PubMed

Longitudinal progression of sporadic Parkinson's disease: a multi-tracer positron emission tomography study.

Nandhagopal R, Kuramoto L, Schulzer M, Mak E, Cragg J, Lee CS, McKenzie J, McCormick S, Samii A, Troiano A, Ruth TJ, Sossi V, de la Fuente-Fernandez R, Calne DB, Stoessl AJ.

Brain. 2009 Nov;132(Pt 11):2970-9. Epub 2009 Aug 18.PMID: 19690093 [PubMed - in process]Related articles

DCTN1 mutations in Perry syndrome.

Farrer MJ, Hulihan MM, Kachergus JM, Dächsel JC, Stoessl AJ, Grantier LL, Calne S, Calne DB, Lechevalier B, Chapon F, Tsuboi Y, Yamada T, Gutmann L, Elibol B, Bhatia KP, Wider C, Vilariño-Güell C, Ross OA, Brown LA, Castanedes-Casey M, Dickson DW, Wszolek ZK.

Nat Genet. 2009 Feb;41(2):163-5. Epub 2009 Jan 11.PMID: 19136952 [PubMed - indexed for MEDLINE]Related articles

Genetic factors influencing age at onset in LRRK2-linked Parkinson disease.

Golub Y, Berg D, Calne DB, Pfeiffer RF, Uitti RJ, Stoessl AJ, Wszolek ZK, Farrer MJ, Mueller JC, Gasser T, Fuchs J.

Parkinsonism Relat Disord. 2009 Aug;15(7):539-41. Epub 2008 Nov 28.PMID: 19041274 [PubMed - indexed for MEDLINE]Related articles

Pallidonigral TDP-43 pathology in Perry syndrome.

Wider C, Dickson DW, Stoessl AJ, Tsuboi Y, Chapon F, Gutmann L, Lechevalier B, Calne DB, Personett DA, Hulihan M, Kachergus J, Rademakers R, Baker MC, Grantier LL, Sujith OK, Brown L, Calne S, Farrer MJ, Wszolek ZK.

Parkinsonism Relat Disord. 2009 May;15(4):281-6. Epub 2008 Aug 23.PMID: 18723384 [PubMed - indexed for MEDLINE]Related articles

The role of the Lewy body in idiopathic Parkinsonism.

de la Fuente-Fernandez R, Schulzer M, Mak E, Kishore A, Calne DB.

Parkinsonism Relat Disord. 1998 Aug;4(2):73-7.PMID: 18591092 [PubMed - in process]Related articles

German-Canadian family (family A) with parkinsonism, amyotrophy, and dementia - Longitudinal observations.

Wszolek ZK, Vieregge P, Uitti RJ, Gasser T, Yasuhara O, McGeer P, Berry K, Calne DB, Vingerhoets FJ, Klein C, Pfeiffer RF.

Parkinsonism Relat Disord. 1997 Nov;3(3):125-39.PMID: 18591067 [PubMed - in process]Related articles

Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms.

Melquist S, Craig DW, Huentelman MJ, Crook R, Pearson JV, Baker M, Zismann VL, Gass J, Adamson J, Szelinger S, Corneveaux J, Cannon A, Coon KD, Lincoln S, Adler C, Tuite P, Calne DB, Bigio EH, Uitti RJ, Wszolek ZK, Golbe LI, Caselli RJ, Graff-Radford N, Litvan I, Farrer MJ, Dickson DW, Hutton M, Stephan DA.

Am J Hum Genet. 2007 Apr;80(4):769-78. Epub 2007 Mar 8.PMID: 17357082 [PubMed - indexed for MEDLINE]Related articlesFree article

The natural history of neurological manganism over 18 years.

Huang CC, Chu NS, Lu CS, Chen RS, Schulzer M, Calne DB.

Parkinsonism Relat Disord. 2007 Apr;13(3):143-5. Epub 2006 Oct 17.PMID: 17052946 [PubMed - indexed for MEDLINE]Related articles

Autosomal dominant dystonia-plus with cerebral calcifications.

