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    Results: 1 to 50 of 181

    1.

    The 26S proteasome - from basic mechanisms to drug targeting.

    Navon A, Ciechanover A.

    J Biol Chem. 2009 Oct 7. [Epub ahead of print]PMID: 19812037 [PubMed - as supplied by publisher]Related articlesFree article

    2.

    ABIN-1 negatively regulates NF-kappaB by inhibiting processing of the p105 precursor.

    Cohen S, Ciechanover A, Kravtsova-Ivantsiv Y, Lapid D, Lahav-Baratz S.

    Biochem Biophys Res Commun. 2009 Nov 13;389(2):205-10. Epub 2009 Aug 18.PMID: 19695220 [PubMed - indexed for MEDLINE]Related articles

    3.

    Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation.

    Shabek N, Herman-Bachinsky Y, Ciechanover A.

    Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):11907-12. Epub 2009 Jul 6.PMID: 19581590 [PubMed - indexed for MEDLINE]Related articles

    4.

    The 2008 Lindau Nobel Laureate Meeting: Aaron Ciechanover, Chemistry 2004.

    Ciechanover A.

    J Vis Exp. 2009 Jul 1;(29). pii: 1559. doi: 10.3791/1559.PMID: 19571788 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Interview with Aaron Ciechanover.

    Ciechanover A.

    Biochem Biophys Res Commun. 2009 Sep 11;387(1):11-2. Epub 2009 Jun 21. No abstract available. PMID: 19549505 [PubMed - indexed for MEDLINE]Related articles

    6.

    Tracing the history of the ubiquitin proteolytic system: the pioneering article.

    Ciechanover A.

    Biochem Biophys Res Commun. 2009 Sep 11;387(1):1-10. Epub 2009 Jun 17.PMID: 19539608 [PubMed - indexed for MEDLINE]Related articles

    7.

    Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

    Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Castedo M, Cidlowski JA, Ciechanover A, Cohen GM, De Laurenzi V, De Maria R, Deshmukh M, Dynlacht BD, El-Deiry WS, Flavell RA, Fulda S, Garrido C, Golstein P, Gougeon ML, Green DR, Gronemeyer H, Hajnóczky G, Hardwick JM, Hengartner MO, Ichijo H, Jäättelä M, Kepp O, Kimchi A, Klionsky DJ, Knight RA, Kornbluth S, Kumar S, Levine B, Lipton SA, Lugli E, Madeo F, Malomi W, Marine JC, Martin SJ, Medema JP, Mehlen P, Melino G, Moll UM, Morselli E, Nagata S, Nicholson DW, Nicotera P, Nuñez G, Oren M, Penninger J, Pervaiz S, Peter ME, Piacentini M, Prehn JH, Puthalakath H, Rabinovich GA, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Scorrano L, Simon HU, Steller H, Tschopp J, Tsujimoto Y, Vandenabeele P, Vitale I, Vousden KH, Youle RJ, Yuan J, Zhivotovsky B, Kroemer G.

    Cell Death Differ. 2009 Aug;16(8):1093-107. Epub 2009 Apr 17. Review.PMID: 19373242 [PubMed - indexed for MEDLINE]Related articles

    8.

    Ubiquitination participates in the lysosomal degradation of Na,K-ATPase in steady-state conditions.

    Lecuona E, Sun H, Vohwinkel C, Ciechanover A, Sznajder JI.

    Am J Respir Cell Mol Biol. 2009 Dec;41(6):671-9. Epub 2009 Mar 13.PMID: 19286978 [PubMed - in process]Related articles

    9.

    Modification by single ubiquitin moieties rather than polyubiquitination is sufficient for proteasomal processing of the p105 NF-kappaB precursor.

    Kravtsova-Ivantsiv Y, Cohen S, Ciechanover A.

    Mol Cell. 2009 Feb 27;33(4):496-504.PMID: 19250910 [PubMed - indexed for MEDLINE]Related articles

    10.

    The N-terminal domain of MyoD is necessary and sufficient for its nuclear localization-dependent degradation by the ubiquitin system.

