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Selective regulation of cellular and secreted multimeric adiponectin by antidiabetic therapies in humans.

Phillips SA, Kung J, Ciaraldi TP, Choe C, Christiansen L, Mudaliar S, Henry RR.

Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E767-73. Epub 2009 Jul 21.PMID: 19622782 [PubMed - indexed for MEDLINE]Related articles

GSK-3beta and control of glucose metabolism and insulin action in human skeletal muscle.

Ciaraldi TP, Carter L, Mudaliar S, Henry RR.

Mol Cell Endocrinol. 2009 Jun 6. [Epub ahead of print]PMID: 19505532 [PubMed - as supplied by publisher]Related articles

Myotoxic reactions to lipid-lowering therapy are associated with altered oxidation of fatty acids.

Phillips PS, Ciaraldi TP, Kim DL, Verity MA, Wolfson T, Henry RR; Scripps Mercy Clinical Research Center.

Endocrine. 2009 Feb;35(1):38-46. Epub 2008 Dec 3.PMID: 19051066 [PubMed - indexed for MEDLINE]Related articles

Response of adiponectin and its receptors to changes in metabolic state after gastric bypass surgery: dissociation between adipose tissue expression and circulating levels.

Savu MK, Phillips SA, Oh DK, Park K, Gerlan C, Ciaraldi TP, Henry RR.

Surg Obes Relat Dis. 2009 Mar-Apr;5(2):172-80. Epub 2008 Aug 22.PMID: 18996753 [PubMed - indexed for MEDLINE]Related articles

Metabolic and hormonal changes induced by pioglitazone in polycystic ovary syndrome: a randomized, placebo-controlled clinical trial.

Aroda VR, Ciaraldi TP, Burke P, Mudaliar S, Clopton P, Phillips S, Chang RJ, Henry RR.

J Clin Endocrinol Metab. 2009 Feb;94(2):469-76. Epub 2008 Nov 4.PMID: 18984667 [PubMed - indexed for MEDLINE]Related articles

Polycystic ovary syndrome is associated with tissue-specific differences in insulin resistance.

Ciaraldi TP, Aroda V, Mudaliar S, Chang RJ, Henry RR.

J Clin Endocrinol Metab. 2009 Jan;94(1):157-63. Epub 2008 Oct 14.PMID: 18854391 [PubMed - indexed for MEDLINE]Related articles

Adiponectin secretion and response to pioglitazone is depot dependent in cultured human adipose tissue.

Phillips SA, Ciaraldi TP, Oh DK, Savu MK, Henry RR.

Am J Physiol Endocrinol Metab. 2008 Oct;295(4):E842-50. Epub 2008 Jul 29.PMID: 18664597 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of myotonic dystrophy protein kinase (DMPK) in glucose homeostasis and muscle insulin action.

Llagostera E, Catalucci D, Marti L, Liesa M, Camps M, Ciaraldi TP, Kondo R, Reddy S, Dillmann WH, Palacin M, Zorzano A, Ruiz-Lozano P, Gomis R, Kaliman P.

PLoS One. 2007 Nov 7;2(11):e1134.PMID: 17987120 [PubMed - indexed for MEDLINE]Related articlesFree article

Circulating and cellular adiponectin in polycystic ovary syndrome: relationship to glucose tolerance and insulin action.

Aroda V, Ciaraldi TP, Chang SA, Dahan MH, Chang RJ, Henry RR.

Fertil Steril. 2008 May;89(5):1200-8. Epub 2007 Aug 13.PMID: 17706206 [PubMed - indexed for MEDLINE]Related articles

Role of glycogen synthase kinase-3 alpha in insulin action in cultured human skeletal muscle cells.

Ciaraldi TP, Nikoulina SE, Bandukwala RA, Carter L, Henry RR.

Endocrinology. 2007 Sep;148(9):4393-9. Epub 2007 Jun 14.PMID: 17569761 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced adiponectin multimer ratio and skeletal muscle adiponectin receptor expression following exercise training and diet in older insulin-resistant adults.

O'Leary VB, Jorett AE, Marchetti CM, Gonzalez F, Phillips SA, Ciaraldi TP, Kirwan JP.

Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E421-7. Epub 2007 May 8.PMID: 17488807 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects.

Graham TE, Yang Q, Blüher M, Hammarstedt A, Ciaraldi TP, Henry RR, Wason CJ, Oberbach A, Jansson PA, Smith U, Kahn BB.

N Engl J Med. 2006 Jun 15;354(24):2552-63.PMID: 16775236 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific expression and regulation of GSK-3 in human skeletal muscle and adipose tissue.

