PubMed

Increased oxidative stress levels and normal antioxidant enzyme activity in circulating mononuclear cells from patients of familial hypercholesterolemia.

Real JT, Martínez-Hervás S, Tormos MC, Domenech E, Pallardó FV, Sáez-Tormo G, Redon J, Carmena R, Chaves FJ, Ascaso JF, García-García AB.

Metabolism. 2009 Sep 30. [Epub ahead of print]PMID: 19800085 [PubMed - as supplied by publisher]Related articles

Increased plasma xanthine oxidase activity is related to nuclear factor kappa beta activation and inflammatory markers in familial combined hyperlipidemia.

Martinez-Hervas S, Real JT, Ivorra C, Priego A, Chaves FJ, Pallardo FV, Viña JR, Redon J, Carmena R, Ascaso JF.

Nutr Metab Cardiovasc Dis. 2009 Sep 16. [Epub ahead of print]PMID: 19765958 [PubMed - as supplied by publisher]Related articles

Clinical review: impact of statin substitution policies on patient outcomes.

Atar D, Carmena R, Clemmensen P, K-Laflamme A, Wassmann S, Lansberg P, Hobbs R.

Ann Med. 2009;41(4):242-56. Review.PMID: 19191052 [PubMed - indexed for MEDLINE]Related articles

Cost-effectiveness of intensive atorvastatin therapy in secondary cardiovascular prevention in the United Kingdom, Spain, and Germany, based on the Treating to New Targets study.

Taylor DC, Pandya A, Thompson D, Chu P, Graff J, Shepherd J, Wenger N, Greten H, Carmena R, Drummond M, Weinstein MC.

Eur J Health Econ. 2009 Jul;10(3):255-65. Epub 2008 Sep 18.PMID: 18800232 [PubMed - indexed for MEDLINE]Related articles

Intensive lipid lowering with atorvastatin in patients with coronary artery disease, diabetes, and chronic kidney disease.

Shepherd J, Kastelein JP, Bittner VA, Carmena R, Deedwania PC, Breazna A, Dobson S, Wilson DJ, Zuckerman AL, Wenger NK; Treating to New Targets Steering Committee and Investigators.

Mayo Clin Proc. 2008 Aug;83(8):870-9.PMID: 18674471 [PubMed - indexed for MEDLINE]Related articlesFree article

A comparison of schizophrenia outpatients treated with antipsychotics with and without metabolic syndrome: findings from the CLAMORS study.

Arango C, Bobes J, Aranda P, Carmena R, Garcia-Garcia M, Rejas J; CLAMORS Study Collaborative Group.

Schizophr Res. 2008 Sep;104(1-3):1-12. Epub 2008 Jul 7.PMID: 18606526 [PubMed - indexed for MEDLINE]Related articles

A new PCSK9 gene promoter variant affects gene expression and causes autosomal dominant hypercholesterolemia.

Blesa S, Vernia S, Garcia-Garcia AB, Martinez-Hervas S, Ivorra C, Gonzalez-Albert V, Ascaso JF, Martín-Escudero JC, Real JT, Carmena R, Casado M, Chaves FJ.

J Clin Endocrinol Metab. 2008 Sep;93(9):3577-83. Epub 2008 Jun 17. Erratum in: J Clin Endocrinol Metab. 2009 Jan;94(1):325. PMID: 18559913 [PubMed - indexed for MEDLINE]Related articlesFree article

Classical cardiovascular risk factors according to fasting plasma glucose levels.

Martinez-Hervas S, Romero P, Hevilla EB, Real JT, Priego A, Martin-Moreno JM, Carmena R, Ascaso JF.

Eur J Intern Med. 2008 May;19(3):209-13. Epub 2007 Nov 8.PMID: 18395166 [PubMed - indexed for MEDLINE]Related articles

Evaluation of clinical diagnosis criteria of familial ligand defective apoB 100 and lipoprotein phenotype comparison between LDL receptor gene mutations affecting ligand-binding domain and the R3500Q mutation of the apoB gene in patients from a South European population.

