PubMed

A role for the gut-to-brain GLP-1-dependent axis in the control of metabolism.

Burcelin R, Serino M, Cabou C.

Curr Opin Pharmacol. 2009 Sep 30. [Epub ahead of print]PMID: 19800290 [PubMed - as supplied by publisher]Related articles

An adiponectin-like molecule with antidiabetic properties.

Sulpice T, Prunet-Marcassus B, Molveaux C, Cani PD, Vitte PA, Graber P, Dreano M, Burcelin R.

Endocrinology. 2009 Oct;150(10):4493-501. Epub 2009 Jul 16.PMID: 19608652 [PubMed - indexed for MEDLINE]Related articles

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.

Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, Tarasov AI, Carzaniga R, Kronenberger K, Taneja TK, da Silva Xavier G, Libert S, Froguel P, Scharfmann R, Stetsyuk V, Ravassard P, Parker H, Gribble FM, Reimann F, Sladek R, Hughes SJ, Johnson PR, Masseboeuf M, Burcelin R, Baldwin SA, Liu M, Lara-Lemus R, Arvan P, Schuit FC, Wheeler MB, Chimienti F, Rutter GA.

Diabetes. 2009 Sep;58(9):2070-83. Epub 2009 Jun 19.PMID: 19542200 [PubMed - indexed for MEDLINE]Related articles

Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis.

Deveaux V, Cadoudal T, Ichigotani Y, Teixeira-Clerc F, Louvet A, Manin S, Nhieu JT, Belot MP, Zimmer A, Even P, Cani PD, Knauf C, Burcelin R, Bertola A, Le Marchand-Brustel Y, Gual P, Mallat A, Lotersztajn S.

PLoS One. 2009 Jun 9;4(6):e5844.PMID: 19513120 [PubMed - indexed for MEDLINE]Related articlesFree article

The gut microbiota ecology: a new opportunity for the treatment of metabolic diseases?

Burcelin R, Luche E, Serino M, Amar J.

Front Biosci. 2009 Jun 1;14:5107-17. Review.PMID: 19482607 [PubMed - indexed for MEDLINE]Related articles

Intestinal microflora and metabolic diseases.

Serino M, Luche E, Chabo C, Amar J, Burcelin R.

Diabetes Metab. 2009 Sep;35(4):262-72. Epub 2009 May 5.PMID: 19419895 [PubMed - in process]Related articles

n-3 fatty acids and rosiglitazone improve insulin sensitivity through additive stimulatory effects on muscle glycogen synthesis in mice fed a high-fat diet.

Kuda O, Jelenik T, Jilkova Z, Flachs P, Rossmeisl M, Hensler M, Kazdova L, Ogston N, Baranowski M, Gorski J, Janovska P, Kus V, Polak J, Mohamed-Ali V, Burcelin R, Cinti S, Bryhn M, Kopecky J.

Diabetologia. 2009 May;52(5):941-51. Epub 2009 Mar 11. Erratum in: Diabetologia. 2009 Jul;52(7):1455. PMID: 19277604 [PubMed - indexed for MEDLINE]Related articles

The inflammatory receptor CD40 is expressed on human adipocytes: contribution to crosstalk between lymphocytes and adipocytes.

Poggi M, Jager J, Paulmyer-Lacroix O, Peiretti F, Gremeaux T, Verdier M, Grino M, Stepanian A, Msika S, Burcelin R, de Prost D, Tanti JF, Alessi MC.

Diabetologia. 2009 Jun;52(6):1152-63. Epub 2009 Jan 31.PMID: 19183933 [PubMed - indexed for MEDLINE]Related articles

Estrogens protect against high-fat diet-induced insulin resistance and glucose intolerance in mice.

Riant E, Waget A, Cogo H, Arnal JF, Burcelin R, Gourdy P.

Endocrinology. 2009 May;150(5):2109-17. Epub 2009 Jan 22.PMID: 19164473 [PubMed - indexed for MEDLINE]Related articles

Apelin stimulates glucose utilization in normal and obese insulin-resistant mice.

