PubMed

The Rho Guanosine 5'-Triphosphatase, Cell Division Cycle 42, Is Required for Insulin-Induced Actin Remodeling and Glucagon-Like Peptide-1 Secretion in the Intestinal Endocrine L Cell.

Lim GE, Xu M, Sun J, Jin T, Brubaker PL.

Endocrinology. 2009 Oct 9. [Epub ahead of print]PMID: 19819966 [PubMed - as supplied by publisher]Related articles

Carcinogenic effects of exogenous and endogenous glucagon-like peptide-2 in azoxymethane-treated mice.

Iakoubov R, Lauffer LM, Trivedi S, Kim YI, Brubaker PL.

Endocrinology. 2009 Sep;150(9):4033-43. Epub 2009 Jun 4.PMID: 19497974 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-2 increases intestinal lipid absorption and chylomicron production via CD36.

Hsieh J, Longuet C, Maida A, Bahrami J, Xu E, Baker CL, Brubaker PL, Drucker DJ, Adeli K.

Gastroenterology. 2009 Sep;137(3):997-1005, 1005.e1-4. Epub 2009 May 29.PMID: 19482026 [PubMed - indexed for MEDLINE]Related articles

GPR119 is essential for oleoylethanolamide-induced glucagon-like peptide-1 secretion from the intestinal enteroendocrine L-cell.

Lauffer LM, Iakoubov R, Brubaker PL.

Diabetes. 2009 May;58(5):1058-66. Epub 2009 Feb 10.PMID: 19208912 [PubMed - indexed for MEDLINE]Related articlesFree article

Epac is involved in cAMP-stimulated proglucagon expression and hormone production but not hormone secretion in pancreatic alpha- and intestinal L-cell lines.

Islam D, Zhang N, Wang P, Li H, Brubaker PL, Gaisano HY, Wang Q, Jin T.

Am J Physiol Endocrinol Metab. 2009 Jan;296(1):E174-81. Epub 2008 Oct 14.PMID: 18854429 [PubMed - indexed for MEDLINE]Related articles

Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell.

Lim GE, Huang GJ, Flora N, LeRoith D, Rhodes CJ, Brubaker PL.

Endocrinology. 2009 Feb;150(2):580-91. Epub 2008 Sep 25.PMID: 18818290 [PubMed - indexed for MEDLINE]Related articles

GPR119: "double-dipping" for better glycemic control.

Lauffer L, Iakoubov R, Brubaker PL.

Endocrinology. 2008 May;149(5):2035-7. No abstract available. PMID: 18427153 [PubMed - indexed for MEDLINE]Related articlesFree article

Life in the crypt: a role for glucagon-like peptide-2?

Rowland KJ, Brubaker PL.

Mol Cell Endocrinol. 2008 Jun 25;288(1-2):63-70. Epub 2008 Feb 29. Review.PMID: 18403107 [PubMed - indexed for MEDLINE]Related articles

Cross talk between the insulin and Wnt signaling pathways: evidence from intestinal endocrine L cells.

Yi F, Sun J, Lim GE, Fantus IG, Brubaker PL, Jin T.

Endocrinology. 2008 May;149(5):2341-51. Epub 2008 Feb 7.PMID: 18258680 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-2 activates beta-catenin signaling in the mouse intestinal crypt: role of insulin-like growth factor-I.

Dubé PE, Rowland KJ, Brubaker PL.

Endocrinology. 2008 Jan;149(1):291-301. Epub 2007 Sep 20.PMID: 17884945 [PubMed - indexed for MEDLINE]Related articlesFree article

Frontiers in glucagon-like peptide-2: multiple actions, multiple mediators.

Dubé PE, Brubaker PL.

Am J Physiol Endocrinol Metab. 2007 Aug;293(2):E460-5. Epub 2007 Jul 24. Review.PMID: 17652153 [PubMed - indexed for MEDLINE]Related articlesFree article

Incretin-based therapies: mimetics versus protease inhibitors.

Brubaker PL.

