PubMed

Effects of Insulin on the Metabolic Control of Hepatic Gluconeogenesis in vivo.

Edgerton DS, Ramnanan CJ, Grueter CA, Johnson KM, Lautz M, Neal DW, Williams PE, Cherrington AD.

Diabetes. 2009 Sep 15. [Epub ahead of print]PMID: 19755527 [PubMed - as supplied by publisher]Related articles

A physiological increase in the hepatic glycogen level does not affect the response of net hepatic glucose uptake to insulin.

Winnick JJ, An Z, Moore MC, Ramnanan CJ, Farmer B, Shiota M, Cherrington AD.

Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E358-66. Epub 2009 May 26.PMID: 19470836 [PubMed - indexed for MEDLINE]Related articles

Portal infusion of escitalopram enhances hepatic glucose disposal in conscious dogs.

An Z, Moore MC, Winnick JJ, Farmer B, Neal DW, Lautz M, Smith M, Rodewald T, Cherrington AD.

Eur J Pharmacol. 2009 Apr 1;607(1-3):251-7.PMID: 19326481 [PubMed - indexed for MEDLINE]Related articles

Current strategies for the inhibition of hepatic glucose production in type 2 diabetes.

Edgerton DS, Johnson KM, Cherrington AD.

Front Biosci. 2009 Jan 1;14:1169-81. Review.PMID: 19273123 [PubMed - indexed for MEDLINE]Related articles

Inhaled insulin is associated with prolonged enhancement of glucose disposal in muscle and liver in the canine.

Edgerton DS, Cherrington AD, Neal DW, Scott M, Lautz M, Brown N, Petro J, Hobbs CH, Leach C, Del Parigi A, Strack TR.

J Pharmacol Exp Ther. 2009 Mar;328(3):970-5. Epub 2008 Dec 19.PMID: 19098161 [PubMed - indexed for MEDLINE]Related articles

Portal infusion of amino acids is more efficient than peripheral infusion in stimulating liver protein synthesis at the same hepatic amino acid load in dogs.

Dardevet D, Kimball SR, Jefferson LS, Cherrington AD, Rémond D, DiCostanzo CA, Moore MC.

Am J Clin Nutr. 2008 Oct;88(4):986-96.PMID: 18842785 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of dipeptidyl peptidase-4 by vildagliptin during glucagon-like Peptide 1 infusion increases liver glucose uptake in the conscious dog.

Edgerton DS, Johnson KM, Neal DW, Scott M, Hobbs CH, Zhang X, Duttaroy A, Cherrington AD.

Diabetes. 2009 Jan;58(1):243-9. Epub 2008 Oct 7.PMID: 18840785 [PubMed - indexed for MEDLINE]Related articlesFree article

Central versus peripheral glucose sensing and the response to hypoglycemia.

Cherrington AD.

Diabetes. 2008 May;57(5):1158-9. No abstract available. PMID: 18443372 [PubMed - indexed for MEDLINE]Related articlesFree article

Intraportal administration of neuropeptide Y and hepatic glucose metabolism.

Nishizawa M, Shiota M, Moore MC, Gustavson SM, Neal DW, Cherrington AD.

Am J Physiol Regul Integr Comp Physiol. 2008 Apr;294(4):R1197-204. Epub 2008 Jan 30.PMID: 18234742 [PubMed - indexed for MEDLINE]Related articles

Hepatic portal venous delivery of a nitric oxide synthase inhibitor enhances net hepatic glucose uptake.

Moore MC, Dicostanzo CA, Smith MS, Farmer B, Rodewald TD, Neal DW, Williams PE, Cherrington AD.

Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E768-77. Epub 2008 Jan 22.PMID: 18212022 [PubMed - indexed for MEDLINE]Related articlesFree article

Intraportally delivered GLP-1, in the presence of hyperglycemia induced via peripheral glucose infusion, does not change whole body glucose utilization.

Johnson KM, Edgerton DS, Rodewald T, Scott M, Farmer B, Neal D, Cherrington AD.

Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E380-4. Epub 2007 Dec 4.PMID: 18056788 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of the nitric oxide donor SIN-1 on net hepatic glucose uptake in the conscious dog.

An Z, DiCostanzo CA, Moore MC, Edgerton DS, Dardevet DP, Neal DW, Cherrington AD.

Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E300-6. Epub 2007 Nov 20.PMID: 18029444 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin action on the liver in vivo.

Cherrington AD, Moore MC, Sindelar DK, Edgerton DS.

Biochem Soc Trans. 2007 Nov;35(Pt 5):1171-4. Review.PMID: 17956305 [PubMed - indexed for MEDLINE]Related articles

Intraportal GLP-1 infusion increases nonhepatic glucose utilization without changing pancreatic hormone levels.