Dray C, Knauf C, Daviaud D, Waget A, Boucher J, Buléon M, Cani PD, Attané C, Guigné C, Carpéné C, Burcelin R, Castan-Laurell I, Valet P.

Cell Metab. 2008 Nov;8(5):437-45.PMID: 19046574 [PubMed - indexed for MEDLINE]Related articles

What is known, new and controversial about GLP-1? Minutes of the 1st European GLP-1 Club Meeting, Marseille, 28-29 May 2008.

Burcelin R; EuCSGLP-1.

Diabetes Metab. 2008 Dec;34(6 Pt 1):627-30. Epub 2008 Nov 21.PMID: 19026584 [PubMed - indexed for MEDLINE]Related articles

Pancreatic alpha-cell dysfunction in diabetes.

Burcelin R, Knauf C, Cani PD.

Diabetes Metab. 2008 Feb;34 Suppl 2:S49-55. Review.PMID: 18640586 [PubMed - indexed for MEDLINE]Related articlesFree article

Brain glucagon-like peptide-1 regulates arterial blood flow, heart rate, and insulin sensitivity.

Cabou C, Campistron G, Marsollier N, Leloup C, Cruciani-Guglielmacci C, Pénicaud L, Drucker DJ, Magnan C, Burcelin R.

Diabetes. 2008 Oct;57(10):2577-87. Epub 2008 Jul 15.PMID: 18633100 [PubMed - indexed for MEDLINE]Related articlesFree article

Brain glucagon-like peptide 1 signaling controls the onset of high-fat diet-induced insulin resistance and reduces energy expenditure.

Knauf C, Cani PD, Ait-Belgnaoui A, Benani A, Dray C, Cabou C, Colom A, Uldry M, Rastrelli S, Sabatier E, Godet N, Waget A, Pénicaud L, Valet P, Burcelin R.

Endocrinology. 2008 Oct;149(10):4768-77. Epub 2008 Jun 12.PMID: 18556349 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of central nervous system glucagon-like Peptide-1 receptors in enteric glucose sensing.

Knauf C, Cani PD, Kim DH, Iglesias MA, Chabo C, Waget A, Colom A, Rastrelli S, Delzenne NM, Drucker DJ, Seeley RJ, Burcelin R.

Diabetes. 2008 Oct;57(10):2603-12. Epub 2008 Jun 2.PMID: 18519802 [PubMed - indexed for MEDLINE]Related articlesFree article

Energy intake is associated with endotoxemia in apparently healthy men.

Amar J, Burcelin R, Ruidavets JB, Cani PD, Fauvel J, Alessi MC, Chamontin B, Ferriéres J.

Am J Clin Nutr. 2008 May;87(5):1219-23.PMID: 18469242 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of acute and chronic administration of benzylamine on glucose tolerance in diabetic and obese mice fed on very high-fat diet.

Iffiú-Soltész' Z, Prévot D, Grés S, Bour S, Szökö E, Knauf C, Burcelin R, Fernández-Quintela A, Lomba A, Milagro FI, Carpéné C.

J Physiol Biochem. 2007 Dec;63(4):305-15.PMID: 18457006 [PubMed - indexed for MEDLINE]Related articles

Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice.

Membrez M, Blancher F, Jaquet M, Bibiloni R, Cani PD, Burcelin RG, Corthesy I, Macé K, Chou CJ.

FASEB J. 2008 Jul;22(7):2416-26. Epub 2008 Mar 7.PMID: 18326786 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice.

Cani PD, Bibiloni R, Knauf C, Waget A, Neyrinck AM, Delzenne NM, Burcelin R.

Diabetes. 2008 Jun;57(6):1470-81. Epub 2008 Feb 27.PMID: 18305141 [PubMed - indexed for MEDLINE]Related articlesFree article

[Mitochondrial dysfunction and insulino-resistance: no causal link]

Burcelin R.

