PubMed

In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1.

Ahamed J, Janczak CA, Wittkowski KM, Coller BS.

PLoS One. 2009 Aug 12;4(8):e6608.PMID: 19672301 [PubMed - in process]Related articlesFree article

Targeted molecular dynamics reveals overall common conformational changes upon hybrid domain swing-out in beta3 integrins.

Provasi D, Murcia M, Coller BS, Filizola M.

Proteins. 2009 Nov 1;77(2):477-89.PMID: 19455709 [PubMed - indexed for MEDLINE]Related articlesFree article

Translational careers.

Andrews N, Burris JE, Cech TR, Coller BS, Crowley WF Jr, Gallin EK, Kelner KL, Kirch DG, Leshner AI, Morris CD, Nguyen FT, Oates J, Sung NS.

Science. 2009 May 15;324(5929):855. No abstract available. PMID: 19443750 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel alphaIIb-specific alphaIIbbeta3 antagonist.

Blue R, Kowalska MA, Hirsch J, Murcia M, Janczak CA, Harrington A, Jirouskova M, Li J, Fuentes R, Thornton MA, Filizola M, Poncz M, Coller BS.

Blood. 2009 Jul 2;114(1):195-201. Epub 2009 May 4.PMID: 19414864 [PubMed - indexed for MEDLINE]Related articles

The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend.

Coller BS, Shattil SJ.

Blood. 2008 Oct 15;112(8):3011-25. Review.PMID: 18840725 [PubMed - indexed for MEDLINE]Related articlesFree article

Translational research: forging a new cultural identity.

Coller BS.

Mt Sinai J Med. 2008 Oct;75(5):478-87. No abstract available. PMID: 18828172 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-beta1.

Ahamed J, Burg N, Yoshinaga K, Janczak CA, Rifkin DB, Coller BS.

Blood. 2008 Nov 1;112(9):3650-60. Epub 2008 Jun 10.PMID: 18544680 [PubMed - indexed for MEDLINE]Related articlesFree article

Morphological and functional platelet abnormalities in Berkeley sickle cell mice.

Shet AS, Hoffmann TJ, Jirouskova M, Janczak CA, Stevens JR, Adamson A, Mohandas N, Manci EA, Cynober T, Coller BS.

Blood Cells Mol Dis. 2008 Jul-Aug;41(1):109-18. Epub 2008 Apr 18.PMID: 18374611 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional and computational studies of the ligand-associated metal binding site of beta3 integrins.

Murcia M, Jirouskova M, Li J, Coller BS, Filizola M.

Proteins. 2008 Jun;71(4):1779-91.PMID: 18175315 [PubMed - indexed for MEDLINE]Related articlesFree article

Disulfide bond disruption by a beta 3-Cys549Arg mutation in six Jordanian families with Glanzmann thrombasthenia causes diminished production of constitutively active alpha IIb beta 3.

Mor-Cohen R, Rosenberg N, Peretz H, Landau M, Coller BS, Awidi A, Seligsohn U.

Thromb Haemost. 2007 Dec;98(6):1257-65.PMID: 18064323 [PubMed - indexed for MEDLINE]Related articles

Application of high-throughput screening to identify a novel alphaIIb-specific small- molecule inhibitor of alphaIIbbeta3-mediated platelet interaction with fibrinogen.

Blue R, Murcia M, Karan C, Jirousková M, Coller BS.

Blood. 2008 Feb 1;111(3):1248-56. Epub 2007 Oct 31.PMID: 17978171 [PubMed - indexed for MEDLINE]Related articlesFree article

Ligand density dramatically affects integrin alpha IIb beta 3-mediated platelet signaling and spreading.

Jirousková M, Jaiswal JK, Coller BS.

Blood. 2007 Jun 15;109(12):5260-9. Epub 2007 Mar 1.PMID: 17332246 [PubMed - indexed for MEDLINE]Related articlesFree article

Mapping early conformational changes in alphaIIb and beta3 during biogenesis reveals a potential mechanism for alphaIIbbeta3 adopting its bent conformation.

Mitchell WB, Li J, Murcia M, Valentin N, Newman PJ, Coller BS.

Blood. 2007 May 1;109(9):3725-32. Epub 2007 Jan 5.PMID: 17209052 [PubMed - indexed for MEDLINE]Related articlesFree article

The physician-scientist, the state, and the oath: thoughts for our times.

