cell turnover: evidence for beta-cell turnover and regeneration from sources of beta-cells other than beta-cell replication in the HIP rat.

Manesso E, Toffolo GM, Saisho Y, Butler AE, Matveyenko AV, Cobelli C, Butler PC.

Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E323-30. Epub 2009 May 26.PMID: 19470833 [PubMed - indexed for MEDLINE]Related articles

In Silico Preclinical Trials: A Proof of Concept in Closed-Loop Control of Type 1 Diabetes.

Kovatchev BP, Breton M, Man CD, Cobelli C.

J Diabetes Sci Technol. 2009;3(1):44-55.PMID: 19444330 [PubMed]Related articlesFree article

Nonlinear mixed effects to improve glucose minimal model parameter estimation: a simulation study in intensive and sparse sampling.

Denti P, Bertoldo A, Vicini P, Cobelli C.

IEEE Trans Biomed Eng. 2009 Sep;56(9):2156-66. Epub 2009 Apr 17.PMID: 19380266 [PubMed - in process]Related articles

A gene network simulator to assess reverse engineering algorithms.

Di Camillo B, Toffolo G, Cobelli C.

Ann N Y Acad Sci. 2009 Mar;1158:125-42.PMID: 19348638 [PubMed - indexed for MEDLINE]Related articles

Are we optimizing gestational diabetes treatment with glyburide? The pharmacologic basis for better clinical practice.

Hebert MF, Ma X, Naraharisetti SB, Krudys KM, Umans JG, Hankins GD, Caritis SN, Miodovnik M, Mattison DR, Unadkat JD, Kelly EJ, Blough D, Cobelli C, Ahmed MS, Snodgrass WR, Carr DB, Easterling TR, Vicini P; Obstetric-Fetal Pharmacology Research Unit Network.

Clin Pharmacol Ther. 2009 Jun;85(6):607-14. Epub 2009 Mar 18.PMID: 19295505 [PubMed - indexed for MEDLINE]Related articles

Effects of type 2 diabetes on insulin secretion, insulin action, glucose effectiveness, and postprandial glucose metabolism.

Basu A, Dalla Man C, Basu R, Toffolo G, Cobelli C, Rizza RA.

Diabetes Care. 2009 May;32(5):866-72. Epub 2009 Feb 5.PMID: 19196896 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose Minimal Model population analysis: likelihood function profiling via Monte Carlo sampling.

Denti P, Vicini P, Bertoldo A, Cobelli C.

Conf Proc IEEE Eng Med Biol Soc. 2008;2008:4932-5.PMID: 19163823 [PubMed - indexed for MEDLINE]Related articles

Primary defects in beta-cell function further exacerbated by worsening of insulin resistance mark the development of impaired glucose tolerance in obese adolescents.

Cali AM, Man CD, Cobelli C, Dziura J, Seyal A, Shaw M, Allen K, Chen S, Caprio S.

Diabetes Care. 2009 Mar;32(3):456-61. Epub 2008 Dec 23.PMID: 19106382 [PubMed - indexed for MEDLINE]Related articlesFree article

PET parametric imaging improved by global-two-stage method.

Tomasi G, Bertoldo A, Cobelli C.

Ann Biomed Eng. 2009 Feb;37(2):419-27. Epub 2008 Dec 12.PMID: 19082895 [PubMed - indexed for MEDLINE]Related articles

beta-Cell function and insulin sensitivity in adolescents from an OGTT.

Sunehag AL, Man CD, Toffolo G, Haymond MW, Bier DM, Cobelli C.

Obesity (Silver Spring). 2009 Feb;17(2):233-9. Epub 2008 Dec 4.PMID: 19057529 [PubMed - indexed for MEDLINE]Related articles

Development of factors to convert frequency to rate for beta-cell replication and apoptosis quantified by time-lapse video microscopy and immunohistochemistry.

Saisho Y, Manesso E, Gurlo T, Huang CJ, Toffolo GM, Cobelli C, Butler PC.

Am J Physiol Endocrinol Metab. 2009 Jan;296(1):E89-96. Epub 2008 Oct 21.PMID: 18940937 [PubMed - indexed for MEDLINE]Related articles

Dipeptidyl peptidase-4 inhibition by vildagliptin and the effect on insulin secretion and action in response to meal ingestion in type 2 diabetes.

Dalla Man C, Bock G, Giesler PD, Serra DB, Ligueros Saylan M, Foley JE, Camilleri M, Toffolo G, Cobelli C, Rizza RA, Vella A.

Diabetes Care. 2009 Jan;32(1):14-8. Epub 2008 Oct 17.PMID: 18931099 [PubMed - in process]Related articlesFree article

Use of labeled oral minimal model to measure hepatic insulin sensitivity.

Man CD, Toffolo G, Basu R, Rizza RA, Cobelli C.

Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1152-9. Epub 2008 Sep 2.PMID: 18765681 [PubMed - indexed for MEDLINE]Related articlesFree article

Continuous glucose monitoring time series and hypo/hyperglycemia prevention: requirements, methods, open problems.

