PubMed

Influence of Membrane CD25 Stability on T Lymphocyte Activity: Implications for Immunoregulation.

Brusko TM, Wasserfall CH, Hulme MA, Cabrera R, Schatz D, Atkinson MA.

PLoS One. 2009 Nov 24;4(11):e7980.PMID: 19956753 [PubMed - in process]Free article

Regulatory T cells directed to the site of the action.

Brusko TM, Bluestone JA.

Proc Natl Acad Sci U S A. 2009 Dec 1. [Epub ahead of print] No abstract available. PMID: 19955436 [PubMed - as supplied by publisher]Related articles

Autologous umbilical cord blood transfusion in very young children with type 1 diabetes.

Haller MJ, Wasserfall CH, McGrail KM, Cintron M, Brusko TM, Wingard JR, Kelly SS, Shuster JJ, Atkinson MA, Schatz DA.

Diabetes Care. 2009 Nov;32(11):2041-6.PMID: 19875605 [PubMed - in process]Related articles

Mesenchymal stem cells: a potential border patrol for transplanted islets?

Brusko TM.

Diabetes. 2009 Aug;58(8):1728-9. No abstract available. PMID: 19638531 [PubMed - indexed for MEDLINE]Related articlesFree article

Exendin-4 therapy in NOD mice with new-onset diabetes increases regulatory T cell frequency.

Xue S, Wasserfall CH, Parker M, Brusko TM, McGrail S, McGrail K, Moore M, Campbell-Thompson M, Schatz DA, Atkinson MA, Haller MJ.

Ann N Y Acad Sci. 2008 Dec;1150:152-6.PMID: 19120286 [PubMed - indexed for MEDLINE]Related articles

Expansion of human regulatory T-cells from patients with type 1 diabetes.

Putnam AL, Brusko TM, Lee MR, Liu W, Szot GL, Ghosh T, Atkinson MA, Bluestone JA.

Diabetes. 2009 Mar;58(3):652-62. Epub 2008 Dec 15.PMID: 19074986 [PubMed - indexed for MEDLINE]Related articlesFree article

CFTR mutations impart elevated immune reactivity in a murine model of cystic fibrosis related diabetes.

Stalvey MS, Brusko TM, Mueller C, Wasserfall CH, Schatz DA, Atkinson MA, Flotte TR.

Cytokine. 2008 Oct;44(1):154-9. Epub 2008 Sep 7.PMID: 18778952 [PubMed - indexed for MEDLINE]Related articles

Human regulatory T cells: role in autoimmune disease and therapeutic opportunities.

Brusko TM, Putnam AL, Bluestone JA.

Immunol Rev. 2008 Jun;223:371-90. Review. Erratum in: Immunol Rev. 2009 May;229(1):388. PMID: 18613848 [PubMed - indexed for MEDLINE]Related articles

Suppression by CD4+CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen-presenting cells.

George JF, Braun A, Brusko TM, Joseph R, Bolisetty S, Wasserfall CH, Atkinson MA, Agarwal A, Kapturczak MH.

Am J Pathol. 2008 Jul;173(1):154-60. Epub 2008 May 29.PMID: 18511516 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical application of regulatory T cells for treatment of type 1 diabetes and transplantation.

Brusko T, Bluestone J.

Eur J Immunol. 2008 Apr;38(4):931-4.PMID: 18395864 [PubMed - indexed for MEDLINE]Related articles

Autologous umbilical cord blood infusion for type 1 diabetes.

Haller MJ, Viener HL, Wasserfall C, Brusko T, Atkinson MA, Schatz DA.

Exp Hematol. 2008 Jun;36(6):710-5. Epub 2008 Mar 20. Review.PMID: 18358588 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessing the in vitro suppressive capacity of regulatory T cells.

Brusko TM, Hulme MA, Myhr CB, Haller MJ, Atkinson MA.

Immunol Invest. 2007;36(5-6):607-28. Review.PMID: 18161521 [PubMed - indexed for MEDLINE]Related articles

Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation.

Simon G, Parker M, Ramiya V, Wasserfall C, Huang Y, Bresson D, Schwartz RF, Campbell-Thompson M, Tenace L, Brusko T, Xue S, Scaria A, Lukason M, Eisenbeis S, Williams J, Clare-Salzler M, Schatz D, Kaplan B, Von Herrath M, Womer K, Atkinson MA.

Diabetes. 2008 Feb;57(2):405-14. Epub 2007 Nov 26.PMID: 18039815 [PubMed - indexed for MEDLINE]Related articlesFree article

Treg in type 1 diabetes.

Brusko T, Atkinson M.

Cell Biochem Biophys. 2007;48(2-3):165-75. Review.PMID: 17709886 [PubMed - indexed for MEDLINE]Related articles

Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

Lowe CE, Cooper JD, Brusko T, Walker NM, Smyth DJ, Bailey R, Bourget K, Plagnol V, Field S, Atkinson M, Clayton DG, Wicker LS, Todd JA.

Nat Genet. 2007 Sep;39(9):1074-82. Epub 2007 Aug 5.PMID: 17676041 [PubMed - indexed for MEDLINE]Related articles

No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes.

Brusko T, Wasserfall C, McGrail K, Schatz R, Viener HL, Schatz D, Haller M, Rockell J, Gottlieb P, Clare-Salzler M, Atkinson M.

Diabetes. 2007 Mar;56(3):604-12.PMID: 17327427 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of HKE2: an ancient antigen encoded in the major histocompatibility complex.