Med Sci (Paris). 2008 Feb;24(2):127-8. French. No abstract available. PMID: 18272067 [PubMed - indexed for MEDLINE]Related articles

Leptin and resistin: master enemy adipokines unified in brain to control glucose homeostasis.

Burcelin R.

Endocrinology. 2008 Feb;149(2):443-4. No abstract available. PMID: 18209210 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance in mice lacking neuronal nitric oxide synthase is related to an alpha-adrenergic mechanism.

Turini P, Thalmann S, Jayet PY, Cook S, Mathieu C, Burcelin R, Nicod P, Vollenweider P, Sartori C, Scherrer U.

Swiss Med Wkly. 2007 Dec 22;137(49-50):700-4.PMID: 18197485 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of gut microflora in the development of obesity and insulin resistance following high-fat diet feeding.

Cani PD, Delzenne NM, Amar J, Burcelin R.

Pathol Biol (Paris). 2008 Jul;56(5):305-9. Epub 2008 Jan 30. Review.PMID: 18178333 [PubMed - indexed for MEDLINE]Related articles

Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes.

Pospisilik JA, Knauf C, Joza N, Benit P, Orthofer M, Cani PD, Ebersberger I, Nakashima T, Sarao R, Neely G, Esterbauer H, Kozlov A, Kahn CR, Kroemer G, Rustin P, Burcelin R, Penninger JM.

Cell. 2007 Nov 2;131(3):476-91.PMID: 17981116 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1 and energy homeostasis.

Burcelin R, Cani PD, Knauf C.

J Nutr. 2007 Nov;137(11 Suppl):2534S-2538S. Review.PMID: 17951498 [PubMed - indexed for MEDLINE]Related articlesFree article

FXR-deficiency confers increased susceptibility to torpor.

Cariou B, Bouchaert E, Abdelkarim M, Dumont J, Caron S, Fruchart JC, Burcelin R, Kuipers F, Staels B.

FEBS Lett. 2007 Nov 13;581(27):5191-8. Epub 2007 Oct 12.PMID: 17950284 [PubMed - indexed for MEDLINE]Related articles

Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia.

Cani PD, Neyrinck AM, Fava F, Knauf C, Burcelin RG, Tuohy KM, Gibson GR, Delzenne NM.

Diabetologia. 2007 Nov;50(11):2374-83. Epub 2007 Sep 6.PMID: 17823788 [PubMed - indexed for MEDLINE]Related articles

Lower insulin secretory response to glucose induced by artificial nutrition in children: prolonged and total parenteral nutrition.

Beltrand J, Colomb V, Marinier E, Daubrosse C, Alison M, Burcelin R, Cani PD, Chevenne D, Marchal CL.

Pediatr Res. 2007 Nov;62(5):624-9.PMID: 17805200 [PubMed - indexed for MEDLINE]Related articles

Central insulin regulates heart rate and arterial blood flow: an endothelial nitric oxide synthase-dependent mechanism altered during diabetes.

Cabou C, Cani PD, Campistron G, Knauf C, Mathieu C, Sartori C, Amar J, Scherrer U, Burcelin R.

Diabetes. 2007 Dec;56(12):2872-7. Epub 2007 Sep 5.PMID: 17804761 [PubMed - indexed for MEDLINE]Related articlesFree article

GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion.

Cani PD, Holst JJ, Drucker DJ, Delzenne NM, Thorens B, Burcelin R, Knauf C.

Mol Cell Endocrinol. 2007 Sep 30;276(1-2):18-23. Epub 2007 Jun 29.PMID: 17681422 [PubMed - indexed for MEDLINE]Related articles

Metabolic endotoxemia initiates obesity and insulin resistance.

Cani PD, Amar J, Iglesias MA, Poggi M, Knauf C, Bastelica D, Neyrinck AM, Fava F, Tuohy KM, Chabo C, Waget A, Delmée E, Cousin B, Sulpice T, Chamontin B, Ferrières J, Tanti JF, Gibson GR, Casteilla L, Delzenne NM, Alessi MC, Burcelin R.