Ciaraldi TP, Oh DK, Christiansen L, Nikoulina SE, Kong AP, Baxi S, Mudaliar S, Henry RR.

Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E891-8. Epub 2006 Jun 6.PMID: 16757548 [PubMed - indexed for MEDLINE]Related articlesFree article

Improvements in insulin resistance with weight loss, in contrast to rosiglitazone, are not associated with changes in plasma adiponectin or adiponectin multimeric complexes.

Abbasi F, Chang SA, Chu JW, Ciaraldi TP, Lamendola C, McLaughlin T, Reaven GM, Reaven PD.

Am J Physiol Regul Integr Comp Physiol. 2006 Jan;290(1):R139-44.PMID: 16352858 [PubMed - indexed for MEDLINE]Related articles

Adipocyte differentiation-related protein in human skeletal muscle: relationship to insulin sensitivity.

Phillips SA, Choe CC, Ciaraldi TP, Greenberg AS, Kong AP, Baxi SC, Christiansen L, Mudaliar SR, Henry RR.

Obes Res. 2005 Aug;13(8):1321-9.PMID: 16129713 [PubMed - indexed for MEDLINE]Related articles

Effects of the rapid-acting insulin analog glulisine on cultured human skeletal muscle cells: comparisons with insulin and insulin-like growth factor I.

Ciaraldi TP, Phillips SA, Carter L, Aroda V, Mudaliar S, Henry RR.

J Clin Endocrinol Metab. 2005 Oct;90(10):5551-8. Epub 2005 Jul 19.PMID: 16030168 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired fatty acid metabolism in type 2 diabetic skeletal muscle cells is reversed by PPARgamma agonists.

Cha BS, Ciaraldi TP, Park KS, Carter L, Mudaliar SR, Henry RR.

Am J Physiol Endocrinol Metab. 2005 Jul;289(1):E151-9. Epub 2005 Feb 22.PMID: 15727952 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal muscle GLUT1 transporter protein expression and basal leg glucose uptake are reduced in type 2 diabetes.

Ciaraldi TP, Mudaliar S, Barzin A, Macievic JA, Edelman SV, Park KS, Henry RR.

J Clin Endocrinol Metab. 2005 Jan;90(1):352-8. Epub 2004 Oct 13.PMID: 15483099 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced insulin signaling via Shc in human breast cancer.

Finlayson CA, Chappell J, Leitner JW, Goalstone ML, Garrity M, Nawaz S, Ciaraldi TP, Draznin B.

Metabolism. 2003 Dec;52(12):1606-11.PMID: 14669164 [PubMed - indexed for MEDLINE]Related articles

Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction.

Kim YB, Kotani K, Ciaraldi TP, Henry RR, Kahn BB.

Diabetes. 2003 Aug;52(8):1935-42.PMID: 12882908 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of skeletal muscle morphology in type 2 diabetic subjects by troglitazone and metformin: relationship to glucose disposal.

Mathieu-Costello O, Kong A, Ciaraldi TP, Cui L, Ju Y, Chu N, Kim D, Mudaliar S, Henry RR.

Metabolism. 2003 May;52(5):540-6.PMID: 12759881 [PubMed - indexed for MEDLINE]Related articles

Thiazolidinediones upregulate impaired fatty acid uptake in skeletal muscle of type 2 diabetic subjects.

Wilmsen HM, Ciaraldi TP, Carter L, Reehman N, Mudaliar SR, Henry RR.

Am J Physiol Endocrinol Metab. 2003 Aug;285(2):E354-62. Epub 2003 Apr 15.PMID: 12700163 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of circulating and adipose tissue adiponectin levels by antidiabetic therapy.

Phillips SA, Ciaraldi TP, Kong AP, Bandukwala R, Aroda V, Carter L, Baxi S, Mudaliar SR, Henry RR.

Diabetes. 2003 Mar;52(3):667-74.PMID: 12606507 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin and insulin-like growth factor-1 action on human skeletal muscle: preferential effects of insulin-like growth factor-1 in type 2 diabetic subjects.

Ciaraldi TP, Carter L, Rehman N, Mohideen P, Mudaliar S, Henry RR.

Metabolism. 2002 Sep;51(9):1171-9.PMID: 12200763 [PubMed - indexed for MEDLINE]Related articles

Intravenous glargine and regular insulin have similar effects on endogenous glucose output and peripheral activation/deactivation kinetic profiles.

