PubMed

Hepatic energy state is regulated by glucagon receptor signaling in mice.

Berglund ED, Lee-Young RS, Lustig DG, Lynes SE, Donahue EP, Camacho RC, Meredith ME, Magnuson MA, Charron MJ, Wasserman DH.

J Clin Invest. 2009 Aug;119(8):2412-22.PMID: 19662685 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass.

Gelling RW, Vuguin PM, Du XQ, Cui L, Rømer J, Pederson RA, Leiser M, Sørensen H, Holst JJ, Fledelius C, Johansen PB, Fleischer N, McIntosh CH, Nishimura E, Charron MJ.

Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E695-707. Epub 2009 Jul 14.PMID: 19602585 [PubMed - indexed for MEDLINE]Related articles

Maternal Substrate Utilization Programs the Development of the Metabolic Syndrome in Male Mice Exposed to High Fat in Utero.

Hartil K, Vuguin PM, Kruse M, Schmuel E, Fiallo A, Vargas C, Warner MJ, Durand JL, Jelicks LA, Charron MJ.

Pediatr Res. 2009 Jul 1. [Epub ahead of print]PMID: 19581843 [PubMed - as supplied by publisher]Related articles

The glucagon receptor is required for the adaptive metabolic response to fasting.

Longuet C, Sinclair EM, Maida A, Baggio LL, Maziarz M, Charron MJ, Drucker DJ.

Cell Metab. 2008 Nov;8(5):359-71.PMID: 19046568 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon receptor signaling is essential for control of murine hepatocyte survival.

Sinclair EM, Yusta B, Streutker C, Baggio LL, Koehler J, Charron MJ, Drucker DJ.

Gastroenterology. 2008 Dec;135(6):2096-106. Epub 2008 Aug 3.PMID: 18809404 [PubMed - indexed for MEDLINE]Related articles

Hepatic response to restoration of GLUT4 in skeletal muscle of GLUT4 null mice.

Ranalletta M, Du XQ, Seki Y, Glenn AS, Kruse M, Fiallo A, Estrada I, Tsao TS, Stenbit AE, Katz EB, Charron MJ.

Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1178-87. Epub 2007 Aug 21.PMID: 17711992 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose kinetics and exercise tolerance in mice lacking the GLUT4 glucose transporter.

Fueger PT, Li CY, Ayala JE, Shearer J, Bracy DP, Charron MJ, Rottman JN, Wasserman DH.

J Physiol. 2007 Jul 15;582(Pt 2):801-12. Epub 2007 May 10.PMID: 17495042 [PubMed - indexed for MEDLINE]Related articlesFree article

Corticosterone impairs insulin-stimulated translocation of GLUT4 in the rat hippocampus.

Piroli GG, Grillo CA, Reznikov LR, Adams S, McEwen BS, Charron MJ, Reagan LP.

Neuroendocrinology. 2007;85(2):71-80. Epub 2007 Apr 5.PMID: 17426391 [PubMed - indexed for MEDLINE]Related articles

Preserved expression of GLUT4 prevents enhanced agonist-induced vascular reactivity and MYPT1 phosphorylation in hypertensive mouse aorta.

Atkins KB, Prezkop A, Park JL, Saha J, Duquaine D, Charron MJ, Olson AL, Brosius FC 3rd.

Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H402-8. Epub 2007 Mar 16.PMID: 17369465 [PubMed - indexed for MEDLINE]Related articlesFree article

Nestin expression in pancreatic endocrine and exocrine cells of mice lacking glucagon signaling.

Kedees MH, Guz Y, Vuguin PM, Vargas C, Cui L, Steiner DF, Charron MJ, Teitelman G.

Dev Dyn. 2007 Apr;236(4):1126-33.PMID: 17366624 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoglycemia leads to age-related loss of vision.

Umino Y, Everhart D, Solessio E, Cusato K, Pan JC, Nguyen TH, Brown ET, Hafler R, Frio BA, Knox BE, Engbretson GA, Haeri M, Cui L, Glenn AS, Charron MJ, Barlow RB.

Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19541-5. Epub 2006 Dec 11.PMID: 17159157 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia.

Conarello SL, Jiang G, Mu J, Li Z, Woods J, Zycband E, Ronan J, Liu F, Roy RS, Zhu L, Charron MJ, Zhang BB.

Diabetologia. 2007 Jan;50(1):142-50. Epub 2006 Nov 28.PMID: 17131145 [PubMed - indexed for MEDLINE]Related articles

GLUT1 and GLUT8 in endometrium and endometrial adenocarcinoma.

Goldman NA, Katz EB, Glenn AS, Weldon RH, Jones JG, Lynch U, Fezzari MJ, Runowicz CD, Goldberg GL, Charron MJ.