Diabetes. 2007 Jul;56(7):1761-72. Epub 2007 Apr 24.PMID: 17456850 [PubMed - indexed for MEDLINE]Related articlesFree article

C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet.

Poggi M, Bastelica D, Gual P, Iglesias MA, Gremeaux T, Knauf C, Peiretti F, Verdier M, Juhan-Vague I, Tanti JF, Burcelin R, Alessi MC.

Diabetologia. 2007 Jun;50(6):1267-76. Epub 2007 Apr 11.PMID: 17426960 [PubMed - indexed for MEDLINE]Related articles

Involvement of cholecystokinin 2 receptor in food intake regulation: hyperphagia and increased fat deposition in cholecystokinin 2 receptor-deficient mice.

Clerc P, Coll Constans MG, Lulka H, Broussaud S, Guigné C, Leung-Theung-Long S, Perrin C, Knauf C, Carpéné C, Pénicaud L, Seva C, Burcelin R, Valet P, Fourmy D, Dufresne M.

Endocrinology. 2007 Mar;148(3):1039-49. Epub 2006 Nov 22.PMID: 17122076 [PubMed - indexed for MEDLINE]Related articlesFree article

Arteries, inflammation and insulin resistance.

Amar J, Perez L, Burcelin R, Chamontin B.

J Hypertens Suppl. 2006 Aug;24(5):S18-20. Review.PMID: 16936531 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain.

Knauf C, Rieusset J, Foretz M, Cani PD, Uldry M, Hosokawa M, Martinez E, Bringart M, Waget A, Kersten S, Desvergne B, Gremlich S, Wahli W, Seydoux J, Delzenne NM, Thorens B, Burcelin R.

Endocrinology. 2006 Sep;147(9):4067-78. Epub 2006 Jun 15.PMID: 16777972 [PubMed - indexed for MEDLINE]Related articlesFree article

Relation between colonic proglucagon expression and metabolic response to oligofructose in high fat diet-fed mice.

Delmée E, Cani PD, Gual G, Knauf C, Burcelin R, Maton N, Delzenne NM.

Life Sci. 2006 Aug 1;79(10):1007-13. Epub 2006 May 20.PMID: 16757002 [PubMed - indexed for MEDLINE]Related articles

Improvement of glucose tolerance and hepatic insulin sensitivity by oligofructose requires a functional glucagon-like peptide 1 receptor.

Cani PD, Knauf C, Iglesias MA, Drucker DJ, Delzenne NM, Burcelin R.

Diabetes. 2006 May;55(5):1484-90.PMID: 16644709 [PubMed - indexed for MEDLINE]Related articlesFree article

[GLP-1 and cerebral detection of glucose, a key mechanism for the regulation of glucose homeostasis]

Burcelin R, Cani PD, Knauf C.

Med Sci (Paris). 2006 Mar;22(3):237-9. French. No abstract available. PMID: 16527198 [PubMed - indexed for MEDLINE]Related articles

Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin.

Andreelli F, Foretz M, Knauf C, Cani PD, Perrin C, Iglesias MA, Pillot B, Bado A, Tronche F, Mithieux G, Vaulont S, Burcelin R, Viollet B.

Endocrinology. 2006 May;147(5):2432-41. Epub 2006 Feb 2.PMID: 16455782 [PubMed - indexed for MEDLINE]Related articlesFree article

Liver-specific deletion of insulin receptor substrate 2 does not impair hepatic glucose and lipid metabolism in mice.

Simmgen M, Knauf C, Lopez M, Choudhury AI, Charalambous M, Cantley J, Bedford DC, Claret M, Iglesias MA, Heffron H, Cani PD, Vidal-Puig A, Burcelin R, Withers DJ.

Diabetologia. 2006 Mar;49(3):552-61. Epub 2006 Jan 11.PMID: 16404553 [PubMed - indexed for MEDLINE]Related articles

Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage.