Johnson KM, Edgerton DS, Rodewald T, Scott M, Farmer B, Neal D, Cherrington AD.

Am J Physiol Endocrinol Metab. 2007 Oct;293(4):E1085-91. Epub 2007 Aug 7.PMID: 17684104 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of vagal cooling on canine hepatic glucose metabolism in the presence of hyperglycemia of peripheral origin.

DiCostanzo CA, Dardevet DP, Williams PE, Courtney Moore M, Hastings JR, Neal DW, Cherrington AD.

Metabolism. 2007 Jun;56(6):814-24.PMID: 17512315 [PubMed - indexed for MEDLINE]Related articles

Triglyceride uptake and lipoprotein lipase-generated fatty acid spillover in the splanchnic bed of dogs.

Nelson RH, Edgerton DS, Basu R, Roesner JC, Cherrington AD, Miles JM.

Diabetes. 2007 Jul;56(7):1850-5. Epub 2007 Apr 6.PMID: 17416801 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel glucagon receptor antagonist, NNC 25-0926, blunts hepatic glucose production in the conscious dog.

Rivera N, Everett-Grueter CA, Edgerton DS, Rodewald T, Neal DW, Nishimura E, Larsen MO, Jacobsen LO, Kristensen K, Brand CL, Cherrington AD.

J Pharmacol Exp Ther. 2007 May;321(2):743-52. Epub 2007 Feb 16.PMID: 17308040 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of hepatic metabolism by enteral delivery of nutrients.

Dardevet D, Moore MC, Remond D, Everett-Grueter CA, Cherrington AD.

Nutr Res Rev. 2006 Dec;19(2):161-73.PMID: 19079883 [PubMed - in process]Related articles

Inhalation of human insulin (exubera) augments the efficiency of muscle glucose uptake in vivo.

Edgerton DS, Cherrington AD, Williams P, Neal DW, Scott M, Bowen L, Wilson W, Hobbs CH, Leach C, Kuo MC, Strack TR.

Diabetes. 2006 Dec;55(12):3604-10.PMID: 17130510 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhalation of human insulin is associated with improved insulin action compared with subcutaneous injection and endogenous secretion in dogs.

Edgerton DS, Stettler KM, Neal DW, Scott M, Bowen L, Wilson W, Hobbs CH, Leach C, Strack TR, Cherrington AD.

J Pharmacol Exp Ther. 2006 Dec;319(3):1258-64. Epub 2006 Sep 8.PMID: 16963622 [PubMed - indexed for MEDLINE]Related articlesFree article

2005 Presidential Address: Diabetes: past, present, and future.

Cherrington AD.

Diabetes Care. 2006 Sep;29(9):2158-64. No abstract available. PMID: 16936170 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective antagonism of the hepatic glucocorticoid receptor reduces hepatic glucose production.

Edgerton DS, Jacobson PB, Opgenorth TJ, Zinker B, Beno D, von Geldern T, Ohman L, Scott M, Neal D, Cherrington AD.

Metabolism. 2006 Sep;55(9):1255-62.PMID: 16919547 [PubMed - indexed for MEDLINE]Related articles

The effect of an acute elevation of NEFA concentrations on glucagon-stimulated hepatic glucose output.

Everett-Grueter C, Edgerton DS, Donahue EP, Vaughan S, Chu CA, Sindelar DK, Cherrington AD.

Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E449-59. Epub 2006 Apr 11.PMID: 16608886 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin's direct effects on the liver dominate the control of hepatic glucose production.

Edgerton DS, Lautz M, Scott M, Everett CA, Stettler KM, Neal DW, Chu CA, Cherrington AD.

J Clin Invest. 2006 Feb;116(2):521-7.PMID: 16453026 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet auto-transplantation into an omental or splenic site results in a normal beta cell but abnormal alpha cell response to mild non-insulin-induced hypoglycemia.

Gustavson SM, Rajotte RV, Hunkeler D, Lakey JR, Edgerton DS, Neal DW, Snead WL, Penaloza AR, Cherrington AD.

Am J Transplant. 2005 Oct;5(10):2368-77.PMID: 16162184 [PubMed - indexed for MEDLINE]Related articles

Role of the hepatic sympathetic nerves in the regulation of net hepatic glucose uptake and the mediation of the portal glucose signal.

Dicostanzo CA, Dardevet DP, Neal DW, Lautz M, Allen E, Snead W, Cherrington AD.

