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Cognitive function is disrupted by both hypo- and hyperglycemia in school-aged children with type 1 diabetes: a field study.

Gonder-Frederick LA, Zrebiec JF, Bauchowitz AU, Ritterband LM, Magee JC, Cox DJ, Clarke WL.

Diabetes Care. 2009 Jun;32(6):1001-6. Epub 2009 Mar 26.PMID: 19324943 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical application of emerging sensor technologies in diabetes management: consensus guidelines for continuous glucose monitoring (CGM).

Hirsch IB, Armstrong D, Bergenstal RM, Buckingham B, Childs BP, Clarke WL, Peters A, Wolpert H.

Diabetes Technol Ther. 2008 Aug;10(4):232-44; quiz 245-6. Review.PMID: 18699743 [PubMed - indexed for MEDLINE]Related articles

Evaluating clinical accuracy of continuous glucose monitoring systems: Continuous Glucose-Error Grid Analysis (CG-EGA).

Clarke WL, Anderson S, Kovatchev B.

Curr Diabetes Rev. 2008 Aug;4(3):193-9. Review.PMID: 18690900 [PubMed - indexed for MEDLINE]Related articles

Continuous Glucose Sensors: Continuing Questions about Clinical Accuracy.

Clarke WL, Kovatchev B.

J Diabetes Sci Technol. 2007 Sep;1(5):669-75.PMID: 19885134 [PubMed - in process]Free article

The artificial pancreas: how close are we to closing the loop?

Clarke WL, Kovatchev B.

Pediatr Endocrinol Rev. 2007 Jun;4(4):314-6. No abstract available. PMID: 17643078 [PubMed - indexed for MEDLINE]Related articles

Premature twins of a mother with Graves' disease with discordant thyroid function: a case report.

O'Connor MJ, Paget-Brown AO, Clarke WL.

J Perinatol. 2007 Jun;27(6):388-9.PMID: 17522687 [PubMed - indexed for MEDLINE]Related articles

Modeling of Calibration Effectiveness and Blood-to-Interstitial Glucose Dynamics as Potential Confounders of the Accuracy of Continuous Glucose Sensors during Hyperinsulinemic Clamp.

King C, Anderson SM, Breton M, Clarke WL, Kovatchev BP.

J Diabetes Sci Technol. 2007 May 1;1(3):317-322.PMID: 19756217 [PubMed]Related articlesFree article

Safe at school: a Virginia experience.

Hellems MA, Clarke WL.

Diabetes Care. 2007 Jun;30(6):1396-8. Epub 2007 Mar 10.PMID: 17351272 [PubMed - indexed for MEDLINE]Related articlesFree article

A critical appraisal of the continuous glucose-error grid analysis: response to Wentholt et al.

Clarke WL, Gonder-Frederick L, Cox D, Kovatchev B.

Diabetes Care. 2007 Feb;30(2):449-50; author reply 450-1. No abstract available. Erratum in: Diabetes Care. 2007 Apr;30(4):1035. PMID: 17259537 [PubMed - indexed for MEDLINE]Related articlesFree article

A Model of Self-Treatment Behavior, Glucose Variability, and Hypoglycemia-Associated Autonomic Failure in Type 1 Diabetes.

Breton M, Clarke WL, Farhy L, Kovatchev B.

J Diabetes Sci Technol. 2007;1(3):331-337.PMID: 19606264 [PubMed]Related articlesFree article

Predictors of fear of hypoglycemia in adolescents with type 1 diabetes and their parents.

Gonder-Frederick LA, Fisher CD, Ritterband LM, Cox DJ, Hou L, DasGupta AA, Clarke WL.

Pediatr Diabetes. 2006 Aug;7(4):215-22.PMID: 16911009 [PubMed - indexed for MEDLINE]Related articles

Quantifying temporal glucose variability in diabetes via continuous glucose monitoring: mathematical methods and clinical application.

Kovatchev BP, Clarke WL, Breton M, Brayman K, McCall A.

Diabetes Technol Ther. 2005 Dec;7(6):849-62.PMID: 16386091 [PubMed - indexed for MEDLINE]Related articles

The original Clarke Error Grid Analysis (EGA).

Clarke WL.

