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The beta3-Adrenoceptor Agonist GW427353 (solabegron) Decreases Excitability of Human Enteric Neurons via Release of Somatostatin.

Schemann M, Hafsi N, Michel K, Kober OI, Wollmann J, Li Q, Zeller F, Langer R, Lee K, Cellek S.

Gastroenterology. 2009 Sep 25. [Epub ahead of print]PMID: 19786030 [PubMed - as supplied by publisher]Related articles

GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility.

Sanger GJ, Westaway SM, Barnes AA, Macpherson DT, Muir AI, Jarvie EM, Bolton VN, Cellek S, Näslund E, Hellström PM, Borman RA, Unsworth WP, Matthews KL, Lee K.

Neurogastroenterol Motil. 2009 Jun;21(6):657-64, e30-1.PMID: 19374732 [PubMed - indexed for MEDLINE]Related articles

5-hydroxyindalpine, an agonist at the putative 5-HT receptor, has no activity on human recombinant monoamine receptors but accelerates distension-induced peristalsis in mouse isolated colon.

Mitchell NA, Pepperell E, Ociepka S, Brown JD, Witherington J, Tuladhar B, Sanger GJ, Lee K, Cellek S.

Neurogastroenterol Motil. 2009 Jul;21(7):760-e48. Epub 2009 Mar 2.PMID: 19309442 [PubMed - indexed for MEDLINE]Related articles

Potentiation by cholinesterase inhibitors of cholinergic activity in rat isolated stomach and colon.

Jarvie EM, Cellek S, Sanger GJ.

Pharmacol Res. 2008 Nov-Dec;58(5-6):297-301. Epub 2008 Sep 9.PMID: 18824231 [PubMed - indexed for MEDLINE]Related articles

The investigation of putative agents, using an in vitro model, to prevent cavernosal smooth muscle dysfunction during low-flow priapism.

Muneer A, Cellek S, Ralph DJ, Minhas S.

BJU Int. 2008 Sep;102(8):988-92. Epub 2008 Jun 28.PMID: 18565173 [PubMed - indexed for MEDLINE]Related articles

Synergy between 5-HT4 receptor activation and acetylcholinesterase inhibition in human colon and rat forestomach.

Cellek S, Thangiah R, Jarvie EM, Vivekanandan S, Lalude O, Sanger GJ.

Neurogastroenterol Motil. 2008 May;20(5):539-45. Epub 2008 Jan 10.PMID: 18194150 [PubMed - indexed for MEDLINE]Related articles

Demonstration of functional neuronal beta3-adrenoceptors within the enteric nervous system.

Cellek S, Thangiah R, Bassil AK, Campbell CA, Gray KM, Stretton JL, Lalude O, Vivekanandan S, Wheeldon A, Winchester WJ, Sanger GJ, Schemann M, Lee K.

Gastroenterology. 2007 Jul;133(1):175-83. Epub 2007 May 10. Erratum in: Gastroenterology. 2007 Sep;133(3):1055. PMID: 17631141 [PubMed - indexed for MEDLINE]Related articles

5-HT4 receptor agonists enhance both cholinergic and nitrergic activities in human isolated colon circular muscle.

Cellek S, John AK, Thangiah R, Dass NB, Bassil AK, Jarvie EM, Lalude O, Vivekanandan S, Sanger GJ.

Neurogastroenterol Motil. 2006 Sep;18(9):853-61.PMID: 16918765 [PubMed - indexed for MEDLINE]Related articles

The breakdown of preformed advanced glycation end products reverses erectile dysfunction in streptozotocin-induced diabetic rats: preventive versus curative treatment.

Usta MF, Kendirci M, Gur S, Foxwell NA, Bivalacqua TJ, Cellek S, Hellstrom WJ.

J Sex Med. 2006 Mar;3(2):242-50; discussion 250-2.PMID: 16490017 [PubMed - indexed for MEDLINE]Related articles

Physiology of erectile function.

Sáenz de Tejada I, Angulo J, Cellek S, González-Cadavid N, Heaton J, Pickard R, Simonsen U.