Wszolek ZK, Baba Y, Mackenzie IR, Uitti RJ, Strongosky AJ, Broderick DF, Baker MC, Melquist S, Hutton ML, Tsuboi Y, Allanson JE, Carr J, Kumar A, Calne SM, Miklossy J, McGeer PL, Calne DB, Stoessl AJ.

Neurology. 2006 Aug 22;67(4):620-5.PMID: 16924015 [PubMed - indexed for MEDLINE]Related articles

PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation.

Adams JR, van Netten H, Schulzer M, Mak E, Mckenzie J, Strongosky A, Sossi V, Ruth TJ, Lee CS, Farrer M, Gasser T, Uitti RJ, Calne DB, Wszolek ZK, Stoessl AJ.

Brain. 2005 Dec;128(Pt 12):2777-85. Epub 2005 Aug 4.PMID: 16081470 [PubMed - indexed for MEDLINE]Related articlesFree article

A reassessment of the Lewy body.

Au WL, Calne DB.

Acta Neurol Taiwan. 2005 Jun;14(2):40-7. Review.PMID: 16008161 [PubMed - indexed for MEDLINE]Related articles

Severe vascular disturbance in a case of familial brain calcinosis.

Miklossy J, Mackenzie IR, Dorovini-Zis K, Calne DB, Wszolek ZK, Klegeris A, McGeer PL.

Acta Neuropathol. 2005 Jun;109(6):643-53. Epub 2005 Jun 4.PMID: 15937691 [PubMed - indexed for MEDLINE]Related articles

Genetic heterogeneity in familial idiopathic basal ganglia calcification (Fahr disease).

Oliveira JR, Spiteri E, Sobrido MJ, Hopfer S, Klepper J, Voit T, Gilbert J, Wszolek ZK, Calne DB, Stoessl AJ, Hutton M, Manyam BV, Boller F, Baquero M, Geschwind DH.

Neurology. 2004 Dec 14;63(11):2165-7.PMID: 15596772 [PubMed - indexed for MEDLINE]Related articles

Lack of regional selectivity during the progression of Parkinson disease: implications for pathogenesis.

Lee CS, Schulzer M, de la Fuente-Fernández R, Mak E, Kuramoto L, Sossi V, Ruth TJ, Calne DB, Stoessl AJ.

Arch Neurol. 2004 Dec;61(12):1920-5.PMID: 15596613 [PubMed - indexed for MEDLINE]Related articlesFree article

Is the neuropathological 'gold standard' diagnosis dead? Implications of clinicopathological findings in an autosomal dominant neurodegenerative disorder.

Uitti RJ, Calne DB, Dickson DW, Wszolek ZK.

Parkinsonism Relat Disord. 2004 Dec;10(8):461-3.PMID: 15542004 [PubMed - indexed for MEDLINE]Related articles

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.

Zimprich A, Biskup S, Leitner P, Lichtner P, Farrer M, Lincoln S, Kachergus J, Hulihan M, Uitti RJ, Calne DB, Stoessl AJ, Pfeiffer RF, Patenge N, Carbajal IC, Vieregge P, Asmus F, Müller-Myhsok B, Dickson DW, Meitinger T, Strom TM, Wszolek ZK, Gasser T.

Neuron. 2004 Nov 18;44(4):601-7.PMID: 15541309 [PubMed - indexed for MEDLINE]Related articles

Functional imaging in Tourette's syndrome.

Adams JR, Troiano AR, Calne DB.

J Neural Transm. 2004 Oct;111(10-11):1495-506. Epub 2004 Jun 30. Review.PMID: 15480848 [PubMed - indexed for MEDLINE]Related articles

A tribute for Prof. Dr. Melvin D. Yahr, M.D. (1917-2004).

Riederer PF, Hirsch E, Youdim MB, Calne DB.