Diabetes Technol Ther. 2005 Oct;7(5):776-9. Review. No abstract available. PMID: 16241881 [PubMed - indexed for MEDLINE]Related articles

Evaluating the clinical accuracy of two continuous glucose sensors using continuous glucose-error grid analysis.

Clarke WL, Anderson S, Farhy L, Breton M, Gonder-Frederick L, Cox D, Kovatchev B.

Diabetes Care. 2005 Oct;28(10):2412-7.PMID: 16186272 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationships between hyperglycemia and cognitive performance among adults with type 1 and type 2 diabetes.

Cox DJ, Kovatchev BP, Gonder-Frederick LA, Summers KH, McCall A, Grimm KJ, Clarke WL.

Diabetes Care. 2005 Jan;28(1):71-7.PMID: 15616236 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluating the accuracy of continuous glucose-monitoring sensors: continuous glucose-error grid analysis illustrated by TheraSense Freestyle Navigator data.

Kovatchev BP, Gonder-Frederick LA, Cox DJ, Clarke WL.

Diabetes Care. 2004 Aug;27(8):1922-8.PMID: 15277418 [PubMed - indexed for MEDLINE]Related articlesFree article

Algorithmic evaluation of metabolic control and risk of severe hypoglycemia in type 1 and type 2 diabetes using self-monitoring blood glucose data.

Kovatchev BP, Cox DJ, Kumar A, Gonder-Frederick L, Clarke WL.

Diabetes Technol Ther. 2003;5(5):817-28.PMID: 14633347 [PubMed - indexed for MEDLINE]Related articles

The metabolic demands of driving for drivers with type 1 diabetes mellitus.

Cox DJ, Gonder-Frederick LA, Kovatchev BP, Clarke WL.

Diabetes Metab Res Rev. 2002 Sep-Oct;18(5):381-5.PMID: 12397580 [PubMed - indexed for MEDLINE]Related articles

Methods for quantifying self-monitoring blood glucose profiles exemplified by an examination of blood glucose patterns in patients with type 1 and type 2 diabetes.

Kovatchev BP, Cox DJ, Gonder-Frederick L, Clarke WL.

Diabetes Technol Ther. 2002;4(3):295-303.PMID: 12165168 [PubMed - indexed for MEDLINE]Related articles

Self-treatment of hypoglycemia while driving.

Cox DJ, Gonder-Frederick LA, Kovatchev BP, Clarke WL.

Diabetes Res Clin Pract. 2001 Oct;54(1):17-26.PMID: 11532326 [PubMed - indexed for MEDLINE]Related articles

The effects of pubertal status and glycemic control on the growth hormone-IGF-I axis in boys with insulin-dependent diabetes mellitus.

Clark PA, Clarke WL, Pedadda S, Reiss A, Langlois C, Nieves-Rivera F, Rogol AD.

J Pediatr Endocrinol Metab. 1998;11(3):427-35.PMID: 11517959 [PubMed - indexed for MEDLINE]Related articles

Episodes of severe hypoglycemia in type 1 diabetes are preceded and followed within 48 hours by measurable disturbances in blood glucose.

Kovatchev BP, Cox DJ, Farhy LS, Straume M, Gonder-Frederick L, Clarke WL.

J Clin Endocrinol Metab. 2000 Nov;85(11):4287-92.PMID: 11095469 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired insulin secretion and increased insulin sensitivity in familial maturity-onset diabetes of the young 4 (insulin promoter factor 1 gene).

Clocquet AR, Egan JM, Stoffers DA, Muller DC, Wideman L, Chin GA, Clarke WL, Hanks JB, Habener JF, Elahi D.

Diabetes. 2000 Nov;49(11):1856-64.PMID: 11078452 [PubMed - indexed for MEDLINE]Related articlesFree article

Progressive hypoglycemia's impact on driving simulation performance. Occurrence, awareness and correction.

Cox DJ, Gonder-Frederick LA, Kovatchev BP, Julian DM, Clarke WL.

Diabetes Care. 2000 Feb;23(2):163-70.PMID: 10868825 [PubMed - indexed for MEDLINE]Related articlesFree article

Biopsychobehavioral model of severe hypoglycemia. II. Understanding the risk of severe hypoglycemia.

