My NCBI | Sign In
RSS Settings
  • Search: Cavener DR[au]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

    Results: 1 to 50 of 67

    1.

    GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent L-asparaginase.

    Bunpo P, Dudley A, Cundiff JK, Cavener DR, Wek RC, Anthony TG.

    J Biol Chem. 2009 Nov 20;284(47):32742-9. Epub 2009 Sep 25.PMID: 19783659 [PubMed - in process]Related articles

    2.

    Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation.

    Feng D, Wei J, Gupta S, McGrath BC, Cavener DR.

    BMC Cell Biol. 2009 Sep 4;10:61.PMID: 19732428 [PubMed - in process]Related articlesFree article

    3.

    eIF2{alpha} kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver.

    Dang Do AN, Kimball SR, Cavener DR, Jefferson LS.

    Physiol Genomics. 2009 Aug 7;38(3):328-41. Epub 2009 Jun 9.PMID: 19509078 [PubMed - in process]Related articles

    4.

    Sleeping Beauty, awake! Regulation of insulin gene expression by methylation of histone H3.

    Cavener DR.

    Diabetes. 2009 Jan;58(1):28-9. No abstract available. PMID: 19114729 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation.

    Bobrovnikova-Marjon E, Hatzivassiliou G, Grigoriadou C, Romero M, Cavener DR, Thompson CB, Diehl JA.

    Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16314-9. Epub 2008 Oct 13.PMID: 18852460 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    PERK is essential for neonatal skeletal development to regulate osteoblast proliferation and differentiation.

    Wei J, Sheng X, Feng D, McGrath B, Cavener DR.

    J Cell Physiol. 2008 Dec;217(3):693-707.PMID: 18683826 [PubMed - indexed for MEDLINE]Related articles

    7.

    Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis.

    Kimball SR, Do AN, Kutzler L, Cavener DR, Jefferson LS.

    J Biol Chem. 2008 Feb 8;283(6):3465-75. Epub 2007 Dec 10.PMID: 18070882 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Translational control and the unfolded protein response.

    Wek RC, Cavener DR.

    Antioxid Redox Signal. 2007 Dec;9(12):2357-71. Review.PMID: 17760508 [PubMed - indexed for MEDLINE]Related articles

    9.

    PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice.

    Iida K, Li Y, McGrath BC, Frank A, Cavener DR.

    BMC Cell Biol. 2007 Aug 29;8:38.PMID: 17727724 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Expansion and evolution of insect GMC oxidoreductases.

    Iida K, Cox-Foster DL, Yang X, Ko WY, Cavener DR.

    BMC Evol Biol. 2007 May 11;7:75.PMID: 17498303 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid.

    Guo F, Cavener DR.

    Cell Metab. 2007 Feb;5(2):103-14.PMID: 17276353 [PubMed - indexed for MEDLINE]Related articles

    12.

    Tryptophan catabolism generates autoimmune-preventive regulatory T cells.

    Fallarino F, Grohmann U, You S, McGrath BC, Cavener DR, Vacca C, Orabona C, Bianchi R, Belladonna ML, Volpi C, Fioretti MC, Puccetti P.

    Transpl Immunol. 2006 Dec;17(1):58-60. Epub 2006 Oct 10.PMID: 17157218 [PubMed - indexed for MEDLINE]Related articles

    13.

    PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.

    Zhang W, Feng D, Li Y, Iida K, McGrath B, Cavener DR.

    Cell Metab. 2006 Dec;4(6):491-7.PMID: 17141632 [PubMed - indexed for MEDLINE]Related articles

    14.

    Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism.

    Senée V, Chelala C, Duchatelet S, Feng D, Blanc H, Cossec JC, Charon C, Nicolino M, Boileau P, Cavener DR, Bougnères P, Taha D, Julier C.

    Nat Genet. 2006 Jun;38(6):682-7. Epub 2006 May 21.PMID: 16715098 [PubMed - indexed for MEDLINE]Related articles

    15.

    The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells.

    Fallarino F, Grohmann U, You S, McGrath BC, Cavener DR, Vacca C, Orabona C, Bianchi R, Belladonna ML, Volpi C, Santamaria P, Fioretti MC, Puccetti P.

