PubMed

Peripheral neuropathy in rats exposed to dichloroacetate.

Calcutt NA, Lopez VL, Bautista AD, Mizisin LM, Torres BR, Shroads AL, Mizisin AP, Stacpoole PW.

J Neuropathol Exp Neurol. 2009 Sep;68(9):985-93.PMID: 19680144 [PubMed - indexed for MEDLINE]Related articles

Functional magnetic resonance imaging of the spinal cord during sensory stimulation in diabetic rats.

Malisza KL, Jones C, Gruwel ML, Foreman D, Fernyhough P, Calcutt NA.

J Magn Reson Imaging. 2009 Aug;30(2):271-6.PMID: 19629995 [PubMed - indexed for MEDLINE]Related articles

Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials.

Calcutt NA, Cooper ME, Kern TS, Schmidt AM.

Nat Rev Drug Discov. 2009 May;8(5):417-29. Review.PMID: 19404313 [PubMed - indexed for MEDLINE]Related articles

B vitamins alleviate indices of neuropathic pain in diabetic rats.

Jolivalt CG, Mizisin LM, Nelson A, Cunha JM, Ramos KM, Bonke D, Calcutt NA.

Eur J Pharmacol. 2009 Jun 10;612(1-3):41-7. Epub 2009 Apr 23.PMID: 19393643 [PubMed - indexed for MEDLINE]Related articles

Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growth.

Garcia ML, Rao MV, Fujimoto J, Garcia VB, Shah SB, Crum J, Gotow T, Uchiyama Y, Ellisman M, Calcutt NA, Cleveland DW.

J Neurosci. 2009 Feb 4;29(5):1277-84.PMID: 19193875 [PubMed - indexed for MEDLINE]Related articlesFree article

Allodynia and hyperalgesia in diabetic rats are mediated by GABA and depletion of spinal potassium-chloride co-transporters.

Jolivalt CG, Lee CA, Ramos KM, Calcutt NA.

Pain. 2008 Nov 15;140(1):48-57. Epub 2008 Aug 27.PMID: 18755547 [PubMed - indexed for MEDLINE]Related articlesFree article

Dissociation of thermal hypoalgesia and epidermal denervation in streptozotocin-diabetic mice.

Beiswenger KK, Calcutt NA, Mizisin AP.

Neurosci Lett. 2008 Sep 19;442(3):267-72. Epub 2008 Jul 3.PMID: 18619518 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired prosaposin secretion during nerve regeneration in diabetic rats and protection of nerve regeneration by a prosaposin-derived peptide.

Jolivalt CG, Vu Y, Mizisin LM, Mizisin AP, Calcutt NA.

J Neuropathol Exp Neurol. 2008 Jul;67(7):702-10.PMID: 18596543 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated lipid peroxidation and DNA oxidation in nerve from diabetic rats: effects of aldose reductase inhibition, insulin, and neurotrophic factors.

Cunha JM, Jolivalt CG, Ramos KM, Gregory JA, Calcutt NA, Mizisin AP.

Metabolism. 2008 Jul;57(7):873-81.PMID: 18555826 [PubMed - indexed for MEDLINE]Related articlesFree article

Epidermal nerve fiber quantification in the assessment of diabetic neuropathy.

Beiswenger KK, Calcutt NA, Mizisin AP.

Acta Histochem. 2008;110(5):351-62. Epub 2008 Apr 1. Review.PMID: 18384843 [PubMed - indexed for MEDLINE]Related articlesFree article

The pathological interaction between diabetes and presymptomatic Alzheimer's disease.

Burdo JR, Chen Q, Calcutt NA, Schubert D.

Neurobiol Aging. 2009 Dec;30(12):1910-7. Epub 2008 Mar 26.PMID: 18372080 [PubMed - in process]Related articles

Pathogenesis of pain in peripheral diabetic neuropathy.

Calcutt NA, Backonja MM.

Curr Diab Rep. 2007 Dec;7(6):429-34. Review.PMID: 18255005 [PubMed - indexed for MEDLINE]Related articles

Growth factors as therapeutics for diabetic neuropathy.

Calcutt NA, Jolivalt CG, Fernyhough P.