Mod Pathol. 2006 Nov;19(11):1429-36. Epub 2006 Aug 4.PMID: 16892013 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose transporter expression in skeletal muscle of endurance-trained individuals.

Seki Y, Berggren JR, Houmard JA, Charron MJ.

Med Sci Sports Exerc. 2006 Jun;38(6):1088-92.PMID: 16775550 [PubMed - indexed for MEDLINE]Related articles

Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturation.

Vuguin PM, Kedees MH, Cui L, Guz Y, Gelling RW, Nejathaim M, Charron MJ, Teitelman G.

Endocrinology. 2006 Sep;147(9):3995-4006. Epub 2006 Apr 20.PMID: 16627579 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of chronic Akt activation on glucose uptake in the heart.

Matsui T, Nagoshi T, Hong EG, Luptak I, Hartil K, Li L, Gorovits N, Charron MJ, Kim JK, Tian R, Rosenzweig A.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E789-97. Epub 2005 Dec 13.PMID: 16352665 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic modification of the heart: transgenic modification of cardiac lipid and carbohydrate utilization.

Hartil K, Charron MJ.

J Mol Cell Cardiol. 2005 Oct;39(4):581-93. Review. Erratum in: J Mol Cell Cardiol. 2006 Feb;40(2):329-32. PMID: 16140322 [PubMed - indexed for MEDLINE]Related articles

GLUT4 facilitative glucose transporter specifically and differentially contributes to agonist-induced vascular reactivity in mouse aorta.

Park JL, Loberg RD, Duquaine D, Zhang H, Deo BK, Ardanaz N, Coyle J, Atkins KB, Schin M, Charron MJ, Kumagai AK, Pagano PJ, Brosius FC 3rd.

Arterioscler Thromb Vasc Biol. 2005 Aug;25(8):1596-602. Epub 2005 May 12.PMID: 15890973 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of GLUT-4 null mice to study skeletal muscle glucose uptake.

Charron MJ, Gorovits N, Laidlaw JS, Ranalletta M, Katz EB.

Clin Exp Pharmacol Physiol. 2005 Apr;32(4):308-13. Review.PMID: 15810997 [PubMed - indexed for MEDLINE]Related articles

Altered hepatic and muscle substrate utilization provoked by GLUT4 ablation.

Ranalletta M, Jiang H, Li J, Tsao TS, Stenbit AE, Yokoyama M, Katz EB, Charron MJ.

Diabetes. 2005 Apr;54(4):935-43.PMID: 15793230 [PubMed - indexed for MEDLINE]Related articlesFree article

Localization of the GLUT8 glucose transporter in murine kidney and regulation in vivo in nondiabetic and diabetic conditions.

Schiffer M, Susztak K, Ranalletta M, Raff AC, Böttinger EP, Charron MJ.

Am J Physiol Renal Physiol. 2005 Jul;289(1):F186-93. Epub 2005 Mar 1.PMID: 15741607 [PubMed - indexed for MEDLINE]Related articlesFree article

Positherapy: targeted nuclear therapy of breast cancer with 18F-2-deoxy-2-fluoro-D-glucose.

Moadel RM, Weldon RH, Katz EB, Lu P, Mani J, Stahl M, Blaufox MD, Pestell RG, Charron MJ, Dadachova E.

Cancer Res. 2005 Feb 1;65(3):698-702.PMID: 15705862 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis.

Brissova M, Blaha M, Spear C, Nicholson W, Radhika A, Shiota M, Charron MJ, Wright CV, Powers AC.

Am J Physiol Endocrinol Metab. 2005 Apr;288(4):E707-14. Epub 2004 Nov 23.PMID: 15562255 [PubMed - indexed for MEDLINE]Related articlesFree article

Control of exercise-stimulated muscle glucose uptake by GLUT4 is dependent on glucose phosphorylation capacity in the conscious mouse.

Fueger PT, Hess HS, Posey KA, Bracy DP, Pencek RR, Charron MJ, Wasserman DH.

J Biol Chem. 2004 Dec 3;279(49):50956-61. Epub 2004 Sep 28.PMID: 15456776 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of insulin-stimulated muscle glucose uptake in the conscious mouse: role of glucose transport is dependent on glucose phosphorylation capacity.

Fueger PT, Hess HS, Bracy DP, Pencek RR, Posey KA, Charron MJ, Wasserman DH.

Endocrinology. 2004 Nov;145(11):4912-6. Epub 2004 Jul 29.PMID: 15284204 [PubMed - indexed for MEDLINE]Related articlesFree article

Delayed response of insulin-stimulated fluorine-18 deoxyglucose uptake in glucose transporter-4-null mice hearts.