Knauf C, Cani PD, Perrin C, Iglesias MA, Maury JF, Bernard E, Benhamed F, Grémeaux T, Drucker DJ, Kahn CR, Girard J, Tanti JF, Delzenne NM, Postic C, Burcelin R.

J Clin Invest. 2005 Dec;115(12):3554-63.PMID: 16322793 [PubMed - indexed for MEDLINE]Related articlesFree article

The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform.

Medina-Gomez G, Virtue S, Lelliott C, Boiani R, Campbell M, Christodoulides C, Perrin C, Jimenez-Linan M, Blount M, Dixon J, Zahn D, Thresher RR, Aparicio S, Carlton M, Colledge WH, Kettunen MI, Seppänen-Laakso T, Sethi JK, O'Rahilly S, Brindle K, Cinti S, Oresic M, Burcelin R, Vidal-Puig A.

Diabetes. 2005 Jun;54(6):1706-16.PMID: 15919792 [PubMed - indexed for MEDLINE]Related articlesFree article

The incretins: a link between nutrients and well-being.

Burcelin R.

Br J Nutr. 2005 Apr;93 Suppl 1:S147-56. Review.PMID: 15877888 [PubMed - indexed for MEDLINE]Related articles

Essential role of chicken ovalbumin upstream promoter-transcription factor II in insulin secretion and insulin sensitivity revealed by conditional gene knockout.

Bardoux P, Zhang P, Flamez D, Perilhou A, Lavin TA, Tanti JF, Hellemans K, Gomas E, Godard C, Andreelli F, Buccheri MA, Kahn A, Le Marchand-Brustel Y, Burcelin R, Schuit F, Vasseur-Cognet M.

Diabetes. 2005 May;54(5):1357-63.PMID: 15855320 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation.

Gremlich S, Nolan C, Roduit R, Burcelin R, Peyot ML, Delghingaro-Augusto V, Desvergne B, Michalik L, Prentki M, Wahli W.

Endocrinology. 2005 Jan;146(1):375-82. Epub 2004 Sep 30.PMID: 15459119 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcript profiling suggests that differential metabolic adaptation of mice to a high fat diet is associated with changes in liver to muscle lipid fluxes.

de Fourmestraux V, Neubauer H, Poussin C, Farmer P, Falquet L, Burcelin R, Delorenzi M, Thorens B.

J Biol Chem. 2004 Dec 3;279(49):50743-53. Epub 2004 Sep 17.PMID: 15377667 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM.

Ma D, Shield JP, Dean W, Leclerc I, Knauf C, Burcelin R R, Rutter GA, Kelsey G.

J Clin Invest. 2004 Aug;114(3):339-48.PMID: 15286800 [PubMed - indexed for MEDLINE]Related articlesFree article

Partial gene deletion of endothelial nitric oxide synthase predisposes to exaggerated high-fat diet-induced insulin resistance and arterial hypertension.

Cook S, Hugli O, Egli M, Ménard B, Thalmann S, Sartori C, Perrin C, Nicod P, Thorens B, Vollenweider P, Scherrer U, Burcelin R.

Diabetes. 2004 Aug;53(8):2067-72.PMID: 15277387 [PubMed - indexed for MEDLINE]Related articlesFree article

Hawthorn evokes a potent anti-hyperglycemic capacity in streptozotocin-induced diabetic rats.

Jouad H, Lemhadri A, Maghrani M, Burcelin R, Eddouks M.

J Herb Pharmacother. 2003;3(2):19-29.PMID: 15277062 [PubMed]Related articles

Normal insulin sensitivity during the late preclinical stage of type 1 diabetes.

Larger E, Rakotoambinina B, Eddouks M, Timsit J, Boitard C, Assan R, Burcelin R, Robert JJ.

Diabetes Care. 2004 Jul;27(7):1842-3. No abstract available. Erratum in: Diabetes Care. 2004 Oct;27(10):2573. Rakotoaminina, Benjamin [corrected to Rakotoambinina, Benjamin]. PMID: 15220282 [PubMed - indexed for MEDLINE]Related articlesFree article