Trends Endocrinol Metab. 2007 Aug;18(6):240-5. Epub 2007 Jul 12. Review.PMID: 17629492 [PubMed - indexed for MEDLINE]Related articles

Role of glial cell-line derived neurotropic factor family receptor alpha2 in the actions of the glucagon-like peptides on the murine intestine.

McDonagh SC, Lee J, Izzo A, Brubaker PL.

Am J Physiol Gastrointest Liver Physiol. 2007 Aug;293(2):G461-8. Epub 2007 Jun 21.PMID: 17585017 [PubMed - indexed for MEDLINE]Related articlesFree article

A mathematical model of the oral glucose tolerance test illustrating the effects of the incretins.

Brubaker PL, Ohayon EL, D'Alessandro LM, Norwich KH.

Ann Biomed Eng. 2007 Jul;35(7):1286-300. Epub 2007 Mar 29.PMID: 17393338 [PubMed - indexed for MEDLINE]Related articles

Role of phosphatidylinositol-3 kinase-gamma in the actions of glucagon-like peptide-2 on the murine small intestine.

Anini Y, Izzo A, Oudit GY, Backx PH, Brubaker PL.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1599-606. Epub 2007 Feb 6.PMID: 17284578 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase Czeta is required for oleic acid-induced secretion of glucagon-like peptide-1 by intestinal endocrine L cells.

Iakoubov R, Izzo A, Yeung A, Whiteside CI, Brubaker PL.

Endocrinology. 2007 Mar;148(3):1089-98. Epub 2006 Nov 16.PMID: 17110421 [PubMed - indexed for MEDLINE]Related articlesFree article

The essential role of insulin-like growth factor-1 in the intestinal tropic effects of glucagon-like peptide-2 in mice.

Dubé PE, Forse CL, Bahrami J, Brubaker PL.

Gastroenterology. 2006 Aug;131(2):589-605. Erratum in: Gastroenterology. 2007 Mar;132(3):1208. PMID: 16890611 [PubMed - indexed for MEDLINE]Related articles

The glucagon-like peptides: pleiotropic regulators of nutrient homeostasis.

Brubaker PL.

Ann N Y Acad Sci. 2006 Jul;1070:10-26.PMID: 16888147 [PubMed - indexed for MEDLINE]Related articles

From cradle to grave: pancreatic beta-cell mass and glucagon-like peptide-1.

Wong VS, Brubaker PL.

Minerva Endocrinol. 2006 Jun;31(2):107-24. Review.PMID: 16682935 [PubMed - indexed for MEDLINE]Related articles

Role of phosphatidylinositol 3-kinasegamma in the beta-cell: interactions with glucagon-like peptide-1.

Li LX, MacDonald PE, Ahn DS, Oudit GY, Backx PH, Brubaker PL.

Endocrinology. 2006 Jul;147(7):3318-25. Epub 2006 Mar 30.PMID: 16574789 [PubMed - indexed for MEDLINE]Related articlesFree article

Adventure travel and type 1 diabetes: the complicating effects of high altitude.

Brubaker PL.

Diabetes Care. 2005 Oct;28(10):2563-72. Review. No abstract available. PMID: 16186302 [PubMed - indexed for MEDLINE]Related articlesFree article

PKA independent and cell type specific activation of the expression of caudal homeobox gene Cdx-2 by cyclic AMP.

Chen L, Wang P, Andrade CF, Zhao IY, Dubé PE, Brubaker PL, Liu M, Jin T.

FEBS J. 2005 Jun;272(11):2746-59.PMID: 15943809 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice.

Talsania T, Anini Y, Siu S, Drucker DJ, Brubaker PL.

Endocrinology. 2005 Sep;146(9):3748-56. Epub 2005 Jun 2.PMID: 15932924 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: role of protein kinase B.

Li L, El-Kholy W, Rhodes CJ, Brubaker PL.

