PubMed

Duloxetine for the treatment of recurrent major depressive disorder in elderly patients: treatment outcomes in patients with comorbid arthritis.

Wohlreich MM, Sullivan MD, Mallinckrodt CH, Chappell AS, Oakes TM, Watkin JG, Raskin J.

Psychosomatics. 2009 Jul-Aug;50(4):402-12.PMID: 19687181 [PubMed - in process]Related articles

Evaluating the maintenance of effect of duloxetine in patients with diabetic peripheral neuropathic pain.

Skljarevski V, Desaiah D, Zhang Q, Chappell AS, Detke MJ, Gross JL, Ziegler D.

Diabetes Metab Res Rev. 2009 Oct;25(7):623-31.PMID: 19637208 [PubMed - in process]Related articles

Duloxetine, a centrally acting analgesic, in the treatment of patients with osteoarthritis knee pain: a 13-week, randomized, placebo-controlled trial.

Chappell AS, Ossanna MJ, Liu-Seifert H, Iyengar S, Skljarevski V, Li LC, Bennett RM, Collins H.

Pain. 2009 Dec;146(3):253-60. Epub 2009 Jul 21.PMID: 19625125 [PubMed - in process]Related articles

Comparisons of the efficacy and safety of duloxetine for the treatment of fibromyalgia in patients with versus without major depressive disorder.

Arnold LM, Hudson JI, Wang F, Wohlreich MM, Prakash A, Kajdasz DK, Chappell AS.

Clin J Pain. 2009 Jul-Aug;25(6):461-8.PMID: 19542792 [PubMed - indexed for MEDLINE]Related articles

Safety and tolerability of duloxetine in the treatment of patients with fibromyalgia: pooled analysis of data from five clinical trials.

Choy EH, Mease PJ, Kajdasz DK, Wohlreich MM, Crits-Christoph P, Walker DJ, Chappell AS.

Clin Rheumatol. 2009 Sep;28(9):1035-44. Epub 2009 Jun 18.PMID: 19533210 [PubMed - indexed for MEDLINE]Related articlesFree article

A 1-year safety and efficacy study of duloxetine in patients with fibromyalgia.

Chappell AS, Littlejohn G, Kajdasz DK, Scheinberg M, D'Souza DN, Moldofsky H.

Clin J Pain. 2009 Jun;25(5):365-75.PMID: 19454869 [PubMed - indexed for MEDLINE]Related articles

Brain functional changes and duloxetine treatment response in fibromyalgia: a pilot study.

Hunter AM, Leuchter AF, Cook IA, Abrams M, Siegman BE, Furst DE, Chappell AS.

Pain Med. 2009 May-Jun;10(4):730-8. Epub 2009 Apr 22.PMID: 19453962 [PubMed - indexed for MEDLINE]Related articles

Long-Term Safety, Tolerability, and Efficacy of Duloxetine in the Treatment of Fibromyalgia.

Mease PJ, Russell IJ, Kajdasz DK, Wiltse CG, Detke MJ, Wohlreich MM, Walker DJ, Chappell AS.

Semin Arthritis Rheum. 2009 Jan 17. [Epub ahead of print]PMID: 19152958 [PubMed - as supplied by publisher]Related articles

The relationship between antidepressant and analgesic responses: findings from six placebo-controlled trials assessing the efficacy of duloxetine in patients with major depressive disorder.

Fishbain DA, Detke MJ, Wernicke J, Chappell AS, Kajdasz DK.

Curr Med Res Opin. 2008 Sep 30. [Epub ahead of print]PMID: 18828958 [PubMed - as supplied by publisher]Related articles

Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial.

Russell IJ, Mease PJ, Smith TR, Kajdasz DK, Wohlreich MM, Detke MJ, Walker DJ, Chappell AS, Arnold LM.

Pain. 2008 Jun;136(3):432-44. Epub 2008 Apr 18.PMID: 18395345 [PubMed - indexed for MEDLINE]Related articles

Epidemiology, public health burden, and treatment of diabetic peripheral neuropathic pain: a review.

Barrett AM, Lucero MA, Le T, Robinson RL, Dworkin RH, Chappell AS.

Pain Med. 2007 Sep;8 Suppl 2:S50-62. Review.PMID: 17714116 [PubMed - indexed for MEDLINE]Related articles

An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain.

Wernicke JF, Wang F, Pritchett YL, Smith TR, Raskin J, D'Souza DN, Iyengar S, Chappell AS.

Pain Med. 2007 Sep;8(6):503-13.PMID: 17716324 [PubMed - indexed for MEDLINE]Related articles

Duloxetine for the management of diabetic peripheral neuropathic pain: evaluation of functional outcomes.

Armstrong DG, Chappell AS, Le TK, Kajdasz DK, Backonja M, D'Souza DN, Russell JM.