    J Immunol. 2006 Jun 1;176(11):6752-61.PMID: 16709834 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis.

    Liang SH, Zhang W, McGrath BC, Zhang P, Cavener DR.

    Biochem J. 2006 Jan 1;393(Pt 1):201-9.PMID: 16124869 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    PERK is responsible for the increased phosphorylation of eIF2alpha and the severe inhibition of protein synthesis after transient global brain ischemia.

    Owen CR, Kumar R, Zhang P, McGrath BC, Cavener DR, Krause GS.

    J Neurochem. 2005 Sep;94(5):1235-42. Epub 2005 Jul 5.PMID: 16000157 [PubMed - indexed for MEDLINE]Related articles

    18.

    Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex.

    Hao S, Sharp JW, Ross-Inta CM, McDaniel BJ, Anthony TG, Wek RC, Cavener DR, McGrath BC, Rudell JB, Koehnle TJ, Gietzen DW.

    Science. 2005 Mar 18;307(5716):1776-8.PMID: 15774759 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.

    Anthony TG, McDaniel BJ, Byerley RL, McGrath BC, Cavener DR, McNurlan MA, Wek RC.

    J Biol Chem. 2004 Aug 27;279(35):36553-61. Epub 2004 Jun 22.PMID: 15213227 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response.

    Jiang HY, Wek SA, McGrath BC, Lu D, Hai T, Harding HP, Wang X, Ron D, Cavener DR, Wek RC.

    Mol Cell Biol. 2004 Feb;24(3):1365-77.PMID: 14729979 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Glucose dehydrogenase is required for normal sperm storage and utilization in female Drosophila melanogaster.

    Iida K, Cavener DR.

    J Exp Biol. 2004 Feb;207(Pt 4):675-81.PMID: 14718510 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses.

    Jiang HY, Wek SA, McGrath BC, Scheuner D, Kaufman RJ, Cavener DR, Wek RC.

    Mol Cell Biol. 2003 Aug;23(16):5651-63.PMID: 12897138 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    PERK eIF2alpha kinase regulates neonatal growth by controlling the expression of circulating insulin-like growth factor-I derived from the liver.

    Li Y, Iida K, O'Neil J, Zhang P, Li S, Frank A, Gabai A, Zambito F, Liang SH, Rosen CJ, Cavener DR.

    Endocrinology. 2003 Aug;144(8):3505-13.PMID: 12865332 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice.

    Zhang P, McGrath BC, Reinert J, Olsen DS, Lei L, Gill S, Wek SA, Vattem KM, Wek RC, Kimball SR, Jefferson LS, Cavener DR.

    Mol Cell Biol. 2002 Oct;22(19):6681-8.PMID: 12215525 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas.

    Zhang P, McGrath B, Li S, Frank A, Zambito F, Reinert J, Gannon M, Ma K, McNaughton K, Cavener DR.

    Mol Cell Biol. 2002 Jun;22(11):3864-74.PMID: 11997520 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    New ways of initiating translation in eukaryotes.

    Schneider R, Agol VI, Andino R, Bayard F, Cavener DR, Chappell SA, Chen JJ, Darlix JL, Dasgupta A, Donzé O, Duncan R, Elroy-Stein O, Farabaugh PJ, Filipowicz W, Gale M Jr, Gehrke L, Goldman E, Groner Y, Harford JB, Hatzglou M, He B, Hellen CU, Hentze MW, Hershey J, Hershey P, Hohn T, Holcik M, Hunter CP, Igarashi K, Jackson R, Jagus R, Jefferson LS, Joshi B, Kaempfer R, Katze M, Kaufman RJ, Kiledjian M, Kimball SR, Kimchi A, Kirkegaard K, Koromilas AE, Krug RM, Kruys V, Lamphear BJ, Lemon S, Lloyd RE, Maquat LE, Martinez-Salas E, Mathews MB, Mauro VP, Miyamoto S, Mohr I, Morris DR, Moss EG, Nakashima N, Palmenberg A, Parkin NT, Pe'ery T, Pelletier J, Peltz S, Pestova TV, Pilipenko EV, Prats AC, Racaniello V, Read GS, Rhoads RE, Richter JD, Rivera-Pomar R, Rouault T, Sachs A, Sarnow P, Scheper GC, Schiff L, Schoenberg DR, Semler BL, Siddiqui A, Skern T, Sonenberg N, Sossin W, Standart N, Tahara SM, Thomas AA, Toulmé JJ, Wilusz J, Wimmer E, Witherell G, Wormington M.

