PubMed

Calcium-activated calpain-2 is a mediator of beta cell dysfunction and apoptosis in type 2 diabetes.

Huang CJ, Gurlo T, Haataja L, Costes S, Daval M, Ryazantsev S, Wu X, Butler AE, Butler PC.

J Biol Chem. 2009 Oct 28. [Epub ahead of print]PMID: 19861418 [PubMed - as supplied by publisher]Related articlesFree article

Relationship between fractional pancreatic beta cell area and fasting plasma glucose concentration in monkeys.

Saisho Y, Butler AE, Manesso E, Galasso R, Zhang L, Gurlo T, Toffolo GM, Cobelli C, Kavanagh K, Wagner JD, Butler PC.

Diabetologia. 2009 Oct 22. [Epub ahead of print]PMID: 19847395 [PubMed - as supplied by publisher]Related articles

Pancreatic duct replication is increased with obesity and type 2 diabetes in humans.

Butler AE, Galasso R, Matveyenko A, Rizza RA, Dry S, Butler PC.

Diabetologia. 2009 Oct 21. [Epub ahead of print]PMID: 19844672 [PubMed - as supplied by publisher]Related articles

Dynamics of beta-cell turnover: evidence for beta-cell turnover and regeneration from sources of beta-cells other than beta-cell replication in the HIP rat.

Manesso E, Toffolo GM, Saisho Y, Butler AE, Matveyenko AV, Cobelli C, Butler PC.

Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E323-30. Epub 2009 May 26.PMID: 19470833 [PubMed - indexed for MEDLINE]Related articles

Beneficial endocrine but adverse exocrine effects of sitagliptin in the human islet amyloid polypeptide transgenic rat model of type 2 diabetes: interactions with metformin.

Matveyenko AV, Dry S, Cox HI, Moshtaghian A, Gurlo T, Galasso R, Butler AE, Butler PC.

Diabetes. 2009 Jul;58(7):1604-15. Epub 2009 Apr 29.PMID: 19403868 [PubMed - indexed for MEDLINE]Related articlesFree article

Successful versus failed adaptation to high-fat diet-induced insulin resistance: the role of IAPP-induced beta-cell endoplasmic reticulum stress.

Matveyenko AV, Gurlo T, Daval M, Butler AE, Butler PC.

Diabetes. 2009 Apr;58(4):906-16. Epub 2009 Jan 16.PMID: 19151199 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship between pancreatic vesicular monoamine transporter 2 (VMAT2) and insulin expression in human pancreas.

Saisho Y, Harris PE, Butler AE, Galasso R, Gurlo T, Rizza RA, Butler PC.

J Mol Histol. 2008 Oct;39(5):543-51. Epub 2008 Sep 13.PMID: 18791800 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic fat content and beta-cell function in men with and without type 2 diabetes: response to Tushuizen et al.

Saisho Y, Butler AE, Butler PC.

Diabetes Care. 2008 May;31(5):e38; author reply e39. No abstract available. PMID: 18445718 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans.

Meier JJ, Butler AE, Saisho Y, Monchamp T, Galasso R, Bhushan A, Rizza RA, Butler PC.

Diabetes. 2008 Jun;57(6):1584-94. Epub 2008 Mar 11.PMID: 18334605 [PubMed - indexed for MEDLINE]Related articlesFree article

The replication of beta cells in normal physiology, in disease and for therapy.

Butler PC, Meier JJ, Butler AE, Bhushan A.

Nat Clin Pract Endocrinol Metab. 2007 Nov;3(11):758-68. Review.PMID: 17955017 [PubMed - indexed for MEDLINE]Related articles

Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide.

Huang CJ, Haataja L, Gurlo T, Butler AE, Wu X, Soeller WC, Butler PC.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1656-62. Epub 2007 Oct 2.PMID: 17911343 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreas volumes in humans from birth to age one hundred taking into account sex, obesity, and presence of type-2 diabetes.

Saisho Y, Butler AE, Meier JJ, Monchamp T, Allen-Auerbach M, Rizza RA, Butler PC.

Clin Anat. 2007 Nov;20(8):933-42.PMID: 17879305 [PubMed - indexed for MEDLINE]Related articlesFree article

Modestly increased beta cell apoptosis but no increased beta cell replication in recent-onset type 1 diabetic patients who died of diabetic ketoacidosis.

Butler AE, Galasso R, Meier JJ, Basu R, Rizza RA, Butler PC.

Diabetologia. 2007 Nov;50(11):2323-31. Epub 2007 Sep 6.PMID: 17805509 [PubMed - indexed for MEDLINE]Related articles

High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes.

Huang CJ, Lin CY, Haataja L, Gurlo T, Butler AE, Rizza RA, Butler PC.

