PubMed

Thiazolidinedione insulin sensitizers and the heart: a tale of two organs?

Buckingham RE, Hanna A.

Diabetes Obes Metab. 2008 Apr;10(4):312-28. Review.PMID: 18333890 [PubMed - indexed for MEDLINE]Related articles

Energy restriction enhances therapeutic efficacy of the PPARgamma agonist, rosiglitazone, through regulation of visceral fat gene expression.

Moore GB, Pickavance LC, Briscoe CP, Clapham JC, Buckingham RE, Wilding JP.

Diabetes Obes Metab. 2008 Mar;10(3):251-63.PMID: 18269641 [PubMed - indexed for MEDLINE]Related articles

Thiazolidinediones and their fluid-related adverse effects: facts, fiction and putative management strategies.

Karalliedde J, Buckingham RE.

Drug Saf. 2007;30(9):741-53. Review.PMID: 17722967 [PubMed - indexed for MEDLINE]Related articles

Thiazolidinediones: Pleiotropic drugs with potent anti-inflammatory properties for tissue protection.

Buckingham RE.

Hepatol Res. 2005 Oct;33(2):167-70. Epub 2005 Sep 29.PMID: 16198619 [PubMed - in process]Related articles

Mechanical stretch induces monocyte chemoattractant activity via an NF-kappaB-dependent monocyte chemoattractant protein-1-mediated pathway in human mesangial cells: inhibition by rosiglitazone.

Gruden G, Setti G, Hayward A, Sugden D, Duggan S, Burt D, Buckingham RE, Gnudi L, Viberti G.

J Am Soc Nephrol. 2005 Mar;16(3):688-96. Epub 2005 Jan 26.PMID: 15677312 [PubMed - indexed for MEDLINE]Related articlesFree article

Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes.

Scheuermann-Freestone M, Madsen PL, Manners D, Blamire AM, Buckingham RE, Styles P, Radda GK, Neubauer S, Clarke K.

Circulation. 2003 Jun 24;107(24):3040-6. Epub 2003 Jun 16.PMID: 12810608 [PubMed - indexed for MEDLINE]Related articlesFree article

Rapid reversal of hepatic steatosis, and reduction of muscle triglyceride, by rosiglitazone: MRI/S studies in Zucker fatty rats.

Hockings PD, Changani KK, Saeed N, Reid DG, Birmingham J, O'Brien P, Osborne J, Toseland CN, Buckingham RE.

Diabetes Obes Metab. 2003 Jul;5(4):234-43.PMID: 12795656 [PubMed - indexed for MEDLINE]Related articles

Development and analysis of a new certifying examination in perioperative transesophageal echocardiography.

Aronson S, Butler A, Subhiyah R, Buckingham RE Jr, Cahalan MK, Konstandt S, Mark J, Ramsay J, Savage R, Savino J, Shanewise JS, Smith J, Thys D.

Anesth Analg. 2002 Dec;95(6):1476-82, table of contents.PMID: 12456404 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone, a peroxisome proliferator-activated receptor-gamma, inhibits the Jun NH(2)-terminal kinase/activating protein 1 pathway and protects the heart from ischemia/reperfusion injury.

Khandoudi N, Delerive P, Berrebi-Bertrand I, Buckingham RE, Staels B, Bril A.

Diabetes. 2002 May;51(5):1507-14.PMID: 11978649 [PubMed - indexed for MEDLINE]Related articlesFree article

Thiazolidinedione treatment normalizes insulin resistance and ischemic injury in the zucker Fatty rat heart.

Sidell RJ, Cole MA, Draper NJ, Desrois M, Buckingham RE, Clarke K.

Diabetes. 2002 Apr;51(4):1110-7.PMID: 11916933 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of chronic murine and human leptin infusion on plasma leptin and corticosterone levels and energy balance in lean Zucker rats.

Al-Barazanji KA, Buckingham RE, Arch JR, Briscoe C, Jenkins O, Tadayyon M.

Diabetes Obes Metab. 2001 Dec;3(6):435-42.PMID: 11903416 [PubMed - indexed for MEDLINE]Related articles

In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone.

Yue Tl TL, Chen J, Bao W, Narayanan PK, Bril A, Jiang W, Lysko PG, Gu JL, Boyce R, Zimmerman DM, Hart TK, Buckingham RE, Ohlstein EH.