J Sex Med. 2004 Nov;1(3):254-65. Review.PMID: 16422955 [PubMed - indexed for MEDLINE]Related articles

A nitric oxide-releasing PDE5 inhibitor relaxes human corpus cavernosum in the absence of endogenous nitric oxide.

Kalsi JS, Ralph DJ, Thomas P, Bellringer J, Minhas S, Kell PD, Cellek S.

J Sex Med. 2005 Jan;2(1):53-7.PMID: 16422907 [PubMed - indexed for MEDLINE]Related articles

Pathophysiology of erectile dysfunction.

Sáenz de Tejada I, Angulo J, Cellek S, González-Cadavid N, Heaton J, Pickard R, Simonsen U.

J Sex Med. 2005 Jan;2(1):26-39.PMID: 16422902 [PubMed - indexed for MEDLINE]Related articles

Let's make NO mistake!

Cellek S.

Int J Impot Res. 2005 Jul-Aug;17(4):388-9. No abstract available. PMID: 15995720 [PubMed - indexed for MEDLINE]Related articles

Nitrergic neurodegeneration in cerebral arteries of streptozotocin-induced diabetic rats: a new insight into diabetic stroke.

Cellek S, Anderson PN, Foxwell NA.

Diabetes. 2005 Jan;54(1):212-9.PMID: 15616031 [PubMed - indexed for MEDLINE]Related articlesFree article

Point of NO return for nitrergic nerves in diabetes: a new insight into diabetic complications.

Cellek S.

Curr Pharm Des. 2004;10(29):3683-95. Review.PMID: 15579064 [PubMed - indexed for MEDLINE]Related articles

Morphological, chemical and functional analysis of catuaba preparations.

Kletter C, Glasl S, Presser A, Werner I, Reznicek G, Narantuya S, Cellek S, Haslinger E, Jurenitsch J.

Planta Med. 2004 Oct;70(10):993-1000.PMID: 15490329 [PubMed - indexed for MEDLINE]Related articles

RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: a mechanism for diabetes-associated erectile dysfunction.

Bivalacqua TJ, Champion HC, Usta MF, Cellek S, Chitaley K, Webb RC, Lewis RL, Mills TM, Hellstrom WJ, Kadowitz PJ.

Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):9121-6. Epub 2004 Jun 7.PMID: 15184671 [PubMed - indexed for MEDLINE]Related articlesFree article

Investigation of cavernosal smooth muscle dysfunction in low flow priapism using an in vitro model.

Muneer A, Cellek S, Dogan A, Kell PD, Ralph DJ, Minhas S.

Int J Impot Res. 2005 Jan-Feb;17(1):10-8.PMID: 15071490 [PubMed - indexed for MEDLINE]Related articles

A comparative study of sildenafil, NCX-911 and BAY41-2272 on the anococcygeus muscle of diabetic rats.

Kalsi JS, Ralph DJ, Madge DJ, Kell PD, Cellek S.

Int J Impot Res. 2004 Dec;16(6):479-85.PMID: 15029225 [PubMed - indexed for MEDLINE]Related articles

NCX-911, a novel nitric oxide-releasing PDE5 inhibitor relaxes rabbit corpus cavernosum in the absence of endogenous nitric oxide.

Kalsi JS, Kell PD, Cellek S, Ralph DJ.

Int J Impot Res. 2004 Apr;16(2):195-200.PMID: 14961060 [PubMed - indexed for MEDLINE]Related articles

Functional evidence for nitrergic neurotransmission in a human clitoral corpus cavernosum: a case study.

Creighton SM, Crouch NS, Foxwell NA, Cellek S.

Int J Impot Res. 2004 Aug;16(4):319-24.PMID: 14961056 [PubMed - indexed for MEDLINE]Related articles

Synergistic action of advanced glycation end products and endogenous nitric oxide leads to neuronal apoptosis in vitro: a new insight into selective nitrergic neuropathy in diabetes.

Cellek S, Qu W, Schmidt AM, Moncada S.

