PubMed

Pharmacokinetics of rizatriptan tablets during and between migraine attacks.

Cutler NR, Jhee SS, Majumdar AK, McLaughlin D, Brucker MJ, Carides AD, Kramer MS, Matzura-Wolfe D, Reines SA, Goldberg MR.

Headache. 1999 Apr;39(4):264-9.PMID: 15613223 [PubMed - indexed for MEDLINE]Related articles

A randomized evaluation of the effects of six antipsychotic agents on QTc, in the absence and presence of metabolic inhibition.

Harrigan EP, Miceli JJ, Anziano R, Watsky E, Reeves KR, Cutler NR, Sramek J, Shiovitz T, Middle M.

J Clin Psychopharmacol. 2004 Feb;24(1):62-9.PMID: 14709949 [PubMed - indexed for MEDLINE]Related articles

The effect of antipsychotics on plasma lipids.

Sramek JJ, Cutler NR, Shiovitz T.

J Clin Psychopharmacol. 2003 Dec;23(6):679-80. No abstract available. PMID: 14624207 [PubMed - indexed for MEDLINE]Related articles

Galantamine hydrobromide: an agent for Alzheimer's disease.

Zarotsky V, Sramek JJ, Cutler NR.

Am J Health Syst Pharm. 2003 Mar 1;60(5):446-52. Review.PMID: 12635450 [PubMed - indexed for MEDLINE]Related articles

Inhibition of acetyl- and butyryl-cholinesterase in the cerebrospinal fluid of patients with Alzheimer's disease by rivastigmine: correlation with cognitive benefit.

Giacobini E, Spiegel R, Enz A, Veroff AE, Cutler NR.

J Neural Transm. 2002 Jul;109(7-8):1053-65.PMID: 12111443 [PubMed - indexed for MEDLINE]Related articles

Generalised anxiety disorder: treatment options.

Sramek JJ, Zarotsky V, Cutler NR.

Drugs. 2002;62(11):1635-48. Review.PMID: 12109925 [PubMed - indexed for MEDLINE]Related articles

Centrally acting antiemetics mitigate nausea and vomiting in patients with Alzheimer's disease who receive rivastigmine.

Jhee SS, Shiovitz T, Hartman RD, Messina J, Anand R, Sramek J, Cutler NR.

Clin Neuropharmacol. 2002 Mar-Apr;25(2):122-3. No abstract available. PMID: 11981242 [PubMed - indexed for MEDLINE]Related articles

Estimation of the absolute bioavailability of rivastigmine in patients with mild to moderate dementia of the Alzheimer's type.

Hossain M, Jhee SS, Shiovitz T, McDonald C, Sedek G, Pommier F, Cutler NR.

Clin Pharmacokinet. 2002;41(3):225-34.PMID: 11929322 [PubMed - indexed for MEDLINE]Related articles

Brasofensine treatment for Parkinson's disease in combination with levodopa/carbidopa.

Frackiewicz EJ, Jhee SS, Shiovitz TM, Webster J, Topham C, Dockens RC, Whigan D, Salazar DE, Cutler NR.

Ann Pharmacother. 2002 Feb;36(2):225-30.PMID: 11847938 [PubMed - indexed for MEDLINE]Related articles

Efficacy and safety of sibutramine for weight loss in obese patients with hypertension well controlled by beta-adrenergic blocking agents: a placebo-controlled, double-blind, randomised trial.

Sramek JJ, Leibowitz MT, Weinstein SP, Rowe ED, Mendel CM, Levy B, McMahon FG, Mullican WS, Toth PD, Cutler NR.

J Hum Hypertens. 2002 Jan;16(1):13-9.PMID: 11840225 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacokinetics and tolerability of buspirone during oral administration to children and adolescents with anxiety disorder and normal healthy adults.

Salazar DE, Frackiewicz EJ, Dockens R, Kollia G, Fulmor IE, Tigel PD, Uderman HD, Shiovitz TM, Sramek JJ, Cutler NR.

J Clin Pharmacol. 2001 Dec;41(12):1351-8.PMID: 11762563 [PubMed - indexed for MEDLINE]Related articles

Safety and efficacy of PNU-142633, a selective 5-HT1D agonist, in patients with acute migraine.