Diabetologia. 2005 Jul;48(7):1339-49. Epub 2005 May 19.PMID: 15902400 [PubMed - indexed for MEDLINE]Related articles

Mucosal adaptation to enteral nutrients is dependent on the physiologic actions of glucagon-like peptide-2 in mice.

Shin ED, Estall JL, Izzo A, Drucker DJ, Brubaker PL.

Gastroenterology. 2005 May;128(5):1340-53. Erratum in: Gastroenterology. 2007 Mar;132(3):1208. PMID: 15887116 [PubMed - indexed for MEDLINE]Related articles

beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1.

Li Y, Cao X, Li LX, Brubaker PL, Edlund H, Drucker DJ.

Diabetes. 2005 Feb;54(2):482-91.PMID: 15677506 [PubMed - indexed for MEDLINE]Related articlesFree article

Nutrient, neural and endocrine control of glucagon-like peptide secretion.

Dubé PE, Brubaker PL.

Horm Metab Res. 2004 Nov-Dec;36(11-12):755-60. Review.PMID: 15655704 [PubMed - indexed for MEDLINE]Related articles

TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta.

Yi F, Brubaker PL, Jin T.

J Biol Chem. 2005 Jan 14;280(2):1457-64. Epub 2004 Nov 2.PMID: 15525634 [PubMed - indexed for MEDLINE]Related articlesFree article

Extrahypothalamic expression of the glucagon-like peptide-2 receptor is coupled to reduction of glutamate-induced cell death in cultured hippocampal cells.

Lovshin JA, Huang Q, Seaberg R, Brubaker PL, Drucker DJ.

Endocrinology. 2004 Jul;145(7):3495-506. Epub 2004 Apr 1.PMID: 15059959 [PubMed - indexed for MEDLINE]Related articlesFree article

Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system.

Brubaker PL, Drucker DJ.

Endocrinology. 2004 Jun;145(6):2653-9. Epub 2004 Mar 24. Review.PMID: 15044356 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells.

Wang Q, Li L, Xu E, Wong V, Rhodes C, Brubaker PL.

Diabetologia. 2004 Mar;47(3):478-87. Epub 2004 Feb 5.PMID: 14762654 [PubMed - indexed for MEDLINE]Related articles

Direct and indirect mechanisms regulating secretion of glucagon-like peptide-1 and glucagon-like peptide-2.

Brubaker PL, Anini Y.

Can J Physiol Pharmacol. 2003 Nov;81(11):1005-12. Review.PMID: 14719035 [PubMed - indexed for MEDLINE]Related articles

Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency.

Jackson RS, Creemers JW, Farooqi IS, Raffin-Sanson ML, Varro A, Dockray GJ, Holst JJ, Brubaker PL, Corvol P, Polonsky KS, Ostrega D, Becker KL, Bertagna X, Hutton JC, White A, Dattani MT, Hussain K, Middleton SJ, Nicole TM, Milla PJ, Lindley KJ, O'Rahilly S.

J Clin Invest. 2003 Nov;112(10):1550-60.PMID: 14617756 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-2 receptor activation in the rat intestinal mucosa.

Walsh NA, Yusta B, DaCambra MP, Anini Y, Drucker DJ, Brubaker PL.

Endocrinology. 2003 Oct;144(10):4385-92. Epub 2003 Jul 3.PMID: 12960094 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-2 and common therapeutics in a murine model of ulcerative colitis.

L'Heureux MC, Brubaker PL.

J Pharmacol Exp Ther. 2003 Jul;306(1):347-54.PMID: 12815012 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscarinic receptors control glucagon-like peptide 1 secretion by human endocrine L cells.

Anini Y, Brubaker PL.

Endocrinology. 2003 Jul;144(7):3244-50.PMID: 12810581 [PubMed - indexed for MEDLINE]Related articlesFree article

Pax-6 activates endogenous proglucagon gene expression in the rodent gastrointestinal epithelium.

Trinh DK, Zhang K, Hossain M, Brubaker PL, Drucker DJ.

Diabetes. 2003 Feb;52(2):425-33.PMID: 12540617 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of leptin in the regulation of glucagon-like peptide-1 secretion.