Ejarque I, Real JT, Martinez-Hervas S, Chaves FJ, Blesa S, Garcia-Garcia AB, Millan E, Ascaso JF, Carmena R.

Transl Res. 2008 Mar;151(3):162-7. Epub 2008 Jan 7.PMID: 18279815 [PubMed - indexed for MEDLINE]Related articles

[Difficult treatment of amiodarone-induced thyrotoxicosis: a case report]

Pedro T, Martínez-Hervás S, Lorente R, Catalá M, Ortega J, Real JT, Carmena R.

An Med Interna. 2007 Nov;24(11):543-6. Spanish. PMID: 18275264 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance and oxidative stress in familial combined hyperlipidemia.

Martinez-Hervas S, Fandos M, Real JT, Espinosa O, Chaves FJ, Saez GT, Salvador A, Cerdá C, Carmena R, Ascaso JF.

Atherosclerosis. 2008 Aug;199(2):384-9. Epub 2007 Dec 31.PMID: 18164710 [PubMed - indexed for MEDLINE]Related articles

Concordance of standard and modified NCEP ATP III criteria for identification of metabolic syndrome in outpatients with schizophrenia treated with antipsychotics: a corollary from the CLAMORS study.

Rejas J, Bobes J, Arango C, Aranda P, Carmena R, Garcia-Garcia M.

Schizophr Res. 2008 Feb;99(1-3):23-8. Epub 2007 Dec 11.PMID: 18063343 [PubMed - indexed for MEDLINE]Related articles

[New targets in patients with cardiometabolic risk]

Ruilope LM, Carmena R.

Med Clin (Barc). 2007 Oct 27;129(15):576-7. Review. Spanish. No abstract available. PMID: 17988615 [PubMed - indexed for MEDLINE]Related articles

Retinoids induce MMP-9 expression through RARalpha during mammary gland remodeling.

Zaragozá R, Gimeno A, Miralles VJ, García-Trevijano ER, Carmena R, García C, Mata M, Puertes IR, Torres L, Viña JR.

Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1140-8. Epub 2006 Dec 12.PMID: 17164434 [PubMed - indexed for MEDLINE]Related articlesFree article

[Familial combined hyperlipidemia, metabolic syndrome and cardiovascular disease]

Martinez-Hervás S, Real JT, Priego A, Sanz J, Martín JM, Carmena R, Ascaso JF.

Rev Esp Cardiol. 2006 Nov;59(11):1195-8. Spanish. PMID: 17144994 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiovascular and metabolic risk in outpatients with schizophrenia treated with antipsychotics: results of the CLAMORS Study.

Bobes J, Arango C, Aranda P, Carmena R, Garcia-Garcia M, Rejas J; CLAMORS Study Collaborative Group.

Schizophr Res. 2007 Feb;90(1-3):162-73. Epub 2006 Nov 21.PMID: 17123783 [PubMed - indexed for MEDLINE]Related articles

[Role of atherogenic dyslipidemia in the development of metabolic syndrome]

Real JT, Romero P, Martínez Hervas S, Pedro T, Carmena R, Ascaso JF.

Med Clin (Barc). 2006 Sep 9;127(9):321-4. Spanish. PMID: 16987450 [PubMed - indexed for MEDLINE]Related articles

Reduction of low-density lipoprotein cholesterol in patients with coronary heart disease and metabolic syndrome: analysis of the Treating to New Targets study.

Deedwania P, Barter P, Carmena R, Fruchart JC, Grundy SM, Haffner S, Kastelein JJ, LaRosa JC, Schachner H, Shepherd J, Waters DD; Treating to New Targets Investigators.

Lancet. 2006 Sep 9;368(9539):919-28.PMID: 16962881 [PubMed - indexed for MEDLINE]Related articles

Semiquantitative multiplex PCR: a useful tool for large rearrangement screening and characterization.