Circulation. 2001 Nov 20;104(21):2588-94.PMID: 11714655 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-sensitizing action of rosiglitazone is enhanced by preventing hyperphagia.

Pickavance LC, Buckingham RE, Wilding JP.

Diabetes Obes Metab. 2001 Jun;3(3):171-80.PMID: 11412281 [PubMed - indexed for MEDLINE]Related articles

Beta-cell mass dynamics in Zucker diabetic fatty rats. Rosiglitazone prevents the rise in net cell death.

Finegood DT, McArthur MD, Kojwang D, Thomas MJ, Topp BG, Leonard T, Buckingham RE.

Diabetes. 2001 May;50(5):1021-9.PMID: 11334404 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone prevents the onset of hyperglycaemia and proteinuria in the Zucker diabetic fatty rat.

Smith SA, Lister CA, Toseland CD, Buckingham RE.

Diabetes Obes Metab. 2000 Dec;2(6):363-72.PMID: 11225966 [PubMed - indexed for MEDLINE]Related articles

Effect of chronic central infusion of murine and human leptin in lean Zucker rats.

Al-Barazanji KA, Buckingham RE, Tadayyon M, Arch JR.

Int J Obes Relat Metab Disord. 2000 Jun;24 Suppl 2:S127-8. No abstract available. PMID: 10997629 [PubMed - indexed for MEDLINE]Related articles

Central exendin-4 infusion reduces body weight without altering plasma leptin in (fa/fa) Zucker rats.

Al-Barazanji KA, Arch JR, Buckingham RE, Tadayyon M.

Obes Res. 2000 Jul;8(4):317-23.PMID: 10933308 [PubMed - indexed for MEDLINE]Related articles

Down-regulation of orexin gene expression by severe obesity in the rats: studies in Zucker fatty and zucker diabetic fatty rats and effects of rosiglitazone.

Cai XJ, Lister CA, Buckingham RE, Pickavance L, Wilding J, Arch JR, Wilson S, Williams G.

Brain Res Mol Brain Res. 2000 Apr 14;77(1):131-7.PMID: 10814839 [PubMed - indexed for MEDLINE]Related articles

Differential distribution of orexin-A and orexin-B immunoreactivity in the rat brain and spinal cord.

Cutler DJ, Morris R, Sheridhar V, Wattam TA, Holmes S, Patel S, Arch JR, Wilson S, Buckingham RE, Evans ML, Leslie RA, Williams G.

Peptides. 1999 Dec;20(12):1455-70.PMID: 10698122 [PubMed - indexed for MEDLINE]Related articles

Therapeutic index for rosiglitazone in dietary obese rats: separation of efficacy and haemodilution.

Pickavance LC, Tadayyon M, Widdowson PS, Buckingham RE, Wilding JP.

Br J Pharmacol. 1999 Dec;128(7):1570-6.PMID: 10602338 [PubMed - indexed for MEDLINE]Related articlesFree article

Differences between the vasorelaxant activity of adenosine-receptor agonists on guinea-pig isolated aorta precontracted with noradrenaline or phenylephrine.

Ford WR, Maddock HL, Buckingham RE, Broadley KJ.

J Pharm Pharmacol. 1999 Oct;51(10):1183-90.PMID: 10579690 [PubMed - indexed for MEDLINE]Related articles

Hypothalamic orexin expression: modulation by blood glucose and feeding.

Cai XJ, Widdowson PS, Harrold J, Wilson S, Buckingham RE, Arch JR, Tadayyon M, Clapham JC, Wilding J, Williams G.

Diabetes. 1999 Nov;48(11):2132-7.PMID: 10535445 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of single and chronic intracerebroventricular administration of the orexins on feeding in the rat.

Haynes AC, Jackson B, Overend P, Buckingham RE, Wilson S, Tadayyon M, Arch JR.

Peptides. 1999;20(9):1099-105.PMID: 10499428 [PubMed - indexed for MEDLINE]Related articles

The thiazolidinedione rosiglitazone (BRL-49653) lowers blood pressure and protects against impairment of endothelial function in Zucker fatty rats.

Walker AB, Chattington PD, Buckingham RE, Williams G.

