PubMed

Identification of a physiologically relevant endogenous ligand for PPARalpha in liver.

Chakravarthy MV, Lodhi IJ, Yin L, Malapaka RR, Xu HE, Turk J, Semenkovich CF.

Cell. 2009 Aug 7;138(3):476-88. Epub 2009 Jul 30.PMID: 19646743 [PubMed - indexed for MEDLINE]Related articles

Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation.

Chakravarthy MV, Zhu Y, Yin L, Coleman T, Pappan KL, Marshall CA, McDaniel ML, Semenkovich CF.

J Lipid Res. 2009 Apr;50(4):630-40. Epub 2008 Nov 22.PMID: 19029118 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance and atherosclerosis.

Razani B, Chakravarthy MV, Semenkovich CF.

Endocrinol Metab Clin North Am. 2008 Sep;37(3):603-21, viii. Review.PMID: 18775354 [PubMed - indexed for MEDLINE]Related articlesFree article

Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats.

Rector RS, Thyfault JP, Laye MJ, Morris RT, Borengasser SJ, Uptergrove GM, Chakravarthy MV, Booth FW, Ibdah JA.

J Physiol. 2008 Sep 1;586(Pt 17):4241-9. Epub 2008 Jul 10.PMID: 18617560 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased fetal size is associated with beta-cell hyperfunction in early life and failure with age.

Chakravarthy MV, Zhu Y, Wice MB, Coleman T, Pappan KL, Marshall CA, McDaniel ML, Semenkovich CF.

Diabetes. 2008 Oct;57(10):2698-707. Epub 2008 Jun 30.PMID: 18591393 [PubMed - indexed for MEDLINE]Related articlesFree article

Respiratory uncoupling in skeletal muscle delays death and diminishes age-related disease.

Gates AC, Bernal-Mizrachi C, Chinault SL, Feng C, Schneider JG, Coleman T, Malone JP, Townsend RR, Chakravarthy MV, Semenkovich CF.

Cell Metab. 2007 Dec;6(6):497-505.PMID: 18054318 [PubMed - indexed for MEDLINE]Related articles

Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.

Chakravarthy MV, Zhu Y, López M, Yin L, Wozniak DF, Coleman T, Hu Z, Wolfgang M, Vidal-Puig A, Lane MD, Semenkovich CF.

J Clin Invest. 2007 Sep;117(9):2539-52.PMID: 17694178 [PubMed - indexed for MEDLINE]Related articlesFree article

The ABCs of beta-cell dysfunction in type 2 diabetes.

Chakravarthy MV, Semenkovich CF.

Nat Med. 2007 Mar;13(3):241-2. No abstract available. PMID: 17342111 [PubMed - indexed for MEDLINE]Related articles

Physical activity and dietary intervention for chronic diseases: a quick fix after all?

Booth FW, Chakravarthy MV.

J Appl Physiol. 2006 May;100(5):1439-40. No abstract available. PMID: 16614361 [PubMed - indexed for MEDLINE]Related articlesFree article

"New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis.

Chakravarthy MV, Pan Z, Zhu Y, Tordjman K, Schneider JG, Coleman T, Turk J, Semenkovich CF.

Cell Metab. 2005 May;1(5):309-22.PMID: 16054078 [PubMed - indexed for MEDLINE]Related articles

Eating, exercise, and "thrifty" genotypes: connecting the dots toward an evolutionary understanding of modern chronic diseases.

Chakravarthy MV, Booth FW.

J Appl Physiol. 2004 Jan;96(1):3-10. Review.PMID: 14660491 [PubMed - indexed for MEDLINE]Related articlesFree article

Inactivity and inaction: we can't afford either.

Chakravarthy MV, Booth FW.

Arch Pediatr Adolesc Med. 2003 Aug;157(8):731-2. No abstract available. PMID: 12912776 [PubMed - indexed for MEDLINE]Related articles

p27Kip1: a key regulator of skeletal muscle satellite cell proliferation.

Spangenburg EE, Chakravarthy MV, Booth FW.

Clin Orthop Relat Res. 2002 Oct;(403 Suppl):S221-7. Review.PMID: 12394472 [PubMed - indexed for MEDLINE]Related articles

Exercise and gene expression: physiological regulation of the human genome through physical activity.

Booth FW, Chakravarthy MV, Spangenburg EE.

J Physiol. 2002 Sep 1;543(Pt 2):399-411. Review.PMID: 12205177 [PubMed - indexed for MEDLINE]Related articlesFree article

Waging war on physical inactivity: using modern molecular ammunition against an ancient enemy.

Booth FW, Chakravarthy MV, Gordon SE, Spangenburg EE.

J Appl Physiol. 2002 Jul;93(1):3-30. Review.PMID: 12070181 [PubMed - indexed for MEDLINE]Related articlesFree article

The molecular responses of skeletal muscle satellite cells to continuous expression of IGF-1: implications for the rescue of induced muscular atrophy in aged rats.

Chakravarthy MV, Booth FW, Spangenburg EE.

Int J Sport Nutr Exerc Metab. 2001 Dec;11 Suppl:S44-8.PMID: 11915927 [PubMed - indexed for MEDLINE]Related articles

An obligation for primary care physicians to prescribe physical activity to sedentary patients to reduce the risk of chronic health conditions.

Chakravarthy MV, Joyner MJ, Booth FW.

Mayo Clin Proc. 2002 Feb;77(2):165-73. Review.PMID: 11838650 [PubMed - indexed for MEDLINE]Related articlesFree article

Culture in low levels of oxygen enhances in vitro proliferation potential of satellite cells from old skeletal muscles.

Chakravarthy MV, Spangenburg EE, Booth FW.

Cell Mol Life Sci. 2001 Jul;58(8):1150-8.PMID: 11529507 [PubMed - indexed for MEDLINE]Related articles

Long-term insulin-like growth factor-I expression in skeletal muscles attenuates the enhanced in vitro proliferation ability of the resident satellite cells in transgenic mice.

Chakravarthy MV, Fiorotto ML, Schwartz RJ, Booth FW.

Mech Ageing Dev. 2001 Sep;122(12):1303-20.PMID: 11438121 [PubMed - indexed for MEDLINE]Related articles

IGF-I restores satellite cell proliferative potential in immobilized old skeletal muscle.

Chakravarthy MV, Davis BS, Booth FW.

J Appl Physiol. 2000 Oct;89(4):1365-79.PMID: 11007571 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor-I extends in vitro replicative life span of skeletal muscle satellite cells by enhancing G1/S cell cycle progression via the activation of phosphatidylinositol 3'-kinase/Akt signaling pathway.

Chakravarthy MV, Abraha TW, Schwartz RJ, Fiorotto ML, Booth FW.

J Biol Chem. 2000 Nov 17;275(46):35942-52.PMID: 10962000 [PubMed - indexed for MEDLINE]Related articlesFree article