Curr Drug Targets. 2008 Jan;9(1):47-59. Review.PMID: 18220712 [PubMed - indexed for MEDLINE]Related articles

MALDI-linear ion trap microprobe MS/MS studies of the effects of dichloroacetate on lipid content of nerve tissue.

Landgraf RR, Garrett TJ, Calcutt NA, Stacpoole PW, Yost RA.

Anal Chem. 2007 Nov 1;79(21):8170-5. Epub 2007 Sep 26.PMID: 17894472 [PubMed - indexed for MEDLINE]Related articles

Central action of prosaptide TX14(A) against gp120-induced allodynia in rats.

Jolivalt CG, Dacunha JM, Esch FS, Calcutt NA.

Eur J Pain. 2008 Jan;12(1):76-81. Epub 2007 Apr 26.PMID: 17466547 [PubMed - indexed for MEDLINE]Related articles

Pathogenesis of spinally mediated hyperalgesia in diabetes.

Ramos KM, Jiang Y, Svensson CI, Calcutt NA.

Diabetes. 2007 Jun;56(6):1569-76. Epub 2007 Feb 7.PMID: 17287466 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel sites of aldose reductase immunolocalization in normal and streptozotocin-diabetic rats.

Jiang Y, Calcutt NA, Ramos KM, Mizisin AP.

J Peripher Nerv Syst. 2006 Dec;11(4):274-85. Erratum in: J Peripher Nerv Syst. 2007 Mar;12(1):64. Rames, Khara M [corrected to Ramos, Khara M]. PMID: 17117935 [PubMed - indexed for MEDLINE]Related articles

Dynorphin A, kappa opioid receptors and the antinociceptive efficacy of asimadoline in streptozotocin-induced diabetic rats.

Jolivalt CG, Jiang Y, Freshwater JD, Bartoszyk GD, Calcutt NA.

Diabetologia. 2006 Nov;49(11):2775-85. Epub 2006 Aug 19.PMID: 16924480 [PubMed - indexed for MEDLINE]Related articles

Impaired formalin-evoked changes of spinal amino acid levels in diabetic rats.

Malmberg AB, O'Connor WT, Glennon JC, Ceseña R, Calcutt NA.

Brain Res. 2006 Oct 18;1115(1):48-53. Epub 2006 Aug 22.PMID: 16920081 [PubMed - indexed for MEDLINE]Related articles

Protection of sensory function in diabetic rats by Neotrofin.

Calcutt NA, Freshwater JD, Hauptmann N, Taylor EM, Mizisin AP.

Eur J Pharmacol. 2006 Mar 18;534(1-3):187-93. Epub 2006 Feb 28.PMID: 16507305 [PubMed - indexed for MEDLINE]Related articles

Therapeutic efficacy of prosaposin-derived peptide on different models of allodynia.

Jolivalt CG, Ramos KM, Herbetsson K, Esch FS, Calcutt NA.

Pain. 2006 Mar;121(1-2):14-21. Epub 2006 Feb 9.PMID: 16480831 [PubMed - indexed for MEDLINE]Related articles

Reduced heat sensitivity and epidermal nerve fiber immunostaining following single applications of a high-concentration capsaicin patch.

Malmberg AB, Mizisin AP, Calcutt NA, von Stein T, Robbins WR, Bley KR.

Pain. 2004 Oct;111(3):360-7.PMID: 15363880 [PubMed - indexed for MEDLINE]Related articles

Prevention of sensory disorders in diabetic Sprague-Dawley rats by aldose reductase inhibition or treatment with ciliary neurotrophic factor.

Calcutt NA, Freshwater JD, Mizisin AP.

Diabetologia. 2004 Apr;47(4):718-24.PMID: 15298349 [PubMed - indexed for MEDLINE]Related articles

Ciliary neurotrophic factor improves nerve conduction and ameliorates regeneration deficits in diabetic rats.

Mizisin AP, Vu Y, Shuff M, Calcutt NA.

Diabetes. 2004 Jul;53(7):1807-12.PMID: 15220205 [PubMed - indexed for MEDLINE]Related articlesFree article

Experimental models of painful diabetic neuropathy.

Calcutt NA.

J Neurol Sci. 2004 May 15;220(1-2):137-9. No abstract available. PMID: 15140623 [PubMed - indexed for MEDLINE]Related articles

Modeling diabetic sensory neuropathy in rats.