Garcia-Garcia AB, Blesa S, Martinez-Hervas S, Mansego ML, Gonzalez-Albert V, Ascaso JF, Carmena R, Real JT, Chaves FJ.

Hum Mutat. 2006 Aug;27(8):822-8.PMID: 16791839 [PubMed - indexed for MEDLINE]Related articles

[Effect of gender and obesity on postprandial lipemia in non-diabetic normolipidemic subjects and subjects with familial combined hyperlipidemia]

Bartual A, González C, Martínez Hervás S, Real JT, García García AB, Castro Cabezas M, Chaves FJ, Priego MA, Ascaso JF, Carmena R.

Rev Clin Esp. 2006 May;206(5):213-9. Spanish. PMID: 16750103 [PubMed - indexed for MEDLINE]Related articles

Effect of lowering LDL cholesterol substantially below currently recommended levels in patients with coronary heart disease and diabetes: the Treating to New Targets (TNT) study.

Shepherd J, Barter P, Carmena R, Deedwania P, Fruchart JC, Haffner S, Hsia J, Breazna A, LaRosa J, Grundy S, Waters D.

Diabetes Care. 2006 Jun;29(6):1220-6.PMID: 16731999 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of sequence variations in the LDL receptor gene in Spain: general gene screening or search for specific alterations?

Blesa S, Garcia-Garcia AB, Martinez-Hervas S, Mansego ML, Gonzalez-Albert V, Ascaso JF, Carmena R, Real JT, Chaves FJ.

Clin Chem. 2006 Jun;52(6):1021-5. Epub 2006 Apr 20.PMID: 16627557 [PubMed - indexed for MEDLINE]Related articlesFree article

Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/ten-country panel.

Barter PJ, Ballantyne CM, Carmena R, Castro Cabezas M, Chapman MJ, Couture P, de Graaf J, Durrington PN, Faergeman O, Frohlich J, Furberg CD, Gagne C, Haffner SM, Humphries SE, Jungner I, Krauss RM, Kwiterovich P, Marcovina S, Packard CJ, Pearson TA, Reddy KS, Rosenson R, Sarrafzadegan N, Sniderman AD, Stalenhoef AF, Stein E, Talmud PJ, Tonkin AM, Walldius G, Williams KM.

J Intern Med. 2006 Mar;259(3):247-58.PMID: 16476102 [PubMed - indexed for MEDLINE]Related articles

Effects of a controlled program of moderate physical exercise on insulin sensitivity in nonobese, nondiabetic subjects.

Hasbum B, Real JT, Sánchez C, Priego MA, Díaz J, Viguer A, Basanta M, Martínez-Valls J, Marín J, Carmena R, Ascaso JF.

Clin J Sport Med. 2006 Jan;16(1):46-50.PMID: 16377975 [PubMed - indexed for MEDLINE]Related articles

A case of lipoatrophy with insulin glargine: long-acting insulin analogs are not exempt from this complication.

Ampudia-Blasco FJ, Girbes J, Carmena R.

Diabetes Care. 2005 Dec;28(12):2983. No abstract available. PMID: 16306570 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 2 diabetes, dyslipidemia, and vascular risk: rationale and evidence for correcting the lipid imbalance.

Carmena R.

Am Heart J. 2005 Nov;150(5):859-70. Review.PMID: 16290951 [PubMed - indexed for MEDLINE]Related articles

Role of GSH in the modulation of NOS-2 expression in the weaned mammary gland.

Zaragozá R, García-Trevijano ER, Miralles VJ, Mata M, García C, Carmena R, Barber T, Pallardó FV, Torres L, Viña JR.

Biochem Soc Trans. 2005 Dec;33(Pt 6):1397-8. Review.PMID: 16246128 [PubMed - indexed for MEDLINE]Related articles

[Determinants of postprandial lipemia measured as diurnal triglyceride profile in non diabetic normolipidemic subjects]

González C, Real JT, Bartual A, Chaves FJ, García-García AB, Blesa S, Castro-Cabezas M, Ascaso JF, Carmena R.

