PubMed

Arginase II knockout mouse displays a hypertensive phenotype despite a decreased vasoconstrictory profile.

Huynh NN, Andrews KL, Head GA, Khong SM, Mayorov DN, Murphy AJ, Lambert G, Kiriazis H, Xu Q, Du XJ, Chin-Dusting JP.

Hypertension. 2009 Aug;54(2):294-301. Epub 2009 Jun 22.PMID: 19546381 [PubMed - indexed for MEDLINE]Related articles

Dissociation of pentameric to monomeric C-reactive protein on activated platelets localizes inflammation to atherosclerotic plaques.

Eisenhardt SU, Habersberger J, Murphy A, Chen YC, Woollard KJ, Bassler N, Qian H, von Zur Muhlen C, Hagemeyer CE, Ahrens I, Chin-Dusting J, Bobik A, Peter K.

Circ Res. 2009 Jul 17;105(2):128-37. Epub 2009 Jun 11.PMID: 19520972 [PubMed - indexed for MEDLINE]Related articles

Reconstituted high-density lipoprotein increases plasma high-density lipoprotein anti-inflammatory properties and cholesterol efflux capacity in patients with type 2 diabetes.

Patel S, Drew BG, Nakhla S, Duffy SJ, Murphy AJ, Barter PJ, Rye KA, Chin-Dusting J, Hoang A, Sviridov D, Celermajer DS, Kingwell BA.

J Am Coll Cardiol. 2009 Mar 17;53(11):962-71.PMID: 19281927 [PubMed - indexed for MEDLINE]Related articles

Erythrocyte hemolysis and hemoglobin oxidation promote ferric chloride-induced vascular injury.

Woollard KJ, Sturgeon S, Chin-Dusting JP, Salem HH, Jackson SP.

J Biol Chem. 2009 May 8;284(19):13110-8. Epub 2009 Mar 10.PMID: 19276082 [PubMed - indexed for MEDLINE]Related articles

The anti inflammatory effects of high density lipoproteins.

Murphy AJ, Chin-Dusting JP, Sviridov D, Woollard KJ.

Curr Med Chem. 2009;16(6):667-75. Review.PMID: 19199930 [PubMed - indexed for MEDLINE]Related articles

The vascular effects of different arginase inhibitors in rat isolated aorta and mesenteric arteries.

Huynh NN, Harris EE, Chin-Dusting JF, Andrews KL.

Br J Pharmacol. 2009 Jan;156(1):84-93.PMID: 19133993 [PubMed - indexed for MEDLINE]Related articles

Association of acute ischemic stroke with the MTHFR C677T polymorphism but not with NOS3 gene polymorphisms in a Singapore population.

Moe KT, Woon FP, De Silva DA, Wong P, Koh TH, Kingwell B, Chin-Dusting J, Wong MC.

Eur J Neurol. 2008 Dec;15(12):1309-14.PMID: 19049547 [PubMed - indexed for MEDLINE]Related articles

Protein kinase C mediated inhibition of endothelial L-arginine transport is mediated by MARCKS protein.

Venardos K, Enriquez C, Marshall T, Chin-Dusting JP, Ahlers B, Kaye DM.

J Mol Cell Cardiol. 2009 Jan;46(1):86-92. Epub 2008 Oct 14.PMID: 18977358 [PubMed - indexed for MEDLINE]Related articles

Pathophysiological levels of soluble P-selectin mediate adhesion of leukocytes to the endothelium through Mac-1 activation.

Woollard KJ, Suhartoyo A, Harris EE, Eisenhardt SU, Jackson SP, Peter K, Dart AM, Hickey MJ, Chin-Dusting JP.

Circ Res. 2008 Nov 7;103(10):1128-38. Epub 2008 Sep 25.PMID: 18818407 [PubMed - indexed for MEDLINE]Related articlesFree article

Norfloxacin treatment for clinically significant portal hypertension: results of a randomised double-blind placebo-controlled crossover trial.

Kemp W, Colman J, Thompson K, Madan A, Vincent M, Chin-Dusting J, Kompa A, Krum H, Roberts S.

Liver Int. 2009 Mar;29(3):427-33. Epub 2008 Jul 29.PMID: 18673434 [PubMed - indexed for MEDLINE]Related articles

High-density lipoprotein reduces the human monocyte inflammatory response.