Sparacino G, Facchinetti A, Maran A, Cobelli C.

Curr Diabetes Rev. 2008 Aug;4(3):181-92. Review.PMID: 18690899 [PubMed - indexed for MEDLINE]Related articles

A subcellular model of glucose-stimulated pancreatic insulin secretion.

Pedersen MG, Corradin A, Toffolo GM, Cobelli C.

Philos Transact A Math Phys Eng Sci. 2008 Oct 13;366(1880):3525-43.PMID: 18653438 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel reference region model reveals increased microglial and reduced vascular binding of 11C-(R)-PK11195 in patients with Alzheimer's disease.

Tomasi G, Edison P, Bertoldo A, Roncaroli F, Singh P, Gerhard A, Cobelli C, Brooks DJ, Turkheimer FE.

J Nucl Med. 2008 Aug;49(8):1249-56. Epub 2008 Jul 16.PMID: 18632810 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluating the Efficacy of Closed-Loop Glucose Regulation via Control-Variability Grid Analysis.

Magni L, Raimondo DM, Man CD, Breton M, Patek S, Nicolao GD, Cobelli C, Kovatchev BP.

J Diabetes Sci Technol. 2008 Jul;2(4):630-5.PMID: 19885239 [PubMed - in process]Free article

Pioglitazone decreases fasting and postprandial endogenous glucose production in proportion to decrease in hepatic triglyceride content.

Ravikumar B, Gerrard J, Dalla Man C, Firbank MJ, Lane A, English PT, Cobelli C, Taylor R.

Diabetes. 2008 Sep;57(9):2288-95. Epub 2008 Jun 5.PMID: 18535187 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired fasting glucose with or without impaired glucose tolerance: progressive or parallel states of prediabetes?

Perreault L, Bergman BC, Playdon MC, Dalla Man C, Cobelli C, Eckel RH.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E428-35. Epub 2008 Jun 3.PMID: 18523123 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on beta-cell function in patients with type 2 diabetes: a model-based approach.

Xu L, Man CD, Charbonnel B, Meninger G, Davies MJ, Williams-Herman D, Cobelli C, Stein PP.

Diabetes Obes Metab. 2008 Dec;10(12):1212-20. Epub 2008 May 12.PMID: 18476982 [PubMed - indexed for MEDLINE]Related articles

Glucose fluxes during OGTT in adolescents assessed by a stable isotope triple tracer method.

Toffolo G, Dalla Man C, Cobelli C, Sunehag AL.

J Pediatr Endocrinol Metab. 2008 Jan;21(1):31-45.PMID: 18404971 [PubMed - indexed for MEDLINE]Related articles

Dexamethasone therapy in preterm infants developing bronchopulmonary dysplasia: effect on pulmonary surfactant disaturated-phosphatidylcholine kinetics.

Cogo PE, Simonato M, Mariatoffolo G, Stefanutti G, Chierici M, Cobelli C, Ori C, Carnielli VP.

Pediatr Res. 2008 Apr;63(4):433-7.PMID: 18356753 [PubMed - indexed for MEDLINE]Related articles

Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes.

Azuma K, Rádiková Z, Mancino J, Toledo FG, Thomas E, Kangani C, Dalla Man C, Cobelli C, Holst JJ, Deacon CF, He Y, Ligueros-Saylan M, Serra D, Foley JE, Kelley DE.

J Clin Endocrinol Metab. 2008 Feb;93(2):459-64. Epub 2007 Nov 27.PMID: 18042650 [PubMed - indexed for MEDLINE]Related articlesFree article

Model predictive control of type 1 diabetes: an in silico trial.

Magni L, Raimondo DM, Bossi L, Man CD, De Nicolao G, Kovatchev B, Cobelli C.

J Diabetes Sci Technol. 2007 Nov;1(6):804-12.PMID: 19885152 [PubMed - in process]Free article

Identification of IVGTT minimal glucose model by nonlinear mixed-effects approaches.

Denti P, Bertoldo A, Vicini P, Cobelli C.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:5049-52.PMID: 17947129 [PubMed - indexed for MEDLINE]Related articles

A model of glucose production during a meal.

Dalla Man C, Toffolo G, Basu R, Rizza RA, Cobelli C.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:5647-50.PMID: 17946713 [PubMed - indexed for MEDLINE]Related articles

Glucose production by deconvolution in intravenous and oral glucose tolerance tests: role of output variable.

Chierici M, Pillonetto G, Toffolo G, Cobelli C.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:5045-8.PMID: 17946671 [PubMed - indexed for MEDLINE]Related articles

Mixed meal simulation model of glucose-insulin system.

Dalla Man C, Rizza RA, Cobelli C.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:307-10.PMID: 17946394 [PubMed - indexed for MEDLINE]Related articles

Reconstructing by deconvolution plasma glucose from continuous glucose monitoring sensor data.