J Neural Transm. 2004 Oct;111(10-11):1205-8. No abstract available. PMID: 15480833 [PubMed - indexed for MEDLINE]Related articles

Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: implications for dyskinesias.

de la Fuente-Fernández R, Sossi V, Huang Z, Furtado S, Lu JQ, Calne DB, Ruth TJ, Stoessl AJ.

Brain. 2004 Dec;127(Pt 12):2747-54. Epub 2004 Aug 25.PMID: 15329355 [PubMed - indexed for MEDLINE]Related articlesFree article

Clustering of Parkinson disease: shared cause or coincidence?

Kumar A, Calne SM, Schulzer M, Mak E, Wszolek Z, Van Netten C, Tsui JK, Stoessl AJ, Calne DB.

Arch Neurol. 2004 Jul;61(7):1057-60.PMID: 15262735 [PubMed - indexed for MEDLINE]Related articlesFree article

Profile of families with parkinsonism-predominant spinocerebellar ataxia type 2 (SCA2).

Furtado S, Payami H, Lockhart PJ, Hanson M, Nutt JG, Singleton AA, Singleton A, Bower J, Utti RJ, Bird TD, de la Fuente-Fernandez R, Tsuboi Y, Klimek ML, Suchowersky O, Hardy J, Calne DB, Wszolek ZK, Farrer M, Gwinn-Hardy K, Stoessl AJ.

Mov Disord. 2004 Jun;19(6):622-9. Review.PMID: 15197699 [PubMed - indexed for MEDLINE]Related articles

The neuromythology of Parkinson's Disease.

Calne DB, Mizuno Y.

Parkinsonism Relat Disord. 2004 Jul;10(5):319-22. Review.PMID: 15196512 [PubMed - indexed for MEDLINE]Related articles

Autosomal dominant parkinsonism associated with variable synuclein and tau pathology.

Wszolek ZK, Pfeiffer RF, Tsuboi Y, Uitti RJ, McComb RD, Stoessl AJ, Strongosky AJ, Zimprich A, Müller-Myhsok B, Farrer MJ, Gasser T, Calne DB, Dickson DW.

Neurology. 2004 May 11;62(9):1619-22.PMID: 15136696 [PubMed - indexed for MEDLINE]Related articles

Presynaptic mechanisms of motor fluctuations in Parkinson's disease: a probabilistic model.

de la Fuente-Fernández R, Schulzer M, Mak E, Calne DB, Stoessl AJ.

Brain. 2004 Apr;127(Pt 4):888-99. Epub 2004 Feb 11.PMID: 14960500 [PubMed - indexed for MEDLINE]Related articlesFree article

The PARK8 locus in autosomal dominant parkinsonism: confirmation of linkage and further delineation of the disease-containing interval.

Zimprich A, Müller-Myhsok B, Farrer M, Leitner P, Sharma M, Hulihan M, Lockhart P, Strongosky A, Kachergus J, Calne DB, Stoessl J, Uitti RJ, Pfeiffer RF, Trenkwalder C, Homann N, Ott E, Wenzel K, Asmus F, Hardy J, Wszolek Z, Gasser T.

Am J Hum Genet. 2004 Jan;74(1):11-9. Epub 2003 Dec 19. Erratum in: Am J Hum Genet. 2004 Sep;75(3):534. PMID: 14691730 [PubMed - indexed for MEDLINE]Related articlesFree article

Protective effects of intracerebral adenoviral-mediated GDNF gene transfer in a rat model of Parkinson's disease.

Chen X, Liu W, Guoyuan Y, Liu Z, Smith S, Calne DB, Chen S.

Parkinsonism Relat Disord. 2003 Oct;10(1):1-7.PMID: 14499199 [PubMed - indexed for MEDLINE]Related articles

Determination of an occupational exposure guideline for manganese using the benchmark method.

Clewell HJ, Lawrence GA, Calne DB, Crump KS.

Risk Anal. 2003 Oct;23(5):1031-46.PMID: 12969417 [PubMed - indexed for MEDLINE]Related articles

VMAT2 binding is elevated in dopa-responsive dystonia: visualizing empty vesicles by PET.