Diabetologia. 2004 Feb;47(2):331-9. Epub 2003 Dec 16.PMID: 14676945 [PubMed - indexed for MEDLINE]Related articles

Y-27632, a Rho-kinase inhibitor, inhibits proliferation and adrenergic contraction of prostatic smooth muscle cells.

Rees RW, Foxwell NA, Ralph DJ, Kell PD, Moncada S, Cellek S.

J Urol. 2003 Dec;170(6 Pt 1):2517-22.PMID: 14634463 [PubMed - indexed for MEDLINE]Related articles

Two phases of nitrergic neuropathy in streptozotocin-induced diabetic rats.

Cellek S, Foxwell NA, Moncada S.

Diabetes. 2003 Sep;52(9):2353-62.PMID: 12941776 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitrergic-noradrenergic interaction in penile erection: a new insight into erectile dysfunction.

Cellek S.

Drugs Today (Barc). 2000 Feb-Mar;36(2-3):135-46.PMID: 12879111 [PubMed]Related articles

BAY41-2272, a novel nitric oxide independent soluble guanylate cyclase activator, relaxes human and rabbit corpus cavernosum in vitro.

Kalsi JS, Rees RW, Hobbs AJ, Royle M, Kell PD, Ralph DJ, Moncada S, Cellek S.

J Urol. 2003 Feb;169(2):761-6.PMID: 12544359 [PubMed - indexed for MEDLINE]Related articles

The Rho-kinase inhibitor Y-27632 and the soluble guanylyl cyclase activator BAY41-2272 relax rabbit vaginal wall and clitoral corpus cavernosum.

Cellek S.

Br J Pharmacol. 2003 Jan;138(2):287-90.PMID: 12540518 [PubMed - indexed for MEDLINE]Related articlesFree article

A Rho-kinase inhibitor, soluble guanylate cyclase activator and nitric oxide-releasing PDE5 inhibitor: novel approaches to erectile dysfunction.

Cellek S, Rees RW, Kalsi J.

Expert Opin Investig Drugs. 2002 Nov;11(11):1563-73. Review.PMID: 12437503 [PubMed - indexed for MEDLINE]Related articles

Current oral treatments for erectile dysfunction.

Kalsi JS, Cellek S, Muneer A, Kell PD, Ralph DJ, Minhas S.

Expert Opin Pharmacother. 2002 Nov;3(11):1613-29. Review.PMID: 12437495 [PubMed - indexed for MEDLINE]Related articles

Purines and pyrimidines are not involved in NANC relaxant responses in the rabbit vaginal wall.

Ziessen T, Cellek S.

Br J Pharmacol. 2002 Oct;137(4):513-21.PMID: 12359633 [PubMed - indexed for MEDLINE]Related articlesFree article

Hierarchy of membrane-targeting signals of phospholipase D1 involving lipid modification of a pleckstrin homology domain.

Sugars JM, Cellek S, Manifava M, Coadwell J, Ktistakis NT.

J Biol Chem. 2002 Aug 9;277(32):29152-61. Epub 2002 May 20.PMID: 12021265 [PubMed - indexed for MEDLINE]Related articlesFree article

Human and rabbit cavernosal smooth muscle cells express Rho-kinase.

Rees RW, Ziessen T, Ralph DJ, Kell P, Moncada S, Cellek S.

Int J Impot Res. 2002 Feb;14(1):1-7.PMID: 11896471 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the non-nitrergic NANC relaxation responses in the rabbit vaginal wall.

Ziessen T, Moncada S, Cellek S.

Br J Pharmacol. 2002 Jan;135(2):546-54.PMID: 11815390 [PubMed - indexed for MEDLINE]Related articlesFree article

Y-27632, an inhibitor of Rho-kinase, antagonizes noradrenergic contractions in the rabbit and human penile corpus cavernosum.

Rees RW, Ralph DJ, Royle M, Moncada S, Cellek S.

Br J Pharmacol. 2001 Jun;133(4):455-8.PMID: 11399661 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective nitrergic neurodegeneration in diabetes mellitus - a nitric oxide-dependent phenomenon.

Cellek S, Rodrigo J, Lobos E, Fernández P, Serrano J, Moncada S.