Mudaliar S, Mohideen P, Deutsch R, Ciaraldi TP, Armstrong D, Kim B, Sha X, Henry RR.

Diabetes Care. 2002 Sep;25(9):1597-602.PMID: 12196433 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle.

Nikoulina SE, Ciaraldi TP, Mudaliar S, Carter L, Johnson K, Henry RR.

Diabetes. 2002 Jul;51(7):2190-8.PMID: 12086949 [PubMed - indexed for MEDLINE]Related articlesFree article

Free fatty acid metabolism in human skeletal muscle is regulated by PPARgamma and RXR agonists.

Ciaraldi TP, Cha BS, Park KS, Carter L, Mudaliar SR, Henry RR.

Ann N Y Acad Sci. 2002 Jun;967:66-70. Review.PMID: 12079836 [PubMed - indexed for MEDLINE]Related articles

Role of glycogen synthase kinase-3 in skeletal muscle insulin resistance in Type 2 diabetes.

Ciaraldi TP, Nikoulina SE, Henry RR.

J Diabetes Complications. 2002 Jan-Feb;16(1):69-71. Review. No abstract available. PMID: 11872371 [PubMed - indexed for MEDLINE]Related articles

Troglitazone but not metformin restores insulin-stimulated phosphoinositide 3-kinase activity and increases p110beta protein levels in skeletal muscle of type 2 diabetic subjects.

Kim YB, Ciaraldi TP, Kong A, Kim D, Chu N, Mohideen P, Mudaliar S, Henry RR, Kahn BB.

Diabetes. 2002 Feb;51(2):443-8.PMID: 11812753 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of glucose transport and insulin signaling by troglitazone or metformin in adipose tissue of type 2 diabetic subjects.

Ciaraldi TP, Kong AP, Chu NV, Kim DD, Baxi S, Loviscach M, Plodkowski R, Reitz R, Caulfield M, Mudaliar S, Henry RR.

Diabetes. 2002 Jan;51(1):30-6.PMID: 11756319 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of the long-acting insulin analog insulin glargine on cultured human skeletal muscle cells: comparisons to insulin and IGF-I.

Ciaraldi TP, Carter L, Seipke G, Mudaliar S, Henry RR.

J Clin Endocrinol Metab. 2001 Dec;86(12):5838-47.PMID: 11739448 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired muscle glycogen synthase in type 2 diabetes is associated with diminished phosphatidylinositol 3-kinase activation.

Nikoulina SE, Ciaraldi TP, Carter L, Mudaliar S, Park KS, Henry RR.

J Clin Endocrinol Metab. 2001 Sep;86(9):4307-14.PMID: 11549666 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinoid X receptor expression in skeletal muscle of nondiabetic, obese and type 2 diabetic individuals.

Codner E, Loviscach M, Ciaraldi TP, Rehman N, Carter L, Mudaliar S, Henry RR.

Metabolism. 2001 Jul;50(7):830-4.PMID: 11436190 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor (PPAR) gamma and retinoid X receptor (RXR) agonists have complementary effects on glucose and lipid metabolism in human skeletal muscle.

Cha BS, Ciaraldi TP, Carter L, Nikoulina SE, Mudaliar S, Mukherjee R, Paterniti JR Jr, Henry RR.

Diabetologia. 2001 Apr;44(4):444-52.PMID: 11357475 [PubMed - indexed for MEDLINE]Related articles

Molecular defects of insulin action in the polycystic ovary syndrome: possible tissue specificity.

Ciaraldi TP.

J Pediatr Endocrinol Metab. 2000;13 Suppl 5:1291-3. Review.PMID: 11117672 [PubMed - indexed for MEDLINE]Related articles

Induction of insulin resistance in human skeletal muscle cells by downregulation of glycogen synthase protein expression.

Park KS, Ciaraldi TP, Carter L, Mudaliar S, Nikoulina SE, Webster NJ, Henry RR.

Metabolism. 2000 Aug;49(8):962-8.PMID: 10954011 [PubMed - indexed for MEDLINE]Related articles

Protein kinase Ctheta expression is increased upon differentiation of human skeletal muscle cells: dysregulation in type 2 diabetic patients and a possible role for protein kinase Ctheta in insulin-stimulated glycogen synthase activity.

Chalfant CE, Ciaraldi TP, Watson JE, Nikoulina S, Henry RR, Cooper DR.

Endocrinology. 2000 Aug;141(8):2773-8.PMID: 10919262 [PubMed - indexed for MEDLINE]Related articlesFree article

Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes.

Nikoulina SE, Ciaraldi TP, Mudaliar S, Mohideen P, Carter L, Henry RR.