Med Clin (Barc). 2005 Oct 8;125(12):448-52. Spanish. PMID: 16216199 [PubMed - indexed for MEDLINE]Related articles

Weaning induces NOS-2 expression through NF-kappaB modulation in the lactating mammary gland: importance of GSH.

Zaragozá R, Miralles VJ, Rus AD, García C, Carmena R, García-Trevijano ER, Barber T, Pallardó FV, Torres L, Viña JR.

Biochem J. 2005 Nov 1;391(Pt 3):581-8.PMID: 15954866 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of marathon running on plasma total homocysteine concentrations.

Real JT, Merchante A, Gómez JL, Chaves FJ, Ascaso JF, Carmena R.

Nutr Metab Cardiovasc Dis. 2005 Apr;15(2):134-9. Epub 2005 Apr 13.PMID: 15871862 [PubMed - indexed for MEDLINE]Related articles

Influence of microsomal triglyceride transfer protein promoter polymorphism -493 GT on fasting plasma triglyceride values and interaction with treatment response to atorvastatin in subjects with heterozygous familial hypercholesterolaemia.

García-García AB, González C, Real JT, Martín de Llano JJ, González-Albert V, Civera M, Chaves FJ, Ascaso JF, Carmena R.

Pharmacogenet Genomics. 2005 Apr;15(4):211-8.PMID: 15864113 [PubMed - indexed for MEDLINE]Related articles

Statins and diabetes.

Carmena R, Betteridge DJ.

Semin Vasc Med. 2004 Nov;4(4):321-32. Review.PMID: 15861314 [PubMed - indexed for MEDLINE]Related articles

[Relevance of metabolic syndrome and its definition depending on the criteria employed]

Real JT, Carmena R.

Med Clin (Barc). 2005 Mar 19;124(10):376-8. Spanish. No abstract available. PMID: 15766509 [PubMed - indexed for MEDLINE]Related articles

Daylong triglyceridaemia in healthy Mediterranean and northern European subjects.

van Oostrom AJ, Real JT, Carmena R, Ascaso JF, Castro Cabezas M.

Neth J Med. 2004 Sep;62(8):279-85.PMID: 15588068 [PubMed - indexed for MEDLINE]Related articlesFree article

[Clinical and biochemical characteristics of familial ligand-defective apo B-100 in a South European population]

Ejarque I, Real JT, Chaves FJ, Blesa S, González V, Milian E, Ascaso JF, Priego MA, Carmena R.

Med Clin (Barc). 2004 Oct 9;123(12):456-9. Spanish. PMID: 15498441 [PubMed - indexed for MEDLINE]Related articles

[Plasma lipoprotein (a) values in familial defective ligand apo B 100 in a South European population]

Ejarque I, Leal JT, Ascaso JF, Chaves FJ, Milian E, Priego MA, Carmena R.

An Med Interna. 2004 Jul;21(7):322-5. Spanish. PMID: 15347236 [PubMed - indexed for MEDLINE]Related articles

Atherogenic lipoprotein particles in atherosclerosis.

Carmena R, Duriez P, Fruchart JC.

Circulation. 2004 Jun 15;109(23 Suppl 1):III2-7. Review.PMID: 15198959 [PubMed - indexed for MEDLINE]Related articlesFree article

[Diabetes type 2: the misunderstood disease]

Real JT, Carmena R.

Rev Clin Esp. 2004 Jan;204(1):1-2. Spanish. No abstract available. PMID: 14746752 [PubMed - indexed for MEDLINE]Related articles

Diagnosing insulin resistance by simple quantitative methods in subjects with normal glucose metabolism.

Ascaso JF, Pardo S, Real JT, Lorente RI, Priego A, Carmena R.

Diabetes Care. 2003 Dec;26(12):3320-5.PMID: 14633821 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of LDL receptor gene mutations and the R3500Q mutation of the apoB gene on lipoprotein phenotype of familial hypercholesterolemic patients from a South European population.