Br J Pharmacol. 1999 Dec;128(8):1804-12.PMID: 10588937 [PubMed - indexed for MEDLINE]Related articlesFree article

Visualization of nitric oxide formation in cell cultures and living tissue.

Wiklund NP, Iversen HH, Leone AM, Cellek S, Brundin L, Gustafsson LE, Moncada S.

Acta Physiol Scand. 1999 Oct;167(2):161-6.PMID: 10571552 [PubMed - indexed for MEDLINE]Related articles

Fatty acylation of phospholipase D1 on cysteine residues 240 and 241 determines localization on intracellular membranes.

Sugars JM, Cellek S, Manifava M, Coadwell J, Ktistakis NT.

J Biol Chem. 1999 Oct 15;274(42):30023-7.PMID: 10514487 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitrergic neurotransmission mediates the non-adrenergic non-cholinergic responses in the clitoral corpus cavernosum of the rabbit.

Cellek S, Moncada S.

Br J Pharmacol. 1998 Dec;125(8):1627-9.PMID: 9886752 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitrergic modulation of cholinergic responses in the opossum lower oesophageal sphincter.

Cellek S, Moncada S.

Br J Pharmacol. 1997 Nov;122(6):1043-6.PMID: 9401767 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitrergic control of peripheral sympathetic responses in the human corpus cavernosum: a comparison with other species.

Cellek S, Moncada S.

Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):8226-31.PMID: 9223343 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of noradrenergic responses by nitric oxide from inducible nitric oxide synthase.

Cellek S, Moncada S.

Nitric Oxide. 1997 Jun;1(3):204-10.PMID: 9704581 [PubMed - indexed for MEDLINE]Related articles

Visualisation of nitric oxide released by nerve stimulation.

Wiklund NP, Cellek S, Leone AM, Iversen HH, Gustafsson LE, Brundin L, Furst VW, Flock A, Moncada S.

J Neurosci Res. 1997 Jan 15;47(2):224-32.PMID: 9008153 [PubMed - indexed for MEDLINE]Related articles

Regulation of the cardiovascular system by non-adrenergic non-cholinergic nerves.

Ahluwalia A, Cellek S.

Curr Opin Nephrol Hypertens. 1997 Jan;6(1):74-9. Review.PMID: 9051358 [PubMed - indexed for MEDLINE]Related articles

Inhibition of nitrergic relaxations by a selective inhibitor of the soluble guanylate cyclase.

Cellek S, Kasakov L, Moncada S.

Br J Pharmacol. 1996 May;118(1):137-40.PMID: 8733586 [PubMed - indexed for MEDLINE]Related articlesFree article

Visualisation of nitric oxide generated by activated murine macrophages.

Leone AM, Furst VW, Foxwell NA, Cellek S, Moncada S.

Biochem Biophys Res Commun. 1996 Apr 5;221(1):37-41.PMID: 8660339 [PubMed - indexed for MEDLINE]Related articles

cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase.

Moro MA, Russel RJ, Cellek S, Lizasoain I, Su Y, Darley-Usmar VM, Radomski MW, Moncada S.

Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1480-5.PMID: 8643658 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of nitrergic neurotransmission during short- and long-term electrical stimulation of the rabbit anococcygeus muscle.

Kasakov L, Cellek S, Moncada S.

Br J Pharmacol. 1995 Aug;115(7):1149-54.PMID: 7582537 [PubMed - indexed for MEDLINE]Related articlesFree article

Dexamethasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone: an insight into endotoxin shock.

Rees DD, Cellek S, Palmer RM, Moncada S.

Biochem Biophys Res Commun. 1990 Dec 14;173(2):541-7.PMID: 1701990 [PubMed - indexed for MEDLINE]Related articles

Cholesterol feeding attenuates endothelium-dependent relaxation response to acetylcholine in the main pulmonary artery of chickens.

Aksulu HE, Cellek S, Türker RK.

Eur J Pharmacol. 1986 Oct 7;129(3):397-400.PMID: 3780851 [PubMed - indexed for MEDLINE]Related articles