    Mol Cell Biol. 2001 Dec;21(23):8238-46. No abstract available. PMID: 11710333 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.

    Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK.

    Kumar R, Azam S, Sullivan JM, Owen C, Cavener DR, Zhang P, Ron D, Harding HP, Chen JJ, Han A, White BC, Krause GS, DeGracia DJ.

    J Neurochem. 2001 Jun;77(5):1418-21.PMID: 11389192 [PubMed - indexed for MEDLINE]Related articles

    28.

    Complex organization of promoter and enhancer elements regulate the tissue- and developmental stage-specific expression of the Drosophila melanogaster Gld gene.

    Keplinger BL, Guo X, Quine J, Feng Y, Cavener DR.

    Genetics. 2001 Feb;157(2):699-716.PMID: 11156990 [PubMed - indexed for MEDLINE]Related articlesFree article

    29.

    A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha.

    Sood R, Porter AC, Olsen DA, Cavener DR, Wek RC.

    Genetics. 2000 Feb;154(2):787-801.PMID: 10655230 [PubMed - indexed for MEDLINE]Related articlesFree article

    30.

    Isolation of the gene encoding the Drosophila melanogaster homolog of the Saccharomyces cerevisiae GCN2 eIF-2alpha kinase.

    Olsen DS, Jordan B, Chen D, Wek RC, Cavener DR.

    Genetics. 1998 Jul;149(3):1495-509.PMID: 9649537 [PubMed - indexed for MEDLINE]Related articlesFree article

    31.

    Ultrabithorax and Antennapedia 5' untranslated regions promote developmentally regulated internal translation initiation.

    Ye X, Fong P, Iizuka N, Choate D, Cavener DR.

    Mol Cell Biol. 1997 Mar;17(3):1714-21.PMID: 9032298 [PubMed - indexed for MEDLINE]Related articlesFree article

    32.

    Mutations at the Ser50 residue of translation factor eIF-2alpha dominantly affect developmental rate, body weight, and viability of Drosophila melanogaster.

    Qu S, Perlaky SE, Organ EL, Crawford D, Cavener DR.

    Gene Expr. 1997;6(6):349-60.PMID: 9495316 [PubMed - indexed for MEDLINE]Related articles

    33.

    A somatic reproductive organ enhancer complex activates expression in both the developing and the mature Drosophila reproductive tract.

    Keplinger BL, Rabetoy AL, Cavener DR.

    Dev Biol. 1996 Nov 25;180(1):311-23.PMID: 8948593 [PubMed - indexed for MEDLINE]Related articles

    34.

    Heat shock effects on phosphorylation of protein synthesis initiation factor proteins eIF-4E and eIF-2 alpha in Drosophila.

    Duncan RF, Cavener DR, Qu S.

    Biochemistry. 1995 Mar 7;34(9):2985-97.PMID: 7893711 [PubMed - indexed for MEDLINE]Related articles

    35.

    Isolation and characterization of the Drosophila melanogaster gene encoding translation-initiation factor eIF-2 beta.

    Ye X, Cavener DR.

    Gene. 1994 May 16;142(2):271-4.PMID: 8194763 [PubMed - indexed for MEDLINE]Related articles

    36.

    An evolutionarily conserved palindrome in the Drosophila Gld promoter directs tissue-specific expression.

    Gunaratne P, Ross JL, Zhang Q, Organ EL, Cavener DR.

    Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2738-42.PMID: 8146184 [PubMed - indexed for MEDLINE]Related articlesFree article

    37.

    Isolation and characterization of the Drosophila melanogaster eIF-2 alpha gene encoding the alpha subunit of translation initiation factor eIF-2.

    Qu S, Cavener DR.

    Gene. 1994 Mar 25;140(2):239-42.PMID: 8144032 [PubMed - indexed for MEDLINE]Related articles

    38.