    Sadeh R, Breitschopf K, Bercovich B, Zoabi M, Kravtsova-Ivantsiv Y, Kornitzer D, Schwartz A, Ciechanover A.

    Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15690-5. Epub 2008 Oct 3.PMID: 18836078 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology.

    Schwartz AL, Ciechanover A.

    Annu Rev Pharmacol Toxicol. 2009;49:73-96. Review.PMID: 18834306 [PubMed - indexed for MEDLINE]Related articles

    12.

    Ubiquitin-proteasome-mediated degradation of keratin intermediate filaments in mechanically stimulated A549 cells.

    Jaitovich A, Mehta S, Na N, Ciechanover A, Goldman RD, Ridge KM.

    J Biol Chem. 2008 Sep 12;283(37):25348-55. Epub 2008 Jul 10.PMID: 18617517 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    The HECT family of E3 ubiquitin ligases: multiple players in cancer development.

    Bernassola F, Karin M, Ciechanover A, Melino G.

    Cancer Cell. 2008 Jul 8;14(1):10-21. Review.PMID: 18598940 [PubMed - indexed for MEDLINE]Related articles

    14.

    Itch: a HECT-type E3 ligase regulating immunity, skin and cancer.

    Melino G, Gallagher E, Aqeilan RI, Knight R, Peschiaroli A, Rossi M, Scialpi F, Malatesta M, Zocchi L, Browne G, Ciechanover A, Bernassola F.

    Cell Death Differ. 2008 Jul;15(7):1103-12. Review.PMID: 18552861 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    In vivo interactions of MyoD, Id1, and E2A proteins determined by acceptor photobleaching fluorescence resonance energy transfer.

    Lingbeck JM, Trausch-Azar JS, Ciechanover A, Schwartz AL.

    FASEB J. 2008 Jun;22(6):1694-701. Epub 2008 Jan 15.PMID: 18198216 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Hypoxia-mediated Na-K-ATPase degradation requires von Hippel Lindau protein.

    Zhou G, Dada LA, Chandel NS, Iwai K, Lecuona E, Ciechanover A, Sznajder JI.

    FASEB J. 2008 May;22(5):1335-42. Epub 2007 Dec 11.PMID: 18073334 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Ubiquitin is degraded by the ubiquitin system as a monomer and as part of its conjugated target.

    Shabek N, Iwai K, Ciechanover A.

    Biochem Biophys Res Commun. 2007 Nov 16;363(2):425-31. Epub 2007 Sep 10.PMID: 17870054 [PubMed - indexed for MEDLINE]Related articles

    19.

    Phosphorylation and ubiquitination are necessary for Na,K-ATPase endocytosis during hypoxia.

    Dada LA, Welch LC, Zhou G, Ben-Saadon R, Ciechanover A, Sznajder JI.

    Cell Signal. 2007 Sep;19(9):1893-8. Epub 2007 May 5.PMID: 17532187 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Regulation of the Drosophila ubiquitin ligase DIAP1 is mediated via several distinct ubiquitin system pathways.

    Herman-Bachinsky Y, Ryoo HD, Ciechanover A, Gonen H.

    Cell Death Differ. 2007 Apr;14(4):861-71. Epub 2007 Jan 5.PMID: 17205079 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    The polycomb protein Ring1B generates self atypical mixed ubiquitin chains required for its in vitro histone H2A ligase activity.

    Ben-Saadon R, Zaaroor D, Ziv T, Ciechanover A.

    Mol Cell. 2006 Dec 8;24(5):701-11.PMID: 17157253 [PubMed - indexed for MEDLINE]Related articles

    22.

    Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting.

    Ciechanover A.

    Hematology Am Soc Hematol Educ Program. 2006:1-12, 505-6. Review.PMID: 17124032 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    Narrative review: protein degradation and human diseases: the ubiquitin connection.

    Reinstein E, Ciechanover A.