Gomez-Mancilla B, Cutler NR, Leibowitz MT, Spierings EL, Klapper JA, Diamond S, Goldstein J, Smith T, Couch JR, Fleishaker J, Azie N, Blunt DE.

Cephalalgia. 2001 Sep;21(7):727-32.PMID: 11595000 [PubMed - indexed for MEDLINE]Related articles

Pharmacokinetic-pharmacodynamic modeling of rivastigmine, a cholinesterase inhibitor, in patients with Alzheimer's disease.

Gobburu JV, Tammara V, Lesko L, Jhee SS, Sramek JJ, Cutler NR, Yuan R.

J Clin Pharmacol. 2001 Oct;41(10):1082-90.PMID: 11583476 [PubMed - indexed for MEDLINE]Related articles

Pharmacokinetics and pharmacodynamics of the triptan antimigraine agents: a comparative review.

Jhee SS, Shiovitz T, Crawford AW, Cutler NR.

Clin Pharmacokinet. 2001;40(3):189-205. Review.PMID: 11327198 [PubMed - indexed for MEDLINE]Related articles

Pharmacokinetic studies of antipsychotics in healthy volunteers versus patients.

Cutler NR.

J Clin Psychiatry. 2001;62 Suppl 5:10-3; discussion 23-4.PMID: 11305842 [PubMed - indexed for MEDLINE]Related articles

The status of ongoing trials for mild cognitive impairment.

Sramek JJ, Veroff AE, Cutler NR.

Expert Opin Investig Drugs. 2001 Apr;10(4):741-52. Review.PMID: 11281823 [PubMed - indexed for MEDLINE]Related articles

Beta-amyloid therapies in Alzheimer's disease.

Jhee S, Shiovitz T, Crawford AW, Cutler NR.

Expert Opin Investig Drugs. 2001 Apr;10(4):593-605. Review.PMID: 11281811 [PubMed - indexed for MEDLINE]Related articles

Review of the next generation of Alzheimer's disease therapeutics: challenges for drug development.

Cutler NR, Sramek JJ.

Prog Neuropsychopharmacol Biol Psychiatry. 2001 Jan;25(1):27-57. Review.PMID: 11263756 [PubMed - indexed for MEDLINE]Related articles

RBC cholinesterase inhibition: a useful surrogate marker for cholinesterase inhibitor activity in Alzheimer disease therapy?

Sramek JJ, Cutler NR.

Alzheimer Dis Assoc Disord. 2000 Oct-Dec;14(4):216-27. Review.PMID: 11186600 [PubMed - indexed for MEDLINE]Related articles

Women's health care during the perimenopause.

Frackiewicz EJ, Cutler NR.

J Am Pharm Assoc (Wash). 2000 Nov-Dec;40(6):800-11. Review.PMID: 11111360 [PubMed - indexed for MEDLINE]Related articles

Investigator perspective on MTD: practical application of an MTD definition--has it accelerated development?

Cutler NR, Sramek JJ.

J Clin Pharmacol. 2000 Nov;40(11):1184-7; discussion 1202-4. No abstract available. PMID: 11075302 [PubMed - indexed for MEDLINE]Related articles

Review of the acetylcholinesterase inhibitor galanthamine.

Sramek JJ, Frackiewicz EJ, Cutler NR.

Expert Opin Investig Drugs. 2000 Oct;9(10):2393-402. Review.PMID: 11060814 [PubMed - indexed for MEDLINE]Related articles

Ongoing trials in Alzheimer's disease.

Sramek JJ, Cutler NR.

Expert Opin Investig Drugs. 2000 Apr;9(4):899-915. Review.PMID: 11060718 [PubMed - indexed for MEDLINE]Related articles

Mild cognitive impairment: emerging therapeutics.

Sramek JJ, Veroff AE, Cutler NR.

Ann Pharmacother. 2000 Oct;34(10):1179-88. Review.PMID: 11054988 [PubMed - indexed for MEDLINE]Related articles

Gender differences in depression and antidepressant pharmacokinetics and adverse events.

Frackiewicz EJ, Sramek JJ, Cutler NR.

Ann Pharmacother. 2000 Jan;34(1):80-8. Review.PMID: 10669189 [PubMed - indexed for MEDLINE]Related articles

A bridging study of fananserin in schizophrenic patients.