Diabetes. 1999 Jul;48(7):1448-53.PMID: 10389852 [PubMed - indexed for MEDLINE]Related articlesFree article

Indices of carbohydrate and lipid metabolism in vasopressin-replete and -deficient New Zealand genetically hypertensive rats.

Al-Barazanji KA, Buckingham RE, Balment RJ.

Horm Metab Res. 1998 Dec;30(12):717-20.PMID: 9930628 [PubMed - indexed for MEDLINE]Related articles

Characterisation of the neuropeptide Y receptor that mediates feeding in the rat: a role for the Y5 receptor?

Haynes AC, Arch JR, Wilson S, McClue S, Buckingham RE.

Regul Pept. 1998 Sep 25;75-76:355-61.PMID: 9802429 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, protects against nephropathy and pancreatic islet abnormalities in Zucker fatty rats.

Buckingham RE, Al-Barazanji KA, Toseland CD, Slaughter M, Connor SC, West A, Bond B, Turner NC, Clapham JC.

Diabetes. 1998 Aug;47(8):1326-34.PMID: 9703335 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential vasoactive effects of the insulin sensitizers rosiglitazone (BRL 49653) and troglitazone on human small arteries in vitro.

Walker AB, Naderali EK, Chattington PD, Buckingham RE, Williams G.

Diabetes. 1998 May;47(5):810-4.PMID: 9588454 [PubMed - indexed for MEDLINE]Related articlesFree article

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richarson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M.

Cell. 1998 Mar 6;92(5):1 page following 696. No abstract available. PMID: 9527442 [PubMed - indexed for MEDLINE]Related articles

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richardson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M.

Cell. 1998 Feb 20;92(4):573-85.PMID: 9491897 [PubMed - indexed for MEDLINE]Related articles

Effects of intracerebroventricular infusion of leptin in obese Zucker rats.

al-Barazanji KA, Buckingham RE, Arch JR, Haynes A, Mossakowska DE, McBay DL, Holmes SD, McHale MT, Wang XM, Gloger IS.

Obes Res. 1997 Sep;5(5):387-94.PMID: 9385611 [PubMed - indexed for MEDLINE]Related articles

Impaired insulin-induced attenuation of noradrenaline-mediated vasoconstriction in insulin-resistant obese Zucker rats.

Walker AB, Dores J, Buckingham RE, Savage MW, Williams G.

Clin Sci (Lond). 1997 Sep;93(3):235-41.PMID: 9337638 [PubMed - indexed for MEDLINE]Related articles

Functional characterisation of the neuropeptide Y receptor mediating feeding in the rat.

Haynes AC, al-Barazanji KA, Buckingham RE, Arch JR, Gott AL, McClue SJ, Wilson S.

Biochem Soc Trans. 1996 May;24(2):286S. No abstract available. PMID: 8736944 [PubMed - indexed for MEDLINE]Related articles

Treatment with the thiazolidinedione (BRL 49653) decreases insulin resistance in obese Zucker hindlimb.

Eldershaw TP, Rattigan S, Cawthorne MA, Buckingham RE, Colquhoun EQ, Clark MG.

Horm Metab Res. 1995 Apr;27(4):169-72.PMID: 7750898 [PubMed - indexed for MEDLINE]Related articles

Potential defect in the vascular control of nonshivering thermogenesis in the obese Zucker rat hind limb.

Eldershaw TP, Rattigan S, Dora KA, Colquhoun EQ, Clark MG, Cawthorne MA, Buckingham RE.

Can J Physiol Pharmacol. 1994 Dec;72(12):1567-73.PMID: 7736349 [PubMed - indexed for MEDLINE]Related articles

Mitral insufficiency after pericardiectomy for constrictive pericarditis.

Buckingham RE Jr, Furnary AP, Weaver MT, Floten HS, Davis RF.

Ann Thorac Surg. 1994 Oct;58(4):1171-4.PMID: 7944776 [PubMed - indexed for MEDLINE]Related articles

Antihypertensive and haemodynamic properties of the potassium channel activating (-) enantiomer of cromakalim in animal models.

Clapham JC, Hamilton TC, Longman SD, Buckingham RE, Campbell CA, Ilsley GL, Gout B.

Arzneimittelforschung. 1991 Apr;41(4):385-91.PMID: 1907150 [PubMed - indexed for MEDLINE]Related articles

Inhibition by glibenclamide of the vasorelaxant action of cromakalim in the rat.