Am J Physiol Endocrinol Metab. 2006 Jan;290(1):E9-E16. Epub 2005 Aug 16.PMID: 16105863 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin secretion-independent effects of GLP-1 on canine liver glucose metabolism do not involve portal vein GLP-1 receptors.

Dardevet D, Moore MC, DiCostanzo CA, Farmer B, Neal DW, Snead W, Lautz M, Cherrington AD.

Am J Physiol Gastrointest Liver Physiol. 2005 Nov;289(5):G806-14. Epub 2005 Jul 28.PMID: 16051922 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of hepatic insulin receptors in the regulation of glucose production.

Cherrington AD.

J Clin Invest. 2005 May;115(5):1136-9.PMID: 15864342 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhalation of insulin (Exubera) is associated with augmented disposal of portally infused glucose in dogs.

Edgerton DS, Neal DW, Scott M, Bowen L, Wilson W, Hobbs CH, Leach C, Sivakumaran S, Strack TR, Cherrington AD.

Diabetes. 2005 Apr;54(4):1164-70.PMID: 15793257 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of continuous and pulsatile insulin delivery on net hepatic glucose uptake.

Grubert JM, Lautz M, Lacy DB, Moore MC, Farmer B, Penaloza A, Cherrington AD, McGuinness OP.

Am J Physiol Endocrinol Metab. 2005 Aug;289(2):E232-40. Epub 2005 Mar 8.PMID: 15755768 [PubMed - indexed for MEDLINE]Related articlesFree article

Portal 5-hydroxytryptophan infusion enhances glucose disposal in conscious dogs.

Moore MC, Kimura K, Shibata H, Honjoh T, Saito M, Everett CA, Smith MS, Cherrington AD.

Am J Physiol Endocrinol Metab. 2005 Aug;289(2):E225-31. Epub 2005 Mar 8.PMID: 15755767 [PubMed - indexed for MEDLINE]Related articlesFree article

Simulated first-phase insulin release using Humulin or insulin analog HIM2 is associated with prolonged improvement in postprandial glycemia.

DiCostanzo CA, Moore MC, Lautz M, Scott M, Farmer B, Everett CA, Still JG, Higgins A, Cherrington AD.

Am J Physiol Endocrinol Metab. 2005 Jul;289(1):E46-52. Epub 2005 Feb 15.PMID: 15713685 [PubMed - indexed for MEDLINE]Related articlesFree article

Inclusion of low amounts of fructose with an intraportal glucose load increases net hepatic glucose uptake in the presence of relative insulin deficiency in dog.

Shiota M, Galassetti P, Igawa K, Neal DW, Cherrington AD.

Am J Physiol Endocrinol Metab. 2005 Jun;288(6):E1160-7. Epub 2005 Jan 25.PMID: 15671083 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction of a selective serotonin reuptake inhibitor with insulin in the control of hepatic glucose uptake in conscious dogs.

Moore MC, DiCostanzo CA, Dardevet D, Lautz M, Farmer B, Cherrington AD.

Am J Physiol Endocrinol Metab. 2005 Mar;288(3):E556-63. Epub 2004 Nov 2.PMID: 15522992 [PubMed - indexed for MEDLINE]Related articlesFree article

Portal infusion of a selective serotonin reuptake inhibitor enhances hepatic glucose disposal in conscious dogs.

Moore MC, DiCostanzo CA, Dardevet D, Lautz M, Farmer B, Neal DW, Cherrington AD.

Am J Physiol Endocrinol Metab. 2004 Dec;287(6):E1057-63. Epub 2004 Aug 17.PMID: 15315909 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of hyperglycemia, glucagon, and epinephrine on renal glucose release in the conscious dog.

Gustavson SM, Chu CA, Nishizawa M, Neal D, Farmer B, Yang Y, Donahue EP, Flakoll P, Cherrington AD.

Metabolism. 2004 Jul;53(7):933-41.PMID: 15254890 [PubMed - indexed for MEDLINE]Related articles

Vagal cooling and concomitant portal norepinephrine infusion do not reduce net hepatic glucose uptake in conscious dogs.

Cardin S, Pagliassotti MJ, Moore MC, Edgerton DS, Lautz M, Farmer B, Neal DW, Cherrington AD.

Am J Physiol Regul Integr Comp Physiol. 2004 Oct;287(4):R742-8. Epub 2004 May 27.PMID: 15166005 [PubMed - indexed for MEDLINE]Related articles

Inhalation of insulin in dogs: assessment of insulin levels and comparison to subcutaneous injection.

Cherrington AD, Neal DW, Edgerton DS, Glass D, Bowen L, Hobbs CH, Leach C, Rosskamp R, Strack TR.