Simões MV, Egert S, Ziegler S, Miyagawa M, Reder S, Lehner T, Nguyen N, Charron MJ, Schwaiger M.

J Am Coll Cardiol. 2004 May 5;43(9):1690-7.PMID: 15120832 [PubMed - indexed for MEDLINE]Related articles

Biphasic effects of stress upon GLUT8 glucose transporter expression and trafficking in the diabetic rat hippocampus.

Piroli GG, Grillo CA, Charron MJ, McEwen BS, Reagan LP.

Brain Res. 2004 Apr 23;1006(1):28-35.PMID: 15047021 [PubMed - indexed for MEDLINE]Related articles

Regulation of hepatic GLUT8 expression in normal and diabetic models.

Gorovits N, Cui L, Busik JV, Ranalletta M, Hauguel de-Mouzon S, Charron MJ.

Endocrinology. 2003 May;144(5):1703-11.PMID: 12697674 [PubMed - indexed for MEDLINE]Related articlesFree article

Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice.

Gelling RW, Du XQ, Dichmann DS, Romer J, Huang H, Cui L, Obici S, Tang B, Holst JJ, Fledelius C, Johansen PB, Rossetti L, Jelicks LA, Serup P, Nishimura E, Charron MJ.

Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1438-43. Epub 2003 Jan 24.PMID: 12552113 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral glucose administration stimulates the translocation of GLUT8 glucose transporter to the endoplasmic reticulum in the rat hippocampus.

Piroli GG, Grillo CA, Hoskin EK, Znamensky V, Katz EB, Milner TA, McEwen BS, Charron MJ, Reagan LP.

J Comp Neurol. 2002 Oct 14;452(2):103-14.PMID: 12271485 [PubMed - indexed for MEDLINE]Related articles

Improved insulin sensitivity and resistance to weight gain in mice null for the Ahsg gene.

Mathews ST, Singh GP, Ranalletta M, Cintron VJ, Qiang X, Goustin AS, Jen KL, Charron MJ, Jahnen-Dechent W, Grunberger G.

Diabetes. 2002 Aug;51(8):2450-8.PMID: 12145157 [PubMed - indexed for MEDLINE]Related articlesFree article

An increase in the myocardial PCr/ATP ratio in GLUT4 null mice.

Weiss RG, Chatham JC, Georgakopolous D, Charron MJ, Wallimann T, Kay L, Walzel B, Wang Y, Kass DA, Gerstenblith G, Chacko VP.

FASEB J. 2002 Apr;16(6):613-5.PMID: 11919171 [PubMed - indexed for MEDLINE]Related articlesFree article

GLUT8 glucose transporter is localized to excitatory and inhibitory neurons in the rat hippocampus.

Reagan LP, Rosell DR, Alves SE, Hoskin EK, McCall AL, Charron MJ, McEwen BS.

Brain Res. 2002 Apr 5;932(1-2):129-34.PMID: 11911870 [PubMed - indexed for MEDLINE]Related articles

Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators.

Joost HG, Bell GI, Best JD, Birnbaum MJ, Charron MJ, Chen YT, Doege H, James DE, Lodish HF, Moley KH, Moley JF, Mueckler M, Rogers S, Schürmann A, Seino S, Thorens B.

Am J Physiol Endocrinol Metab. 2002 Apr;282(4):E974-6.PMID: 11882521 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization.

Combs TP, Wagner JA, Berger J, Doebber T, Wang WJ, Zhang BB, Tanen M, Berg AH, O'Rahilly S, Savage DB, Chatterjee K, Weiss S, Larson PJ, Gottesdiener KM, Gertz BJ, Charron MJ, Scherer PE, Moller DE.

Endocrinology. 2002 Mar;143(3):998-1007.PMID: 11861525 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased muscle fatigability in GLUT-4-deficient mice.

Gorselink M, Drost MR, de Brouwer KF, Schaart G, van Kranenburg GP, Roemen TH, van Bilsen M, Charron MJ, van der Vusse GJ.

Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E348-54.PMID: 11788366 [PubMed - indexed for MEDLINE]Related articlesFree article

GLUT4 ablation in mice results in redistribution of IRAP to the plasma membrane.

Jiang H, Li J, Katz EB, Charron MJ.

Biochem Biophys Res Commun. 2001 Jun 8;284(2):519-25.PMID: 11394912 [PubMed - indexed for MEDLINE]Related articles

Isomer-specific antidiabetic properties of conjugated linoleic acid. Improved glucose tolerance, skeletal muscle insulin action, and UCP-2 gene expression.