Murphy AJ, Woollard KJ, Hoang A, Mukhamedova N, Stirzaker RA, McCormick SP, Remaley AT, Sviridov D, Chin-Dusting J.

Arterioscler Thromb Vasc Biol. 2008 Nov;28(11):2071-7. Epub 2008 Jul 10.PMID: 18617650 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of freezing on high-density lipoprotein functionality.

Kekulawala JR, Murphy A, D'Souza W, Wai C, Chin-Dusting J, Kingwell B, Sviridov D, Mukhamedova N.

Anal Biochem. 2008 Aug 15;379(2):213-5. Epub 2008 May 7.PMID: 18503744 [PubMed - indexed for MEDLINE]Related articles

Antiatherogenic functionality of high density lipoprotein: how much versus how good.

Sviridov D, Mukhamedova N, Remaley AT, Chin-Dusting J, Nestel P.

J Atheroscler Thromb. 2008 Apr;15(2):52-62. Epub 2008 Apr 3. Review.PMID: 18385533 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced plaque formation induced by rosiglitazone in an STZ-diabetes mouse model of atherosclerosis is associated with downregulation of adhesion molecules.

Tikellis C, Jandeleit-Dahm KA, Sheehy K, Murphy A, Chin-Dusting J, Kling D, Sebokova E, Cooper ME, Mizrahi J, Woollard KJ.

Atherosclerosis. 2008 Jul;199(1):55-64. Epub 2008 Feb 21.PMID: 18093596 [PubMed - indexed for MEDLINE]Related articles

L-arginine transporters in cardiovascular disease: a novel therapeutic target.

Chin-Dusting JP, Willems L, Kaye DM.

Pharmacol Ther. 2007 Dec;116(3):428-36. Epub 2007 Aug 28. Review.PMID: 17915331 [PubMed - indexed for MEDLINE]Related articles

Reduced cardiovascular reactivity to stress but not feeding in renin enhancer knockout mice.

Jackson K, Head GA, Morris BJ, Chin-Dusting J, Jones E, La Greca L, Mayorov DN.

Am J Hypertens. 2007 Aug;20(8):893-9.PMID: 17679040 [PubMed - indexed for MEDLINE]Related articles

Advanced glycation of apolipoprotein A-I impairs its anti-atherogenic properties.

Hoang A, Murphy AJ, Coughlan MT, Thomas MC, Forbes JM, O'Brien R, Cooper ME, Chin-Dusting JP, Sviridov D.

Diabetologia. 2007 Aug;50(8):1770-9. Epub 2007 Jun 20.PMID: 17579831 [PubMed - indexed for MEDLINE]Related articles

C-reactive protein and Fc gamma RIIa functional polymorphisms are not associated with clinical presentation of stable and unstable angina.

Murphy A, White A, Nair R, Kingwell B, Duffy S, Chin-Dusting J, Woollard K.

Thromb Haemost. 2007 Apr;97(4):681-2. No abstract available. PMID: 17393036 [PubMed - indexed for MEDLINE]Related articles

Therapeutic targeting of p-selectin in atherosclerosis.

Woollard KJ, Chin-Dusting J.

Inflamm Allergy Drug Targets. 2007 Mar;6(1):69-74. Review.PMID: 17352691 [PubMed - indexed for MEDLINE]Related articles

Identification of a novel polymorphism in the 3'UTR of the L-arginine transporter gene SLC7A1: contribution to hypertension and endothelial dysfunction.

Yang Z, Venardos K, Jones E, Morris BJ, Chin-Dusting J, Kaye DM.

Circulation. 2007 Mar 13;115(10):1269-74. Epub 2007 Feb 26.PMID: 17325243 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis of endothelial nitric oxide synthase gene polymorphism with primary hypertension in a Singapore population.

Moe KT, Lim ST, Wong P, Chua T, DeSilva DA, Koh TH, Wong MC, Chin-Dusting J.

J Hum Hypertens. 2006 Dec;20(12):956-63. Epub 2006 Oct 5.PMID: 17024134 [PubMed - indexed for MEDLINE]Related articles

Response to Cigarettes and ADMA: The Smoke Hasn't Cleared Yet.

Zhang WZ, Venardos K, Chin-Dusting J, Kaye DM.

Hypertension. 2006 Aug 21. [Epub ahead of print] No abstract available. PMID: 16923997 [PubMed - as supplied by publisher]Related articles

Role of the endothelium on vasoactive agents in patients with liver cirrhosis.