Facchinetti A, Sparacino G, Zanderigo F, Cobelli C.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:55-8.PMID: 17946377 [PubMed - indexed for MEDLINE]Related articles

Meal simulation model of the glucose-insulin system.

Dalla Man C, Rizza RA, Cobelli C.

IEEE Trans Biomed Eng. 2007 Oct;54(10):1740-9.PMID: 17926672 [PubMed - indexed for MEDLINE]Related articles

Reconstruction of glucose in plasma from interstitial fluid continuous glucose monitoring data: role of sensor calibration.

Facchinetti A, Sparacino G, Cobelli C.

J Diabetes Sci Technol. 2007 Sep;1(5):617-23.PMID: 19885129 [PubMed - in process]Free article

Glucose Prediction Algorithms from Continuous Monitoring Data: Assessment of Accuracy via Continuous Glucose Error-Grid Analysis.

Zanderigo F, Sparacino G, Kovatchev B, Cobelli C.

J Diabetes Sci Technol. 2007 Sep 1;1(5):645-651.PMID: 19718282 [PubMed]Related articlesFree article

Glucose concentration can be predicted ahead in time from continuous glucose monitoring sensor time-series.

Sparacino G, Zanderigo F, Corazza S, Maran A, Facchinetti A, Cobelli C.

IEEE Trans Biomed Eng. 2007 May;54(5):931-7.PMID: 17518291 [PubMed - indexed for MEDLINE]Related articles

Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men.

Basu R, Dalla Man C, Campioni M, Basu A, Nair KS, Jensen MD, Khosla S, Klee G, Toffolo G, Cobelli C, Rizza RA.

Diabetes Care. 2007 Aug;30(8):1972-8. Epub 2007 May 11.PMID: 17496236 [PubMed - indexed for MEDLINE]Related articlesFree article

GIM, Simulation Software of Meal Glucose-Insulin Model.

Dalla Man C, Raimondo DM, Rizza RA, Cobelli C.

J Diabetes Sci Technol. 2007 May;1(3):323-30.PMID: 19885087 [PubMed - in process]Free article

Significance analysis of microarray transcript levels in time series experiments.

Di Camillo B, Toffolo G, Nair SK, Greenlund LJ, Cobelli C.

BMC Bioinformatics. 2007 Mar 8;8 Suppl 1:S10.PMID: 17430554 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of nonglucose nutrients on insulin secretion and action in people with pre-diabetes.

Bock G, Dalla Man C, Campioni M, Chittilapilly E, Basu R, Toffolo G, Cobelli C, Rizza R.

Diabetes. 2007 Apr;56(4):1113-9.PMID: 17395750 [PubMed - indexed for MEDLINE]Related articlesFree article

Contribution of hepatic and extrahepatic insulin resistance to the pathogenesis of impaired fasting glucose: role of increased rates of gluconeogenesis.

Bock G, Chittilapilly E, Basu R, Toffolo G, Cobelli C, Chandramouli V, Landau BR, Rizza RA.

Diabetes. 2007 Jun;56(6):1703-11. Epub 2007 Mar 23.PMID: 17384334 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessment of beta-cell function in humans, simultaneously with insulin sensitivity and hepatic extraction, from intravenous and oral glucose tests.

Cobelli C, Toffolo GM, Dalla Man C, Campioni M, Denti P, Caumo A, Butler P, Rizza R.

Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E1-E15. Epub 2007 Mar 6. Review.PMID: 17341552 [PubMed - indexed for MEDLINE]Related articlesFree article

Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women.

Basu R, Dalla Man C, Campioni M, Basu A, Nair KS, Jensen MD, Khosla S, Klee G, Toffolo G, Cobelli C, Rizza RA.

Diabetes. 2007 Mar;56(3):753-66. Erratum in: Diabetes. 2007 May;56(5):1486. PMID: 17327446 [PubMed - indexed for MEDLINE]Related articlesFree article

Surfactant disaturated-phosphatidylcholine kinetics in acute respiratory distress syndrome by stable isotopes and a two compartment model.

Cogo PE, Toffolo GM, Ori C, Vianello A, Chierici M, Gucciardi A, Cobelli C, Baritussio A, Carnielli VP.

Respir Res. 2007 Feb 21;8:13.PMID: 17313681 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of adding sitagliptin, a dipeptidyl peptidase-4 inhibitor, to metformin on 24-h glycaemic control and beta-cell function in patients with type 2 diabetes.

Brazg R, Xu L, Dalla Man C, Cobelli C, Thomas K, Stein PP.

Diabetes Obes Metab. 2007 Mar;9(2):186-93.PMID: 17300594 [PubMed - indexed for MEDLINE]Related articles

A system model of oral glucose absorption: validation on gold standard data.

Dalla Man C, Camilleri M, Cobelli C.

IEEE Trans Biomed Eng. 2006 Dec;53(12 Pt 1):2472-8.PMID: 17153204 [PubMed - indexed for MEDLINE]Related articles