    Ann Intern Med. 2006 Nov 7;145(9):676-84. Review.PMID: 17088581 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    E2A protein degradation by the ubiquitin-proteasome system is stage-dependent during muscle differentiation.

    Sun L, Trausch-Azar JS, Ciechanover A, Schwartz AL.

    Oncogene. 2007 Jan 18;26(3):441-8. Epub 2006 Aug 7.PMID: 16909127 [PubMed - indexed for MEDLINE]Related articles

    25.

    Nobel round-table discussion #2: conflicts of interest, scientific misconduct, fair sharing, and intellectual property in an interdisciplinary/inter-institutional consortium.

    Ehringhaus SH, Ciechanover AJ, Hulse RA, Pascal CB, Goodman SR.

    Exp Biol Med (Maywood). 2006 Jul;231(7):1240-54. No abstract available. PMID: 16816129 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    Nobel round-table discussion #1: the future of interdisciplinary research and training.

    Goodman SR, Ciechanover AJ, Hulse RA, Feng da H, Fluckiger S.

    Exp Biol Med (Maywood). 2006 Jul;231(7):1225-39. No abstract available. PMID: 16816128 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.
    28.

    Two distinct ubiquitin-dependent mechanisms are involved in NF-kappaB p105 proteolysis.

    Cohen S, Lahav-Baratz S, Ciechanover A.

    Biochem Biophys Res Commun. 2006 Jun 23;345(1):7-13. Epub 2006 Apr 24.PMID: 16678126 [PubMed - indexed for MEDLINE]Related articles

    29.

    Hypoxia-mediated degradation of Na,K-ATPase via mitochondrial reactive oxygen species and the ubiquitin-conjugating system.

    Comellas AP, Dada LA, Lecuona E, Pesce LM, Chandel NS, Quesada N, Budinger GR, Strous GJ, Ciechanover A, Sznajder JI.

    Circ Res. 2006 May 26;98(10):1314-22. Epub 2006 Apr 13.PMID: 16614303 [PubMed - indexed for MEDLINE]Related articlesFree article

    30.

    The ubiquitin proteolytic system: from an idea to the patient bed.

    Ciechanover A.

    Proc Am Thorac Soc. 2006;3(1):21-31. Review. No abstract available. PMID: 16493148 [PubMed - indexed for MEDLINE]Related articlesFree article

    31.

    The ubiquitin proteolytic system: from a vague idea, through basic mechanisms, and onto human diseases and drug targeting.

    Ciechanover A.

    Neurology. 2006 Jan 24;66(2 Suppl 1):S7-19. Review. No abstract available. PMID: 16432150 [PubMed - indexed for MEDLINE]Related articles

    34.

    Early work on the ubiquitin proteasome system, an interview with Aaron Ciechanover. Interview by CDD.

    Ciechanover A.

    Cell Death Differ. 2005 Sep;12(9):1167-77. No abstract available. PMID: 16094393 [PubMed - indexed for MEDLINE]Related articlesFree article

    35.

    The ubiquitin-proteasome system--micro target for macro intervention?

    Herrmann J, Ciechanover A, Lerman LO, Lerman A.

    Int J Cardiovasc Intervent. 2005;7(1):5-13. Review.PMID: 16019609 [PubMed - indexed for MEDLINE]Related articles

    36.

    E12 and E47 modulate cellular localization and proteasome-mediated degradation of MyoD and Id1.

    Lingbeck JM, Trausch-Azar JS, Ciechanover A, Schwartz AL.

    Oncogene. 2005 Sep 22;24(42):6376-84.PMID: 16007194 [PubMed - indexed for MEDLINE]Related articles

    37.

    N-terminal ubiquitination.

    Ciechanover A.

    Methods Mol Biol. 2005;301:255-70.PMID: 15917637 [PubMed - indexed for MEDLINE]Related articles

    38.

    Ubiquitin-proteasome-mediated degradation, intracellular localization, and protein synthesis of MyoD and Id1 during muscle differentiation.

    Sun L, Trausch-Azar JS, Ciechanover A, Schwartz AL.