Coller BS.

J Clin Invest. 2006 Oct;116(10):2567-70.PMID: 17016549 [PubMed - indexed for MEDLINE]Related articlesFree article

Diversity of Glanzmann thrombasthenia in southern India: 10 novel mutations identified among 15 unrelated patients.

Nelson EJ, Nair SC, Peretz H, Coller BS, Seligsohn U, Chandy M, Srivastava A.

J Thromb Haemost. 2006 Aug;4(8):1730-7.PMID: 16879215 [PubMed - indexed for MEDLINE]Related articles

Molecular diversity of Glanzmann thrombasthenia in southern India: new insights into mRNA splicing and structure-function correlations of alphaIIbbeta3 integrin (ITGA2B, ITGB3).

Peretz H, Rosenberg N, Landau M, Usher S, Nelson EJ, Mor-Cohen R, French DL, Mitchell BW, Nair SC, Chandy M, Coller BS, Srivastava A, Seligsohn U.

Hum Mutat. 2006 Apr;27(4):359-69.PMID: 16463284 [PubMed - indexed for MEDLINE]Related articles

Three novel beta-propeller mutations causing Glanzmann thrombasthenia result in production of normally stable pro-alphaIIb, but variably impaired progression of pro-alphaIIbbeta3 from endoplasmic reticulum to Golgi.

Nelson EJ, Li J, Mitchell WB, Chandy M, Srivastava A, Coller BS.

J Thromb Haemost. 2005 Dec;3(12):2773-83.PMID: 16359515 [PubMed - indexed for MEDLINE]Related articlesFree article

A 13-bp deletion in alpha(IIb) gene is a founder mutation that predominates in Palestinian-Arab patients with Glanzmann thrombasthenia.

Rosenberg N, Hauschner H, Peretz H, Mor-Cohen R, Landau M, Shenkman B, Kenet G, Coller BS, Awidi AA, Seligsohn U.

J Thromb Haemost. 2005 Dec;3(12):2764-72.PMID: 16359514 [PubMed - indexed for MEDLINE]Related articlesFree article

alphaIIbbeta3 biogenesis is controlled by engagement of alphaIIb in the calnexin cycle via the N15-linked glycan.

Mitchell WB, Li J, French DL, Coller BS.

Blood. 2006 Apr 1;107(7):2713-9. Epub 2005 Nov 22.PMID: 16304048 [PubMed - indexed for MEDLINE]Related articlesFree article

Pathology of Berkeley sickle cell mice: similarities and differences with human sickle cell disease.

Manci EA, Hillery CA, Bodian CA, Zhang ZG, Lutty GA, Coller BS.

Blood. 2006 Feb 15;107(4):1651-8. Epub 2005 Sep 15.PMID: 16166585 [PubMed - indexed for MEDLINE]Related articlesFree article

Fibrin but not adsorbed fibrinogen supports fibronectin assembly by spread platelets. Effects of the interaction of alphaIIb beta3 with the C terminus of the fibrinogen gamma-chain.

Cho J, Degen JL, Coller BS, Mosher DF.

J Biol Chem. 2005 Oct 21;280(42):35490-8. Epub 2005 Jul 28.PMID: 16051597 [PubMed - indexed for MEDLINE]Related articlesFree article

Leukocytosis and ischemic vascular disease morbidity and mortality: is it time to intervene?

Coller BS.

Arterioscler Thromb Vasc Biol. 2005 Apr;25(4):658-70. Epub 2005 Jan 20. Review.PMID: 15662026 [PubMed - indexed for MEDLINE]Related articlesFree article

Monocyte-derived tissue factor contributes to stent thrombosis in an in vitro system.

Palmerini T, Coller BS, Cervi V, Tomasi L, Marzocchi A, Marrozzini C, Leone O, Piccioli M, Branzi A.

J Am Coll Cardiol. 2004 Oct 19;44(8):1570-7.PMID: 15489087 [PubMed - indexed for MEDLINE]Related articles

Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics.

Xiao T, Takagi J, Coller BS, Wang JH, Springer TA.

Nature. 2004 Nov 4;432(7013):59-67. Epub 2004 Sep 19.PMID: 15378069 [PubMed - indexed for MEDLINE]Related articles

Evidence for megakaryocyte engraftment following reduced-intensity conditioning.