Diabetes. 2007 Aug;56(8):2016-27. Epub 2007 May 2.PMID: 17475933 [PubMed - indexed for MEDLINE]Related articlesFree article

Hematopoietic stem cells derived from adult donors are not a source of pancreatic beta-cells in adult nondiabetic humans.

Butler AE, Huang A, Rao PN, Bhushan A, Hogan WJ, Rizza RA, Butler PC.

Diabetes. 2007 Jul;56(7):1810-6. Epub 2007 Apr 24.PMID: 17456852 [PubMed - indexed for MEDLINE]Related articlesFree article

Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice.

Lin CY, Gurlo T, Kayed R, Butler AE, Haataja L, Glabe CG, Butler PC.

Diabetes. 2007 May;56(5):1324-32. Epub 2007 Mar 12.PMID: 17353506 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased islet beta cell replication adjacent to intrapancreatic gastrinomas in humans.

Meier JJ, Butler AE, Galasso R, Rizza RA, Butler PC.

Diabetologia. 2006 Nov;49(11):2689-96. Epub 2006 Sep 23.PMID: 17016695 [PubMed - indexed for MEDLINE]Related articles

Direct evidence of attempted beta cell regeneration in an 89-year-old patient with recent-onset type 1 diabetes.

Meier JJ, Lin JC, Butler AE, Galasso R, Martinez DS, Butler PC.

Diabetologia. 2006 Aug;49(8):1838-44. Epub 2006 Jun 27.PMID: 16802132 [PubMed - indexed for MEDLINE]Related articles

Hyperinsulinemic hypoglycemia after gastric bypass surgery is not accompanied by islet hyperplasia or increased beta-cell turnover.

Meier JJ, Butler AE, Galasso R, Butler PC.

Diabetes Care. 2006 Jul;29(7):1554-9.PMID: 16801578 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship between beta-cell mass and fasting blood glucose concentration in humans.

Ritzel RA, Butler AE, Rizza RA, Veldhuis JD, Butler PC.

Diabetes Care. 2006 Mar;29(3):717-8. No abstract available. PMID: 16505537 [PubMed - indexed for MEDLINE]Related articlesFree article

Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?

Meier JJ, Bhushan A, Butler AE, Rizza RA, Butler PC.

Diabetologia. 2005 Nov;48(11):2221-8. Epub 2005 Oct 5.PMID: 16205882 [PubMed - indexed for MEDLINE]Related articles

Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes.

Butler AE, Jang J, Gurlo T, Carty MD, Soeller WC, Butler PC.

Diabetes. 2004 Jun;53(6):1509-16.PMID: 15161755 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid.

Butler AE, Janson J, Soeller WC, Butler PC.

Diabetes. 2003 Sep;52(9):2304-14.PMID: 12941770 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes.

Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC.

Diabetes. 2003 Jan;52(1):102-10.PMID: 12502499 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet amyloid polypeptide in human insulinomas. Evidence for intracellular amyloidogenesis.

O'Brien TD, Butler AE, Roche PC, Johnson KH, Butler PC.

Diabetes. 1994 Feb;43(2):329-36.PMID: 8288058 [PubMed - indexed for MEDLINE]Related articles

Lymphocytic mastopathy associated with infiltrating lobular breast carcinoma.

Chetty R, Butler AE.

J Clin Pathol. 1993 Apr;46(4):376-7.PMID: 8496398 [PubMed - indexed for MEDLINE]Related articlesFree article

Lymphoepithelioma-like carcinoma of the lung.

Butler AE, Colby TV, Weiss L, Lombard C.

Am J Surg Pathol. 1989 Aug;13(8):632-9.PMID: 2546459 [PubMed - indexed for MEDLINE]Related articles

Analysis of lymphoepithelioma and lymphoepithelioma-like carcinomas for Epstein-Barr viral genomes by in situ hybridization.

Weiss LM, Movahed LA, Butler AE, Swanson SA, Frierson HF Jr, Cooper PH, Colby TV, Mills SE.

Am J Surg Pathol. 1989 Aug;13(8):625-31.PMID: 2546458 [PubMed - indexed for MEDLINE]Related articles

Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia.

Larson RA, Kondo K, Vardiman JW, Butler AE, Golomb HM, Rowley JD.

Am J Med. 1984 May;76(5):827-41.PMID: 6586073 [PubMed - indexed for MEDLINE]Related articles

Ultrastructural characterization of de novo and secondary leukemias.

Butler AE, Vardiman JW, Golomb HM.

Virchows Arch B Cell Pathol Incl Mol Pathol. 1982;39(3):239-57.PMID: 6126030 [PubMed - indexed for MEDLINE]Related articles