Cox DJ, Gonder-Frederick LA, Kovatchev BP, Young-Hyman DL, Donner TW, Julian DM, Clarke WL.

Diabetes Care. 1999 Dec;22(12):2018-25.PMID: 10587836 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoglycemia and the decision to drive a motor vehicle by persons with diabetes.

Clarke WL, Cox DJ, Gonder-Frederick LA, Kovatchev B.

JAMA. 1999 Aug 25;282(8):750-4.PMID: 10463710 [PubMed - indexed for MEDLINE]Related articlesFree article

Biopsychobehavioral model of risk of severe hypoglycemia. Self-management behaviors.

Clarke WL, Cox DJ, Gonder-Frederick L, Julian D, Kovatchev B, Young-Hyman D.

Diabetes Care. 1999 Apr;22(4):580-4.PMID: 10189535 [PubMed - indexed for MEDLINE]Related articlesFree article

Maternal fear of hypoglycemia in their children with insulin dependent diabetes mellitus.

Clarke WL, Gonder-Frederick A, Snyder AL, Cox DJ.

J Pediatr Endocrinol Metab. 1998 Mar;11 Suppl 1:189-94.PMID: 9642659 [PubMed - indexed for MEDLINE]Related articles

Early-onset type-II diabetes mellitus (MODY4) linked to IPF1.

Stoffers DA, Ferrer J, Clarke WL, Habener JF.

Nat Genet. 1997 Oct;17(2):138-9. No abstract available. PMID: 9326926 [PubMed - indexed for MEDLINE]Related articles

Understanding error grid analysis.

Cox DJ, Gonder-Frederick LA, Kovatchev BP, Julian DM, Clarke WL.

Diabetes Care. 1997 Jun;20(6):911-2. Review. No abstract available. PMID: 9167098 [PubMed - indexed for MEDLINE]Related articles

The Emotional, Social, and Behavioral Implications of Insulin-Induced Hypoglycemia.

Gonder-Frederick LA, Clarke WL, Cox DJ.

Semin Clin Neuropsychiatry. 1997 Jan;2(1):57-65.PMID: 10320443 [PubMed - as supplied by publisher]Related articles

The relationship between nonroutine use of insulin, food, and exercise and the occurrence of hypoglycemia in adults with IDDM and varying degrees of hypoglycemic awareness and metabolic control.

Clarke WL, Cox DJ, Gonder-Frederick LA, Julian D, Schlundt D, Polonsky W.

Diabetes Educ. 1997 Jan-Feb;23(1):55-8.PMID: 9052056 [PubMed - indexed for MEDLINE]Related articles

Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence.

Stoffers DA, Zinkin NT, Stanojevic V, Clarke WL, Habener JF.

Nat Genet. 1997 Jan;15(1):106-10.PMID: 8988180 [PubMed - indexed for MEDLINE]Related articles

Psychometric properties and normative data for the parent version of the diabetes independence survey.

Wysocki T, Meinhold PM, Taylor A, Hough BS, Barnard MU, Clarke WL, Bellando BJ, Bourgeois MJ.

Diabetes Educ. 1996 Nov-Dec;22(6):587-91.PMID: 8970288 [PubMed - indexed for MEDLINE]Related articles

Sex differences in plasma glucose thresholds for counterregulatory hormone release and hypoglycemia symptom perception.

Cox DJ, Gonder-Frederick LA, Julian DM, Clarke WL.

Diabetes Care. 1996 Mar;19(3):269-70. No abstract available. PMID: 8742576 [PubMed - indexed for MEDLINE]Related articles

The frequency of severe hypoglycaemia in children with insulin-dependent diabetes mellitus.

Clarke WL, Gonder-Frederick L, Cox DJ.

Horm Res. 1996;45 Suppl 1:48-52. Review.PMID: 8805031 [PubMed - indexed for MEDLINE]Related articles

Testotoxicosis. An unusual presentation and novel gene mutation.

Clark PA, Clarke WL.

Clin Pediatr (Phila). 1995 May;34(5):271-4. No abstract available. PMID: 7628171 [PubMed - indexed for MEDLINE]Related articles

Reduced awareness of hypoglycemia in adults with IDDM. A prospective study of hypoglycemic frequency and associated symptoms.