Real JT, Chaves FJ, Ejarque I, García-García AB, Valldecabres C, Ascaso JF, Armengod ME, Carmena R.

Eur J Hum Genet. 2003 Dec;11(12):959-65.PMID: 14508510 [PubMed - indexed for MEDLINE]Related articlesFree article

Additional information on ApoB R3500Q mutation in Spain.

Real JT, Chaves JF, Ascaso JF, Armengod ME, Carmena R.

Atherosclerosis. 2003 Jun;168(2):399-400. No abstract available. PMID: 12801626 [PubMed - indexed for MEDLINE]Related articles

Abdominal obesity, insulin resistance, and metabolic syndrome in a southern European population.

Ascaso JF, Romero P, Real JT, Lorente RI, Marti;nez-Valls J, Carmena R.

Eur J Intern Med. 2003 Mar;14(2):101-106.PMID: 12719027 [PubMed - as supplied by publisher]Related articles

A new case of lipoatrophy with lispro insulin in insulin pump therapy: is there any insulin preparation free of complications?

Ampudia-Blasco FJ, Hasbum B, Carmena R.

Diabetes Care. 2003 Mar;26(3):953-4. No abstract available. PMID: 12610070 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms at the SRBI locus are associated with lipoprotein levels in subjects with heterozygous familial hypercholesterolemia.

Tai ES, Adiconis X, Ordovas JM, Carmena-Ramon R, Real J, Corella D, Ascaso J, Carmena R.

Clin Genet. 2003 Jan;63(1):53-8.PMID: 12519372 [PubMed - indexed for MEDLINE]Related articles

[Influence of plasma lipids, APOE genotype and type of LDL receptor gene mutations on myocardial infarction in subjects with familial hypercholesterolemia]

Real JT, Ascaso JF, Chaves FJ, González C, Puig O, Armengod ME, Carmena R.

Med Clin (Barc). 2002 May 18;118(18):681-5. Spanish. PMID: 12042130 [PubMed - indexed for MEDLINE]Related articles

A proposal to redefine familial combined hyperlipidaemia -- third workshop on FCHL held in Barcelona from 3 to 5 May 2001, during the scientific sessions of the European Society for Clinical Investigation.

Sniderman AD, Castro Cabezas M, Ribalta J, Carmena R, de Bruin TW, de Graaf J, Erkelens DW, Humphries SE, Masana L, Real JT, Talmud PJ, Taskinen MR.

Eur J Clin Invest. 2002 Feb;32(2):71-3. No abstract available. PMID: 11895451 [PubMed - indexed for MEDLINE]Related articles

Impact of obesity in primary hyperlipidemias.

Carmena R, Ascaso JF, Real JT.

Nutr Metab Cardiovasc Dis. 2001 Oct;11(5):354-9. Review.PMID: 11887432 [PubMed - indexed for MEDLINE]Related articles

[Risk factors associated to hospitalization in diabetic patients with foot ulcers]

Real JT, Valls M, Ascaso P, Basanta ML, Viguer A A, Ascaso JF, Carmena R.

Med Clin (Barc). 2001 Nov 24;117(17):641-4. Spanish. PMID: 11734168 [PubMed - indexed for MEDLINE]Related articles

The influence of apo E phenotypes on the plasma triglycerides response to hormonal replacement therapy during the menopause.

Tolosa M, Peiró S, Real JT, Cano A, Ascaso JF, Carmena R.

Maturitas. 2001 Nov 30;40(2):173-81.PMID: 11716996 [PubMed - indexed for MEDLINE]Related articles

[Insulin resistance quantification by fasting insulin plasma values and HOMA index in a non-diabetic population]

Ascaso JF, Romero P, Real JT, Priego A, Valdecabres C, Carmena R.

Med Clin (Barc). 2001 Nov 3;117(14):530-3. Spanish. PMID: 11707218 [PubMed - indexed for MEDLINE]Related articles