Anini Y, Brubaker PL.

Diabetes. 2003 Feb;52(2):252-9.PMID: 12540594 [PubMed - indexed for MEDLINE]Related articlesFree article

Structure-function of the glucagon receptor family of G protein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptors.

Brubaker PL, Drucker DJ.

Receptors Channels. 2002;8(3-4):179-88. Review.PMID: 12529935 [PubMed - indexed for MEDLINE]Related articles

Transcriptional activation of the proglucagon gene by lithium and beta-catenin in intestinal endocrine L cells.

Ni Z, Anini Y, Fang X, Mills G, Brubaker PL, Jin T.

J Biol Chem. 2003 Jan 10;278(2):1380-7. Epub 2002 Nov 5.PMID: 12421827 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated glucagon-like peptide-1-(7-36)-amide, but not glucose, associated with hyperinsulinemic compensation for fat feeding.

van Citters GW, Kabir M, Kim SP, Mittelman SD, Dea MK, Brubaker PL, Bergman RN.

J Clin Endocrinol Metab. 2002 Nov;87(11):5191-8.PMID: 12414891 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice.

Wang Q, Brubaker PL.

Diabetologia. 2002 Sep;45(9):1263-73. Epub 2002 Apr 26.PMID: 12242459 [PubMed - indexed for MEDLINE]Related articles

Cellular specificity of proexendin-4 processing in mammalian cells in vitro and in vivo.

Adatia FA, Baggio LL, Xiao Q, Drucker DJ, Brubaker PL.

Endocrinology. 2002 Sep;143(9):3464-71.PMID: 12193559 [PubMed - indexed for MEDLINE]Related articlesFree article

Prolonged gastrointestinal transit in a patient with a glucagon-like peptide (GLP)-1- and -2-producing neuroendocrine tumor.

Brubaker PL, Drucker DJ, Asa SL, Swallow C, Redston M, Greenberg GR.

J Clin Endocrinol Metab. 2002 Jul;87(7):3078-83.PMID: 12107204 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscarinic receptors control postprandial release of glucagon-like peptide-1: in vivo and in vitro studies in rats.

Anini Y, Hansotia T, Brubaker PL.

Endocrinology. 2002 Jun;143(6):2420-6.PMID: 12021207 [PubMed - indexed for MEDLINE]Related articlesFree article

Foxa3 (HNF-3gamma) binds to and activates the rat proglucagon gene promoter but is not essential for proglucagon gene expression.

Liu Y, Shen W, Brubaker PL, Kaestner KH, Drucker DJ.

Biochem J. 2002 Sep 1;366(Pt 2):633-41.PMID: 12000309 [PubMed - indexed for MEDLINE]Related articlesFree article

A glucagon-like peptide-1 receptor agonist and an antagonist modify macronutrient selection by rats.

Peters CT, Choi YH, Brubaker PL, Anderson GH.

J Nutr. 2001 Aug;131(8):2164-70.PMID: 11481412 [PubMed - indexed for MEDLINE]Related articlesFree article

Therapeutic potential of the intestinotropic hormone, glucagon-like peptide-2.

L'Heureux MC, Brubaker PL.

Ann Med. 2001 May;33(4):229-35. Review.PMID: 11405543 [PubMed - indexed for MEDLINE]Related articles

Biological activities of glucagon-like peptide-1 analogues in vitro and in vivo.

Xiao Q, Giguere J, Parisien M, Jeng W, St-Pierre SA, Brubaker PL, Wheeler MB.

Biochemistry. 2001 Mar 6;40(9):2860-9.PMID: 11258897 [PubMed - indexed for MEDLINE]Related articles

Monounsaturated fatty acid diets improve glycemic tolerance through increased secretion of glucagon-like peptide-1.

Rocca AS, LaGreca J, Kalitsky J, Brubaker PL.

Endocrinology. 2001 Mar;142(3):1148-55.PMID: 11181530 [PubMed - indexed for MEDLINE]Related articlesFree article