Clarke WL, Cox DJ, Gonder-Frederick LA, Julian D, Schlundt D, Polonsky W.

Diabetes Care. 1995 Apr;18(4):517-22.PMID: 7497862 [PubMed - indexed for MEDLINE]Related articles

The Diabetes Control and Complications Trial: new challenges for the school nurse.

Snyder AL, Clarke WL.

J Sch Nurs. 1995 Feb;11(1):22-5.PMID: 7767044 [PubMed - indexed for MEDLINE]Related articles

Frequency of severe hypoglycemia in insulin-dependent diabetes mellitus can be predicted from self-monitoring blood glucose data.

Cox DJ, Kovatchev BP, Julian DM, Gonder-Frederick LA, Polonsky WH, Schlundt DG, Clarke WL.

J Clin Endocrinol Metab. 1994 Dec;79(6):1659-62.PMID: 7989471 [PubMed - indexed for MEDLINE]Related articles

Individual differences in neurobehavioral disruption during mild and moderate hypoglycemia in adults with IDDM.

Gonder-Frederick LA, Cox DJ, Driesen NR, Ryan CM, Clarke WL.

Diabetes. 1994 Dec;43(12):1407-12.PMID: 7958491 [PubMed - indexed for MEDLINE]Related articles

Reliability of driving performance during moderate hypoglycemia in adults with IDDM.

Quillian WC, Cox DJ, Gonder-Frederick LA, Driesen NR, Clarke WL.

Diabetes Care. 1994 Nov;17(11):1367-8. No abstract available. PMID: 7821187 [PubMed - indexed for MEDLINE]Related articles

The Diabetes Control and Complications Trial: new challenges for the primary physician.

Clarke WL.

Va Med Q. 1994 Summer;121(3):185-8. No abstract available. PMID: 8061070 [PubMed - indexed for MEDLINE]Related articles

Growth and the child with diabetes mellitus.

Clarke WL, Vance ML, Rogol AD.

Diabetes Care. 1993 Dec;16 Suppl 3:101-6. Review. No abstract available. PMID: 8299467 [PubMed - indexed for MEDLINE]Related articles

Disruptive effects of acute hypoglycemia on speed of cognitive and motor performance.

Cox DJ, Gonder-Frederick LA, Schroeder DB, Cryer PE, Clarke WL.

Diabetes Care. 1993 Oct;16(10):1391-3.PMID: 8269799 [PubMed - indexed for MEDLINE]Related articles

Alterations in growth hormone secretion and clearance in adolescent boys with insulin-dependent diabetes mellitus.

Nieves-Rivera F, Rogol AD, Veldhuis JD, Branscom DK, Martha PM Jr, Clarke WL.

J Clin Endocrinol Metab. 1993 Sep;77(3):638-43.PMID: 8370685 [PubMed - indexed for MEDLINE]Related articles

Permanent neonatal diabetes mellitus and pancreatic exocrine insufficiency resulting from congenital pancreatic agenesis.

Wright NM, Metzger DL, Borowitz SM, Clarke WL.

Am J Dis Child. 1993 Jun;147(6):607-9. No abstract available. PMID: 8506821 [PubMed - indexed for MEDLINE]Related articles

Perceived symptoms in the recognition of hypoglycemia.

Cox DJ, Gonder-Frederick L, Antoun B, Cryer PE, Clarke WL.

Diabetes Care. 1993 Feb;16(2):519-27. Review.PMID: 8432227 [PubMed - indexed for MEDLINE]Related articles

Parental and professional estimates of self-care independence of children and adolescents with IDDM.

Wysocki T, Meinhold PA, Abrams KC, Barnard MU, Clarke WL, Bellando BJ, Bourgeois MJ.

Diabetes Care. 1992 Jan;15(1):43-52.PMID: 1737541 [PubMed - indexed for MEDLINE]Related articles

Accuracy of blood glucose estimation by children with IDDM and their parents.

Gonder-Frederick LA, Snyder AL, Clarke WL.

Diabetes Care. 1991 Jul;14(7):565-70.PMID: 1914796 [PubMed - indexed for MEDLINE]Related articles