De La Fuente-Fernández R, Furtado S, Guttman M, Furukawa Y, Lee CS, Calne DB, Ruth TJ, Stoessl AJ.

Synapse. 2003 Jul;49(1):20-8.PMID: 12710012 [PubMed - indexed for MEDLINE]Related articles

Clinical presentation of primary progressive multiple sclerosis 10 years after the incidental finding of typical magnetic resonance imaging brain lesions: the subclinical stage of primary progressive multiple sclerosis may last 10 years.

McDonnell GV, Cabrera-Gomez J, Calne DB, Li DK, Oger J.

Mult Scler. 2003 Mar;9(2):204-9.PMID: 12708816 [PubMed - indexed for MEDLINE]Related articles

Familial and sporadic Parkinson's disease usually display the same clinical features.

Carr J, de la Fuente-Fernández R, Schulzer M, Mak E, Calne SM, Calne DB.

Parkinsonism Relat Disord. 2003 Mar;9(4):201-4.PMID: 12618054 [PubMed - indexed for MEDLINE]Related articles

Age and severity of nigrostriatal damage at onset of Parkinson's disease.

De La Fuente-Fernández R, Lim AS, Sossi V, Adam MJ, Ruth TJ, Calne DB, Stoessl AJ, Lee CS.

Synapse. 2003 Feb;47(2):152-8.PMID: 12454953 [PubMed - indexed for MEDLINE]Related articles

SCA-2 presenting as parkinsonism in an Alberta family: clinical, genetic, and PET findings.

Furtado S, Farrer M, Tsuboi Y, Klimek ML, de la Fuente-Fernández R, Hussey J, Lockhart P, Calne DB, Suchowersky O, Stoessl AJ, Wszolek ZK.

Neurology. 2002 Nov 26;59(10):1625-7.PMID: 12451209 [PubMed - indexed for MEDLINE]Related articles

Parkinson's disease over the last 100 years.

Calne DB.

Adv Neurol. 2003;91:1-8. No abstract available. PMID: 12442659 [PubMed - indexed for MEDLINE]Related articles

Dopamine release in human ventral striatum and expectation of reward.

de la Fuente-Fernández R, Phillips AG, Zamburlini M, Sossi V, Calne DB, Ruth TJ, Stoessl AJ.

Behav Brain Res. 2002 Nov 15;136(2):359-63.PMID: 12429397 [PubMed - indexed for MEDLINE]Related articles

[18F]-Dopa positron emission tomography imaging in early-stage, non-parkin juvenile parkinsonism.

Pal PK, Leung J, Hedrich K, Samii A, Lieberman A, Nausieda PA, Calne DB, Breakefield XO, Klein C, Stoessl AJ.

Mov Disord. 2002 Jul;17(4):789-94.PMID: 12210877 [PubMed - indexed for MEDLINE]Related articles

Evidence for environmental causation of Parkinson's disease.

de la Fuente-Fernández R, Calne DB.

Parkinsonism Relat Disord. 2002 Mar;8(4):235-41.PMID: 12039417 [PubMed - indexed for MEDLINE]Related articles

Synthetic dopamine agonists.

Calne DB.

Expert Opin Pharmacother. 2002 Apr;3(4):363-4. Review. No abstract available. PMID: 11934338 [PubMed - indexed for MEDLINE]Related articles

Apomorphine-induced changes in synaptic dopamine levels: positron emission tomography evidence for presynaptic inhibition.

de La Fuente-Fernández R, Lim AS, Sossi V, Holden JE, Calne DB, Ruth TJ, Stoessl AJ.

J Cereb Blood Flow Metab. 2001 Oct;21(10):1151-9.PMID: 11598492 [PubMed - indexed for MEDLINE]Related articlesFree article

Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease.

de la Fuente-Fernández R, Ruth TJ, Sossi V, Schulzer M, Calne DB, Stoessl AJ.

Science. 2001 Aug 10;293(5532):1164-6.PMID: 11498597 [PubMed - indexed for MEDLINE]Related articlesFree article

Positron emission tomography of dopamine pathways in familial Parkinsonian syndromes.