French DL, Fruchtman S, Mitchell WB, Coller BS, Peretz H.

Exp Hematol. 2004 Sep;32(9):877-80.PMID: 15345290 [PubMed - indexed for MEDLINE]Related articles

Integrin beta3 regions controlling binding of murine mAb 7E3: implications for the mechanism of integrin alphaIIbbeta3 activation.

Artoni A, Li J, Mitchell B, Ruan J, Takagi J, Springer TA, French DL, Coller BS.

Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13114-20. Epub 2004 Jul 26.PMID: 15277669 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanistic insights from a refined three-dimensional model of integrin alphaIIbbeta3.

Filizola M, Hassan SA, Artoni A, Coller BS, Weinstein H.

J Biol Chem. 2004 Jun 4;279(23):24624-30. Epub 2004 Mar 30.PMID: 15056669 [PubMed - indexed for MEDLINE]Related articlesFree article

Reflections on being a Chair of Medicine, 1993 to 2001 - Part 2.

Coller BS.

Am J Med. 2004 Jan 15;116(2):141-4. No abstract available. PMID: 14715334 [PubMed - indexed for MEDLINE]Related articles

Reflections on being a chair of medicine, 1993 to 2001--part 1.

Coller BS.

Am J Med. 2004 Jan 1;116(1):68-72. No abstract available. PMID: 14706675 [PubMed - indexed for MEDLINE]Related articles

A monoclonal antibody to the fibrinogen gamma-chain alters fibrin clot structure and its properties by producing short, thin fibers arranged in bundles.

Scheiner T, Jirousková M, Nagaswami C, Coller BS, Weisel JW.

J Thromb Haemost. 2003 Dec;1(12):2594-602.PMID: 14675095 [PubMed - indexed for MEDLINE]Related articles

Antibody blockade or mutation of the fibrinogen gamma-chain C-terminus is more effective in inhibiting murine arterial thrombus formation than complete absence of fibrinogen.

Jirousková M, Chereshnev I, Väänänen H, Degen JL, Coller BS.

Blood. 2004 Mar 15;103(6):1995-2002. Epub 2003 Nov 26.PMID: 14644995 [PubMed - indexed for MEDLINE]Related articlesFree article

Intravenous immune globulin prevents venular vaso-occlusion in sickle cell mice by inhibiting leukocyte adhesion and the interactions between sickle erythrocytes and adherent leukocytes.

Turhan A, Jenab P, Bruhns P, Ravetch JV, Coller BS, Frenette PS.

Blood. 2004 Mar 15;103(6):2397-400. Epub 2003 Nov 20.PMID: 14630831 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of angiogenesis and tumor growth by murine 7E3, the parent antibody of c7E3 Fab (abciximab; ReoPro).

Varner JA, Nakada MT, Jordan RE, Coller BS.

Angiogenesis. 1999;3(1):53-60.PMID: 14517444 [PubMed]Related articles

Role of P-selectin, beta2-integrins, and Src tyrosine kinases in mouse neutrophil-platelet adhesion.

Evangelista V, Manarini S, Coller BS, Smyth SS.

J Thromb Haemost. 2003 May;1(5):1048-54.PMID: 12871376 [PubMed - indexed for MEDLINE]Related articles

Adjuvant treatment with a glycoprotein IIb/IIIa receptor inhibitor increases the therapeutic window for low-dose tissue plasminogen activator administration in a rat model of embolic stroke.

Zhang L, Zhang ZG, Zhang R, Morris D, Lu M, Coller BS, Chopp M.

Circulation. 2003 Jun 10;107(22):2837-43. Epub 2003 May 19.PMID: 12756151 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynamics of GPIIb/IIIa-mediated platelet-platelet interactions in platelet adhesion/thrombus formation on collagen in vitro as revealed by videomicroscopy.

Patel D, Väänänen H, Jirousková M, Hoffmann T, Bodian C, Coller BS.

Blood. 2003 Feb 1;101(3):929-36.PMID: 12529292 [PubMed - indexed for MEDLINE]Related articlesFree article

Two novel mutations in the alpha IIb calcium-binding domains identify hydrophobic regions essential for alpha IIbbeta 3 biogenesis.

Mitchell WB, Li JH, Singh F, Michelson AD, Bussel J, Coller BS, French DL.