Calcutt NA.

Methods Mol Med. 2004;99:55-65.PMID: 15131329 [PubMed - indexed for MEDLINE]Related articles

NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth.

Garcia ML, Lobsiger CS, Shah SB, Deerinck TJ, Crum J, Young D, Ward CM, Crawford TO, Gotow T, Uchiyama Y, Ellisman MH, Calcutt NA, Cleveland DW.

J Cell Biol. 2003 Dec 8;163(5):1011-20.PMID: 14662745 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing.

Svensson CI, Marsala M, Westerlund A, Calcutt NA, Campana WM, Freshwater JD, Catalano R, Feng Y, Protter AA, Scott B, Yaksh TL.

J Neurochem. 2003 Sep;86(6):1534-44.PMID: 12950462 [PubMed - indexed for MEDLINE]Related articles

Neurotrophin-3 prevents the proximal accumulation of neurofilament proteins in sensory neurons of streptozocin-induced diabetic rats.

Sayers NM, Beswick LJ, Middlemas A, Calcutt NA, Mizisin AP, Tomlinson DR, Fernyhough P.

Diabetes. 2003 Sep;52(9):2372-80.PMID: 12941778 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia.

Huang TJ, Price SA, Chilton L, Calcutt NA, Tomlinson DR, Verkhratsky A, Fernyhough P.

Diabetes. 2003 Aug;52(8):2129-36.PMID: 12882932 [PubMed - indexed for MEDLINE]Related articlesFree article

Future treatments for diabetic neuropathy: clues from experimental neuropathy.

Calcutt NA.

Curr Diab Rep. 2002 Dec;2(6):482-8. Review.PMID: 12643154 [PubMed - indexed for MEDLINE]Related articles

Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy.

Calcutt NA, Allendoerfer KL, Mizisin AP, Middlemas A, Freshwater JD, Burgers M, Ranciato R, Delcroix JD, Taylor FR, Shapiro R, Strauch K, Dudek H, Engber TM, Galdes A, Rubin LL, Tomlinson DR.

J Clin Invest. 2003 Feb;111(4):507-14.PMID: 12588889 [PubMed - indexed for MEDLINE]Related articlesFree article

Injury type-specific calcium channel alpha 2 delta-1 subunit up-regulation in rat neuropathic pain models correlates with antiallodynic effects of gabapentin.

Luo ZD, Calcutt NA, Higuera ES, Valder CR, Song YH, Svensson CI, Myers RR.

J Pharmacol Exp Ther. 2002 Dec;303(3):1199-205.PMID: 12438544 [PubMed - indexed for MEDLINE]Related articlesFree article

Potential mechanisms of neuropathic pain in diabetes.

Calcutt NA.

Int Rev Neurobiol. 2002;50:205-28. Review.PMID: 12198811 [PubMed - indexed for MEDLINE]Related articles

Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport.

Rao MV, Garcia ML, Miyazaki Y, Gotow T, Yuan A, Mattina S, Ward CM, Calcutt NA, Uchiyama Y, Nixon RA, Cleveland DW.

J Cell Biol. 2002 Aug 19;158(4):681-93. Epub 2002 Aug 19.PMID: 12186852 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats.

Freshwater JD, Svensson CI, Malmberg AB, Calcutt NA.

Diabetes. 2002 Jul;51(7):2249-55.PMID: 12086957 [PubMed - indexed for MEDLINE]Related articlesFree article

TX14(A), a prosaposin-derived peptide, reverses established nerve disorders in streptozotocin-diabetic rats and prevents them in galactose-fed rats.

Mizisin AP, Steinhardt RC, O'Brien JS, Calcutt NA.

J Neuropathol Exp Neurol. 2001 Oct;60(10):953-60.PMID: 11589426 [PubMed - indexed for MEDLINE]Related articles

Prosaposin-derived peptides enhanced sprouting of sensory neurons in vitro and induced sprouting at motor endplates in vivo.

Campana WM, Mohiuddin L, Misasi R, O'Brien JS, Calcutt NA.

J Peripher Nerv Syst. 2000 Sep;5(3):126-30.PMID: 11442168 [PubMed - indexed for MEDLINE]Related articles

Prosaposin is immunolocalized to muscle and prosaptides promote myoblast fusion and attenuate loss of muscle mass after nerve injury.