Pal PK, Wszolek ZK, Uitti R, Markopoulou K, Calne SM, Stoessl AJ, Calne DB.

Parkinsonism Relat Disord. 2001 Sep;8(1):51-6. Review.PMID: 11472880 [PubMed - indexed for MEDLINE]Related articles

The long-term response to levodopa in dopa-responsive dystonia.

Hwang WJ, Calne DB, Tsui JK, de la Fuente-Fernández R.

Parkinsonism Relat Disord. 2001 Sep;8(1):1-5.PMID: 11472874 [PubMed - indexed for MEDLINE]Related articles

Transdermal dopaminergic D(2) receptor agonist therapy in Parkinson's disease with N-0923 TDS: a double-blind, placebo-controlled study.

Hutton JT, Metman LV, Chase TN, Juncos JL, Koller WC, Pahwa R, LeWitt PA, Samii A, Tsui JK, Calne DB, Waters CH, Calabrese VP, Bennett JP, Barrett R, Morris JL.

Mov Disord. 2001 May;16(3):459-63.PMID: 11391739 [PubMed - indexed for MEDLINE]Related articles

Daytime somnolence in patients with Parkinson's disease.

Sanjiv CC, Schulzer M, Mak E, Fleming J, Martin WR, Brown T, Calne SM, Tsui J, Stoessl AJ, Lee CS, Calne DB.

Parkinsonism Relat Disord. 2001 Oct;7(4):283-286.PMID: 11344010 [PubMed - as supplied by publisher]Related articles

Familial aggregation of Parkinson's disease.

de la Fuente-Fernández R, Calne DB.

N Engl J Med. 2001 Apr 12;344(15):1168. No abstract available. PMID: 11302144 [PubMed - indexed for MEDLINE]Related articles

Biochemical variations in the synaptic level of dopamine precede motor fluctuations in Parkinson's disease: PET evidence of increased dopamine turnover.

de la Fuente-Fernández R, Lu JQ, Sossi V, Jivan S, Schulzer M, Holden JE, Lee CS, Ruth TJ, Calne DB, Stoessl AJ.

Ann Neurol. 2001 Mar;49(3):298-303.PMID: 11261503 [PubMed - indexed for MEDLINE]Related articles

Parkinson's disease is not one disease.

Calne DB.

Parkinsonism Relat Disord. 2000 Nov 1;7(1):3-7. No abstract available. PMID: 11008190 [PubMed - as supplied by publisher]Related articles

Long term outcome of unilateral pallidotomy: follow up of 15 patients for 3 years.

Pal PK, Samii A, Kishore A, Schulzer M, Mak E, Yardley S, Turnbull IM, Calne DB.

J Neurol Neurosurg Psychiatry. 2000 Sep;69(3):337-44.PMID: 10945808 [PubMed - indexed for MEDLINE]Related articlesFree article

From Wilhelm von Humboldt to Hitler-are prominent people more prone to have Parkinson's disease?

Horowski R, Horowski L, Calne SM, Calne DB.

Parkinsonism Relat Disord. 2000 Oct 1;6(4):205-214.PMID: 10900395 [PubMed - as supplied by publisher]Related articles

Nigrostriatal dopamine system and motor lateralization.

de la Fuente-Fernández R, Kishore A, Calne DB, Ruth TJ, Stoessl AJ.

Behav Brain Res. 2000 Jul;112(1-2):63-8.PMID: 10862936 [PubMed - indexed for MEDLINE]Related articles

Evidence for impaired presynaptic dopamine function in parkinsonian patients with motor fluctuations.

de la Fuente-Fernández R, Pal PK, Vingerhoets FJ, Kishore A, Schulzer M, Mak EK, Ruth TJ, Snow BJ, Calne DB, Stoessl AJ.

J Neural Transm. 2000;107(1):49-57.PMID: 10809403 [PubMed - indexed for MEDLINE]Related articles