Battaglia S, Angus P, Chin-Dusting JP.

J Gastroenterol Hepatol. 2006 Jul;21(7):1189-93.PMID: 16824074 [PubMed - indexed for MEDLINE]Related articles

Adverse effects of cigarette smoke on NO bioavailability: role of arginine metabolism and oxidative stress.

Zhang WZ, Venardos K, Chin-Dusting J, Kaye DM.

Hypertension. 2006 Aug;48(2):278-85. Epub 2006 Jun 26.PMID: 16801489 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated HDL cholesterol is functionally ineffective in cardiac transplant recipients: evidence for impaired reverse cholesterol transport.

Sviridov D, Chin-Dusting J, Nestel P, Kingwell B, Hoang A, Olchawa B, Starr J, Dart A.

Transplantation. 2006 Feb 15;81(3):361-6.PMID: 16477221 [PubMed - indexed for MEDLINE]Related articles

Amino acids, arginase and nitric oxide in vascular health.

Huynh NN, Chin-Dusting J.

Clin Exp Pharmacol Physiol. 2006 Jan-Feb;33(1-2):1-8. Review.PMID: 16445692 [PubMed - indexed for MEDLINE]Related articles

Effect of dietary supplementation with beta-casein A1 or A2 on markers of disease development in individuals at high risk of cardiovascular disease.

Chin-Dusting J, Shennan J, Jones E, Williams C, Kingwell B, Dart A.

Br J Nutr. 2006 Jan;95(1):136-44.PMID: 16441926 [PubMed - indexed for MEDLINE]Related articles

Raised plasma soluble P-selectin in peripheral arterial occlusive disease enhances leukocyte adhesion.

Woollard KJ, Kling D, Kulkarni S, Dart AM, Jackson S, Chin-Dusting J.

Circ Res. 2006 Jan 6;98(1):149-56. Epub 2005 Dec 8.PMID: 16339486 [PubMed - indexed for MEDLINE]Related articlesFree article

Outlook: finding improved medicines: the role of academic-industrial collaboration.

Chin-Dusting J, Mizrahi J, Jennings G, Fitzgerald D.

Nat Rev Drug Discov. 2005 Nov;4(11):891-7. Review.PMID: 16247439 [PubMed - indexed for MEDLINE]Related articles

Responses to neither exogenous nor endogenous endothelin-1 are altered in patients with hypercholesterolemia.

Boak LM, Dart AM, Duffy SJ, Chin-Dusting JP.

J Lipid Res. 2005 Dec;46(12):2667-72. Epub 2005 Sep 21.PMID: 16177446 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypercholesterolemia and endothelium dysfunction: role of dietary supplementation as vascular protective agents.

Boak L, Chin-Dusting JP.

Curr Vasc Pharmacol. 2004 Jan;2(1):45-52. Review.PMID: 15320832 [PubMed - indexed for MEDLINE]Related articles

The isoflavone metabolite dehydroequol produces vasodilatation in human resistance arteries via a nitric oxide-dependent mechanism.

Chin-Dusting JP, Boak L, Husband A, Nestel PJ.

Atherosclerosis. 2004 Sep;176(1):45-8.PMID: 15306173 [PubMed - indexed for MEDLINE]Related articles

Nitric oxide and the hyperdynamic circulation in cirrhosis: is there a role for selective intestinal decontamination?

Rasaratnam B, Connelly N, Chin-Dusting J.

Clin Sci (Lond). 2004 Nov;107(5):425-34. Review.PMID: 15270715 [PubMed - indexed for MEDLINE]Related articles

Responses to endothelin-1 in patients with advanced cirrhosis before and after liver transplantation.

Angus PW, Vaughan RB, Chin-Dusting JP.

Gut. 2004 May;53(5):773. No abstract available. PMID: 15082606 [PubMed - indexed for MEDLINE]Related articlesFree article

An age-related decline in endothelial function is not associated with alterations in L-arginine transport in humans.

Ahlers BA, Parnell MM, Chin-Dusting JP, Kaye DM.

J Hypertens. 2004 Feb;22(2):321-7.PMID: 15076190 [PubMed - indexed for MEDLINE]Related articles

Plasma C-reactive protein, but not protein S, VCAM-1, von Willebrand factor or P-selectin, is associated with endothelium dysfunction in coronary artery disease.

Anderson R, Dart AM, Starr J, Shaw J, Chin-Dusting JP.