Rende M, Brizi E, Donato R, Provenzano C, Bruno R, Mizisin AP, Garrett RS, Calcutt NA, Campana WM, O'Brien JS.

Muscle Nerve. 2001 Jun;24(6):799-808.PMID: 11360264 [PubMed - indexed for MEDLINE]Related articles

Protection of sensory function and antihyperalgesic properties of a prosaposin-derived peptide in diabetic rats.

Calcutt NA, Freshwater JD, O'Brien JS.

Anesthesiology. 2000 Nov;93(5):1271-8.PMID: 11046216 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated substance-P-like immunoreactivity levels in spinal dialysates during the formalin test in normal and diabetic rats.

Calcutt NA, Stiller C, Gustafsson H, Malmberg AB.

Brain Res. 2000 Feb 21;856(1-2):20-7.PMID: 10677607 [PubMed - indexed for MEDLINE]Related articles

Neurotrophin-3 reverses nerve conduction velocity deficits in streptozotocin-diabetic rats.

Mizisin AP, Calcutt NA, Tomlinson DR, Gallagher A, Fernyhough P.

J Peripher Nerv Syst. 1999;4(3-4):211-21.PMID: 10642089 [PubMed - indexed for MEDLINE]Related articles

Neuronal nitric oxide synthase mRNA upregulation in rat sensory neurons after spinal nerve ligation: lack of a role in allodynia development.

Luo ZD, Chaplan SR, Scott BP, Cizkova D, Calcutt NA, Yaksh TL.

J Neurosci. 1999 Nov 1;19(21):9201-8.PMID: 10531423 [PubMed - indexed for MEDLINE]Related articlesFree article

Prosaposin gene expression and the efficacy of a prosaposin-derived peptide in preventing structural and functional disorders of peripheral nerve in diabetic rats.

Calcutt NA, Campana WM, Eskeland NL, Mohiuddin L, Dines KC, Mizisin AP, O'Brien JS.

J Neuropathol Exp Neurol. 1999 Jun;58(6):628-36.PMID: 10374753 [PubMed - indexed for MEDLINE]Related articles

Effects of hindlimb temperature on sciatic nerve laser Doppler vascular conductance in control and streptozotocin-diabetic rats.

Dines KC, Calcutt NA, Nunag KD, Mizisin AP, Kalichman MW.

J Neurol Sci. 1999 Feb 1;163(1):17-24.PMID: 10223405 [PubMed - indexed for MEDLINE]Related articles

Effects of diabetes on tissue content and evoked release of calcitonin gene-related peptide-like immunoreactivity from rat sensory nerves.

Calcutt NA, Chen P, Hua XY.

Neurosci Lett. 1998 Oct 2;254(3):129-32.PMID: 10214974 [PubMed - indexed for MEDLINE]Related articles

Gabapentin prevents hyperalgesia during the formalin test in diabetic rats.

Ceseña RM, Calcutt NA.

Neurosci Lett. 1999 Mar 5;262(2):101-4.PMID: 10203241 [PubMed - indexed for MEDLINE]Related articles

Necrotizing myopathy induced by overexpression of interferon-gamma in transgenic mice.

Shelton GD, Calcutt NA, Garrett RS, Gu D, Sarvetnick N, Campana WM, Powell HC.

Muscle Nerve. 1999 Feb;22(2):156-65.PMID: 10024128 [PubMed - indexed for MEDLINE]Related articles

Effects of the peptide HP228 on nerve disorders in diabetic rats.

Calcutt NA, Dines KC, Ceseña RM.

Metabolism. 1998 Jun;47(6):650-6.PMID: 9627361 [PubMed - indexed for MEDLINE]Related articles

Effects of sorbitol dehydrogenase deficiency on nerve conduction in experimental diabetic mice.

Ng TF, Lee FK, Song ZT, Calcutt NA, Lee AY, Chung SS, Chung SK.

Diabetes. 1998 Jun;47(6):961-6. Erratum in: Diabetes 1998 Aug;47(8):1374. Ng, DT [corrected to Ng, TF]; Lee, LW [corrected to Lee, AY]. PMID: 9604875 [PubMed - indexed for MEDLINE]Related articlesFree article