Sramek JJ, Kirkesseli S, Paccaly-Moulin A, Davidson J, Jhee SS, Hourani J, Sémiond D, Cutler NR.

Psychopharmacol Bull. 1998;34(4):811-8.PMID: 10513457 [PubMed - indexed for MEDLINE]Related articles

Recent developments in the drug treatment of Alzheimer's disease.

Sramek JJ, Cutler NR.

Drugs Aging. 1999 May;14(5):359-73. Review.PMID: 10408736 [PubMed - indexed for MEDLINE]Related articles

Meta-analysis of the safety and tolerability of two dose regimens of buspirone in patients with persistent anxiety.

Sramek JJ, Hong WW, Hamid S, Nape B, Cutler NR.

Depress Anxiety. 1999;9(3):131-4.PMID: 10356651 [PubMed - indexed for MEDLINE]Related articles

Cholinesterase inhibitors: a therapeutic strategy for Alzheimer disease.

Krall WJ, Sramek JJ, Cutler NR.

Ann Pharmacother. 1999 Apr;33(4):441-50. Review.PMID: 10332536 [PubMed - indexed for MEDLINE]Related articles

A double-blind, randomized, crossover assessment of blood pressure following administration of avitriptan, sumatriptan, or placebo to patients with mild to moderate hypertension.

Jhee SS, Salazar DE, Ford NF, Fulmor IE, Sramek JJ, Cutler NR.

Cephalalgia. 1999 Mar;19(2):95-9.PMID: 10214534 [PubMed - indexed for MEDLINE]Related articles

NXX-066 in patients with Alzheimer's disease: a bridging study.

Sramek JJ, Hourani J, Jhee SS, Cutler NR.

Life Sci. 1999;64(14):1215-21.PMID: 10210264 [PubMed - indexed for MEDLINE]Related articles

Efficacy of xanomeline in Alzheimer disease: cognitive improvement measured using the Computerized Neuropsychological Test Battery (CNTB).

Veroff AE, Bodick NC, Offen WW, Sramek JJ, Cutler NR.

Alzheimer Dis Assoc Disord. 1998 Dec;12(4):304-12.PMID: 9876958 [PubMed - indexed for MEDLINE]Related articles

Sertraline in children and adolescents with obsessive-compulsive disorder: a multicenter randomized controlled trial.

March JS, Biederman J, Wolkow R, Safferman A, Mardekian J, Cook EH, Cutler NR, Dominguez R, Ferguson J, Muller B, Riesenberg R, Rosenthal M, Sallee FR, Wagner KD, Steiner H.

JAMA. 1998 Nov 25;280(20):1752-6. Erratum in: JAMA 2000 Mar 8;283(10):1293. PMID: 9842950 [PubMed - indexed for MEDLINE]Related articlesFree article

Exploratory studies: implications for drug development in Alzheimer's disease.

Cutler NR, Sramek JJ.

Rev Neurol (Paris). 1998;154 Suppl 2:S131-6. Review.PMID: 9834554 [PubMed - indexed for MEDLINE]Related articles

Pharmacokinetics and pharmacodynamics of avitriptan in patients with migraine after oral dosing.

Cutler NR, Salazar DE, Jhee SS, Fulmor IE, Ford N, Smith RA, Sramek JJ.

Headache. 1998 Jun;38(6):446-52.PMID: 9664749 [PubMed - indexed for MEDLINE]Related articles

Long-term efficacy, tolerability, and safety of the combination of enalapril and felodipine ER in the treatment of hypertension. Enalapril-Felodipine ER Factorial Study Group.

Gradman AH, Cutler NR, Davis PJ, Robbins JA, Weiss RJ, Wood BC, Michelson EL.

Clin Ther. 1998 May-Jun;20(3):527-38.PMID: 9663368 [PubMed - indexed for MEDLINE]Related articles

Guidelines for conducting bridging studies in Alzheimer disease.

Cutler NR, Sramek JJ.

Alzheimer Dis Assoc Disord. 1998 Jun;12(2):88-92.PMID: 9651137 [PubMed - indexed for MEDLINE]Related articles

Safety and tolerability of metrifonate in patients with Alzheimer's disease: results of a maximum tolerated dose study.

Cutler NR, Jhee SS, Cyrus P, Bieber F, TanPiengco P, Sramek JJ, Gulanski B.