    Correlated evolution of the cis-acting regulatory elements and developmental expression of the Drosophila Gld gene in seven species from the subgroup melanogaster.

    Ross JL, Fong PP, Cavener DR.

    Dev Genet. 1994;15(1):38-50.PMID: 8187349 [PubMed - indexed for MEDLINE]Related articles

    39.

    Tissue-specific regulatory elements of the Drosophila Gld gene.

    Quine JA, Gunaratne P, Organ EL, Cavener BA, Cavener DR.

    Mech Dev. 1993 Jul;42(1-2):3-13.PMID: 8369222 [PubMed - indexed for MEDLINE]Related articles

    40.

    Evolution of the expression of the Gld gene in the reproductive tract of Drosophila.

    Schiff NM, Feng Y, Quine JA, Krasney PA, Cavener DR.

    Mol Biol Evol. 1992 Nov;9(6):1029-49.PMID: 1435233 [PubMed - indexed for MEDLINE]Related articles

    41.

    The Drosophila melanogaster stranded at second (sas) gene encodes a putative epidermal cell surface receptor required for larval development.

    Schonbaum CP, Organ EL, Qu S, Cavener DR.

    Dev Biol. 1992 Jun;151(2):431-45.PMID: 1339334 [PubMed - indexed for MEDLINE]Related articles

    42.

    Transgenic animal studies on the evolution of genetic regulatory circuitries.

    Cavener DR.

    Bioessays. 1992 Apr;14(4):237-44. Review.PMID: 1596273 [PubMed - indexed for MEDLINE]Related articles

    43.

    GMC oxidoreductases. A newly defined family of homologous proteins with diverse catalytic activities.

    Cavener DR.

    J Mol Biol. 1992 Feb 5;223(3):811-4.PMID: 1542121 [PubMed - indexed for MEDLINE]Related articles

    44.

    Analysis of the PvuII restriction fragment-length polymorphism and exon structure of the estrogen receptor gene in breast cancer and peripheral blood.

    Yaich L, Dupont WD, Cavener DR, Parl FF.

    Cancer Res. 1992 Jan 1;52(1):77-83.PMID: 1345763 [PubMed - indexed for MEDLINE]Related articlesFree article

    45.

    Organ-specific patterns of gene expression in the reproductive tract of Drosophila are regulated by the sex-determination genes.

    Feng Y, Schiff NM, Cavener DR.

    Dev Biol. 1991 Aug;146(2):451-60.PMID: 1907583 [PubMed - indexed for MEDLINE]Related articles

    46.

    Binding analysis of the estrogen receptor to its specific DNA target site in human breast cancer.

    Foster BD, Cavener DR, Parl FF.

    Cancer Res. 1991 Jul 1;51(13):3405-10.PMID: 2054780 [PubMed - indexed for MEDLINE]Related articlesFree article

    47.

    Eukaryotic start and stop translation sites.

    Cavener DR, Ray SC.

    Nucleic Acids Res. 1991 Jun 25;19(12):3185-92.PMID: 1905801 [PubMed - indexed for MEDLINE]Related articlesFree article

    48.

    Translation initiation in Drosophila melanogaster is reduced by mutations upstream of the AUG initiator codon.

    Feng Y, Gunter LE, Organ EL, Cavener DR.

    Mol Cell Biol. 1991 Apr;11(4):2149-53.PMID: 1900921 [PubMed - indexed for MEDLINE]Related articlesFree article

    49.

    Drosophila glucose dehydrogenase and yeast alcohol oxidase are homologous and share N-terminal homology with other flavoenzymes.

    Cavener DR, Krasney PA.

    Mol Biol Evol. 1991 Jan;8(1):144-50. No abstract available. PMID: 2002763 [PubMed - indexed for MEDLINE]Related articles

    50.

    Developmental expression of the glucose dehydrogenase gene in Drosophila melanogaster.

    Cox-Foster DL, Schonbaum CP, Murtha MT, Cavener DR.

    Genetics. 1990 Apr;124(4):873-80.PMID: 2108903 [PubMed - indexed for MEDLINE]Related articlesFree article

    Supplemental Content

    Filter your results:

    26 free full-text articles in PubMed Central

    Find related data

    Search details

    » See more...

    Recent activity