Ostrov DA, Barnes CL, Smith LE, Binns S, Brusko TM, Brown AC, Quint PS, Litherland SA, Roopenian DC, Iczkowski KA.

Tissue Antigens. 2007 Feb;69(2):181-8.PMID: 17257322 [PubMed - indexed for MEDLINE]Related articles

Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis.

Scumpia PO, Delano MJ, Kelly KM, O'Malley KA, Efron PA, McAuliffe PF, Brusko T, Ungaro R, Barker T, Wynn JL, Atkinson MA, Reeves WH, Salzler MJ, Moldawer LL.

J Immunol. 2006 Dec 1;177(11):7943-9.PMID: 17114466 [PubMed - indexed for MEDLINE]Related articlesFree article

A case of unfulfilled expectations. Cytokines in idiopathic minimal lesion nephrotic syndrome.

Araya CE, Wasserfall CH, Brusko TM, Mu W, Segal MS, Johnson RJ, Garin EH.

Pediatr Nephrol. 2006 May;21(5):603-10. Epub 2006 Mar 7. Review.PMID: 16525836 [PubMed - indexed for MEDLINE]Related articles

PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21).

Burkhardt BR, Greene SR, White P, Wong RK, Brestelli JE, Yang J, Robert CE, Brusko TM, Wasserfall CH, Wu J, Atkinson MA, Gao Z, Kaestner KH, Wolf BA.

Gene. 2006 Mar 15;369:134-41. Epub 2006 Jan 18.PMID: 16412588 [PubMed - indexed for MEDLINE]Related articles

Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes.

Brusko TM, Wasserfall CH, Clare-Salzler MJ, Schatz DA, Atkinson MA.

Diabetes. 2005 May;54(5):1407-14.PMID: 15855327 [PubMed - indexed for MEDLINE]Related articlesFree article

An integral role for heme oxygenase-1 and carbon monoxide in maintaining peripheral tolerance by CD4+CD25+ regulatory T cells.

Brusko TM, Wasserfall CH, Agarwal A, Kapturczak MH, Atkinson MA.

J Immunol. 2005 May 1;174(9):5181-6. Review.PMID: 15843512 [PubMed - indexed for MEDLINE]Related articlesFree article

Radial artery tonometry demonstrates arterial stiffness in children with type 1 diabetes.

Haller MJ, Samyn M, Nichols WW, Brusko T, Wasserfall C, Schwartz RF, Atkinson M, Shuster JJ, Pierce GL, Silverstein JH.

Diabetes Care. 2004 Dec;27(12):2911-7.PMID: 15562206 [PubMed - indexed for MEDLINE]Related articlesFree article

Presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice.

You S, Chen C, Lee WH, Brusko T, Atkinson M, Liu CP.

J Immunol. 2004 Dec 1;173(11):6777-85.PMID: 15557171 [PubMed - indexed for MEDLINE]Related articlesFree article

Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse.

Kapturczak MH, Wasserfall C, Brusko T, Campbell-Thompson M, Ellis TM, Atkinson MA, Agarwal A.

Am J Pathol. 2004 Sep;165(3):1045-53. Erratum in: Am J Pathol. 2006 Feb;168(2):714. PMID: 15331427 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin and leptin concentrations may aid in discriminating disease forms in children and adolescents with type 1 and type 2 diabetes.

Morales A, Wasserfall C, Brusko T, Carter C, Schatz D, Silverstein J, Ellis T, Atkinson M.

Diabetes Care. 2004 Aug;27(8):2010-4.PMID: 15277432 [PubMed - indexed for MEDLINE]Related articlesFree article

A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes.

Guo D, Li M, Zhang Y, Yang P, Eckenrode S, Hopkins D, Zheng W, Purohit S, Podolsky RH, Muir A, Wang J, Dong Z, Brusko T, Atkinson M, Pozzilli P, Zeidler A, Raffel LJ, Jacob CO, Park Y, Serrano-Rios M, Larrad MT, Zhang Z, Garchon HJ, Bach JF, Rotter JI, She JX, Wang CY.

Nat Genet. 2004 Aug;36(8):837-41. Epub 2004 Jul 11. Erratum in: Nat Genet. 2004 Sep;36(9):1024. PMID: 15247916 [PubMed - indexed for MEDLINE]Related articles

Immunity to adeno-associated virus serotype 2 delivered transgenes imparted by genetic predisposition to autoimmunity.

Zhang YC, Powers M, Wasserfall C, Brusko T, Song S, Flotte T, Snyder RO, Potter M, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Nick HS, Agarwal A, Ellis TM, Atkinson MA.

Gene Ther. 2004 Feb;11(3):233-40.PMID: 14737082 [PubMed - indexed for MEDLINE]Related articles

Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion.

Goudy KS, Burkhardt BR, Wasserfall C, Song S, Campbell-Thompson ML, Brusko T, Powers MA, Clare-Salzler MJ, Sobel ES, Ellis TM, Flotte TR, Atkinson MA.

J Immunol. 2003 Sep 1;171(5):2270-8.PMID: 12928371 [PubMed - indexed for MEDLINE]Related articlesFree article

Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice.

Zhang YC, Pileggi A, Agarwal A, Molano RD, Powers M, Brusko T, Wasserfall C, Goudy K, Zahr E, Poggioli R, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Nick H, Flotte T, Ellis TM, Ricordi C, Inverardi L, Atkinson MA.

Diabetes. 2003 Mar;52(3):708-16.PMID: 12606512 [PubMed - indexed for MEDLINE]Related articlesFree article