Diabetes. 2004 Apr;53(4):877-81.PMID: 15047601 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-independent effects of GLP-1 on canine liver glucose metabolism: duration of infusion and involvement of hepatoportal region.

Dardevet D, Moore MC, Neal D, DiCostanzo CA, Snead W, Cherrington AD.

Am J Physiol Endocrinol Metab. 2004 Jul;287(1):E75-81. Epub 2004 Mar 16.PMID: 15026303 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective stimulation of G-6-Pase catalytic subunit but not G-6-P transporter gene expression by glucagon in vivo and cAMP in situ.

Hornbuckle LA, Everett CA, Martin CC, Gustavson SS, Svitek CA, Oeser JK, Neal DW, Cherrington AD, O'Brien RM.

Am J Physiol Endocrinol Metab. 2004 May;286(5):E795-808. Epub 2004 Jan 13.PMID: 14722027 [PubMed - indexed for MEDLINE]Related articlesFree article

Nonesterified fatty acids and hepatic glucose metabolism in the conscious dog.

Moore MC, Satake S, Lautz M, Soleimanpour SA, Neal DW, Smith M, Cherrington AD.

Diabetes. 2004 Jan;53(1):32-40.PMID: 14693695 [PubMed - indexed for MEDLINE]Related articlesFree article

Portal serotonin infusion and glucose disposal in conscious dogs.

Moore MC, Geho WB, Lautz M, Farmer B, Neal DW, Cherrington AD.

Diabetes. 2004 Jan;53(1):14-20. Erratum in: Diabetes. 2004 Mar;53(3):874. PMID: 14693692 [PubMed - indexed for MEDLINE]Related articlesFree article

Rapid translocation of hepatic glucokinase in response to intraduodenal glucose infusion and changes in plasma glucose and insulin in conscious rats.

Chu CA, Fujimoto Y, Igawa K, Grimsby J, Grippo JF, Magnuson MA, Cherrington AD, Shiota M.

Am J Physiol Gastrointest Liver Physiol. 2004 Apr;286(4):G627-34. Epub 2003 Dec 4.PMID: 14656711 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of hyperglycemia on hepatic gluconeogenic flux during glycogen phosphorylase inhibition in the conscious dog.

Edgerton DS, Cardin S, Neal D, Farmer B, Lautz M, Pan C, Cherrington AD.

Am J Physiol Endocrinol Metab. 2004 Apr;286(4):E510-22. Epub 2003 Nov 25.PMID: 14644767 [PubMed - indexed for MEDLINE]Related articlesFree article

A fall in portal vein insulin does not cause the alpha-cell response to mild, non-insulin-induced hypoglycemia in conscious dogs.

Gustavson SM, Nishizawa M, Farmer B, Neal D, Brissova M, Powers AC, Cherrington AD.

Metabolism. 2003 Nov;52(11):1418-25.PMID: 14624400 [PubMed - indexed for MEDLINE]Related articles

Unlike mice, dogs exhibit effective glucoregulation during low-dose portal and peripheral glucose infusion.

Moore MC, Cardin S, Edgerton DS, Farmer B, Neal DW, Lautz M, Cherrington AD.

Am J Physiol Endocrinol Metab. 2004 Feb;286(2):E226-33. Epub 2003 Sep 30.PMID: 14519598 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of hepatic and peripheral glucose disposal.

Moore MC, Cherrington AD, Wasserman DH.

Best Pract Res Clin Endocrinol Metab. 2003 Sep;17(3):343-64. Review.PMID: 12962690 [PubMed - indexed for MEDLINE]Related articles

Effects of fructose on hepatic glucose metabolism.

McGuinness OP, Cherrington AD.

Curr Opin Clin Nutr Metab Care. 2003 Jul;6(4):441-8. Review.PMID: 12806219 [PubMed - indexed for MEDLINE]Related articles

Chronic hepatic artery ligation does not prevent liver from differentiating portal vs. peripheral glucose delivery.

Moore MC, Burish MJ, Farmer B, Neal DW, Pan C, Cherrington AD.

Am J Physiol Endocrinol Metab. 2003 Oct;285(4):E845-53. Epub 2003 May 28.PMID: 12773306 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon's actions are modified by the combination of epinephrine and gluconeogenic precursor infusion.

Gustavson SM, Chu CA, Nishizawa M, Farmer B, Neal D, Yang Y, Vaughan S, Donahue EP, Flakoll P, Cherrington AD.

Am J Physiol Endocrinol Metab. 2003 Sep;285(3):E534-44. Epub 2003 May 7.PMID: 12736160 [PubMed - indexed for MEDLINE]Related articlesFree article