Ryder JW, Portocarrero CP, Song XM, Cui L, Yu M, Combatsiaris T, Galuska D, Bauman DE, Barbano DM, Charron MJ, Zierath JR, Houseknecht KL.

Diabetes. 2001 May;50(5):1149-57.PMID: 11334420 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic adaptations in skeletal muscle overexpressing GLUT4: effects on muscle and physical activity.

Tsao TS, Li J, Chang KS, Stenbit AE, Galuska D, Anderson JE, Zierath JR, McCarter RJ, Charron MJ.

FASEB J. 2001 Apr;15(6):958-69.PMID: 11292656 [PubMed - indexed for MEDLINE]Related articlesFree article

Localization and regulation of GLUTx1 glucose transporter in the hippocampus of streptozotocin diabetic rats.

Reagan LP, Gorovits N, Hoskin EK, Alves SE, Katz EB, Grillo CA, Piroli GG, McEwen BS, Charron MJ.

Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2820-5. Epub 2001 Feb 13.PMID: 11226324 [PubMed - indexed for MEDLINE]Related articlesFree article

Preservation of glucose metabolism in hypertrophic GLUT4-null hearts.

Stenbit AE, Katz EB, Chatham JC, Geenen DL, Factor SM, Weiss RG, Tsao TS, Malhotra A, Chacko VP, Ocampo C, Jelicks LA, Charron MJ.

Am J Physiol Heart Circ Physiol. 2000 Jul;279(1):H313-8.PMID: 10899071 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural and functional characterizations of the 5'-flanking region of the mouse glucagon receptor gene: comparison with the rat gene.

Geiger A, Decaux JF, Burcelin R, Le Cam A, Salazar G, Charron MJ, Girard J, Kervran A.

Biochem Biophys Res Commun. 2000 Jun 16;272(3):912-21.PMID: 10860851 [PubMed - indexed for MEDLINE]Related articles

Reduced glucose uptake precedes insulin signaling defects in adipocytes from heterozygous GLUT4 knockout mice.

Li J, Houseknecht KL, Stenbit AE, Katz EB, Charron MJ.

FASEB J. 2000 Jun;14(9):1117-25.PMID: 10834933 [PubMed - indexed for MEDLINE]Related articlesFree article

Amelioration of insulin resistance but not hyperinsulinemia in obese mice overexpressing GLUT4 selectively in skeletal muscle.

Tsao TS, Katz EB, Pommer D, Charron MJ.

Metabolism. 2000 Mar;49(3):340-6.PMID: 10726912 [PubMed - indexed for MEDLINE]Related articles

Postexercise glucose uptake and glycogen synthesis in skeletal muscle from GLUT4-deficient mice.

Ryder JW, Kawano Y, Galuska D, Fahlman R, Wallberg-Henriksson H, Charron MJ, Zierath JR.

FASEB J. 1999 Dec;13(15):2246-56.PMID: 10593872 [PubMed - indexed for MEDLINE]Related articlesFree article

Predominant expression of the mitochondrial dicarboxylate carrier in white adipose tissue.

Das K, Lewis RY, Combatsiaris TP, Lin Y, Shapiro L, Charron MJ, Scherer PE.

Biochem J. 1999 Dec 1;344 Pt 2:313-20.PMID: 10567211 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolism of d-glucose and its pentaacetate ester in muscles and pancreatic islets of GLUT4 null mice.

Ladrière L, Charron MJ, Malaisse WJ.

Biochem Biophys Res Commun. 1999 Nov 2;264(3):855-9.PMID: 10544020 [PubMed - indexed for MEDLINE]Related articles

In vitro analysis of the glucose-transport system in GLUT4-null skeletal muscle.

Ryder JW, Kawano Y, Chibalin AV, Rincón J, Tsao TS, Stenbit AE, Combatsiaris T, Yang J, Holman GD, Charron MJ, Zierath JR.

Biochem J. 1999 Sep 1;342 ( Pt 2):321-8.PMID: 10455018 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute intravenous leptin infusion increases glucose turnover but not skeletal muscle glucose uptake in ob/ob mice.

Burcelin R, Kamohara S, Li J, Tannenbaum GS, Charron MJ, Friedman JM.

Diabetes. 1999 Jun;48(6):1264-9.PMID: 10342814 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of insulin resistance and diabetes in mice heterozygous for GLUT4 ablation by transgenic complementation of GLUT4 in skeletal muscle.

Tsao TS, Stenbit AE, Factor SM, Chen W, Rossetti L, Charron MJ.

Diabetes. 1999 Apr;48(4):775-82.PMID: 10102694 [PubMed - indexed for MEDLINE]Related articlesFree article