Diabetes. 2000 Feb;49(2):263-71.PMID: 10868943 [PubMed - indexed for MEDLINE]Related articlesFree article

Distribution of peroxisome proliferator-activated receptors (PPARs) in human skeletal muscle and adipose tissue: relation to insulin action.

Loviscach M, Rehman N, Carter L, Mudaliar S, Mohadeen P, Ciaraldi TP, Veerkamp JH, Henry RR.

Diabetologia. 2000 Mar;43(3):304-11.PMID: 10768091 [PubMed - indexed for MEDLINE]Related articles

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes.

Kim YB, Nikoulina SE, Ciaraldi TP, Henry RR, Kahn BB.

J Clin Invest. 1999 Sep;104(6):733-41.PMID: 10491408 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucosamine regulation of glucose metabolism in cultured human skeletal muscle cells: divergent effects on glucose transport/phosphorylation and glycogen synthase in non-diabetic and type 2 diabetic subjects.

Ciaraldi TP, Carter L, Nikoulina S, Mudaliar S, McClain DA, Henry RR.

Endocrinology. 1999 Sep;140(9):3971-80.PMID: 10465266 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of tumor necrosis factor-alpha on glucose metabolism in cultured human muscle cells from nondiabetic and type 2 diabetic subjects.

Ciaraldi TP, Carter L, Mudaliar S, Kern PA, Henry RR.

Endocrinology. 1998 Dec;139(12):4793-800.PMID: 9832415 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of insulin resistance in fibroblasts from subjects with polycystic ovary syndrome.

Ciaraldi TP, Morales AJ, Hickman MG, Odom-Ford R, Yen SS, Olefsky JM.

Metabolism. 1998 Aug;47(8):940-6.PMID: 9711989 [PubMed - indexed for MEDLINE]Related articles

Troglitazone effects on gene expression in human skeletal muscle of type II diabetes involve up-regulation of peroxisome proliferator-activated receptor-gamma.

Park KS, Ciaraldi TP, Lindgren K, Abrams-Carter L, Mudaliar S, Nikoulina SE, Tufari SR, Veerkamp JH, Vidal-Puig A, Henry RR.

J Clin Endocrinol Metab. 1998 Aug;83(8):2830-5.PMID: 9709955 [PubMed - indexed for MEDLINE]Related articlesFree article

Troglitazone regulation of glucose metabolism in human skeletal muscle cultures from obese type II diabetic subjects.

Park KS, Ciaraldi TP, Abrams-Carter L, Mudaliar S, Nikoulina SE, Henry RR.

J Clin Endocrinol Metab. 1998 May;83(5):1636-43.PMID: 9589670 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of effect of leptin on glucose transport, lipoprotein lipase, and insulin action in adipose and muscle cells.

Ranganathan S, Ciaraldi TP, Henry RR, Mudaliar S, Kern PA.

Endocrinology. 1998 May;139(5):2509-13.PMID: 9564865 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin signal transduction by a mutant human insulin receptor lacking the NPEY sequence. Evidence for an alternate mitogenic signaling pathway that is independent of Shc phosphorylation.

Berhanu P, Anderson C, Hickman M, Ciaraldi TP.

J Biol Chem. 1997 Sep 5;272(36):22884-90.PMID: 9278451 [PubMed - indexed for MEDLINE]Related articlesFree article

PPAR-gamma gene expression is elevated in skeletal muscle of obese and type II diabetic subjects.

Park KS, Ciaraldi TP, Abrams-Carter L, Mudaliar S, Nikoulina SE, Henry RR.

Diabetes. 1997 Jul;46(7):1230-4.PMID: 9200661 [PubMed - indexed for MEDLINE]Related articles

Regulation of glycogen synthase activity in cultured skeletal muscle cells from subjects with type II diabetes: role of chronic hyperinsulinemia and hyperglycemia.

Nikoulina SE, Ciaraldi TP, Abrams-Carter L, Mudaliar S, Park KS, Henry RR.

Diabetes. 1997 Jun;46(6):1017-24.PMID: 9166674 [PubMed - indexed for MEDLINE]Related articles

Cellular insulin resistance in adipocytes from obese polycystic ovary syndrome subjects involves adenosine modulation of insulin sensitivity.

Ciaraldi TP, Morales AJ, Hickman MG, Odom-Ford R, Olefsky JM, Yen SS.

J Clin Endocrinol Metab. 1997 May;82(5):1421-5.PMID: 9141527 [PubMed - indexed for MEDLINE]Related articlesFree article