PubMed

Nitric oxides mediates a shift from early necrosis to late apoptosis in cytokine-treated {beta}-cells that is associated with irreversible DNA damage.

Hughes KJ, Chambers KT, Meares GP, Corbett JA.

Am J Physiol Endocrinol Metab. 2009 Sep 8. [Epub ahead of print]PMID: 19738038 [PubMed - as supplied by publisher]Related articles

Repair of nitric oxide-damaged DNA in beta-cells requires JNK-dependent GADD45alpha expression.

Hughes KJ, Meares GP, Chambers KT, Corbett JA.

J Biol Chem. 2009 Oct 2;284(40):27402-8. Epub 2009 Aug 2.PMID: 19648647 [PubMed - indexed for MEDLINE]Related articles

Selective mtDNA mutation accumulation results in beta-cell apoptosis and diabetes development.

Bensch KG, Mott JL, Chang SW, Hansen PA, Moxley MA, Chambers KT, de Graaf W, Zassenhaus HP, Corbett JA.

Am J Physiol Endocrinol Metab. 2009 Apr;296(4):E672-80. Epub 2009 Jan 21.PMID: 19158322 [PubMed - indexed for MEDLINE]Related articles

Kappa opioids promote the proliferation of astrocytes via Gbetagamma and beta-arrestin 2-dependent MAPK-mediated pathways.

McLennan GP, Kiss A, Miyatake M, Belcheva MM, Chambers KT, Pozek JJ, Mohabbat Y, Moyer RA, Bohn LM, Coscia CJ.

J Neurochem. 2008 Dec;107(6):1753-65. Epub 2008 Nov 10.PMID: 19014370 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of nitric oxide and the unfolded protein response in cytokine-induced beta-cell death.

Chambers KT, Unverferth JA, Weber SM, Wek RC, Urano F, Corbett JA.

Diabetes. 2008 Jan;57(1):124-32. Epub 2007 Oct 10.PMID: 17928398 [PubMed - indexed for MEDLINE]Related articlesFree article

PGJ2-stimulated beta-cell apoptosis is associated with prolonged UPR activation.

Chambers KT, Weber SM, Corbett JA.

Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1052-61. Epub 2006 Dec 5.PMID: 17148750 [PubMed - indexed for MEDLINE]Related articlesFree article

Posttranslational, translational, and transcriptional responses to nitric oxide stress in Cryptococcus neoformans: implications for virulence.

Missall TA, Pusateri ME, Donlin MJ, Chambers KT, Corbett JA, Lodge JK.

Eukaryot Cell. 2006 Mar;5(3):518-29.PMID: 16524907 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1.

Steer SA, Scarim AL, Chambers KT, Corbett JA.

PLoS Med. 2006 Feb;3(2):e17. Epub 2005 Dec 20.PMID: 16354107 [PubMed - indexed for MEDLINE]Related articlesFree article

PPARgamma ligands induce ER stress in pancreatic beta-cells: ER stress activation results in attenuation of cytokine signaling.

Weber SM, Chambers KT, Bensch KG, Scarim AL, Corbett JA.

Am J Physiol Endocrinol Metab. 2004 Dec;287(6):E1171-7. Epub 2004 Aug 17.PMID: 15315910 [PubMed - indexed for MEDLINE]Related articlesFree article

Recent developments concerning the use of animals in medical research.

Chambers KT, Hines C.

J Leg Med. 1983 Mar;4(1):109-29. No abstract available. PMID: 6602196 [PubMed - indexed for MEDLINE]Related articles