Life Sci. 1998;62(16):1433-41.PMID: 9585171 [PubMed - indexed for MEDLINE]Related articles

Dose-dependent CSF acetylcholinesterase inhibition by SDZ ENA 713 in Alzheimer's disease.

Cutler NR, Polinsky RJ, Sramek JJ, Enz A, Jhee SS, Mancione L, Hourani J, Zolnouni P.

Acta Neurol Scand. 1998 Apr;97(4):244-50.PMID: 9576639 [PubMed - indexed for MEDLINE]Related articles

Initial safety, tolerability pharmacodynamics, and pharmacokinetics of CI-1007 in patients with schizophrenia.

Sramek JJ, Eldon MA, Posvar E, Feng MR, Jhee SS, Hourani J, Sedman AJ, Cutler NR.

Psychopharmacol Bull. 1998;34(1):93-9.PMID: 9564205 [PubMed - indexed for MEDLINE]Related articles

Defining the maximum tolerated dose: investigator, academic, industry and regulatory perspectives.

Cutler NR, Sramek JJ, Greenblatt DJ, Chaikin P, Ford N, Lesko LJ, Davis B, Williams RL.

J Clin Pharmacol. 1997 Sep;37(9):767-83. No abstract available. PMID: 9549630 [PubMed - indexed for MEDLINE]Related articles

Monitoring of acute migraine attacks: placebo response and safety data.

Jhee SS, Salazar DE, Ford NF, Fulmor IE, Sramek JJ, Cutler NR.

Headache. 1998 Jan;38(1):35-8.PMID: 9505001 [PubMed - indexed for MEDLINE]Related articles

A bridging study of LU 25-109 in patients with probable Alzheimer's disease.

Sramek JJ, Forrest M, Mengel H, Jhee SS, Hourani J, Cutler NR.

Life Sci. 1998;62(3):195-202.PMID: 9488097 [PubMed - indexed for MEDLINE]Related articles

Potential for adverse events in patients with generalized anxiety disorder.

Frackiewicz-Koziol EJ, Sramek JJ, Cutler NR.

Ann Pharmacother. 1998 Jan;32(1):132-4. Review. No abstract available. PMID: 9475839 [PubMed - indexed for MEDLINE]Related articles

Ethnicity and antipsychotic response.

Frackiewicz EJ, Sramek JJ, Herrera JM, Kurtz NM, Cutler NR.

Ann Pharmacother. 1997 Nov;31(11):1360-9. Review.PMID: 9391692 [PubMed - indexed for MEDLINE]Related articles

Two rapid-dose titrations of sertindole in patients with schizophrenia.

Sramek JJ, Mack RJ, Awni W, Hourani J, Jhee SS, Barto S, Cutler NR.

J Clin Psychopharmacol. 1997 Oct;17(5):419-22.PMID: 9315993 [PubMed - indexed for MEDLINE]Related articles

Penetration of trovafloxacin into cerebrospinal fluid in humans following intravenous infusion of alatrofloxacin.

Cutler NR, Vincent J, Jhee SS, Teng R, Wardle T, Lucas G, Dogolo LC, Sramek JJ.

Antimicrob Agents Chemother. 1997 Jun;41(6):1298-300.PMID: 9174187 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and safety of two dosing regimens of buspirone in the treatment of outpatients with persistent anxiety.

Sramek JJ, Frackiewicz EJ, Cutler NR.

Clin Ther. 1997 May-Jun;19(3):498-506.PMID: 9220214 [PubMed - indexed for MEDLINE]Related articles

Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease.

Bodick NC, Offen WW, Levey AI, Cutler NR, Gauthier SG, Satlin A, Shannon HE, Tollefson GD, Rasmussen K, Bymaster FP, Hurley DJ, Potter WZ, Paul SM.

Arch Neurol. 1997 Apr;54(4):465-73.PMID: 9109749 [PubMed - indexed for MEDLINE]Related articles

Combined enalapril and felodipine extended release (ER) for systemic hypertension. Enalapril-Felodipine ER Factorial Study Group.

Gradman AH, Cutler NR, Davis PJ, Robbins JA, Weiss RJ, Wood BC.

Am J Cardiol. 1997 Feb 15;79(4):431-5.PMID: 9052345 [PubMed - indexed for MEDLINE]Related articles