Pain Med. 2007 Jul-Aug;8(5):410-8. Erratum in: Pain Med. 2007 Nov-Dec;8(8):690. PMID: 17661854 [PubMed - indexed for MEDLINE]Related articles

AMPA potentiator treatment of cognitive deficits in Alzheimer disease.

Chappell AS, Gonzales C, Williams J, Witte MM, Mohs RC, Sperling R.

Neurology. 2007 Mar 27;68(13):1008-12.PMID: 17389305 [PubMed - indexed for MEDLINE]Related articles

Impact of disease characteristics on the efficacy of duloxetine in diabetic peripheral neuropathic pain.

Ziegler D, Pritchett YL, Wang F, Desaiah D, Robinson MJ, Hall JA, Chappell AS.

Diabetes Care. 2007 Mar;30(3):664-9.PMID: 17327338 [PubMed - indexed for MEDLINE]Related articlesFree article

Multiple-dose plasma pharmacokinetic and safety study of LY450108 and LY451395 (AMPA receptor potentiators) and their concentration in cerebrospinal fluid in healthy human subjects.

Jhee SS, Chappell AS, Zarotsky V, Moran SV, Rosenthal M, Kim E, Chalon S, Toublanc N, Brandt J, Coutant DE, Ereshefsky L.

J Clin Pharmacol. 2006 Apr;46(4):424-32.PMID: 16554450 [PubMed - indexed for MEDLINE]Related articles

Structural elements required for association of the Saccharomyces cerevisiae telomerase RNA with the Est2 reverse transcriptase.

Chappell AS, Lundblad V.

Mol Cell Biol. 2004 Sep;24(17):7720-36.PMID: 15314178 [PubMed - indexed for MEDLINE]Related articlesFree article

LY293558, a novel AMPA/GluR5 antagonist, is efficacious and well-tolerated in acute migraine.

Sang CN, Ramadan NM, Wallihan RG, Chappell AS, Freitag FG, Smith TR, Silberstein SD, Johnson KW, Phebus LA, Bleakman D, Ornstein PL, Arnold B, Tepper SJ, Vandenhende F.

Cephalalgia. 2004 Jul;24(7):596-602.PMID: 15196302 [PubMed - indexed for MEDLINE]Related articles

A crossover, add-on trial of talampanel in patients with refractory partial seizures.

Chappell AS, Sander JW, Brodie MJ, Chadwick D, Lledo A, Zhang D, Bjerke J, Kiesler GM, Arroyo S.

Neurology. 2002 Jun 11;58(11):1680-2.PMID: 12058100 [PubMed - indexed for MEDLINE]Related articles

Pearls and pitfalls of clinical trial investigation: should I get involved in the drug development process?

Chappell AS.

Semin Neurol. 2001 Dec;21(4):417-24. Review.PMID: 11774057 [PubMed - indexed for MEDLINE]Related articles

Talampanel, a novel noncompetitive AMPA antagonist, is neuroprotective after traumatic brain injury in rats.

Belayev L, Alonso OF, Liu Y, Chappell AS, Zhao W, Ginsberg MD, Busto R.

J Neurotrauma. 2001 Oct;18(10):1031-8.PMID: 11686490 [PubMed - indexed for MEDLINE]Related articles

Effects of the 2-amino-3-hydroxy-5-methyl-4-isoxazole-proprionic acid/kainate antagonist LY293558 on spontaneous and evoked postoperative pain.

Gilron I, Max MB, Lee G, Booher SL, Sang CN, Chappell AS, Dionne RA.

Clin Pharmacol Ther. 2000 Sep;68(3):320-7.PMID: 11014414 [PubMed - indexed for MEDLINE]Related articles

AMPA/kainate antagonist LY293558 reduces capsaicin-evoked hyperalgesia but not pain in normal skin in humans.

Sang CN, Hostetter MP, Gracely RH, Chappell AS, Schoepp DD, Lee G, Whitcup S, Caruso R, Max MB.

Anesthesiology. 1998 Nov;89(5):1060-7.PMID: 9821993 [PubMed - indexed for MEDLINE]Related articlesFree article

Zatosetron, a 5-HT3 receptor antagonist in a multicenter trial for acute migraine.

Chappell AS, Bay JM, Botzum GD, Cohen ML.

Neuropharmacology. 1994 Mar-Apr;33(3-4):509-13.PMID: 7984290 [PubMed - indexed for MEDLINE]Related articles

Visual loss and performance in blind athletes.

Makris VI, Yee RD, Langefeld CD, Chappell AS, Slemenda CW.

Med Sci Sports Exerc. 1993 Feb;25(2):265-9.PMID: 8450731 [PubMed - indexed for MEDLINE]Related articles