Buckingham RE, Hamilton TC, Howlett DR, Mootoo S, Wilson C.

Br J Pharmacol. 1989 May;97(1):57-64.PMID: 2497925 [PubMed - indexed for MEDLINE]Related articlesFree article

Case 1989-1. A 55-year-old male undergoing CABG develops severe bronchospasm at the end of cardiopulmonary bypass.

Buckingham RE Jr, Rogers TR, Sampson IH.

J Cardiothorac Anesth. 1989 Feb;3(1):109-18. No abstract available. PMID: 2520628 [PubMed - indexed for MEDLINE]Related articles

Studies on the anti-vasoconstrictor activity of BRL 34915 in spontaneously hypertensive rats; a comparison with nifedipine.

Buckingham RE.

Br J Pharmacol. 1988 Mar;93(3):541-52.PMID: 3370388 [PubMed - indexed for MEDLINE]Related articlesFree article

The haemodynamic profile of cromakalim in the cat.

Clapham JC, Buckingham RE.

J Cardiovasc Pharmacol. 1988;12(5):555-61.PMID: 2468055 [PubMed - indexed for MEDLINE]Related articles

Alpha 1-adrenoceptor-mediated contraction of rabbit mesenteric artery: a role for intra- and extracellular calcium pools.

Wilson C, Cooper SM, Buckingham RE, Clapham JC.

J Cardiovasc Pharmacol. 1987 Apr;9(4):401-6.PMID: 2438502 [PubMed - indexed for MEDLINE]Related articles

Synthesis and antihypertensive activity of 4-(cyclic amido)-2H-1-benzopyrans.

Ashwood VA, Buckingham RE, Cassidy F, Evans JM, Faruk EA, Hamilton TC, Nash DJ, Stemp G, Willcocks K.

J Med Chem. 1986 Nov;29(11):2194-201.PMID: 3783581 [PubMed - indexed for MEDLINE]Related articles

BRL 34915, a novel antihypertensive agent: comparison of effects on blood pressure and other haemodynamic parameters with those of nifedipine in animal models.

Buckingham RE, Clapham JC, Hamilton TC, Longman SD, Norton J, Poyser RH.

J Cardiovasc Pharmacol. 1986 Jul-Aug;8(4):798-804.PMID: 2427821 [PubMed - indexed for MEDLINE]Related articles

Comparison of the anti-hypertensive response to beta-adrenoceptor blocking drugs in intact and adrenal-demedullated spontaneously hypertensive rats.

Buckingham RE, Hamilton TC.

Br J Pharmacol. 1980 Apr;68(4):667-76.PMID: 6103721 [PubMed - indexed for MEDLINE]Related articlesFree article

beta-Adrenoceptor blocking drugs and hypertension.

Buckingham RE, Hamilton TC.

Gen Pharmacol. 1979;10(1):1-13. Review. No abstract available. PMID: 33100 [PubMed - indexed for MEDLINE]Related articles

Hypotension associated with prekallikrein activator (Hageman-factor fragments) in plasma protein fraction.

Alving BM, Hojima Y, Pisano JJ, Mason BL, Buckingham RE Jr, Mozen MM, Finlayson JS.

N Engl J Med. 1978 Jul 13;299(2):66-70.PMID: 661863 [PubMed - indexed for MEDLINE]Related articles

Diminishing hypotensive effect of increasing doses of pindolol in DOCA/saline hypertensive rats.

Buckingham RE, Hamilton TC, Robson D.

Br J Pharmacol. 1978 Mar;62(3):362-3.PMID: 638315 [PubMed - indexed for MEDLINE]Related articlesFree article

Studies on the cardiovascular effects of pindolol in DOCA/saline hypertensive rats.

Buckingham RE, Hamilton TC, Robson D.

Br J Pharmacol. 1977 Jul;60(3):461-9.PMID: 19118 [PubMed - indexed for MEDLINE]Related articlesFree article

Indwelling catheters for direct recording of arterial blood pressure and intravenous injection of drugs in the conscious rat.

Buckingham RE.

J Pharm Pharmacol. 1976 May;28(5):459-61. No abstract available. PMID: 6764 [PubMed - indexed for MEDLINE]Related articles