    J Biol Chem. 2005 Jul 15;280(28):26448-56. Epub 2005 May 11.PMID: 15888449 [PubMed - indexed for MEDLINE]Related articlesFree article

    39.

    Regulation of the proapoptotic ARTS protein by ubiquitin-mediated degradation.

    Lotan R, Rotem A, Gonen H, Finberg JP, Kemeny S, Steller H, Ciechanover A, Larisch S.

    J Biol Chem. 2005 Jul 8;280(27):25802-10. Epub 2005 Apr 18.PMID: 15837787 [PubMed - indexed for MEDLINE]Related articlesFree article

    40.

    Proteolysis: from the lysosome to ubiquitin and the proteasome.

    Ciechanover A.

    Nat Rev Mol Cell Biol. 2005 Jan;6(1):79-87.PMID: 15688069 [PubMed - indexed for MEDLINE]Related articles

    41.

    The ubiquitin system: pathogenesis of human diseases and drug targeting.

    Ciechanover A, Schwartz AL.

    Biochim Biophys Acta. 2004 Nov 29;1695(1-3):3-17. Review.PMID: 15571805 [PubMed - indexed for MEDLINE]Related articles

    42.
    43.

    The ubiquitin system: from basic mechanisms to the patient bed.

    Ciechanover A, Iwai K.

    IUBMB Life. 2004 Apr;56(4):193-201. Review.PMID: 15230346 [PubMed - indexed for MEDLINE]Related articles

    44.

    Decreased level of the cell cycle regulator p27 and increased level of its ubiquitin ligase Skp2 in endometrial carcinoma but not in normal secretory or in hyperstimulated endometrium.

    Lahav-Baratz S, Ben-Izhak O, Sabo E, Ben-Eliezer S, Lavie O, Ishai D, Ciechanover A, Dirnfeld M.

    Mol Hum Reprod. 2004 Aug;10(8):567-72. Epub 2004 Jun 25.PMID: 15220466 [PubMed - indexed for MEDLINE]Related articlesFree article

    45.

    Ubiquitin-Proteasome-mediated degradation of Id1 is modulated by MyoD.

    Trausch-Azar JS, Lingbeck J, Ciechanover A, Schwartz AL.

    J Biol Chem. 2004 Jul 30;279(31):32614-9. Epub 2004 May 25.PMID: 15163661 [PubMed - indexed for MEDLINE]Related articlesFree article

    46.

    Caspase activation inhibits proteasome function during apoptosis.

    Sun XM, Butterworth M, MacFarlane M, Dubiel W, Ciechanover A, Cohen GM.

    Mol Cell. 2004 Apr 9;14(1):81-93.PMID: 15068805 [PubMed - indexed for MEDLINE]Related articles

    47.

    Ubiquitin as a central cellular regulator.

    Finley D, Ciechanover A, Varshavsky A.

    Cell. 2004 Jan 23;116(2 Suppl):S29-32, 2 p following S32. No abstract available. PMID: 15055578 [PubMed - indexed for MEDLINE]Related articles

    48.

    N-terminal ubiquitination: more protein substrates join in.

    Ciechanover A, Ben-Saadon R.

    Trends Cell Biol. 2004 Mar;14(3):103-6. Review.PMID: 15055197 [PubMed - indexed for MEDLINE]Related articles

    49.

    Degradation of the Id2 developmental regulator: targeting via N-terminal ubiquitination.

    Fajerman I, Schwartz AL, Ciechanover A.

    Biochem Biophys Res Commun. 2004 Feb 6;314(2):505-12.PMID: 14733935 [PubMed - indexed for MEDLINE]Related articles

    50.

    The ubiquitin-proteasome system in cardiovascular diseases-a hypothesis extended.

    Herrmann J, Ciechanover A, Lerman LO, Lerman A.

    Cardiovasc Res. 2004 Jan 1;61(1):11-21. Review. Erratum in: Cardiovasc Res. 2004 Sep 1;63(4):756. PMID: 14732197 [PubMed - indexed for MEDLINE]Related articlesFree article

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