Atherosclerosis. 2004 Feb;172(2):345-51.PMID: 15019545 [PubMed - indexed for MEDLINE]Related articles

In vivo and in vitro evidence for ACh-stimulated L-arginine uptake.

Parnell MM, Chin-Dusting JP, Starr J, Kaye DM.

Am J Physiol Heart Circ Physiol. 2004 Jul;287(1):H395-400. Epub 2004 Mar 11.PMID: 15016636 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired acetylcholine-induced release of nitric oxide in the aorta of male aromatase-knockout mice: regulation of nitric oxide production by endogenous sex hormones in males.

Kimura M, Sudhir K, Jones M, Simpson E, Jefferis AM, Chin-Dusting JP.

Circ Res. 2003 Dec 12;93(12):1267-71. Epub 2003 Oct 23.PMID: 14576203 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for altered vascular responses to exogenous endothelin-1 in patients with advanced cirrhosis with restoration of the normal vasoconstrictor response following successful liver transplantation.

Vaughan RB, Angus PW, Chin-Dusting JP.

Gut. 2003 Oct;52(10):1505-10.PMID: 12970146 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of selective intestinal decontamination on the hyperdynamic circulatory state in cirrhosis. A randomized trial.

Rasaratnam B, Kaye D, Jennings G, Dudley F, Chin-Dusting J.

Ann Intern Med. 2003 Aug 5;139(3):186-93.PMID: 12899586 [PubMed - indexed for MEDLINE]Related articlesFree article

Age and the treatment gap in the use of statins.

Chin-Dusting JP, Dart AM.

Lancet. 2003 Jun 7;361(9373):1925-6. No abstract available. PMID: 12801733 [PubMed - indexed for MEDLINE]Related articles

Current pharmacotherapy in the management of cirrhosis: focus on the hyperdynamic circulation.

Vaughan RB, Chin-Dusting JP.

Expert Opin Pharmacother. 2003 May;4(5):625-37. Review.PMID: 12739989 [PubMed - indexed for MEDLINE]Related articles

L-arginine transport in humans with cortisol-induced hypertension.

Chin-Dusting JP, Ahlers BA, Kaye DM, Kelly JJ, Whitworth JA.

Hypertension. 2003 Jun;41(6):1336-40. Epub 2003 Apr 21.PMID: 12707296 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-dose atorvastatin therapy does not augment endothelial function in active hypercholesterolaemic males.

Parnell MM, Chin-Dusting JP, Starr J, Kaye DM.

Br J Clin Pharmacol. 2003 Feb;55(2):212-5.PMID: 12580994 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin inhibits acetylcholine responses in rat isolated mesenteric arteries via a non-nitric oxide nonprostanoid pathway.

Kimura M, Jefferis AM, Watanabe H, Chin-Dusting J.

Hypertension. 2002 Jan;39(1):35-40.PMID: 11799075 [PubMed - indexed for MEDLINE]Related articlesFree article

The vascular activity of some isoflavone metabolites: implications for a cardioprotective role.

Chin-Dusting JP, Fisher LJ, Lewis TV, Piekarska A, Nestel PJ, Husband A.

Br J Pharmacol. 2001 Jun;133(4):595-605.PMID: 11399677 [PubMed - indexed for MEDLINE]Related articlesFree article

Post-prandial remnant lipids impair arterial compliance.

Nestel PJ, Shige H, Pomeroy S, Cehun M, Chin-Dusting J.

J Am Coll Cardiol. 2001 Jun 1;37(7):1929-35.PMID: 11401134 [PubMed - indexed for MEDLINE]Related articles

Lipids and atherosclerosis: clinical management of hypercholesterolaemia.

Chin-Dusting JP, Shaw JA.

Expert Opin Pharmacother. 2001 Mar;2(3):419-30. Review.PMID: 11336596 [PubMed - indexed for MEDLINE]Related articles

Diurnal variation in endothelium-dependent vasodilatation is not apparent in coronary artery disease.

Shaw JA, Chin-Dusting JP, Kingwell BA, Dart AM.

Circulation. 2001 Feb 13;103(6):806-12.PMID: 11171787 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo and in vitro evidence for impaired arginine transport in human heart failure.

Kaye DM, Ahlers BA, Autelitano DJ, Chin-Dusting JP.

Circulation. 2000 Nov 28;102(22):2707-12.PMID: 11094036 [PubMed - indexed for MEDLINE]Related articlesFree article