Blood. 2003 Mar 15;101(6):2268-76. Epub 2002 Nov 7.PMID: 12424194 [PubMed - indexed for MEDLINE]Related articlesFree article

Science and humanism: the twin pillars of medicine.

Coller BS.

Mt Sinai J Med. 2002 Oct;69(5):277-9. No abstract available. PMID: 12415320 [PubMed - indexed for MEDLINE]Related articlesFree article

Two new beta3 integrin mutations in Indian patients with Glanzmann thrombasthenia: localization of mutations affecting cysteine residues in integrin beta3.

Nair S, Li J, Mitchell WB, Mohanty D, Coller BS, French DL.

Thromb Haemost. 2002 Sep;88(3):503-9.PMID: 12353082 [PubMed - indexed for MEDLINE]Related articles

Effects of abciximab on the acute pathology of blood vessels after arterial stenting in nonhuman primates.

Palmerini T, Nedelman MA, Scudder LE, Nakada MT, Jordan RE, Smyth S, Gordon RE, Fallon JT, Coller BS.

J Am Coll Cardiol. 2002 Jul 17;40(2):360-6.PMID: 12106945 [PubMed - indexed for MEDLINE]Related articles

Professing and living the oath: teaching medicine as a profession.

Coller BS, Klotman P, Smith LG.

Am J Med. 2002 Jun 15;112(9):744-8. No abstract available. PMID: 12079723 [PubMed - indexed for MEDLINE]Related articles

Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm.

Turhan A, Weiss LA, Mohandas N, Coller BS, Frenette PS.

Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3047-51.PMID: 11880644 [PubMed - indexed for MEDLINE]Related articlesFree article

Emerging Therapies: Spectrum of Applications of Monoclonal Antibody Therapy.

Waldmann TA, Levy R, Coller BS.

Hematology Am Soc Hematol Educ Program. 2000:394-408.PMID: 11701553 [PubMed - as supplied by publisher]Related articlesFree article

A hamster antibody to the mouse fibrinogen gamma chain inhibits platelet-fibrinogen interactions and FXIIIa-mediated fibrin cross-linking, and facilitates thrombolysis.

Jirousková M, Smyth SS, Kudryk B, Coller BS.

Thromb Haemost. 2001 Oct;86(4):1047-56.PMID: 11686323 [PubMed - indexed for MEDLINE]Related articles

Dynamic platelet accumulation at the site of the occluded middle cerebral artery and in downstream microvessels is associated with loss of microvascular integrity after embolic middle cerebral artery occlusion.

Zhang ZG, Zhang L, Tsang W, Goussev A, Powers C, Ho KL, Morris D, Smyth SS, Coller BS, Chopp M.

Brain Res. 2001 Sep 7;912(2):181-94.PMID: 11532435 [PubMed - indexed for MEDLINE]Related articles

Variable protection of beta 3-integrin--deficient mice from thrombosis initiated by different mechanisms.

Smyth SS, Reis ED, Väänänen H, Zhang W, Coller BS.

Blood. 2001 Aug 15;98(4):1055-62.PMID: 11493451 [PubMed - indexed for MEDLINE]Related articlesFree article

Anti-GPIIb/IIIa drugs: current strategies and future directions.

Coller BS.

Thromb Haemost. 2001 Jul;86(1):427-43. Review.PMID: 11487034 [PubMed - indexed for MEDLINE]Related articles

Platelet adhesion to fibrinogen coated at various densities.

Jirousková M, Coller BS.

Ann N Y Acad Sci. 2001;936:464-5.PMID: 11460503 [PubMed - indexed for MEDLINE]Related articles

Beta(3)-integrin-deficient mice but not P-selectin-deficient mice develop intimal hyperplasia after vascular injury: correlation with leukocyte recruitment to adherent platelets 1 hour after injury.

Smyth SS, Reis ED, Zhang W, Fallon JT, Gordon RE, Coller BS.

Circulation. 2001 May 22;103(20):2501-7.PMID: 11369692 [PubMed - indexed for MEDLINE]Related articlesFree article

Structure and function of murine alphaIIbbeta3 (GPIIb/IIIa): studies using monoclonal antibodies and beta3-null mice,.

Smyth SS, Tsakiris DA, Scudder LE, Coller BS.

Thromb Haemost. 2000 Dec;84(6):1103-8.PMID: 11154120 [PubMed - indexed for MEDLINE]Related articles